The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability

Hallacli, E., Kayatekin, C., Nazeen, S., Wang, X. H., Sheinkopf, Z., Sathyakumar, S., Sarkar, S., Jiang, X., Dong, X., Di Maio, R., Wang, W., Keeney, M. T., Felsky, D., Sandoe, J., Vahdatshoar, A., Udeshi, N. D., Mani, D. R., Carr, S. A., Lindquist, S., … Khurana, V. (2022). The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell, 185(12), 2035-2056.e33. https://doi.org/10.1016/j.cell.2022.05.008
Authors:
Erinc Hallacli
Can Kayatekin
Sumaiya Nazeen
Xiou H Wang
Zoe Sheinkopf
Shubhangi Sathyakumar
Souvarish Sarkar
Xin Jiang
Xianjun Dong
Roberto Di Maio
Wen Wang
Matthew T Keeney
Daniel Felsky
Jackson Sandoe
Aazam Vahdatshoar
Namrata D Udeshi
D R Mani
Steven A Carr
Susan Lindquist
Philip L De Jager
David P Bartel
Chad L Myers
J Timothy Greenamyre
Mel B Feany
Shamil R Sunyaev
Chee Yeun Chung
Vikram Khurana
Affiliated Authors:
Philip L De Jager
Columbia Affiliation:
Subjects:
Pathophysiology of Parkinson's Disease (OpenAlex Topic)
Functions and Regulation of RNA Editing by ADARs (OpenAlex Topic)
Regulation of RNA Processing and Function (OpenAlex Topic)
Parkinson Disease (MeSH)
alpha-Synuclein (MeSH)
Author Keywords:
alpha-synuclein
ipsc
lewy body disease
mrna degradation
mrna stability
parkinson's disease
processing bodies
rare variant
rna-binding proteins
synucleinopathy
elink
Publication Type:
Article
Unique ID:
10.1016/j.cell.2022.05.008
PMID:
35688132
DOI:
10.1016/j.cell.2022.05.008
Journal:
Cell
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: