Herbert Irving Comprehensive Cancer Center

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Liu, Y., Wu, Z., Zhou, J., Ramadurai, D. K. A., Mortenson, K. L., Aguilera-Jimenez, E., Yan, Y., Yang, X., Taylor, A. M., Varley, K. E., Gertz, J., Choi, P. S., Cherniack, A. D., Chen, X., Bass, A. J., Bailey, S. D., & Zhang, X. (2021). A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-27055-4
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Chen, V., Bo, C., & Gu, W. (2021). The roads to ferroptosis under homeostatic versus pathological conditions. Molecular & Cellular Oncology, 8(5). https://doi.org/10.1080/23723556.2021.1970477
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Cable, J., Pei, D., Reid, L. M., Wang, X. W., Bhatia, S., Karras, P., Melenhorst, J. J., Grompe, M., Lathia, J. D., Song, E., Kuo, C. J., Zhang, N., White, R. M., Ma, S. K., Ma, L., Chin, Y. R., Shen, M. M., Ng, I. O. L., Kaestner, K. H., … Weissman, I. L. (2021). Cancer stem cells: advances in biology and clinical translation—a Keystone Symposia report. Annals of the New York Academy of Sciences, 1506(1), 142–163. Portico. https://doi.org/10.1111/nyas.14719
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Pei, S., Swayne, T. C., Morris, J. F., & Emtage, L. (2021). Threshold concentration and random collision determine the growth of the huntingtin inclusion from a stable core. Communications Biology, 4(1). https://doi.org/10.1038/s42003-021-02460-z
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Houghton, L. C., Gibbons, M. P., Shekelle, J., Oakley-Girvan, I., Watterson, J. L., Magsamen-Conrad, K., Jones, C., & Gokal, K. (2021). Free Time For Wellness: a co-designed intervention utilizing social networks to encourage physical activity for cancer prevention among low resourced mothers. BMC Public Health, 21(1). https://doi.org/10.1186/s12889-021-11775-9
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Karakasheva, T. A., Gabre, J. T., Sachdeva, U. M., Cruz-Acuña, R., Lin, E. W., DeMarshall, M., Falk, G. W., Ginsberg, G. G., Yang, Z., Kim, M. M., Diffenderfer, E. S., Pitarresi, J. R., Li, J., Muir, A. B., Hamilton, K. E., Nakagawa, H., Bass, A. J., & Rustgi, A. K. (2021). Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-00706-8
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Altoe, M. L., Kalinsky, K., Marone, A., Kim, H. K., Guo, H., Hibshoosh, H., Tejada, M., Crew, K. D., Accordino, M. K., Trivedi, M. S., Hershman, D. L., & Hielscher, A. H. (2021). Effects of neoadjuvant chemotherapy on the contralateral non-tumor-bearing breast assessed by diffuse optical tomography. Breast Cancer Research, 23(1). https://doi.org/10.1186/s13058-021-01396-w
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Wu, X., Cheng, Y.-S. L., Matthen, M., Yoon, A., Schwartz, G. K., Bala, S., Taylor, A. M., & Momen-Heravi, F. (2021). Down-regulation of the tumor suppressor miR-34a contributes to head and neck cancer by up-regulating the MET oncogene and modulating tumor immune evasion. Journal of Experimental & Clinical Cancer Research, 40(1). https://doi.org/10.1186/s13046-021-01865-2
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Chen, D., Chu, B., Yang, X., Liu, Z., Jin, Y., Kon, N., Rabadan, R., Jiang, X., Stockwell, B. R., & Gu, W. (2021). iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-23902-6
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Singh, V., Pencina, M., Einstein, A. J., Liang, J. X., Berman, D. S., & Slomka, P. (2021). Impact of train/test sample regimen on performance estimate stability of machine learning in cardiovascular imaging. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-93651-5
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Kremer, D. M., Nelson, B. S., Lin, L., Yarosz, E. L., Halbrook, C. J., Kerk, S. A., Sajjakulnukit, P., Myers, A., Thurston, G., Hou, S. W., Carpenter, E. S., Andren, A. C., Nwosu, Z. C., Cusmano, N., Wisner, S., Mbah, N. E., Shan, M., Das, N. K., Magnuson, B., … Lyssiotis, C. A. (2021). GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24859-2
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Tate, T., Xiang, T., Wobker, S. E., Zhou, M., Chen, X., Kim, H., Batourina, E., Lin, C.-S., Kim, W. Y., Lu, C., Mckiernan, J. M., & Mendelsohn, C. L. (2021). Pparg signaling controls bladder cancer subtype and immune exclusion. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-26421-6
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Sheikh, T. N., Chen, X., Xu, X., McGuire, J. T., Ingham, M., Lu, C., & Schwartz, G. K. (2021). Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors. Molecular Cancer Therapeutics, 20(12), 2362–2371. https://doi.org/10.1158/1535-7163.mct-21-0066
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Austin, J. D., Tehranifar, P., Rodriguez, C. B., Brotzman, L., Agovino, M., Ziazadeh, D., Moise, N., & Shelton, R. C. (2021). A mixed-methods study of multi-level factors influencing mammography overuse among an older ethnically diverse screening population: implications for de-implementation. Implementation Science Communications, 2(1). https://doi.org/10.1186/s43058-021-00217-7
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Laszkowska, M., Kim, J., Faye, A. S., Joelson, A. M., Ingram, M., Truong, H., Silver, E. R., May, B., Greendyke, W. G., Zucker, J., Lebwohl, B., Hur, C., & Freedberg, D. E. (2021). Prevalence of Clostridioides difficile and Other Gastrointestinal Pathogens in Patients with COVID-19. Digestive Diseases and Sciences, 66(12), 4398–4405. https://doi.org/10.1007/s10620-020-06760-y
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Mi, X., Zou, B., Zou, F., & Hu, J. (2021). Permutation-based identification of important biomarkers for complex diseases via machine learning models. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-22756-2
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Zhu, N., Swietlik, E. M., Welch, C. L., Pauciulo, M. W., Hagen, J. J., Zhou, X., Guo, Y., Karten, J., Pandya, D., Tilly, T., Lutz, K. A., Martin, J. M., Treacy, C. M., Rosenzweig, E. B., Krishnan, U., Coleman, A. W., Gonzaga-Jauregui, C., Lawrie, A., Trembath, R. C., … Chung, W. K. (2021). Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. Genome Medicine, 13(1). https://doi.org/10.1186/s13073-021-00891-1
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Clement, C. C., D’Alessandro, A., Thangaswamy, S., Chalmers, S., Furtado, R., Spada, S., Mondanelli, G., Ianni, F., Gehrke, S., Gargaro, M., Manni, G., Cara, L. C. L., Runge, P., Tsai, W. L., Karaman, S., Arasa, J., Fernandez-Rodriguez, R., Beck, A., Macchiarulo, A., … Santambrogio, L. (2021). 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24785-3
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Wu, H.-C., Yang, H.-I., Lin, P.-H., Chen, C.-J., Santella, R. M., & Terry, M. B. (2021). Reproductive and environmental exposures and the breast cancer risk in Taiwanese women. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-95290-2
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Melamed, A., Rauh-Hain, J. A., Gockley, A. A., Nitecki, R., Ramirez, P. T., Hershman, D. L., Keating, N., & Wright, J. D. (2021). Association Between Overall Survival and the Tendency for Cancer Programs to Administer Neoadjuvant Chemotherapy for Patients With Advanced Ovarian Cancer. JAMA Oncology, 7(12), 1782. https://doi.org/10.1001/jamaoncol.2021.4252
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Lan, Z., Chen, L., Feng, J., Xie, Z., Liu, Z., Wang, F., Liu, P., Yue, X., Du, L., Zhao, Y., Yang, P., Luo, J., Zhu, Z., Hu, X., Cao, L., Lu, P., Sah, R., Lavine, K., Kim, B., & Hu, H. (2021). Mechanosensitive TRPV4 is required for crystal-induced inflammation. Annals of the Rheumatic Diseases, 80(12), 1604–1614. https://doi.org/10.1136/annrheumdis-2021-220295
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Iketani, S., Forouhar, F., Liu, H., Hong, S. J., Lin, F.-Y., Nair, M. S., Zask, A., Huang, Y., Xing, L., Stockwell, B. R., Chavez, A., & Ho, D. D. (2021). Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-22362-2
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Goodwin, P. J., Dowling, R. J. O., Ennis, M., Chen, B. E., Parulekar, W. R., Shepherd, L. E., Burnell, M. J., Vander Meer, R., Molckovsky, A., Gurjal, A., Gelmon, K. A., Ligibel, J. A., Hershman, D. L., Mayer, I. A., Whelan, T. J., Hobday, T. J., Rastogi, P., Rabaglio-Poretti, M., Lemieux, J., … Stambolic, V. (2021). Effect of metformin versus placebo on metabolic factors in the MA.32 randomized breast cancer trial. Npj Breast Cancer, 7(1). https://doi.org/10.1038/s41523-021-00275-z
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Flashner, S., Yan, K. S., & Nakagawa, H. (2021). 3D Organoids: An Untapped Platform for Studying Host–Microbiome Interactions in Esophageal Cancers. Microorganisms, 9(11), 2182. https://doi.org/10.3390/microorganisms9112182
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Cham, S., Li, A., Rauh-Hain, J. A., Tergas, A. I., Hershman, D. L., Wright, J. D., & Melamed, A. (2022). Association Between Neighborhood Socioeconomic Inequality and Cervical Cancer Incidence Rates in New York City. JAMA Oncology, 8(1), 159. https://doi.org/10.1001/jamaoncol.2021.5779
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Chu, J. N., Collins, J. E., Chen, T. T., Chai, P. R., Dadabhoy, F., Byrne, J. D., Wentworth, A., DeAndrea-Lazarus, I. A., Moreland, C. J., Wilson, J. A. B., Booth, A., Ghenand, O., Hur, C., & Traverso, G. (2021). Patient and Health Care Worker Perceptions of Communication and Ability to Identify Emotion When Wearing Standard and Transparent Masks. JAMA Network Open, 4(11), e2135386. https://doi.org/10.1001/jamanetworkopen.2021.35386
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Nitecki, R., Fu, S., Jorgensen, K. A., Gray, L., Lefkowits, C., Smith, B. D., Meyer, L. A., Melamed, A., Giordano, S. H., Ramirez, P. T., & Rauh-Hain, J. A. (2022). Employment disruption among women with gynecologic cancers. International Journal of Gynecological Cancer, 32(1), 69–78. https://doi.org/10.1136/ijgc-2021-002949
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Shoushtari, A. N., Khan, S., Komatsubara, K., Feun, L., Acquavella, N., Singh-Kandah, S., Negri, T., Nesson, A., Abbate, K., Cremers, S., Musi, E., Ambrosini, G., Lee, S., Schwartz, G. K., & Carvajal, R. D. (2021). A Phase Ib Study of Sotrastaurin, a PKC Inhibitor, and Alpelisib, a PI3Kα Inhibitor, in Patients with Metastatic Uveal Melanoma. Cancers, 13(21), 5504. https://doi.org/10.3390/cancers13215504
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Balasubramanian, R., Min, X., Quinn, P. M. J., Giudice, Q. L., Tao, C., Polanco, K., Makrides, N., Peregrin, J., Bouaziz, M., Mao, Y., Wang, Q., da Costa, B. L., Buenaventura, D., Wang, F., Ma, L., Tsang, S. H., Fabre, P. J., & Zhang, X. (2021). Phase transition specified by a binary code patterns the vertebrate eye cup. Science Advances, 7(46). https://doi.org/10.1126/sciadv.abj9846
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Lipsky, A. H., Hill, B. T., Winter, A. M., Jurcic, J. G., Heaney, M. L., Rosenblat, T. L., Chiaramonte, M., Weissbrot, H., & Lamanna, N. (2021). High Rates of Undetectable Minimal Residual Disease Remissions with Time-Limited Bendamustine, Rituximab, and Venetoclax (BR-VR) in Untreated Chronic Lymphocytic Leukemia (CLL). Blood, 138(Supplement 1), 1555–1555. https://doi.org/10.1182/blood-2021-150914
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Pemmaraju, N., Kantarjian, H., Sweet, K., Wang, E. S., Lane, A. A., Ali, H., Stein, A. S., Yacoub, A., Rizzieri, D. A., Vasu, S., Gupta, V., Lee, S., Schiller, G. J., Foran, J. M., Taparia, M. S., Rosenblat, T. L., Walter, R. B., Sieminski, D., Anant, M., … Konopleva, M. (2021). Integrated Safety Analysis of Tagraxofusp, a CD123-Directed Targeted Therapy, in Patients with Hematologic Malignancies. Blood, 138(Supplement 1), 2318–2318. https://doi.org/10.1182/blood-2021-145344
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Hill, B. T., Roth, C. J., Kositsky, R., Dave, T., Love, C., McKinney, M., Galal, A., Neff, J. L., Mian, A., Kendall, E., Ondrejka, S. L., Chiaramonte, M., Bhagat, G., Ofori, K., Reshef, R., Kovach, A. E., Sethi, T., Mason, E. F., Bhaskar, S., … Dave, S. S. (2021). Impact of Molecular Features of Diffuse Large B-Cell Lymphoma on Treatment Outcomes with Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy. Blood, 138(Supplement 1), 165–165. https://doi.org/10.1182/blood-2021-145764
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Estrella, B., Liu, Y., Ricker, E. C., Pazos, M. A., Fiorito, J., Zuccarello, E., Calcagno, E., Honig, B., Arancio, O., & Amengual, J. E. (2021). Histone Acetyltransferase (HAT) Activator, YF2, Modulates the p53:BCL6 Axis and Antigen Presentation in Diffuse Large B-Cell Lymphomas. Blood, 138(Supplement 1), 2254–2254. https://doi.org/10.1182/blood-2021-151442
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Scuoppo, C., Cai, B., Ofori, K., Scholze, H., Basso, K., Pasqualucci, L., & Dalla-Favera, R. (2021). Repurposing NAD Salvage Inhibitors for GCB Diffuse Large-B Cell Lymphoma. Blood, 138(Supplement 1), 789–789. https://doi.org/10.1182/blood-2021-151079
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Galan-Diez, M., Borot, F., Ali, A. M., Zhao, J., Gil-Iturbe, E., Shan, X., Huang, X.-P., Kurland, I., Roth, B. L., Quick, M., Mukherjee, S., Rabadan, R., Carroll, M. P., Raza, A., & Kousteni, S. (2021). A Targetable Bone Marrow-Niche Axis for the Treatment of Acute Myeloid Leukemia. Blood, 138(Supplement 1), 4456–4456. https://doi.org/10.1182/blood-2021-147741
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Ricker, E. C., Ryu, Y. K., & Amengual, J. E. (2021). Daratumumab Plus Chemotherapy Induces Complete Responses in a Consecutive Series of Four Patients with Plasmablastic Lymphoma. Blood, 138(Supplement 1), 4573–4573. https://doi.org/10.1182/blood-2021-150800
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Tremblay, D., Srisuwananukorn, A., Ronner, L., Podoltsev, N., Gotlib, J., Heaney, M. L., Kuykendall, A. T., O’Connell, C. L., Shammo, J. M., Fleischman, A., Mesa, R. A., Yacoub, A., Hoffman, R., Moshier, E., Zubizarreta, N., & Mascarenhas, J. (2021). European Leukemianet (ELN) Response Predicts Disease Progression but Not Thrombosis or Death in Polycythemia Vera (PV): An Analysis of a Multicenter Database. Blood, 138(Supplement 1), 240–240. https://doi.org/10.1182/blood-2021-148020
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Ricker, E. C., Estrella, B., Pazos, M. A., & Amengual, J. E. (2021). Dual Targeting of EZH2 and HDAC with Tazemetostat and Belinostat Promotes Immunogenicity in GC-DLBCL. Blood, 138(Supplement 1), 2410–2410. https://doi.org/10.1182/blood-2021-153460
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Hopson, M., Bhutani, D., Sarkaria, S. M., Maurer, M., Griffin, J., Lentzsch, S., & Chakraborty, R. (2021). Impact of Light Chain Isotype on Clinical Features and Outcomes in Systemic AL Amyloidosis. Blood, 138(Supplement 1), 4726–4726. https://doi.org/10.1182/blood-2021-149299
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Srisuwananukorn, A., Percha, B., Abu-Zeinah, G., Scandura, J., Krichevsky, S., Taylor, E., Silver, R. T., Thibaud, S., Ronner, L., Podoltsev, N., Gotlib, J., Heaney, M. L., Kuykendall, A. T., O’Connell, C., Shammo, J. M., Fleischman, A., Mesa, R. A., Yacoub, A., Hoffman, R., … Tremblay, D. (2021). Novel Machine Learning Algorithm Predicts Disease Progression in Polycythemia Vera (PV) with Readily-Available Baseline Characteristics. Blood, 138(Supplement 1), 2583–2583. https://doi.org/10.1182/blood-2021-150561
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Lue, J. K., Ma, H., Marchi, E., Spivack, J. H., & O’Connor, O. A. (2021). Peripheral T-Cell Lymphoma Involvement of the Central Nervous System: Impact of Novel Therapeutics on Clinical Outcomes. Blood, 138(Supplement 1), 2469–2469. https://doi.org/10.1182/blood-2021-144933
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De Botton, S., Yee, K., Recher, C., Wei, A. H., Montesinos, P., Taussig, D., Pigneux, A., Braun, T., Curti, A., Esteve, J., Grove, C., Jonas, B. A., Khwaja, A., Legrand, O., Peterlin, P., Arnan Sangerman, M., Blum, W. G., Cilloni, D., Hiwase, D., … Fenaux, P. (2021). Molecular Characteristics of Response to Olutasidenib (FT-2102) in Patients with Relapsed/Refractory mIDH1 Acute Myeloid Leukemia. Blood, 138(Supplement 1), 2351–2351. https://doi.org/10.1182/blood-2021-144912
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Garcia, J. S., Wei, A. H., Jacoby, M. A., Fong, C. Y., Borate, U., Baer, M. R., Cunningham, I., Odenike, O., Jurcic, J. G., Nowak, D., Peterlin, P., Platzbecker, U., Dunshee, D., Zhou, Y., Hoffman, D., Sun, Y., Popovic, R., Ainsworth, B., Naqvi, K., … Garcia-Manero, G. (2021). Molecular Responses Are Observed across Mutational Spectrum in Treatment-Naïve Higher-Risk Myelodysplastic Syndrome Patients Treated with Venetoclax Plus Azacitidine. Blood, 138(Supplement 1), 241–241. https://doi.org/10.1182/blood-2021-145613
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Lee, H. J., Choi, M., Siddiqi, T., Barrientos, J., Wierda, W. G., Isufi, I., Tuscano, J., Lamanna, N., Subbiah, S., Koff, J. L., Leslie, L. A., Goldenberg, A., Chung, G. G., Breitmeyer, J. B., Yazji, S., Wang, Y., Wang, M., Jamieson, C., & Kipps, T. J. (2021). Phase 1b/2 Study of Cirmtuzumab and Ibrutinib in Mantle Cell Lymphoma (MCL) or Chronic Lymphocytic Leukemia (CLL). Blood, 138(Supplement 1), 3534–3534. https://doi.org/10.1182/blood-2021-148779
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Crowley, L., & Shen, M. M. (2022). Heterogeneity and complexity of the prostate epithelium: New findings from single-cell RNA sequencing studies. Cancer Letters, 525, 108–114. https://doi.org/10.1016/j.canlet.2021.10.035
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Symeonides, S., Evans, J., Arkenau, H.-T., McKean, M., Lakhani, N., Lim, E., Falchook, G., Rotolo, J., Capiaux, G., Michel, R., Kaesshaefer, S., & Bexon, A. (2021). CTNI-49. PHASE 1 STUDY OF ST101, A FIRST-IN-CLASS PEPTIDE ANTAGONIST OF CCAAT/ENHANCER-BINDING PROTEIN ß, IN PATIENTS WITH ADVANCED SOLID TUMORS, WITH A PHASE 2 EXPANSION IN RECURRENT GLIOBLASTOMA MULTIFORME. Neuro-Oncology, 23(Supplement_6), vi71–vi71. https://doi.org/10.1093/neuonc/noab196.274
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