GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

Kremer, D. M., Nelson, B. S., Lin, L., Yarosz, E. L., Halbrook, C. J., Kerk, S. A., Sajjakulnukit, P., Myers, A., Thurston, G., Hou, S. W., Carpenter, E. S., Andren, A. C., Nwosu, Z. C., Cusmano, N., Wisner, S., Mbah, N. E., Shan, M., Das, N. K., Magnuson, B., … Lyssiotis, C. A. (2021). GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24859-2
Authors:
Daniel M. Kremer
Barbara S. Nelson
Lin Lin
Emily L. Yarosz
Christopher J. Halbrook
Samuel A. Kerk
Peter Sajjakulnukit
Amy Myers
Galloway Thurston
Sean W. Hou
Eileen S. Carpenter
Anthony C. Andren
Zeribe C. Nwosu
Nicholas Cusmano
Stephanie Wisner
Nneka E. Mbah
Mengrou Shan
Nupur K. Das
Brian Magnuson
Andrew C. Little
Milan R. Savani
Johanna Ramos
Tina Gao
Stephen A. Sastra
Carmine F. Palermo
Michael A. Badgley
Li Zhang
John M. Asara
Samuel K. McBrayer
Marina Pasca di Magliano
Howard C. Crawford
Yatrik M. Shah
Kenneth P. Olive
Costas A. Lyssiotis
Affiliated Authors:
Stephen A. Sastra
Carmine F. Palermo
Michael A. Badgley
Kenneth P. Olive
Columbia Affiliation:
Subjects:
Mechanisms and Implications of Ferroptosis in Cancer (OpenAlex Topic)
Epigenetic Modifications and Their Functional Implications (OpenAlex Topic)
Pancreatic Cancer Research and Treatment (OpenAlex Topic)
Aspartate Aminotransferase, Cytoplasmic (MeSH)
Ferroptosis (MeSH)
Pancreatic Neoplasms (MeSH)
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Publication Type:
Article
Unique ID:
10.1038/s41467-021-24859-2
PMID:
34381026
DOI:
10.1038/s41467-021-24859-2
Journal:
Nature Communications
Publication Date:
Data Source:
Scopus
Source Link:
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Record Created: