P30AI027757

NIH – National Institute of Allergy and Infectious Diseases

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Polytopic fractional delivery of an HIV vaccine alters cellular responses and results in increased epitope breadth in a phase 1 randomized trial

Miner, M. D., deCamp, A., Grunenberg, N., De Rosa, S. C., Fiore-Gartland, A., Bar, K., Spearman, P., Allen, M., Yu, P.-C., Manso, B., Frahm, N., Kalams, S., Baden, L., Keefer, M. C., Scott, H. M., Novak, R., Van Tieu, H., Tomaras, G. D., Kublin, J. G., … Luke-Kilolam, A. (2024). Polytopic fractional delivery of an HIV vaccine alters cellular responses and results in increased epitope breadth in a phase 1 randomized trial. EBioMedicine, 100, 104987. https://doi.org/10.1016/j.ebiom.2024.104987
Authors:
Maurine D. Miner
Allan C. deCamp
Nicole Grunenberg
Stephen C. De Rosa
Andrew Fioré-Gartland
Katharine J. Bar
Paul Spearman
Mary Allen
Pei-Chun Yu
Bryce A. Manso
Nicole Frahm
Spyros A. Kalams
Lindsey R. Baden
Michael T. Yin
Hyman Scott
Richard M. Novak
Hong‐Van Tieu
Georgia D. Tomaras
James G. Kublin
M. Juliana McElrath
Lawrence Corey
Ian Frank
Artur Olhovetchi Kalichman
Paul T. Edlefsen
Mary E. Enama
John Hural
Renée Holt
Debora Dunbar
David T. Crawford
Ian Maki
Jan N. Johannessen
Scharla Estep
Yevgeny Grigoriev
Tamra Madenwald
Marianne Hansen
Drienna Holman
Ramey Fair
Geneviève Meyer
Anya Luke-Kilolam
Affiliated Authors:
Hong‐Van Tieu
Columbia Affiliation:
Subjects:
AIDS Vaccines (MeSH)
HIV Infections (MeSH)
Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (OpenAlex Topic)
Immunobiology of Dendritic Cells (OpenAlex Topic)
Prediction of Peptide-MHC Binding Affinity (OpenAlex Topic)
Author Keywords:
hiv
fractionated delivery
polytopic vaccination
ad5
epitope breadth
Grants:
UM1AI068635 (NIH – National Institute of Allergy and Infectious Diseases)
P30AI027757 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069534 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069470 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068618 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069554 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069412 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069439 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068614 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069511 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069496 (NIH – National Institute of Allergy and Infectious Diseases)
Publication Type:
Article
Unique ID:
10.1016/j.ebiom.2024.104987
PMID:
38306894
DOI:
10.1016/j.ebiom.2024.104987
Journal:
EBioMedicine
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
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Record Created:

High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials

Reeves, D. B., Mayer, B. T., deCamp, A. C., Huang, Y., Zhang, B., Carpp, L. N., Magaret, C. A., Juraska, M., Gilbert, P. B., Montefiori, D. C., Bar, K. J., Cardozo-Ojeda, E. F., Schiffer, J. T., Rossenkhan, R., Edlefsen, P., Morris, L., Mkhize, N. N., Williamson, C., Mullins, J. I., … Edupuganti, S. (2023). High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-43384-y
Authors:
Daniel B Reeves
Bryan T Mayer
Allan C deCamp
Yunda Huang
Bo Zhang
Lindsay N Carpp
Craig A Magaret
Michal Juraska
Peter B Gilbert
David C Montefiori
Katharine J Bar
E Fabian Cardozo-Ojeda
Joshua T Schiffer
Raabya Rossenkhan
Paul Edlefsen
Lynn Morris
Nonhlanhla N Mkhize
Carolyn Williamson
James I Mullins
Kelly E Seaton
Georgia D Tomaras
Philip Andrew
Nyaradzo Mgodi
Julie E Ledgerwood
Myron S Cohen
Lawrence Corey
Logashvari Naidoo
Catherine Orrell
Paul A Goepfert
Martin Casapia
Magdalena E Sobieszczyk
Shelly T Karuna
Srilatha Edupuganti
Affiliated Authors:
Magdalena E Sobieszczyk
Columbia Affiliation:
Subjects:
HIV Infections (MeSH)
HIV-1 (MeSH)
Grants:
R01AI150500 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068614 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068635 (NIH – National Institute of Allergy and Infectious Diseases)
R37AI054165 (NIH – National Institute of Allergy and Infectious Diseases)
K25AI155224 (NIH – National Institute of Allergy and Infectious Diseases)
P30AI027757 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068613 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068617 (NIH – National Institute of Allergy and Infectious Diseases)
P30AI064518 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068618 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068619 (NIH – National Institute of Allergy and Infectious Diseases)
Publication Type:
Article
Unique ID:
10.1038/s41467-023-43384-y
PMID:
38097552
DOI:
10.1038/s41467-023-43384-y
Journal:
Nature Communications
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created:

Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition

Gilbert, P. B., Huang, Y., deCamp, A. C., Karuna, S., Zhang, Y., Magaret, C. A., Giorgi, E. E., Korber, B., Edlefsen, P. T., Rossenkhan, R., Juraska, M., Rudnicki, E., Kochar, N., Huang, Y., Carpp, L. N., Barouch, D. H., Mkhize, N. N., Hermanus, T., Kgagudi, P., … Morris, L. (2022). Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition. Nature Medicine, 28(9), 1924–1932. https://doi.org/10.1038/s41591-022-01953-6
Authors:
Peter B Gilbert
Yunda Huang
Allan C deCamp
Shelly Karuna
Yuanyuan Zhang
Craig A Magaret
Elena E Giorgi
Bette Korber
Paul T Edlefsen
Raabya Rossenkhan
Michal Juraska
Erika Rudnicki
Nidhi Kochar
Ying Huang
Lindsay N Carpp
Dan H Barouch
Nonhlanhla N Mkhize
Tandile Hermanus
Prudence Kgagudi
Valerie Bekker
Haajira Kaldine
Rutendo E Mapengo
Amanda Eaton
Elize Domin
Carley West
Wenhong Feng
Haili Tang
Kelly E Seaton
Jack Heptinstall
Caroline Brackett
Kelvin Chiong
Georgia D Tomaras
Philip Andrew
Bryan T Mayer
Daniel B Reeves
Magdalena E Sobieszczyk
Nigel Garrett
Jorge Sanchez
Cynthia Gay
Joseph Makhema
Carolyn Williamson
James I Mullins
John Hural
Myron S Cohen
Lawrence Corey
David C Montefiori
Lynn Morris
Affiliated Authors:
Magdalena E Sobieszczyk
Columbia Affiliation:
Subjects:
Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (OpenAlex Topic)
Regulatory T Cell Development and Function (OpenAlex Topic)
Natural Killer Cells in Immunity (OpenAlex Topic)
HIV Infections (MeSH)
HIV-1 (MeSH)
Grants:
P30AI064518 (NIH – National Institute of Allergy and Infectious Diseases)
P01AI131251 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068613 (NIH – National Institute of Allergy and Infectious Diseases)
P30AI027757 (NIH – National Institute of Allergy and Infectious Diseases)
R01AI152115 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068617 (NIH – National Institute of Allergy and Infectious Diseases)
R37AI054165 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068614 (NIH – National Institute of Allergy and Infectious Diseases)
U01AI069470 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068619 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069470 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068618 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068635 (NIH – National Institute of Allergy and Infectious Diseases)
K25AI155224 (NIH – National Institute of Allergy and Infectious Diseases)
Publication Type:
Article
Unique ID:
10.1038/s41591-022-01953-6
PMID:
35995954
DOI:
10.1038/s41591-022-01953-6
Journal:
Nature Medicine
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created:

Correlates of psychological intimate partner violence with HIV care outcomes on patients in HIV care

Fredericksen, R. J., Nance, R. M., Whitney, B. M., Harding, B. N., Fitzsimmons, E., Del Rio, C., Eron, J., Feaster, D. J., Kalokhe, A. S., Mathews, W. C., Mayer, K. H., Metsch, L. R., Mugavero, M. J., Potter, J., O’Cleirigh, C., Napravnik, S., Rodriguez, B., Ruderman, S., JAC, D., & Crane, H. M. (2021). Correlates of psychological intimate partner violence with HIV care outcomes on patients in HIV care. BMC Public Health, 21(1). https://doi.org/10.1186/s12889-021-11854-x
Authors:
R.J. Fredericksen
R.M. Nance
B.M. Whitney
B.N. Harding
E. Fitzsimmons
C. Del Rio
J. Eron
D.J. Feaster
A.S. Kalokhe
W.C. Mathews
K.H. Mayer
L.R. Metsch
M.J. Mugavero
J. Potter
C. O’Cleirigh
S. Napravnik
B. Rodriguez
S. Ruderman
Delaney Jac
H.M. Crane
Affiliated Authors:
L.R. Metsch
Columbia Affiliation:
Author Keywords:
hiv care
patient reported outcomes
psychological violence
Grants:
P30AI027767 (NIH – National Institute of Allergy and Infectious Diseases)
P30AI027757 (NIH – National Institute of Allergy and Infectious Diseases)
R24AI067039 (NIH – National Institute of Allergy and Infectious Diseases)
U01DA037702 (NIH – National Institute On Drug Abuse)
R01DA032098 (NIH – National Institute On Drug Abuse)
R01DA035280 (NIH – National Institute On Drug Abuse)
Publication Type:
Article
Unique ID:
10.1186/s12889-021-11854-x
PMID:
34627181
DOI:
10.1186/s12889-021-11854-x
Journal:
BMC Public Health
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record

Record Created:

Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis

Nickolas, T. L., Barasch, J., Mugwanya, K. K., Branch, A. D., Heffron, R., Wanga, V., Mugo, N. R., Ronald, A., Celum, C., Donnell, D., Baeten, J. M., & Wyatt, C. M. (2021). Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis. AIDS, 35(7), 1147–1149. https://doi.org/10.1097/qad.0000000000002865
Authors:
Thomas L. Nickolas
Jonathan Barasch
Kenneth K. Mugwanya
Andrea D. Branch
Renee Heffron
Valentine Wanga
Nelly R. Mugo
Allan Ronald
Connie Celum
Deborah Donnell
Jared M. Baeten
Christina M. Wyatt
Affiliated Authors:
Thomas L. Nickolas
Jonathan Barasch
Columbia Affiliation:
Subjects:
Prevention and Treatment of HIV/AIDS Infection (OpenAlex Topic)
Efficacy and Safety of Antiretroviral Therapy for HIV (OpenAlex Topic)
Impact of HIV Infection on Cardiovascular Health (OpenAlex Topic)
Anti-HIV Agents (MeSH)
HIV Infections (MeSH)
Pre-Exposure Prophylaxis (MeSH)
Grants:
R01HD089843 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
P30AI027757 (NIH – National Institute of Allergy and Infectious Diseases)
R01DK112258 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK100272 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1097/QAD.0000000000002865
PMID:
33710023
DOI:
10.1097/QAD.0000000000002865
Journal:
AIDS
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View OpenAlex Record

Record Created:

Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition

Corey, L., Gilbert, P. B., Juraska, M., Montefiori, D. C., Morris, L., Karuna, S. T., Edupuganti, S., Mgodi, N. M., deCamp, A. C., Rudnicki, E., Huang, Y., Gonzales, P., Cabello, R., Orrell, C., Lama, J. R., Laher, F., Lazarus, E. M., Sanchez, J., Frank, I., … Cohen, M. S. (2021). Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition. New England Journal of Medicine, 384(11), 1003–1014. https://doi.org/10.1056/nejmoa2031738
Authors:
Lawrence Corey
Peter B Gilbert
Michal Juraska
David C Montefiori
Lynn Morris
Shelly T Karuna
Srilatha Edupuganti
Nyaradzo M Mgodi
Allan C deCamp
Erika Rudnicki
Yunda Huang
Pedro Gonzales
Robinson Cabello
Catherine Orrell
Javier R Lama
Fatima Laher
Erica M Lazarus
Jorge Sanchez
Ian Frank
Juan Hinojosa
Magdalena E Sobieszczyk
Kyle E Marshall
Pamela G Mukwekwerere
Joseph Makhema
Lindsey R Baden
James I Mullins
Carolyn Williamson
John Hural
M Juliana McElrath
Carter Bentley
Simbarashe Takuva
Margarita M Gomez Lorenzo
David N Burns
Nicole Espy
April K Randhawa
Nidhi Kochar
Estelle Piwowar-Manning
Deborah J Donnell
Nirupama Sista
Philip Andrew
James G Kublin
Glenda Gray
Julie E Ledgerwood
John R Mascola
Myron S Cohen
Affiliated Authors:
Lawrence Corey
Peter B Gilbert
Michal Juraska
David C Montefiori
Lynn Morris
Shelly T Karuna
Srilatha Edupuganti
Nyaradzo M Mgodi
Allan C deCamp
Erika Rudnicki
Yunda Huang
Pedro Gonzales
Robinson Cabello
Catherine Orrell
Javier R Lama
Fatima Laher
Erica M Lazarus
Jorge Sanchez
Ian Frank
Juan Hinojosa
Magdalena E Sobieszczyk
Kyle E Marshall
Pamela G Mukwekwerere
Joseph Makhema
Lindsey R Baden
James I Mullins
Carolyn Williamson
John Hural
M Juliana McElrath
Carter Bentley
Simbarashe Takuva
Margarita M Gomez Lorenzo
David N Burns
Nicole Espy
April K Randhawa
Nidhi Kochar
Estelle Piwowar-Manning
Deborah J Donnell
Nirupama Sista
Philip Andrew
James G Kublin
Glenda Gray
Julie E Ledgerwood
John R Mascola
Myron S Cohen
Columbia Affiliation:
Subjects:
Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (OpenAlex Topic)
Efficacy and Safety of Antiretroviral Therapy for HIV (OpenAlex Topic)
Prevention and Treatment of HIV/AIDS Infection (OpenAlex Topic)
Antibodies, Monoclonal (MeSH)
Broadly Neutralizing Antibodies (MeSH)
HIV Antibodies (MeSH)
HIV Infections (MeSH)
HIV-1 (MeSH)
Grants:
UM1AI068635 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI154468 (NIH – National Institute of Allergy and Infectious Diseases)
P30AI027757 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068618 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068619 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069481 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069470 (NIH – National Institute of Allergy and Infectious Diseases)
ZIAAI005048 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068617 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069412 (NIH – National Institute of Allergy and Infectious Diseases)
P30AI045008 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069463 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069424 (NIH – National Institute of Allergy and Infectious Diseases)
U01AI069476 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069436 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069469 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068613 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI068614 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI108568 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069496 (NIH – National Institute of Allergy and Infectious Diseases)
U01AI069436 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069476 (NIH – National Institute of Allergy and Infectious Diseases)
UM1AI069453 (NIH – National Institute of Allergy and Infectious Diseases)
Publication Type:
Article
Unique ID:
10.1056/nejmoa2031738
PMID:
33730454
DOI:
10.1056/nejmoa2031738
Journal:
New England Journal of Medicine
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record
View OpenAlex Record
View Scopus Record

Record Created:

Increasing Heroin-Methamphetamine (Goofball) Use and Related Morbidity Among Seattle Area People Who Inject Drugs

Glick, S. N., Klein, K. S., Tinsley, J., & Golden, M. R. (2020). Increasing Heroin‐Methamphetamine (Goofball) Use and Related Morbidity Among Seattle Area People Who Inject Drugs. The American Journal on Addictions, 30(2), 183–191. Portico. https://doi.org/10.1111/ajad.13115
Authors:
Sara N. Glick
Kathryn S. Klein
Joe Tinsley
Matthew R. Golden
Affiliated Authors:
Kathryn S. Klein
Columbia Affiliation:
Grants:
UL1TR002319 (NIH – National Center for Advancing Translational Sciences)
P30AI027757 (NIH – National Institute of Allergy and Infectious Diseases)
Publication Type:
Article
Unique ID:
10.1111/ajad.13115
PMID:
33301230
DOI:
10.1111/ajad.13115
Journal:
American Journal on Addictions
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record

Record Created:

CSV