Natural Killer Cells in Immunity

Displaying 1 - 50 of 86CSV
Bosticardo, M., Dobbs, K., Delmonte, O. M., Martins, A. J., Pala, F., Kawai, T., Kenney, H., Magro, G., Rosen, L. B., Yamazaki, Y., Yu, H.-H., Calzoni, E., Lee, Y. N., Liu, C., Stoddard, J., Niemela, J., Fink, D., Castagnoli, R., Ramba, M., … Gentile, N. (2025). Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature. Science Immunology, 10(103). https://doi.org/10.1126/sciimmunol.adq1697
Publication Date
Diehl, C., Soberón, V., Baygün, S., Chu, Y., Mandelbaum, J., Kraus, L., Engleitner, T., Rudelius, M., Fangazio, M., Daniel, C., Bortoluzzi, S., Helmrath, S., Singroul, P., Gölling, V., Osorio Barrios, F., Seyhan, G., Oßwald, L., Kober-Hasslacher, M., Zeng, T., … Schmidt-Supprian, M. (2024). Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis. Immunity. https://doi.org/10.1016/j.immuni.2024.11.023
Publication Date
Hertel, A., Aguiar, T., Mashiko, S., Núñez, S., Moore, C., Gao, B., Ausmeier, M., Roy, P., & Zorn, E. (2024). Clones reactive to apoptotic cells and specific chemical adducts are prevalent among human thymic B cells. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1462126
Publication Date
Hao, L. Y., Lerrer, S., Paiola, M., Moore, E. K., Gartshteyn, Y., Song, R., Goeckeritz, M., Black, M. J., Bukhari, S., Hu, X., & Mor, A. (2024). Exclusion of PD-1 from the immune synapse: A novel strategy to modulate T cell function. Molecular Therapy: Oncology, 32(3), 200839. https://doi.org/10.1016/j.omton.2024.200839
Publication Date
Chandrakasan, S., Allen, C. E., Bhatla, D., Carter, J., Chien, M., Cooper, R., Draper, L., Eckstein, O. S., Hanna, R., Hays, J. A., Hermiston, M. L., Hinson, A. P., Hobday, P. M., Isakoff, M. S., Jordan, M. B., Leiding, J. W., Modica, R., Nakano, T. A., … Oladapo, A. (2024). Emapalumab Treatment in Patients With Rheumatologic Disease–Associated Hemophagocytic Lymphohistiocytosis in the United States: A Retrospective Medical Chart Review Study. Arthritis & Rheumatology. Portico. https://doi.org/10.1002/art.42985
Publication Date
Bullock, M. E., Hogan, T., Williams, C., Morris, S., Nowicka, M., Sharjeel, M., van Dorp, C., Yates, A. J., & Seddon, B. (2024). The dynamics and longevity of circulating CD4+ memory T cells depend on cell age and not the chronological age of the host. PLOS Biology, 22(8), e3002380. https://doi.org/10.1371/journal.pbio.3002380
Publication Date
DeFilipp, Z., Kim, H. T., Spyrou, N., Katsivelos, N., Kowalyk, S., Eng, G., Kasikis, S., Beheshti, R., Baez, J., Akahoshi, Y., Ayuk, F., Choe, H., Etra, A., Grupp, S. A., Hexner, E. O., Hogan, W. J., Kitko, C. L., Qayed, M., Reshef, R., … Chen, Y.-B. (2024). The MAGIC algorithm probability predicts treatment response and long-term outcomes to second-line therapy for acute GVHD. Blood Advances, 8(13), 3488–3496. https://doi.org/10.1182/bloodadvances.2024012561
Publication Date
Nguyen, T. T. T., Gao, Q., Mun, J.-Y., Zhu, Z., Shu, C., Naim, A., Rogava, M., Izar, B., Westhoff, M.-A., Karpel-Massler, G., & Siegelin, M. D. (2024). Suppressing PD-L1 Expression via AURKA Kinase Inhibition Enhances Natural Killer Cell-Mediated Cytotoxicity against Glioblastoma. Cells, 13(13), 1155. https://doi.org/10.3390/cells13131155
Publication Date
Firdessa-Fite, R., Johnson, S. N., Bechi Genzano, C., Leon, M. A., Ku, A., Ocampo Gonzalez, F. A., Milner, J. D., Sestak, J. O., Berkland, C., & Creusot, R. J. (2024). Soluble antigen arrays provide increased efficacy and safety over free peptides for tolerogenic immunotherapy. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1258369
Publication Date
Yu, H., Nishio, H., Barbi, J., Mitchell-Flack, M., Vignali, P. D., Zheng, Y., Lebid, A., Chang, K.-Y., Fu, J., Higgins, M., Huang, C.-T., Zhang, X., Li, Z., Blosser, L., Tam, A., Drake, C., & Pardoll, D. (2024). Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity. ELife, 13. CLOCKSS. https://doi.org/10.7554/elife.96812
Publication Date
Gray, J. I., Caron, D. P., Wells, S. B., Guyer, R., Szabo, P., Rainbow, D., Ergen, C., Rybkina, K., Bradley, M. C., Matsumoto, R., Pethe, K., Kubota, M., Teichmann, S., Jones, J., Yosef, N., Atkinson, M., Brusko, M., Brusko, T. M., Connors, T. J., … Farber, D. L. (2024). Human γδ T cells in diverse tissues exhibit site-specific maturation dynamics across the life span. Science Immunology, 9(96). https://doi.org/10.1126/sciimmunol.adn3954
Publication Date
Randolph, H. E., Aracena, K. A., Lin, Y., Mu, Z., & Barreiro, L. B. (2024). Shaping immunity: The influence of natural selection on population immune diversity. Immunological Reviews, 323(1), 227–240. Portico. https://doi.org/10.1111/imr.13329
Publication Date
Benavente, M. C. R., Hakeem, Z. A., Davis, A. R., Murray, N. B., Azadi, P., Mace, E. M., & Barb, A. W. (2024). Distinct CD16a features on human NK cells observed by flow cytometry correlate with increased ADCC. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-58541-6
Publication Date
Gartshteyn, Y., Geraldino-Pardilla, L., Khalili, L., Bukhari, S., Lerrer, S., Winchester, R. J., Askanase, A. D., & Mor, A. (2024). SAP-expressing T peripheral helper cells identify systemic lupus erythematosus patients with lupus nephritis. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1327437
Publication Date
Philips, E. A., Liu, J., Kvalvaag, A., Mørch, A. M., Tocheva, A. S., Ng, C., Liang, H., Ahearn, I. M., Pan, R., Luo, C. C., Leithner, A., Qin, Z., Zhou, Y., Garcia-España, A., Mor, A., Littman, D. R., Dustin, M. L., Wang, J., & Kong, X.-P. (2024). Transmembrane domain–driven PD-1 dimers mediate T cell inhibition. Science Immunology, 9(93). https://doi.org/10.1126/sciimmunol.ade6256
Publication Date
Babushku, T., Lechner, M., Ehrenberg, S., Rambold, U., Schmidt-Supprian, M., Yates, A. J., Rane, S., Zimber-Strobl, U., & Strobl, L. J. (2024). Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-46024-1
Publication Date
Tenggara, M. K., Oh, S.-H., Yang, C., Nariya, H. K., Metz, A. M., Upadhyay, A. A., Gudipati, D. R., Guo, L., McGhee, E. G., Gill, K., Viox, E. G., Mason, R. D., Doria-Rose, N. A., Foulds, K. E., Mascola, J. R., Du, Y., Fu, H., Altman, J. D., Yan, Q., … Kong, R. (2024). Frequency-potency analysis of IgG+ memory B cells delineates neutralizing antibody responses at single-cell resolution. Cell Reports, 43(3), 113948. https://doi.org/10.1016/j.celrep.2024.113948
Publication Date
Zorko, N. A., Makovec, A., Elliott, A., Kellen, S., Lozada, J. R., Arafa, A. T., Felices, M., Shackelford, M., Barata, P., Zakharia, Y., Narayan, V., Stein, M. N., Zarrabi, K. K., Patniak, A., Bilen, M. A., Radovich, M., Sledge, G., El-Deiry, W. S., Heath, E. I., … Antonarakis, E. S. (2024). Natural Killer Cell Infiltration in Prostate Cancers Predict Improved Patient Outcomes. Prostate Cancer and Prostatic Diseases. https://doi.org/10.1038/s41391-024-00797-0
Publication Date
Weber, S., Menees, K. B., Park, J., Agin-Liebes, J., Lin, C.-C., Alcalay, R. N., & Lee, J.-K. (2024). Distinctive CD56dim NK subset profiles and increased NKG2D expression in blood NK cells of Parkinson’s disease patients. Npj Parkinson’s Disease, 10(1). https://doi.org/10.1038/s41531-024-00652-y
Publication Date
Neelapu, S. S., Chavez, J. C., Sehgal, A. R., Epperla, N., Ulrickson, M., Bachy, E., Munshi, P. N., Casulo, C., Maloney, D. G., de Vos, S., Reshef, R., Leslie, L. A., Oluwole, O. O., Yakoub-Agha, I., Khanal, R., Rosenblatt, J., Korn, R., Peng, W., Lui, C., … Jacobson, C. A. (2024). Three-year follow-up analysis of axicabtagene ciloleucel in relapsed/refractory indolent non-Hodgkin lymphoma (ZUMA-5). Blood, 143(6), 496–506. https://doi.org/10.1182/blood.2023021243
Publication Date
Straube, J., Bukhari, S., Lerrer, S., Winchester, R. J., Gartshteyn, Y., Henick, B. S., Dragovich, M. A., & Mor, A. (2024). PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis. Arthritis Research & Therapy, 26(1). https://doi.org/10.1186/s13075-023-03259-5
Publication Date
Borna, Š., Lee, E., Nideffer, J., Ramachandran, A., Wang, B., Baker, J., Mavers, M., Lakshmanan, U., Narula, M., Garrett, A. K., Schulze, J., Olek, S., Marois, L., Gernez, Y., Bhatia, M., Chong, H. J., Walter, J., Kitcharoensakkul, M., Lang, A., … Bacchetta, R. (2023). Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations. Science Translational Medicine, 15(727). https://doi.org/10.1126/scitranslmed.adg6822
Publication Date
Van, N. T., Zhang, K., Wigmore, R. M., Kennedy, A. I., DaSilva, C. R., Huang, J., Ambelil, M., Villagomez, J. H., O’Connor, G. J., Longman, R. S., Cao, M., Snook, A. E., Platten, M., Kasenty, G., Sigal, L. J., Prendergast, G. C., & Kim, S. V. (2023). Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-43211-4
Publication Date
Tsuji, M., Nair, M. S., Masuda, K., Castagna, C., Chong, Z., Darling, T. L., Seehra, K., Hwang, Y., Ribeiro, Á. L., Ferreira, G. M., Corredor, L., Coelho-dos-Reis, J. G. A., Tsuji, Y., Mori, M., Boon, A. C. M., Diamond, M. S., Huang, Y., & Ho, D. D. (2023). An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39738-1
Publication Date
Le Voyer, T., Parent, A. V., Liu, X., Cederholm, A., Gervais, A., Rosain, J., Nguyen, T., Perez Lorenzo, M., Rackaityte, E., Rinchai, D., Zhang, P., Bizien, L., Hancioglu, G., Ghillani-Dalbin, P., Charuel, J.-L., Philippot, Q., Gueye, M. S., Maglorius Renkilaraj, M. R. L., … Ogishi, M. (2023). Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency. Nature, 623(7988), 803–813. https://doi.org/10.1038/s41586-023-06717-x
Publication Date
Wang, X. K., Uzuni, A., Belay, K., Harle, D. W., Gordillo, C. A., Macedo, R. J., Chakrabarti, S., Shi, L., Pressler, M., Fuller, J., Azizi, E., & Reshef, R. (2023). Characteristics of Alloreactive T-Cell Clones That Predict Early Development of Acute GvHD Following Allogeneic HCT. Blood, 142(Supplement 1), 2042–2042. https://doi.org/10.1182/blood-2023-187932
Publication Date
Piorczynski, T. B., Ryu, Y. K., Pazos, M., Huang, W., Tolu, S. S., Estrella, B., & Amengual, J. E. (2023). Combination Epigenetic Therapy Using YF2, a First-in-Class Histone Acetyltransferase Activator, Restores Immunogenicity in Diffuse Large B-Cell Lymphoma. Blood, 142(Supplement 1), 4391–4391. https://doi.org/10.1182/blood-2023-179271
Publication Date
Sellyei, J., Yan, X., Qiu, W., Vasilescu, E., & Vlad, G. (2023). A novel HLA‐B*58:141 allele identified by next‐generation sequencing in a potential hematopoietic cell recipient. HLA, 103(1). Portico. https://doi.org/10.1111/tan.15237
Publication Date
Berton, R. R., McGonagil, P. W., Jensen, I. J., Ybarra, T. K., Bishop, G. A., Harty, J. T., Griffith, T. S., & Badovinac, V. P. (2023). Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells. PLOS Pathogens, 19(10), e1011720. https://doi.org/10.1371/journal.ppat.1011720
Publication Date
Parikh, A. S., Li, Y., Mazul, A., Yu, V. X., Thorstad, W., Rich, J., Paniello, R. C., Caruana, S. M., Troob, S. H., Jackson, R. S., Pipkorn, P., Zolkind, P., Qi, Z., Adkins, D., Ding, L., & Puram, S. V. (2023). Immune Cell Deconvolution Reveals Possible Association of γδ T Cells with Poor Survival in Head and Neck Squamous Cell Carcinoma. Cancers, 15(19), 4855. https://doi.org/10.3390/cancers15194855
Publication Date
Jash, A., Hay, A., Keele, G., Churchill, G., Hudson, K., & Zimring, J. (2023). OA2‐AM23‐MN‐19 | Genetic Loci Containing Immunoregulatory IFIT Genes are Associated with RBC Alloimmunization in an Outbred Mouse Population. Transfusion, 63(S5). Portico. https://doi.org/10.1111/trf.45_17554
Publication Date
Zotti, F. D., Qiu, A., Miller, A., Zimring, J., & Hudson, K. (2023). PL2‐AM23‐SN‐30 | Apyrase Reduces Severity of Autoimmune Hemolytic Anemia (AIHA) Secondary to Checkpoint Inhibitors in a Mouse Model. Transfusion, 63(S5). Portico. https://doi.org/10.1111/trf.1_17554
Publication Date
Al Malki, M. M., London, K., Baez, J., Akahoshi, Y., Hogan, W. J., Etra, A., Choe, H., Hexner, E., Langston, A., Abhyankar, S., Ponce, D. M., DeFilipp, Z., Kitko, C. L., Adekola, K., Reshef, R., Ayuk, F., Capellini, A., Chanswangphuwana, C., Eder, M., … Levine, J. E. (2023). Phase 2 study of natalizumab plus standard corticosteroid treatment for high-risk acute graft-versus-host disease. Blood Advances, 7(17), 5189–5198. https://doi.org/10.1182/bloodadvances.2023009853
Publication Date
Qin, Y., Mace, E. M., & Barton, J. P. (2023). An inference model gives insights into innate immune adaptation and repertoire diversity. Proceedings of the National Academy of Sciences, 120(38). https://doi.org/10.1073/pnas.2305859120
Publication Date
Connors, T. J., Matsumoto, R., Verma, S., Szabo, P. A., Guyer, R., Gray, J., Wang, Z., Thapa, P., Dogra, P., Poon, M. M. L., Rybkina, K., Bradley, M. C., Idzikowski, E., McNichols, J., Kubota, M., Pethe, K., Shen, Y., Atkinson, M. A., Brusko, M., … Farber, D. L. (2023). Site-specific development and progressive maturation of human tissue-resident memory T cells over infancy and childhood. Immunity, 56(8), 1894-1909.e5. https://doi.org/10.1016/j.immuni.2023.06.008
Publication Date
Brownlie, R. J., Kennedy, R., Wilson, E. B., Milanovic, M., Taylor, C. F., Wang, D., Davies, J. R., Owston, H., Adams, E. J., Stephenson, S., Caeser, R., Gewurz, B. E., Giannoudis, P. V., Scuoppo, C., McGonagle, D., Hodson, D. J., Tooze, R. M., Doody, G. M., Cook, G., … Klein, U. (2023). Cytokine receptor IL27RA is an NF-κB–responsive gene involved in CD38 upregulation in multiple myeloma. Blood Advances, 7(15), 3874–3890. https://doi.org/10.1182/bloodadvances.2022009044
Publication Date
Columbia Affiliation
Lukas, E., Hogan, T., Williams, C., Seddon, B., & Yates, A. J. (2023). Quantifying cellular dynamics in mice using a novel fluorescent division reporter system. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1157705
Publication Date
Lee, E. Y., Dai, Z., Jaiswal, A., Wang, E. H. C., Anandasabapathy, N., & Christiano, A. M. (2023). Functional interrogation of lymphocyte subsets in alopecia areata using single-cell RNA sequencing. Proceedings of the National Academy of Sciences, 120(29). https://doi.org/10.1073/pnas.2305764120
Publication Date
Ali, A. M., BenMohamed, F., Decina, A., Mukherjee, S., Levi, S., Garrido Castillo, L. N., Bréchot, D., Jurcic, J., Raza, A., & Paterlini Bréchot, P. (2023). Circulating cancer giant cells with unique characteristics frequently found in patients with myelodysplastic syndromes (MDS). Medical Oncology, 40(7). https://doi.org/10.1007/s12032-023-02064-z
Publication Date
McNerney, K. O., Si Lim, S. J., Ishikawa, K., Dreyzin, A., Vatsayan, A., Chen, J. J., Baggott, C., Prabhu, S., Pacenta, H. L., Philips, C., Rossoff, J., Stefanski, H. E., Talano, J.-A., Moskop, A., Verneris, M., Myers, D., Karras, N. A., Brown, P., Bonifant, C. L., … Schultz, L. M. (2023). HLH-like toxicities predict poor survival after the use of tisagenlecleucel in children and young adults with B-ALL. Blood Advances, 7(12), 2758–2771. https://doi.org/10.1182/bloodadvances.2022008893
Publication Date
Long, K. D., & Fu, J. (2023). Chimerism and phenotypic analysis of intraepithelial and lamina propria T cells isolated from human ileal biopsies after intestinal transplantation. STAR Protocols, 4(2), 102192. https://doi.org/10.1016/j.xpro.2023.102192
Publication Date
Kim, W. S., Shortt, J., Zinzani, P. L., Mikhaylova, N., Marin‐Niebla, A., Radeski, D., Ribrag, V., Domenech, E. D., Sawas, A., Alexis, K., Emig, M., Garcia, L., Overesch, A., Pietzko, K., & Horwitz, S. (2023). AFM13 IN PATIENTS WITH CD30 POSITIVE RELAPSED OR REFRACTORY (R/R) PERIPHERAL T CELL LYMPHOMA (PTCL): RESULTS FROM THE PHASE 2 REDIRECT STUDY. Hematological Oncology, 41(S2), 195–196. Portico. https://doi.org/10.1002/hon.3163_126
Publication Date
Rancan, C., Arias-Badia, M., Dogra, P., Chen, B., Aran, D., Yang, H., Luong, D., Ilano, A., Li, J., Chang, H., Kwek, S. S., Zhang, L., Lanier, L. L., Meng, M. V., Farber, D. L., & Fong, L. (2023). Exhausted intratumoral Vδ2− γδ T cells in human kidney cancer retain effector function. Nature Immunology, 24(4), 612–624. https://doi.org/10.1038/s41590-023-01448-7
Publication Date
Siddiqui, B. A., Chapin, B. F., Jindal, S., Duan, F., Basu, S., Yadav, S. S., Gu, A.-D., Espejo, A. B., Kinder, M., Pettaway, C. A., Ward, J. F., Tidwell, R. S. S., Troncoso, P., Corn, P. G., Logothetis, C. J., Knoblauch, R., Hutnick, N., Gottardis, M., Drake, C. G., … Subudhi, S. K. (2023). Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor). Journal for ImmunoTherapy of Cancer, 11(3), e006262. https://doi.org/10.1136/jitc-2022-006262
Publication Date