Chang, L.-C., Yin, M. T., Laird, G. M., Ritter, K. D., Shah, J. G., & Debnath, A. K. (2025). A First-in-Class Dual Degrader of Bcl-2/Bcl-xL Reverses HIV Latency and Minimizes Ex Vivo Reservoirs from Patients. International Journal of Molecular Sciences, 26(6), 2772. https://doi.org/10.3390/ijms26062772

Mason, R. D., Zhang, B., Morano, N. C., Shen, C.-H., McKee, K., Heimann, A., Du, R., Nazzari, A. F., Hodges, S., Kanai, T., Lin, B. C., Louder, M. K., Doria-Rose, N. A., Zhou, T., Shapiro, L., Roederer, M., Kwong, P. D., & Gorman, J. (2025). Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage. Cell Reports, 44(1), 115223. https://doi.org/10.1016/j.celrep.2024.115223

Cale, E. M., Shen, C.-H., Olia, A. S., Radakovich, N. A., Rawi, R., Yang, Y., Ambrozak, D. R., Bennici, A. K., Chuang, G.-Y., Crooks, E. D., Driscoll, J. I., Lin, B. C., Louder, M. K., Madden, P. J., Messina, M. A., Osawa, K., Stewart-Jones, G. B. E., Verardi, R., Vrakas, Z., … Gorman, J. (2024). A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies. Cell Reports, 43(12), 115010. https://doi.org/10.1016/j.celrep.2024.115010

Reveiz, M., Xu, K., Lee, M., Wang, S., Olia, A. S., Harris, D. R., Liu, K., Liu, T., Schaub, A. J., Stephens, T., Wang, Y., Zhang, B., Huang, R., Tsybovsky, Y., Kwong, P. D., & Rawi, R. (2024). Vaccine-elicited and naturally elicited antibodies differ in their recognition of the HIV-1 fusion peptide. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1484029

Xu, J., Zhou, T., McKee, K., Zhang, B., Liu, C., Nazzari, A. F., Pegu, A., Shen, C., Becker, J. E., Bender, M. F., Chan, P., Changela, A., Chaudhary, R., Chen, X., Einav, T., Kwon, Y. D., Lin, B. C., Louder, M. K., Merriam, J. S., … Kwong, P. D. (2024). Ultrapotent Broadly Neutralizing Human‐llama Bispecific Antibodies against HIV‐1. Advanced Science, 11(26). Portico. https://doi.org/10.1002/advs.202309268

Prakash, P., Khodke, P., Balasubramaniam, M., Davids, B.-O., Hollis, T., Davis, J., Kumbhar, B., & Dash, C. (2024). Three prime repair exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural, and conformational properties. Journal of Biological Chemistry, 300(7), 107438. https://doi.org/10.1016/j.jbc.2024.107438

Tenggara, M. K., Oh, S.-H., Yang, C., Nariya, H. K., Metz, A. M., Upadhyay, A. A., Gudipati, D. R., Guo, L., McGhee, E. G., Gill, K., Viox, E. G., Mason, R. D., Doria-Rose, N. A., Foulds, K. E., Mascola, J. R., Du, Y., Fu, H., Altman, J. D., Yan, Q., … Kong, R. (2024). Frequency-potency analysis of IgG+ memory B cells delineates neutralizing antibody responses at single-cell resolution. Cell Reports, 43(3), 113948. https://doi.org/10.1016/j.celrep.2024.113948

Joseph, S. B., Abrahams, M.-R., Moeser, M., Tyers, L., Archin, N. M., Council, O. D., Sondgeroth, A., Spielvogel, E., Emery, A., Zhou, S., Doolabh, D., Ismail, S. D., Karim, S. A., Margolis, D. M., Pond, S. K., Garrett, N., Swanstrom, R., & Williamson, C. (2024). The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus. PLOS Pathogens, 20(2), e1011974. https://doi.org/10.1371/journal.ppat.1011974

Shalekoff, S., Dias, B. D. C., Loubser, S., Strehlau, R., Kuhn, L., & Tiemessen, C. T. (2024). Higher CCR5 density on CD4+ T-cells in mothers and infants is associated with increased risk of in-utero HIV-1 transmission. AIDS, 38(7), 945–954. https://doi.org/10.1097/qad.0000000000003857

Reeves, D. B., Mayer, B. T., deCamp, A. C., Huang, Y., Zhang, B., Carpp, L. N., Magaret, C. A., Juraska, M., Gilbert, P. B., Montefiori, D. C., Bar, K. J., Cardozo-Ojeda, E. F., Schiffer, J. T., Rossenkhan, R., Edlefsen, P., Morris, L., Mkhize, N. N., Williamson, C., Mullins, J. I., … Edupuganti, S. (2023). High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-43384-y

Singh, Y., Castillo-Mancilla, J., Madimabe, R., Jennings, L., Ferraris, C. M., Robbins, R. N., Anderson, P. L., Remien, R. H., & Orrell, C. (2023). Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa. AIDS Research and Therapy, 20(1). https://doi.org/10.1186/s12981-023-00552-w

Matassoli, F., Cagigi, A., Shen, C.-H., Henry, A. R., Johnston, T. S., Schramm, C. A., Cottrell, C. A., Kalyuzhniy, O., Spangler, A., Ndung’u, T., Dong, K., Eller, L., Robb, M., Eller, M., Naluyima, P., Kwong, P. D., Douek, D. C., Schief, W. R., Andrews, S. F., & McDermott, A. B. (2023). High frequency of HIV precursor-target-specific B cells in sub-Saharan populations. Cell Reports, 42(12), 113450. https://doi.org/10.1016/j.celrep.2023.113450

Sobieszczyk, M. E., Mannheimer, S., Paez, C. A., Yu, C., Gamble, T., Theodore, D. A., Chege, W., Yacovone, M., Hanscom, B., Heptinstall, J., Seaton, K. E., Zhang, L., Miner, M. D., Eaton, A., Weiner, J. A., Mayer, K., Kalams, S., Stephenson, K., Julg, B., … Montefiori, D. (2023). Safety, tolerability, pharmacokinetics, and immunological activity of dual-combinations and triple-combinations of anti-HIV monoclonal antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS administered intravenously to HIV-uninfected adults: a phase 1 randomised trial. The Lancet HIV, 10(10), e653–e662. https://doi.org/10.1016/s2352-3018(23)00140-6

Schulz, V. E., Tuff, J. F., Tough, R. H., Lewis, L., Chimukangara, B., Garrett, N., Abdool Karim, Q., Abdool Karim, S. S., McKinnon, L. R., Kharsany, A. B. M., & McLaren, P. J. (2023). Host genetic variation at a locus near CHD1L impacts HIV sequence diversity in a South African population. Journal of Virology, 97(10). https://doi.org/10.1128/jvi.00954-23

Glögl, M., Friedrich, N., Cerutti, G., Lemmin, T., Kwon, Y. D., Gorman, J., Maliqi, L., Mittl, P. R. E., Hesselman, M. C., Schmidt, D., Weber, J., Foulkes, C., Dingens, A. S., Bylund, T., Olia, A. S., Verardi, R., Reinberg, T., Baumann, N. S., Rusert, P., … Trkola, A. (2023). Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nature Structural & Molecular Biology, 30(9), 1323–1336. https://doi.org/10.1038/s41594-023-01062-z

McLaren, P. J., Porreca, I., Iaconis, G., Mok, H. P., Mukhopadhyay, S., Karakoc, E., Cristinelli, S., Pomilla, C., Bartha, I., Thorball, C. W., Tough, R. H., Angelino, P., Kiar, C. S., Carstensen, T., Fatumo, S., Porter, T., Jarvis, I., Skarnes, W. C., Bassett, A., … Fellay, J. (2023). Africa-specific human genetic variation near CHD1L associates with HIV-1 load. Nature, 620(7976), 1025–1030. https://doi.org/10.1038/s41586-023-06370-4

Wang, S., Matassoli, F., Zhang, B., Liu, T., Shen, C.-H., Bylund, T., Johnston, T., Henry, A. R., Teng, I.-T., Tripathi, P., Becker, J. E., Changela, A., Chaudhary, R., Cheng, C., Gaudinski, M., Gorman, J., Harris, D. R., Lee, M., Morano, N. C., … Kwong, P. D. (2023). HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide. Cell Reports, 42(7), 112755. https://doi.org/10.1016/j.celrep.2023.112755

Xu, Y., Ferguson, T., Masuda, K., Siddiqui, M. A., Smith, K. P., Vest, O., Brooks, B., Zhou, Z., Obliosca, J., Kong, X.-P., Jiang, X., Yamashita, M., Moriya, T., & Tison, C. (2023). Short Carbon Nanotube-Based Delivery of mRNA for HIV-1 Vaccines. Biomolecules, 13(7), 1088. https://doi.org/10.3390/biom13071088

Ken, M. L., Roy, R., Geng, A., Ganser, L. R., Manghrani, A., Cullen, B. R., Schulze-Gahmen, U., Herschlag, D., & Al-Hashimi, H. M. (2023). RNA conformational propensities determine cellular activity. Nature, 617(7962), 835–841. https://doi.org/10.1038/s41586-023-06080-x

Fritschi, C. J., Anang, S., Gong, Z., Mohammadi, M., Richard, J., Bourassa, C., Severino, K. T., Richter, H., Yang, D., Chen, H.-C., Chiu, T.-J., Seaman, M. S., Madani, N., Abrams, C., Finzi, A., Hendrickson, W. A., Sodroski, J. G., & Smith, A. B. (2023). Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity. Proceedings of the National Academy of Sciences, 120(13). https://doi.org/10.1073/pnas.2222073120

Rosenberg, N. E., Shook-Sa, B. E., Liu, M., Stranix-Chibanda, L., Yotebieng, M., Sam-Agudu, N. A., Hudgens, M. G., Phiri, S. J., Mutale, W., Bekker, L.-G., Moyo, S., Zuma, K., Charurat, M. E., Justman, J., & Chi, B. H. (2023). Adult HIV-1 incidence across 15 high-burden countries in sub-Saharan Africa from 2015 to 2019: a pooled analysis of nationally representative data. The Lancet HIV, 10(3), e175–e185. https://doi.org/10.1016/s2352-3018(22)00328-9

Jin, D., Zhu, Y., Schubert, H. L., Goff, S. P., & Musier-Forsyth, K. (2023). HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit. Viruses, 15(2), 474. https://doi.org/10.3390/v15020474

Karim, Q. A., Archary, D., Barré-Sinoussi, F., Broliden, K., Cabrera, C., Chiodi, F., Fidler, S. J., Gengiah, T. N., Herrera, C., Kharsany, A. B. M., Liebenberg, L. J. P., Mahomed, S., Menu, E., Moog, C., Scarlatti, G., Seddiki, N., Sivro, A., & Cavarelli, M. (2022). Women for science and science for women: Gaps, challenges and opportunities towards optimizing pre-exposure prophylaxis for HIV-1 prevention. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.1055042

Geis, F. K., Kelenis, D. P., & Goff, S. P. (2022). Two lymphoid cell lines potently silence unintegrated HIV-1 DNAs. Retrovirology, 19(1). https://doi.org/10.1186/s12977-022-00602-7

Benner, S. E., Eby, Y., Zhu, X., Fernandez, R. E., Patel, E. U., Ruff, J. E., Habtehyimer, F., Schmidt, H. A., Kirby, C. S., Hussain, S., Ostrander, D., Desai, N. M., Florman, S., Rana, M. M., Friedman-Moraco, R., Pereira, M. R., Mehta, S., Stock, P., Gilbert, A., … Tobian, A. A. R. (2022). The effect of induction immunosuppression for kidney transplant on the latent HIV reservoir. JCI Insight, 7(21). https://doi.org/10.1172/jci.insight.162968

Parmley, L. E., Harris, T. G., Hakim, A. J., Musuka, G., Chingombe, I., Mugurungi, O., Moyo, B., Mapingure, M., Gozhora, P., Samba, C., & Rogers, J. H. (2022). Recent HIV Infection Among Men Who Have Sex with Men, Transgender Women, and Genderqueer Individuals with Newly Diagnosed HIV Infection in Zimbabwe: Results from a Respondent-Driven Sampling Survey. AIDS Research and Human Retroviruses, 38(11), 834–839. https://doi.org/10.1089/aid.2021.0216

Ebonwu, J., Lassaunière, R., Paximadis, M., Strehlau, R., Gray, G. E., Kuhn, L., & Tiemessen, C. T. (2022). FCGR3A gene duplication, FcγRIIb-232TT and FcγRIIIb-HNA1a associate with an increased risk of vertical acquisition of HIV-1. PLOS ONE, 17(9), e0273933. https://doi.org/10.1371/journal.pone.0273933

Gilbert, P. B., Huang, Y., deCamp, A. C., Karuna, S., Zhang, Y., Magaret, C. A., Giorgi, E. E., Korber, B., Edlefsen, P. T., Rossenkhan, R., Juraska, M., Rudnicki, E., Kochar, N., Huang, Y., Carpp, L. N., Barouch, D. H., Mkhize, N. N., Hermanus, T., Kgagudi, P., … Morris, L. (2022). Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition. Nature Medicine, 28(9), 1924–1932. https://doi.org/10.1038/s41591-022-01953-6

Buckmaster, M. V., & Goff, S. P. (2022). Riplet Binds the Zinc Finger Antiviral Protein (ZAP) and Augments ZAP-Mediated Restriction of HIV-1. Journal of Virology, 96(16). https://doi.org/10.1128/jvi.00526-22

Gaebler, C., Nogueira, L., Stoffel, E., Oliveira, T. Y., Breton, G., Millard, K. G., Turroja, M., Butler, A., Ramos, V., Seaman, M. S., Reeves, J. D., Petroupoulos, C. J., Shimeliovich, I., Gazumyan, A., Jiang, C. S., Jilg, N., Scheid, J. F., Gandhi, R., Walker, B. D., … Nussenzweig, M. C. (2022). Prolonged viral suppression with anti-HIV-1 antibody therapy. Nature, 606(7913), 368–374. https://doi.org/10.1038/s41586-022-04597-1

Delany-Moretlwe, S., Hughes, J. P., Bock, P., Ouma, S. G., Hunidzarira, P., Kalonji, D., Kayange, N., Makhema, J., Mandima, P., Mathew, C., Spooner, E., Mpendo, J., Mukwekwerere, P., Mgodi, N., Ntege, P. N., Nair, G., Nakabiito, C., Nuwagaba-Biribonwoha, H., Panchia, R., … Gaffoor, Z. (2022). Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial. The Lancet, 399(10337), 1779–1789. https://doi.org/10.1016/s0140-6736(22)00538-4

Lulseged, S., Melaku, Z., Habteselassie, A., West, C. A., Gelibo, T., Belete, W., Tefera, F., Farahani, M., Demissie, M., Teferi, W., Abdella, S., Birhanu, S., & Ross, C. E. (2022). Progress towards controlling the HIV epidemic in urban Ethiopia: Findings from the 2017–2018 Ethiopia population-based HIV impact assessment survey. PLOS ONE, 17(2), e0264441. https://doi.org/10.1371/journal.pone.0264441

Geis, F. K., Sabo, Y., Chen, X., Li, Y., Lu, C., & Goff, S. P. (2022). CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection. Proceedings of the National Academy of Sciences, 119(4). https://doi.org/10.1073/pnas.2116735119

Ebonwu, J., Lassaunière, R., Paximadis, M., Goosen, M., Strehlau, R., Gray, G. E., Kuhn, L., & Tiemessen, C. T. (2021). An HIV Vaccine Protective Allele in FCGR2C Associates With Increased Odds of Perinatal HIV Acquisition. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.760571

Nkambule, R., Philip, N. M., Reid, G., Mnisi, Z., Nuwagaba-Biribonwoha, H., Ao, T. T., Ginindza, C., Duong, Y. T., Patel, H., Saito, S., Solmo, C., Brown, K., Moore, C. S., Voetsch, A. C., Bicego, G., Bock, N., Mhlanga, F., Dlamini, T., Mabuza, K., … Justman, J. (2021). HIV incidence, viremia, and the national response in Eswatini: Two sequential population-based surveys. PLOS ONE, 16(12), e0260892. https://doi.org/10.1371/journal.pone.0260892

Siddiqui, M. A., & Yamashita, M. (2021). Toll-Like Receptor (TLR) Signaling Enables Cyclic GMP-AMP Synthase (cGAS) Sensing of HIV-1 Infection in Macrophages. MBio, 12(6). https://doi.org/10.1128/mbio.02817-21