Polytopic fractional delivery of an HIV vaccine alters cellular responses and results in increased epitope breadth in a phase 1 randomized trial

Miner, M. D., deCamp, A., Grunenberg, N., De Rosa, S. C., Fiore-Gartland, A., Bar, K., Spearman, P., Allen, M., Yu, P.-C., Manso, B., Frahm, N., Kalams, S., Baden, L., Keefer, M. C., Scott, H. M., Novak, R., Van Tieu, H., Tomaras, G. D., Kublin, J. G., … Luke-Kilolam, A. (2024). Polytopic fractional delivery of an HIV vaccine alters cellular responses and results in increased epitope breadth in a phase 1 randomized trial. EBioMedicine, 100, 104987. https://doi.org/10.1016/j.ebiom.2024.104987
Authors:
Maurine D. Miner
Allan C. deCamp
Nicole Grunenberg
Stephen C. De Rosa
Andrew Fioré-Gartland
Katharine J. Bar
Paul Spearman
Mary Allen
Pei-Chun Yu
Bryce A. Manso
Nicole Frahm
Spyros A. Kalams
Lindsey R. Baden
Michael T. Yin
Hyman Scott
Richard M. Novak
Hong‐Van Tieu
Georgia D. Tomaras
James G. Kublin
M. Juliana McElrath
Lawrence Corey
Ian Frank
Artur Olhovetchi Kalichman
Paul T. Edlefsen
Mary E. Enama
John Hural
Renée Holt
Debora Dunbar
David T. Crawford
Ian Maki
Jan N. Johannessen
Scharla Estep
Yevgeny Grigoriev
Tamra Madenwald
Marianne Hansen
Drienna Holman
Ramey Fair
Geneviève Meyer
Anya Luke-Kilolam
Affiliated Authors:
Hong‐Van Tieu
Columbia Affiliation:
Subjects:
AIDS Vaccines (MeSH)
HIV Infections (MeSH)
Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (OpenAlex Topic)
Immunobiology of Dendritic Cells (OpenAlex Topic)
Prediction of Peptide-MHC Binding Affinity (OpenAlex Topic)
Author Keywords:
hiv
fractionated delivery
polytopic vaccination
ad5
epitope breadth
elink
Publication Type:
Article
Unique ID:
10.1016/j.ebiom.2024.104987
PMID:
38306894
DOI:
10.1016/j.ebiom.2024.104987
Journal:
EBioMedicine
Publication Date:
Data Source:
OpenAlex
Source Link:
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Record Created: