Alzheimer Disease

Displaying 251 - 300 of 328CSV
Constant, A. B., Basavaraju, R., France, J., Honig, L. S., Marder, K. S., & Provenzano, F. A. (2022). Longitudinal Patterns of Cortical Atrophy on MRI in Patients With Alzheimer Disease With and Without Lewy Body Pathology. Neurology, 99(17). https://doi.org/10.1212/wnl.0000000000200947
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Bhattarai, P., Turgutalp, B., & Kizil, C. (2022). Zebrafish as an Experimental and Preclinical Model for Alzheimer’s Disease. ACS Chemical Neuroscience, 13(20), 2939–2941. https://doi.org/10.1021/acschemneuro.2c00583
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Chapman, S., Weiss, D., Broulíková, H. M., Sunderaraman, P., Barker, M. S., Joyce, J. L., Azar, M., McKeague, I., Kriesl, W. C., & Cosentino, S. (2022). Examining the Role of Aging Perceptions in Subjective Cognitive Decline. Alzheimer Disease & Associated Disorders. https://doi.org/10.1097/wad.0000000000000518
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Casaletto, K. B., Nichols, E., Aslanyan, V., Simone, S. M., Rabin, J. S., La Joie, R., Brickman, A. M., Dams-O’Connor, K., Palta, P., Kumar, R. G., George, K. M., Satizabal, C. L., Schneider, J., & Pa, J. (2022). Sex-specific effects of microglial activation on Alzheimer’s disease proteinopathy in older adults. Brain, 145(10), 3536–3545. https://doi.org/10.1093/brain/awac257
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Calcetas, A. T., Thomas, K. R., Edmonds, E. C., Holmqvist, S. L., Edwards, L., Bordyug, M., Delano-Wood, L., Brickman, A. M., Bondi, M. W., Bangen, K. J., & for the Alzheimer’s Disease Neuroimaging Initiative. (2022). Increased regional white matter hyperintensity volume in objectively-defined subtle cognitive decline and mild cognitive impairment. Neurobiology of Aging, 118, 1–8. https://doi.org/10.1016/j.neurobiolaging.2022.06.002
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Ming, C., Wang, M., Wang, Q., Neff, R., Wang, E., Shen, Q., Reddy, J. S., Wang, X., Allen, M., Ertekin‐Taner, N., De Jager, P. L., Bennett, D. A., Haroutunian, V., Schadt, E., & Zhang, B. (2021). Whole genome sequencing–based copy number variations reveal novel pathways and targets in Alzheimer’s disease. Alzheimer’s & Dementia, 18(10), 1846–1867. Portico. https://doi.org/10.1002/alz.12507
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Silverman, W., Krinsky‐McHale, S. J., Zigman, W. B., & Schupf, N. (2021). Adults with Down syndrome in randomized clinical trials targeting prevention of Alzheimer’s disease. Alzheimer’s & Dementia, 18(10), 1736–1743. Portico. https://doi.org/10.1002/alz.12520
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Iqbal, J., Suarez, M. D., Yadav, P. K., Walsh, M. T., Li, Y., Wu, Y., Huang, Z., James, A. W., Escobar, V., Mokbe, A., Brickman, A. M., Luchsinger, J. A., Dai, K., Moreno, H., & Hussain, M. M. (2022). ATP-binding cassette protein ABCA7 deficiency impairs sphingomyelin synthesis, cognitive discrimination, and synaptic plasticity in the entorhinal cortex. Journal of Biological Chemistry, 298(10), 102411. https://doi.org/10.1016/j.jbc.2022.102411
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Seto, M., Weiner, R. L., Dumitrescu, L., Mahoney, E. R., Hansen, S. L., Janve, V., Khan, O. A., Liu, D., Wang, Y., Menon, V., De Jager, P. L., Schneider, J. A., Bennett, D. A., Gifford, K. A., Jefferson, A. L., & Hohman, T. J. (2022). RNASE6 is a novel modifier of APOE-ε4 effects on cognition. Neurobiology of Aging, 118, 66–76. https://doi.org/10.1016/j.neurobiolaging.2022.06.011
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Buckles, V. D., Xiong, C., Bateman, R. J., Hassenstab, J., Allegri, R., Berman, S. B., Chhatwal, J. P., Danek, A., Fagan, A. M., Ghetti, B., Goate, A., Graff‐Radford, N., Jucker, M., Levin, J., Marcus, D. S., Masters, C. L., McCue, L., McDade, E., … Mori, H. (2021). Different rates of cognitive decline in autosomal dominant and late‐onset Alzheimer disease. Alzheimer’s & Dementia, 18(10), 1754–1764. Portico. https://doi.org/10.1002/alz.12505
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Morris, J. C., Weiner, M., Xiong, C., Beckett, L., Coble, D., Saito, N., Aisen, P. S., Allegri, R., Benzinger, T. L. S., Berman, S. B., Cairns, N. J., Carrillo, M. C., Chui, H. C., Chhatwal, J. P., Cruchaga, C., Fagan, A. M., Farlow, M., Fox, N. C., Ghetti, B., … Buckles, V. D. (2022). Autosomal dominant and sporadic late onset Alzheimer’s disease share a commonin vivopathophysiology. Brain, 145(10), 3594–3607. https://doi.org/10.1093/brain/awac181
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Gao, Y., Felsky, D., Reyes‐Dumeyer, D., Sariya, S., Rentería, M. A., Ma, Y., Klein, H., Cosentino, S., De Jager, P. L., Bennett, D. A., Brickman, A. M., Schellenberg, G. D., Mayeux, R., & Barral, S. (2021). Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance. Alzheimer’s & Dementia, 18(10), 1797–1811. Portico. https://doi.org/10.1002/alz.12524
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Moni, F., Petersen, M. E., Zhang, F., Lao, P. J., Zimmerman, M. E., Gu, Y., Gutierrez, J., Rizvi, B., Laing, K. K., Igwe, K. C., Sathishkumar, M., Keator, D., Andrews, H., Krinsky‐McHale, S., Head, E., Lee, J. H., Lai, F., Yassa, M. A., Rosas, H. D., … Brickman, A. M. (2022). Probing the proteome to explore potential correlates of increased Alzheimer’s‐related cerebrovascular disease in adults with Down syndrome. Alzheimer’s & Dementia, 18(10), 1744–1753. Portico. https://doi.org/10.1002/alz.12627
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Sugden, K., Caspi, A., Elliott, M. L., Bourassa, K. J., Chamarti, K., Corcoran, D. L., Hariri, A. R., Houts, R. M., Kothari, M., Kritchevsky, S., Kuchel, G. A., Mill, J. S., Williams, B. S., Belsky, D. W., & Moffitt, T. E. (2022). Association of Pace of Aging Measured by Blood-Based DNA Methylation With Age-Related Cognitive Impairment and Dementia. Neurology, 99(13). https://doi.org/10.1212/wnl.0000000000200898
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Turgutalp, B., Bhattarai, P., Ercetin, T., Luise, C., Reis, R., Gurdal, E. E., Isaak, A., Biriken, D., Dinter, E., Sipahi, H., Schepmann, D., Junker, A., Wünsch, B., Sippl, W., Gulcan, H. O., Kizil, C., & Yarim, M. (2022). Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease. Journal of Medicinal Chemistry, 65(18), 12292–12318. https://doi.org/10.1021/acs.jmedchem.2c01003
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Mishra, R., Phan, T., Kumar, P., Morrissey, Z., Gupta, M., Hollands, C., Shetti, A., Lopez, K. L., Maienschein-Cline, M., Suh, H., Hen, R., & Lazarov, O. (2022). Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons. Journal of Experimental Medicine, 219(9). https://doi.org/10.1084/jem.20220391
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Lao, P. J., Boehme, A. K., Morales, C., Laing, K. K., Chesebro, A., Igwe, K. C., Gutierrez, J., Gu, Y., Stern, Y., Schupf, N., Manly, J. J., Mayeux, R., & Brickman, A. M. (2022). Amyloid, cerebrovascular disease, and neurodegeneration biomarkers are associated with cognitive trajectories in a racially and ethnically diverse, community-based sample. Neurobiology of Aging, 117, 83–96. https://doi.org/10.1016/j.neurobiolaging.2022.05.004
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Sun, J., Ludvigsson, J. F., Ingre, C., Piehl, F., Wirdefeldt, K., Zagai, U., Ye, W., & Fang, F. (2022). Hospital-treated infections in early- and mid-life and risk of Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis: A nationwide nested case-control study in Sweden. PLOS Medicine, 19(9), e1004092. https://doi.org/10.1371/journal.pmed.1004092
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Tahami Monfared, A. A., Stern, Y., Doogan, S., Irizarry, M., & Zhang, Q. (2022). Stakeholder Insights in Alzheimer’s Disease: Natural Language Processing of Social Media Conversations. Journal of Alzheimer’s Disease, 89(2), 695–708. https://doi.org/10.3233/jad-220422
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Du, F., Yu, Q., Kanaan, N. M., & Yan, S. S. (2022). Mitochondrial oxidative stress contributes to the pathological aggregation and accumulation of tau oligomers in Alzheimer’s disease. Human Molecular Genetics, 31(15), 2498–2507. https://doi.org/10.1093/hmg/ddab363
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Janelidze, S., Christian, B. T., Price, J., Laymon, C., Schupf, N., Klunk, W. E., Lott, I., Silverman, W., Rosas, H. D., Zaman, S., Mapstone, M., Lai, F., Ances, B. M., Handen, B. L., & Hansson, O. (2022). Detection of Brain Tau Pathology in Down Syndrome Using Plasma Biomarkers. JAMA Neurology, 79(8), 797. https://doi.org/10.1001/jamaneurol.2022.1740
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Rabin, J. S., Nichols, E., La Joie, R., Casaletto, K. B., Palta, P., Dams-O’Connor, K., Kumar, R. G., George, K. M., Satizabal, C. L., Schneider, J. A., Pa, J., & Brickman, A. M. (2022). Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline. Brain, 145(8), 2823–2833. https://doi.org/10.1093/brain/awac178
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Kamath, V., Senjem, M. L., Spychalla, A. J., Chen, H., Palta, P., Mosley, T. H., Windham, B. G., Griswold, M., Knopman, D. S., Gottesman, R. F., Jack, C. R., Sharrett, A. R., & Schneider, A. L. C. (2022). The Neuroanatomic Correlates of Olfactory Identification Impairment in Healthy Older Adults and in Persons with Mild Cognitive Impairment. Journal of Alzheimer’s Disease, 89(1), 233–245. https://doi.org/10.3233/jad-220228
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Rajabli, F., Beecham, G. W., Hendrie, H. C., Baiyewu, O., Ogunniyi, A., Gao, S., Kushch, N. A., Lipkin-Vasquez, M., Hamilton-Nelson, K. L., Young, J. I., Dykxhoorn, D. M., Nuytemans, K., Kunkle, B. W., Wang, L., Jin, F., Liu, X., Feliciano-Astacio, B. E., Schellenberg, G. D., … Vance, J. M. (2022). A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer’s Disease in African Ancestry. PLOS Genetics, 18(7), e1009977. https://doi.org/10.1371/journal.pgen.1009977
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Peris, L., Parato, J., Qu, X., Soleilhac, J. M., Lanté, F., Kumar, A., Pero, M. E., Martínez-Hernández, J., Corrao, C., Falivelli, G., Payet, F., Gory-Fauré, S., Bosc, C., Blanca Ramirez, M., Sproul, A., Brocard, J., Di Cara, B., Delagrange, P., Buisson, A., … Andrieux, A. (2022). Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer’s disease. Brain, 145(7), 2486–2506. https://doi.org/10.1093/brain/awab436
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Lee, A. J., Raghavan, N. S., Bhattarai, P., Siddiqui, T., Sariya, S., Reyes-Dumeyer, D., Flowers, X. E., Cardoso, S. A. L., De Jager, P. L., Bennett, D. A., Schneider, J. A., Menon, V., Wang, Y., Lantigua, R. A., Medrano, M., Rivera, D., Jiménez-Velázquez, I. Z., Kukull, W. A., Brickman, A. M., … Mayeux, R. (2022). FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease. Acta Neuropathologica, 144(1), 59–79. https://doi.org/10.1007/s00401-022-02431-6
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Eissman, J. M., Dumitrescu, L., Mahoney, E. R., Smith, A. N., Mukherjee, S., Lee, M. L., Scollard, P., Choi, S. E., Bush, W. S., Engelman, C. D., Lu, Q., Fardo, D. W., Trittschuh, E. H., Mez, J., Kaczorowski, C. C., Hernandez Saucedo, H., Widaman, K. F., Buckley, R. F., Properzi, M. J., … Hohman, T. J. (2022). Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease. Brain, 145(7), 2541–2554. https://doi.org/10.1093/brain/awac177
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Cosacak, M. I., Bhattarai, P., De Jager, P. L., Menon, V., Tosto, G., & Kizil, C. (2022). Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer’s Disease. Cells, 11(11), 1807. https://doi.org/10.3390/cells11111807
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Kumar, J. S. D., Molotkov, A., Kim, J., Carberry, P., Idumonyi, S., Castrillon, J., Duff, K., Shneider, N. A., & Mintz, A. (2022). Preclinical evaluation of a microtubule PET ligand [11C]MPC-6827 in tau and amyotrophic lateral sclerosis animal models. Pharmacological Reports, 74(3), 539–544. https://doi.org/10.1007/s43440-022-00359-y
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Kizil, C., Sariya, S., Kim, Y. A., Rajabli, F., Martin, E., Reyes-Dumeyer, D., Vardarajan, B., Maldonado, A., Haines, J. L., Mayeux, R., Jiménez-Velázquez, I. Z., Santa-Maria, I., & Tosto, G. (2022). Admixture Mapping of Alzheimer’s disease in Caribbean Hispanics identifies a new locus on 22q13.1. Molecular Psychiatry, 27(6), 2813–2820. https://doi.org/10.1038/s41380-022-01526-6
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Gu, Y., Kociolek, A., Fernandez, K. K., Cosentino, S. A., Zhu, C. W., Jin, Z., Leverenz, J. B., & Stern, Y. B. (2022). Clinical Trajectories at the End of Life in Autopsy-Confirmed Dementia Patients With Alzheimer Disease and Lewy Bodies Pathologies. Neurology, 98(21). https://doi.org/10.1212/wnl.0000000000200259
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Tsiakiri, A., Koutzmpi, V., Megagianni, S., Toumaian, M., Geronikola, N., Despoti, A., Kanellopoulou, S., Arampatzi, X., Margioti, E., Davila, A., Zoi, P., Kalligerou, F., Liozidou, A., Tsapanou, A., & Sakka, P. (2022). Remote neuropsychological evaluation of older adults. Applied Neuropsychology: Adult, 31(5), 796–803. https://doi.org/10.1080/23279095.2022.2074850
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Kim, H., Levine, A., Cohen, D., Gehrman, P., Zhu, X., Devanand, D. P., Lee, S., & Goldberg, T. E. (2022). The Role of Amyloid, Tau, and APOE Genotype on the Relationship Between Informant-Reported Sleep Disturbance and Alzheimer’s Disease Risks. Journal of Alzheimer’s Disease, 87(4), 1567–1580. https://doi.org/10.3233/jad-215417
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Reiken, S., Sittenfeld, L., Dridi, H., Liu, Y., Liu, X., & Marks, A. R. (2022). Alzheimer’s‐like signaling in brains of COVID‐19 patients. Alzheimer’s & Dementia, 18(5), 955–965. Portico. https://doi.org/10.1002/alz.12558
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Chen, S., Acosta, D., Li, L., Liang, J., Chang, Y., Wang, C., Fitzgerald, J., Morrison, C., Goulbourne, C. N., Nakano, Y., Villegas, N. C. H., Venkataraman, L., Brown, C., Serrano, G. E., Bell, E., Wemlinger, T., Wu, M., Kokiko-Cochran, O. N., Popovich, P., … Fu, H. (2022). Wolframin is a novel regulator of tau pathology and neurodegeneration. Acta Neuropathologica, 143(5), 547–569. https://doi.org/10.1007/s00401-022-02417-4
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Brickman, A. M., Manly, J. J., Honig, L. S., Sanchez, D., Reyes‐Dumeyer, D., Lantigua, R. A., Vonsattel, J. P., Teich, A. F., Kang, M. S., Dage, J. L., & Mayeux, R. (2022). Correlation of plasma and neuroimaging biomarkers in Alzheimer’s disease. Annals of Clinical and Translational Neurology, 9(5), 756–761. Portico. https://doi.org/10.1002/acn3.51529
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Younan, D., Wang, X., Gruenewald, T., Gatz, M., Serre, M. L., Vizuete, W., Braskie, M. N., Woods, N. F., Kahe, K., Garcia, L., Lurmann, F., Manson, J. E., Chui, H. C., Wallace, R. B., Espeland, M. A., & Chen, J.-C. (2021). Racial/Ethnic Disparities in Alzheimer’s Disease Risk: Role of Exposure to Ambient Fine Particles. The Journals of Gerontology: Series A, 77(5), 977–985. https://doi.org/10.1093/gerona/glab231
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Guisle, I., Canet, G., Pétry, S., Fereydouni-Forouzandeh, P., Morin, F., Kérauden, R., Whittington, R. A., Calon, F., Hébert, S. S., & Planel, E. (2022). Sauna-like conditions or menthol treatment reduce tau phosphorylation through mild hyperthermia. Neurobiology of Aging, 113, 118–130. https://doi.org/10.1016/j.neurobiolaging.2022.02.011
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Rippon, B., Palta, P., Tahmi, M., Sherwood, G., Soto, L., Cespedes, S., Mesen, Y., He, H., Laing, K., Moreno, H., Teresi, J., Razlighi, Q., Brickman, A. M., Zetterberg, H., & Luchsinger, J. A. (2022). Plasma Amyloid and in vivo Brain Amyloid in Late Middle-Aged Hispanics. Journal of Alzheimer’s Disease, 87(3), 1229–1238. https://doi.org/10.3233/jad-210391
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Libon, D. J., Swenson, R., Lamar, M., Price, C. C., Baliga, G., Pascual-Leone, A., Au, R., Cosentino, S., & Andersen, S. L. (2022). The Boston Process Approach and Digital Neuropsychological Assessment: Past Research and Future Directions. Journal of Alzheimer’s Disease, 87(4), 1419–1432. https://doi.org/10.3233/jad-220096
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Ma, Y., Yu, L., Olah, M., Smith, R., Oatman, S. R., Allen, M., Pishva, E., Zhang, B., Menon, V., Ertekin‐Taner, N., Lunnon, K., Bennett, D. A., Klein, H., & De Jager, P. L. (2021). Epigenomic features related to microglia are associated with attenuated effect ofAPOEε4 on Alzheimer’s disease risk in humans. Alzheimer’s & Dementia, 18(4), 688–699. Portico. https://doi.org/10.1002/alz.12425
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Barker, M. S., Gottesman, R. T., Manoochehri, M., Chapman, S., Appleby, B. S., Brushaber, D., Devick, K. L., Dickerson, B. C., Domoto-Reilly, K., Fields, J. A., Forsberg, L. K., Galasko, D. R., Ghoshal, N., Goldman, J., Graff-Radford, N. R., Grossman, M., Heuer, H. W., Hsiung, G.-Y., Knopman, D. S., … Weintraub, S. (2022). Proposed research criteria for prodromal behavioural variant frontotemporal dementia. Brain, 145(3), 1079–1097. https://doi.org/10.1093/brain/awab365
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Neuner, S. M., Telpoukhovskaia, M., Menon, V., O’Connell, K. M. S., Hohman, T. J., & Kaczorowski, C. C. (2022). Translational approaches to understanding resilience to Alzheimer’s disease. Trends in Neurosciences, 45(5), 369–383. https://doi.org/10.1016/j.tins.2022.02.005
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