Alzheimer Disease

Displaying 101 - 150 of 294CSV
Hojjati, S. H., Chiang, G. C., Butler, T. A., de Leon, M., Gupta, A., Li, Y., Sabuncu, M. R., Feiz, F., Nayak, S., Shteingart, J., Ozoria, S., Gholipour Picha, S., Stern, Y., Luchsinger, J. A., Devanand, D. P., & Razlighi, Q. R. (2024). Remote Associations Between Tau and Cortical Amyloid-β Are Stage-Dependent. Journal of Alzheimer’s Disease, 98(4), 1467–1482. https://doi.org/10.3233/jad-231362
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Goldberg, T. E., Lee, S., Devanand, D. P., & Schneider, L. S. (2023). Comparison of relative change with effect size metrics in Alzheimer’s disease clinical trials. Journal of Neurology, Neurosurgery & Psychiatry, 95(1), 2–7. https://doi.org/10.1136/jnnp-2023-331941
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Acquarone, E., Argyrousi, E. K., Arancio, O., Watterson, D. M., & Roy, S. M. (2024). The 5HT2b Receptor in Alzheimer’s Disease: Increased Levels in Patient Brains and Antagonist Attenuation of Amyloid and Tau Induced Dysfunction. Journal of Alzheimer’s Disease, 98(4), 1349–1360. https://doi.org/10.3233/jad-240063
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Kim, Y. A., Mellen, M., Kizil, C., & Santa‐Maria, I. (2023). Mechanisms linking cerebrovascular dysfunction and tauopathy: Adding a layer of epiregulatory complexity. British Journal of Pharmacology, 181(6), 879–895. Portico. https://doi.org/10.1111/bph.16280
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Cross, D. A., Bucy, T. I., Rahman, M., & McHugh, J. P. (2023). Access to preferred skilled nursing facilities: Transitional care pathways for patients with Alzheimer’s disease and related dementias. Health Services Research, 59(2). Portico. https://doi.org/10.1111/1475-6773.14263
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Haut, F., Argyrousi, E. K., & Arancio, O. (2023). Re-Arranging the Puzzle between the Amyloid-Beta and Tau Pathology: An APP-Centric Approach. International Journal of Molecular Sciences, 25(1), 259. https://doi.org/10.3390/ijms25010259
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Li, C., Stebbins, R. C., Noppert, G. A., Carney, C. X., Liu, C., Sapp, A. R. M., Watson, E. J., & Aiello, A. E. (2023). Peripheral immune function and Alzheimer’s disease: a living systematic review and critical appraisal. Molecular Psychiatry, 29(6), 1895–1905. https://doi.org/10.1038/s41380-023-02355-x
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Wang, Q., Tao, S., Xing, L., Liu, J., Xu, C., Xu, X., Ding, H., Shen, Q., Yu, X., & Zheng, Y. (2023). SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease. European Journal of Medical Research, 28(1). https://doi.org/10.1186/s40001-023-01360-8
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Sarnowski, C., Huan, T., Ma, Y., Joehanes, R., Beiser, A., DeCarli, C. S., Heard-Costa, N. L., Levy, D., Lin, H., Liu, C.-T., Liu, C., Meigs, J. B., Satizabal, C. L., Florez, J. C., Hivert, M.-F., Dupuis, J., De Jager, P. L., Bennett, D. A., Seshadri, S., & Morrison, A. C. (2023). Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer’s disease at CPT1A locus. Clinical Epigenetics, 15(1). https://doi.org/10.1186/s13148-023-01589-4
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Mehta, N. H., Zhou, L., Li, Y., McIntire, L. B., Nordvig, A., Butler, T., de Leon, M., & Chiang, G. C. (2023). Peripheral immune cell imbalance is associated with cortical beta-amyloid deposition and longitudinal cognitive decline. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-34012-2
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Javitt, D. C., Martinez, A., Sehatpour, P., Beloborodova, A., Habeck, C., Gazes, Y., Bermudez, D., Razlighi, Q. R., Devanand, D. P., & Stern, Y. (2023). Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment. Alzheimer’s Research & Therapy, 15(1). https://doi.org/10.1186/s13195-023-01189-7
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Yang, H.-S., Teng, L., Kang, D., Menon, V., Ge, T., Finucane, H. K., Schultz, A. P., Properzi, M., Klein, H.-U., Chibnik, L. B., Schneider, J. A., Bennett, D. A., Hohman, T. J., Mayeux, R. P., Johnson, K. A., De Jager, P. L., & Sperling, R. A. (2023). Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-43132-2
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Lynch, M. T., Taub, M. A., Farfel, J. M., Yang, J., Abadir, P., De Jager, P. L., Grodstein, F., Bennett, D. A., & Mathias, R. A. (2023). Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer’s disease. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-41400-1
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Scalco, R., Saito, N., Beckett, L., Nguyen, M.-L., Huie, E., Wang, H.-P., Flaherty, D. A., Honig, L. S., DeCarli, C., Rissman, R. A., Teich, A. F., Jin, L.-W., & Dugger, B. N. (2023). The neuropathological landscape of Hispanic and non-Hispanic White decedents with Alzheimer disease. Acta Neuropathologica Communications, 11(1). https://doi.org/10.1186/s40478-023-01574-1
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Gomes, P. A., Bodo, C., Nogueras-Ortiz, C., Samiotaki, M., Chen, M., Soares-Cunha, C., Silva, J. M., Coimbra, B., Stamatakis, G., Santos, L., Panayotou, G., Tzouanou, F., Waites, C. L., Gatsogiannis, C., Sousa, N., Kapogiannis, D., Costa-Silva, B., & Sotiropoulos, I. (2023). A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology. Cell Communication and Signaling, 21(1). https://doi.org/10.1186/s12964-023-01045-z
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Chou, V., Pearse, R. V., Aylward, A. J., Ashour, N., Taga, M., Terzioglu, G., Fujita, M., Fancher, S. B., Sigalov, A., Benoit, C. R., Lee, H., Lam, M., Seyfried, N. T., Bennett, D. A., De Jager, P. L., Menon, V., & Young-Pearse, T. L. (2023). INPP5D regulates inflammasome activation in human microglia. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-42819-w
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Park, D. K., Chen, M., Kim, S., Joo, Y. Y., Loving, R. K., Kim, H. S., Cha, J., Yoo, S., & Kim, J. H. (2023). Overestimated prediction using polygenic prediction derived from summary statistics. BMC Genomic Data, 24(1). https://doi.org/10.1186/s12863-023-01151-4
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Kang, M., Ang, T. F. A., Devine, S. A., Sherva, R., Mukherjee, S., Trittschuh, E. H., Gibbons, L. E., Scollard, P., Lee, M., Choi, S.-E., Klinedinst, B., Nakano, C., Dumitrescu, L. C., Durant, A., Hohman, T. J., Cuccaro, M. L., Saykin, A. J., Kukull, W. A., Bennett, D. A., … Farrer, L. A. (2023). A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores. Molecular Neurodegeneration, 18(1). https://doi.org/10.1186/s13024-023-00633-4
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Membreno, R., Thomas, K. R., Calcetas, A. T., Edwards, L., Bordyug, M., Showell, M., Stanfill, M., Brenner, E. K., Walker, K. S., Rotblatt, L. J., Brickman, A. M., Edmonds, E. C., & Bangen, K. J. (2023). Regional White Matter Hyperintensities Relate to Specific Cognitive Abilities in Older Adults Without Dementia. Alzheimer Disease & Associated Disorders, 37(4), 303–309. https://doi.org/10.1097/wad.0000000000000585
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Kociolek, A. J., Fernandez, K. K., Hernandez, M., Jin, Z., Cosentino, S., Zhu, C. W., Gu, Y., Devanand, D. P., & Stern, Y. (2023). Neuropsychiatric Symptoms and Trajectories of Dependence and Cognition in a Sample of Community-dwelling Older Adults with Dementia. Current Alzheimer Research, 20(6), 409–419. https://doi.org/10.2174/1567205020666230908163414
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Eissman, J. M., Archer, D. B., Mukherjee, S., Lee, M. L., Choi, S., Scollard, P., Trittschuh, E. H., Mez, J. B., Bush, W. S., Kunkle, B. W., Naj, A. C., Gifford, K. A., Cuccaro, M. L., Cruchaga, C., Pericak‐Vance, M. A., Farrer, L. A., Wang, L., Schellenberg, G. D., … Mayeux, R. P. (2023). Sex‐specific genetic architecture of late‐life memory performance. Alzheimer’s & Dementia, 20(2), 1250–1267. Portico. https://doi.org/10.1002/alz.13507
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Archer, D. B., Eissman, J. M., Mukherjee, S., Lee, M. L., Choi, S., Scollard, P., Trittschuh, E. H., Mez, J. B., Bush, W. S., Kunkle, B. W., Naj, A. C., Gifford, K. A., Cuccaro, M. L., Pericak‐Vance, M. A., Farrer, L. A., Wang, L., Schellenberg, G. D., Mayeux, R. P., … Haines, J. L. (2023). Longitudinal change in memory performance as a strong endophenotype for Alzheimer’s disease. Alzheimer’s & Dementia, 20(2), 1268–1283. Portico. https://doi.org/10.1002/alz.13508
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Azar, M., Chapman, S., Joyce, J., Schultheis, M., Zhang, Z., Waltrip, L., Shagalow, S., Zeiger, P., Sunderaraman, P., & Cosentino, S. (2023). Education as a Moderator of Help Seeking Behavior in Subjective Cognitive Decline. Alzheimer Disease & Associated Disorders, 37(3), 184–188. https://doi.org/10.1097/wad.0000000000000571
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Dark, H. E., Paterson, C., Daya, G. N., Peng, Z., Duggan, M. R., Bilgel, M., An, Y., Moghekar, A., Davatzikos, C., Resnick, S. M., Loupy, K., Simpson, M., Candia, J., Mosley, T., Coresh, J., Palta, P., Ferrucci, L., Shapiro, A., Williams, S. A., & Walker, K. A. (2023). Proteomic Indicators of Health Predict Alzheimer’s Disease Biomarker Levels and Dementia Risk. Annals of Neurology, 95(2), 260–273. Portico. https://doi.org/10.1002/ana.26817
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Fulop, T., Ramassamy, C., Lévesque, S., Frost, E. H., Laurent, B., Lacombe, G., Khalil, A., Larbi, A., Hirokawa, K., Desroches, M., Rodrigues, S., Bourgade, K., Cohen, A. A., & Witkowski, J. M. (2023). Viruses - a major cause of amyloid deposition in the brain. Expert Review of Neurotherapeutics, 23(9), 775–790. https://doi.org/10.1080/14737175.2023.2244162
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Dage, J. L., Eloyan, A., Thangarajah, M., Hammers, D. B., Fagan, A. M., Gray, J. D., Schindler, S. E., Snoddy, C., Nudelman, K. N. H., Faber, K. M., Foroud, T., Aisen, P., Griffin, P., Grinberg, L. T., Iaccarino, L., Kirby, K., Kramer, J., Koeppe, R., … Kukull, W. A. (2023). Cerebrospinal fluid biomarkers in the Longitudinal Early‐onset Alzheimer’s Disease Study. Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13399
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Hammers, D. B., Eloyan, A., Taurone, A., Thangarajah, M., Beckett, L., Gao, S., Kirby, K., Aisen, P., Dage, J. L., Foroud, T., Griffin, P., Grinberg, L. T., Jack, C. R., Kramer, J., Koeppe, R., Kukull, W. A., Mundada, N. S., La Joie, R., … Soleimani‐Meigooni, D. N. (2023). Profiling baseline performance on the Longitudinal Early‐Onset Alzheimer’s Disease Study (LEADS) cohort near the midpoint of data collection. Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13160
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Bushnell, J., Hammers, D. B., Aisen, P., Dage, J. L., Eloyan, A., Foroud, T., Grinberg, L. T., Iaccarino, L., Jack, C. R., Kirby, K., Kramer, J., Koeppe, R., Kukull, W. A., La Joie, R., Mundada, N. S., Murray, M. E., Nudelman, K., Rumbaugh, M., … Soleimani‐Meigooni, D. N. (2023). Influence of amyloid and diagnostic syndrome on non‐traditional memory scores in early‐onset Alzheimer’s disease. Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13434
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Eloyan, A., Thangarajah, M., An, N., Borowski, B. J., Reddy, A. L., Aisen, P., Dage, J. L., Foroud, T., Ghetti, B., Griffin, P., Hammers, D., Iaccarino, L., Jack, C. R., Kirby, K., Kramer, J., Koeppe, R., Kukull, W. A., La Joie, R., … Mundada, N. S. (2023). White matter hyperintensities are higher among early‐onset Alzheimer’s disease participants than their cognitively normal and early‐onset nonAD peers: Longitudinal Early‐onset Alzheimer’s Disease Study (LEADS). Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13402
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Hammers, D. B., Nemes, S., Diedrich, T., Eloyan, A., Kirby, K., Aisen, P., Kramer, J., Nudelman, K., Foroud, T., Rumbaugh, M., Atri, A., Day, G. S., Duara, R., Graff‐Radford, N. R., Honig, L. S., Jones, D. T., Masdeu, J. C., Mendez, M. F., … Musiek, E. (2023). Learning slopes in early‐onset Alzheimer’s disease. Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13159
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Qian, H., Khadka, A., Martinez, S. M., Singh, S., Brenowitz, W. D., Zeki Al Hazzouri, A., Hill-Jarrett, T. G., Glymour, M. M., & Vable, A. M. (2023). Food Insecurity, Memory, and Dementia Among US Adults Aged 50 Years and Older. JAMA Network Open, 6(11), e2344186. https://doi.org/10.1001/jamanetworkopen.2023.44186
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Nemes, S., Logan, P. E., Manchella, M. K., Mundada, N. S., La Joie, R., Polsinelli, A. J., Hammers, D. B., Koeppe, R. A., Foroud, T. M., Nudelman, K. N., Eloyan, A., Iaccarino, L., Dorsant‐Ardón, V., Taurone, A., Thangarajah, M., Dage, J. L., Aisen, P., Grinberg, L. T., … Jack, C. R. (2023). Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early‐onset Alzheimer’s disease. Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13403
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Polsinelli, A. J., Wonderlin, R. J., Hammers, D. B., Garcia, A. P., Eloyan, A., Taurone, A., Thangarajah, M., Beckett, L., Gao, S., Wang, S., Kirby, K., Logan, P. E., Aisen, P., Dage, J. L., Foroud, T., Griffin, P., Iaccarino, L., Kramer, J. H., … Koeppe, R. (2023). Baseline neuropsychiatric symptoms and psychotropic medication use midway through data collection of the Longitudinal Early‐Onset Alzheimer’s Disease Study (LEADS) cohort. Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13344
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Sun, J., Ludvigsson, J. F., Roelstraete, B., Pedersen, N. L., Pawitan, Y., Wirdefeldt, K., & Fang, F. (2022). Gastrointestinal biopsy of normal mucosa or nonspecific inflammation and risk of neurodegenerative disease: Nationwide matched cohort study. European Journal of Neurology, 30(11), 3430–3439. Portico. https://doi.org/10.1111/ene.15654
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Nuytemans, K., Rajabli, F., Jean-Francois, M., Kurup, J. T., Adams, L. D., Starks, T. D., Whitehead, P. L., Kunkle, B. W., Caban-Holt, A., Haines, J. L., Cuccaro, M. L., Vance, J. M., Byrd, G. S., Beecham, G. W., Reitz, C., & Pericak-Vance, M. A. (2024). Genetic analyses in multiplex families confirms chromosome 5q35 as a risk locus for Alzheimer’s Disease in individuals of African Ancestry. Neurobiology of Aging, 133, 125–133. https://doi.org/10.1016/j.neurobiolaging.2023.10.010
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Roberts, J. A., Elkind, M. S. V., Liu, M., Wright, C. B., Rundek, T., & Gutierrez, J. (2023). Herpes simplex virus 2 serology is associated with thinner whole-brain cortex in community-dwelling older adults. Journal of the Neurological Sciences, 454, 120856. https://doi.org/10.1016/j.jns.2023.120856
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Sun, Y., Moghekar, A., Soldan, A., Pettigrew, C., Greenberg, B., Albert, M., & Wang, M.-C. (2023). Cerebrospinal Fluid Alzheimer’s Disease Biomarker Patterns of Change Prior to the Onset of Mild Cognitive Impairment. Journal of Alzheimer’s Disease, 96(1), 287–300. https://doi.org/10.3233/jad-230807
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Rahmani, F., Brier, M. R., Gordon, B. A., McKay, N., Flores, S., Keefe, S., Hornbeck, R., Ances, B., Joseph‐Mathurin, N., Xiong, C., Wang, G., Raji, C. A., Libre‐Guerra, J. J., Perrin, R. J., McDade, E., Daniels, A., Karch, C., Day, G. S., … Brickman, A. M. (2023). T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease. Human Brain Mapping, 44(18), 6375–6387. Portico. https://doi.org/10.1002/hbm.26514
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Gorijala, P., Aslam, M. M., Dang, L. T., Xicota, L., Fernandez, M. V., Sung, Y. J., Fan, K., Feingold, E., Surace, E. I., Chhatwal, J. P., Hom, C. L., Hartley, S. L., Hassenstab, J., Perrin, R. J., Mapstone, M., Zaman, S. H., Ances, B. M., Kamboh, M. I., … Lee, J. H. (2023). Alzheimer’s polygenic risk scores are associated with cognitive phenotypes in Down syndrome. Alzheimer’s & Dementia, 20(2), 1038–1049. Portico. https://doi.org/10.1002/alz.13506
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Touroutoglou, A., Katsumi, Y., Brickhouse, M., Zaitsev, A., Eckbo, R., Aisen, P., Beckett, L., Dage, J. L., Eloyan, A., Foroud, T., Ghetti, B., Griffin, P., Hammers, D., Jack, C. R., Kramer, J. H., Iaccarino, L., Joie, R. L., Mundada, N. S., … Koeppe, R. (2023). The Sporadic Early‐onset Alzheimer’s Disease Signature Of Atrophy: Preliminary Findings From The Longitudinal Early‐onset Alzheimer’s Disease Study (LEADS) Cohort. Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13466
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Simon, S. S., Varangis, E., Lee, S., Gu, Y., Gazes, Y., Razlighi, Q. R., Habeck, C., & Stern, Y. (2024). In vivo tau is associated with change in memory and processing speed, but not reasoning, in cognitively unimpaired older adults. Neurobiology of Aging, 133, 28–38. https://doi.org/10.1016/j.neurobiolaging.2023.10.001
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Nudelman, K. N. H., Jackson, T., Rumbaugh, M., Eloyan, A., Abreu, M., Dage, J. L., Snoddy, C., Faber, K. M., Foroud, T., Hammers, D. B., Taurone, A., Thangarajah, M., Aisen, P., Beckett, L., Kramer, J., Koeppe, R., Kukull, W. A., Murray, M. E., … Toga, A. W. (2023). Pathogenic variants in the Longitudinal Early‐onset Alzheimer’s Disease Study cohort. Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13482
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Kim, H., Zhu, X., Zhao, Y., Bell, S. A., Gehrman, P. R., Cohen, D., Devanand, D. P., Goldberg, T. E., & Lee, S. (2023). Resting-state functional connectivity changes in older adults with sleep disturbance and the role of amyloid burden. Molecular Psychiatry, 28(10), 4399–4406. https://doi.org/10.1038/s41380-023-02214-9
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Gicas, K. M., Honer, W. G., Petyuk, V. A., Wilson, R. S., Boyle, P. A., Leurgans, S. E., Schneider, J. A., De Jager, P. L., & Bennett, D. A. (2023). Primacy and recency effects in verbal memory are differentially associated with post-mortem frontal cortex p-tau 217 and 202 levels in a mixed sample of community-dwelling older adults. Journal of Clinical and Experimental Neuropsychology, 45(8), 770–785. https://doi.org/10.1080/13803395.2023.2232583
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Fernández, K. K., Kociolek, A. J., Lao, P. J., Stern, Y., Manly, J. J., & Vonk, J. M. J. (2023). Longitudinal decline in semantic versus letter fluency, but not their ratio, marks incident Alzheimer’s disease in Latinx Spanish-speaking older individuals. Journal of the International Neuropsychological Society, 29(8), 775–782. https://doi.org/10.1017/s1355617722000856
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Zhang, Y., Shen, Y., Liufu, N., Liu, L., Li, W., Shi, Z., Zheng, H., Mei, X., Chen, C.-Y., Jiang, Z., Abtahi, S., Dong, Y., Liang, F., Shi, Y., Cheng, L. L., Yang, G., Kang, J. X., Wilkinson, J. E., & Xie, Z. (2023). Transmission of Alzheimer’s disease-associated microbiota dysbiosis and its impact on cognitive function: evidence from mice and patients. Molecular Psychiatry, 28(10), 4421–4437. https://doi.org/10.1038/s41380-023-02216-7
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Adkins‐Jackson, P. B., Kraal, A. Z., Hill‐Jarrett, T. G., George, K. M., Deters, K. D., Besser, L. M., Avila‐Rieger, J. F., Turney, I., & Manly, J. J. (2023). Riding the merry‐go‐round of racial disparities in ADRD research. Alzheimer’s & Dementia, 19(10), 4735–4742. Portico. https://doi.org/10.1002/alz.13359
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