Alzheimer Disease

Displaying 201 - 250 of 328CSV
Winfree, R. L., Seto, M., Dumitrescu, L., Menon, V., De Jager, P., Wang, Y., Schneider, J., Bennett, D. A., Jefferson, A. L., & Hohman, T. J. (2023). TREM2 gene expression associations with Alzheimer’s disease neuropathology are region-specific: implications for cortical versus subcortical microglia. Acta Neuropathologica, 145(6), 733–747. https://doi.org/10.1007/s00401-023-02564-2
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Nichols, E., Brickman, A. M., Casaletto, K. B., Dams‐O’Connor, K., George, K. M., Kumar, R. G., Palta, P., Rabin, J. S., Satizabal, C. L., Schneider, J., Pa, J., & La Joie, R. (2022). AD and non‐AD mediators of the pathway between the APOE genotype and cognition. Alzheimer’s & Dementia, 19(6), 2508–2519. Portico. https://doi.org/10.1002/alz.12885
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Habes, M., Jacobson, A. M., Braffett, B. H., Rashid, T., Ryan, C. M., Shou, H., Cui, Y., Davatzikos, C., Luchsinger, J. A., Biessels, G. J., Bebu, I., Gubitosi-Klug, R. A., Bryan, R. N., & Nasrallah, I. M. (2023). Patterns of Regional Brain Atrophy and Brain Aging in Middle- and Older-Aged Adults With Type 1 Diabetes. JAMA Network Open, 6(6), e2316182. https://doi.org/10.1001/jamanetworkopen.2023.16182
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Horie, K., Li, Y., Barthélemy, N. R., Gordon, B., Hassenstab, J., Benzinger, T. L. S., Fagan, A. M., Morris, J. C., Karch, C. M., Xiong, C., Allegri, R., Mendez, P. C., Ikeuchi, T., Kasuga, K., Noble, J., Farlow, M., Chhatwal, J., Day, G., … Schofield, P. R. (2023). Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer’s Disease. Annals of Neurology, 93(6), 1158–1172. Portico. https://doi.org/10.1002/ana.26620
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Kloske, C. M., Barnum, C. J., Batista, A. F., Bradshaw, E. M., Brickman, A. M., Bu, G., Dennison, J., Gearon, M. D., Goate, A. M., Haass, C., Heneka, M. T., Hu, W. T., Huggins, L. K. L., Jones, N. S., Koldamova, R., Lemere, C. A., Liddelow, S. A., Marcora, E., Marsh, S. E., … Carrillo, M. C. (2023). APOE and immunity: Research highlights. Alzheimer’s & Dementia, 19(6), 2677–2696. Portico. https://doi.org/10.1002/alz.13020
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Rajabli, F., Tosto, G., Hamilton‐Nelson, K. L., Kunkle, B. W., Vardarajan, B. N., Naj, A., Whitehead, P. G., Gardner, O. K., Bush, W. S., Sariya, S., Mayeux, R. P., Farrer, L. A., Cuccaro, M. L., Vance, J. M., Griswold, A. J., Schellenberg, G. D., Haines, J. L., Byrd, G. S., … Reitz, C. (2022). Admixture mapping identifies novel Alzheimer’s disease risk regions in African Americans. Alzheimer’s & Dementia, 19(6), 2538–2548. Portico. https://doi.org/10.1002/alz.12865
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Paschalidis, M., Konstantyner, T. C. R. de O., Simon, S. S., & Martins, C. B. (2023). Trends in mortality from Alzheimer’s disease in Brazil, 2000-2019. Epidemiologia e Serviços de Saúde, 32(2). https://doi.org/10.1590/s2237-96222023000200002
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Luo, J., Thomassen, J. Q., Bellenguez, C., Grenier-Boley, B., de Rojas, I., Castillo, A., Parveen, K., Küçükali, F., Nicolas, A., Peters, O., Schneider, A., Dichgans, M., Rujescu, D., Scherbaum, N., Jürgen, D., Riedel-Heller, S., Hausner, L., Porcel, L. M., … Frikke-Schmidt, R. (2023). Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease. JAMA Network Open, 6(5), e2313734. https://doi.org/10.1001/jamanetworkopen.2023.13734
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Qiao, M., Lee, A. J., Reyes‐Dumeyer, D., Tosto, G., Faber, K., Goate, A., Renton, A., Chao, M., Boeve, B., Cruchaga, C., Pericak‐Vance, M., Haines, J. L., Rosenberg, R., Tsuang, D., Sweet, R. A., Bennett, D. A., Wilson, R. S., Foroud, T., Mayeux, R., & Vardarajan, B. N. (2023). Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease. Annals of Clinical and Translational Neurology, 10(5), 744–756. Portico. https://doi.org/10.1002/acn3.51757
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Wu, R., Tripathy, S., Menon, V., Yu, L., Buchman, A. S., Bennett, D. A., De Jager, P. L., & Lim, A. S. P. (2022). Fragmentation of rest periods, astrocyte activation, and cognitive decline in older adults with and without Alzheimer’s disease. Alzheimer’s & Dementia, 19(5), 1888–1900. Portico. https://doi.org/10.1002/alz.12817
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Morrone, C. D., Raghuraman, R., Hussaini, S. A., & Yu, W. H. (2023). Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer’s disease. Molecular Neurodegeneration, 18(1). https://doi.org/10.1186/s13024-023-00617-4
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Oveisgharan, S., Yang, J., Yu, L., Burba, D., Bang, W., Tasaki, S., Grodstein, F., Wang, Y., Zhao, J., De Jager, P. L., Schneider, J. A., & Bennett, D. A. (2023). Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease. Neurology, 100(14). https://doi.org/10.1212/wnl.0000000000206833
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Honig, L. S., Kang, M. S., Lee, A. J., Reyes-Dumeyer, D., Piriz, A., Soriano, B., Franco, Y., Coronado, Z. D., Recio, P., Mejía, D. R., Medrano, M., Lantigua, R. A., Teich, A. F., Dage, J. L., & Mayeux, R. (2023). Evaluation of Plasma Biomarkers for A/T/N Classification of Alzheimer Disease Among Adults of Caribbean Hispanic Ethnicity. JAMA Network Open, 6(4), e238214. https://doi.org/10.1001/jamanetworkopen.2023.8214
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Palma‐Gudiel, H., Yu, L., Huo, Z., Yang, J., Wang, Y., Gu, T., Gao, C., De Jager, P. L., Jin, P., Bennett, D. A., & Zhao, J. (2022). Fine‐mapping and replication of EWAS loci harboring putative epigenetic alterations associated with AD neuropathology in a large collection of human brain tissue samples. Alzheimer’s & Dementia, 19(4), 1216–1226. Portico. https://doi.org/10.1002/alz.12761
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Di, X., Yin, Y., Fu, Y., Mo, Z., Lo, S.-H., DiGuiseppi, C., Eby, D. W., Hill, L., Mielenz, T. J., Strogatz, D., Kim, M., & Li, G. (2023). Detecting mild cognitive impairment and dementia in older adults using naturalistic driving data and interaction-based classification from influence score. Artificial Intelligence in Medicine, 138, 102510. https://doi.org/10.1016/j.artmed.2023.102510
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Devanand, D. P., Masurkar, A. V., & Wisniewski, T. (2023). Vigorous, regular physical exercise may slow disease progression in Alzheimer’s disease. Alzheimer’s & Dementia, 19(4), 1592–1597. Portico. https://doi.org/10.1002/alz.12946
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Rizvi, B., Sathishkumar, M., Kim, S., Márquez, F., Granger, S. J., Larson, M. S., Miranda, B. A., Hollearn, M. K., McMillan, L., Nan, B., Tustison, N. J., Lao, P. J., Brickman, A. M., Greenia, D., Corrada, M. M., Kawas, C. H., & Yassa, M. A. (2023). Posterior white matter hyperintensities are associated with reduced medial temporal lobe subregional integrity and long-term memory in older adults. NeuroImage: Clinical, 37, 103308. https://doi.org/10.1016/j.nicl.2022.103308
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Zhu, C. W., Gu, Y., Kociolek, A. J., Fernandez, K. K., Cosentino, S., & Stern, Y. (2023). Costs During the Last Five Years of Life for Patients with Clinical and Pathological Confirmed Diagnosis of Lewy Body Dementia and Alzheimer’s Disease. Journal of Alzheimer’s Disease, 92(2), 457–466. https://doi.org/10.3233/jad-221021
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Chapman, S., Rentería, M. A., Dworkin, J. D., Garriga, S. M., Barker, M. S., Avila-Rieger, J., Gonzalez, C., Joyce, J. L., Vonk, J. M. J., Soto, E., Manly, J. J., Brickman, A. M., Mayeux, R. P., & Cosentino, S. A. (2023). Association of Subjective Cognitive Decline With Progression to Dementia in a Cognitively Unimpaired Multiracial Community Sample. Neurology, 100(10). https://doi.org/10.1212/wnl.0000000000201658
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Gouveia Roque, C., Chung, K. M., McCurdy, E. P., Jagannathan, R., Randolph, L. K., Herline-Killian, K., Baleriola, J., & Hengst, U. (2023). CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer’s disease gene expression linked to neuropathology. Science Advances, 9(9). https://doi.org/10.1126/sciadv.add2671
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Yassine, H. N., Self, W., Kerman, B. E., Santoni, G., Navalpur Shanmugam, N., Abdullah, L., Golden, L. R., Fonteh, A. N., Harrington, M. G., Gräff, J., Gibson, G. E., Kalaria, R., Luchsinger, J. A., Feldman, H. H., Swerdlow, R. H., Johnson, L. A., Albensi, B. C., Zlokovic, B. V., Tanzi, R., … Bowman, G. L. (2022). Nutritional metabolism and cerebral bioenergetics in Alzheimer’s disease and related dementias. Alzheimer’s & Dementia, 19(3), 1041–1066. Portico. https://doi.org/10.1002/alz.12845
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Huie, E. Z., Escudero, A., Saito, N., Harvey, D., Nguyen, M.-L., Lucot, K. L., LaGrande, J., Mungas, D., DeCarli, C., Lamar, M., Schneider, J. A., Kapasi, A., Rissman, R. A., Teich, A. F., & Dugger, B. N. (2023). TDP-43 Pathology in the Setting of Intermediate and High Alzheimer’s Disease Neuropathologic Changes: A Preliminary Evaluation Across Ethnoracial Groups. Journal of Alzheimer’s Disease, 91(4), 1291–1301. https://doi.org/10.3233/jad-220558
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Fleming, V., Helsel, B. C., Ptomey, L. T., Rosas, H. D., Handen, B., Laymon, C., Christian, B. T., Head, E., Mapstone, M., Lai, F., Krinsky-McHale, S., Zaman, S., Ances, B. M., Lee, J. H., & Hartley, S. L. (2023). Weight Loss and Alzheimer’s Disease in Down Syndrome. Journal of Alzheimer’s Disease, 91(3), 1215–1227. https://doi.org/10.3233/jad-220865
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Vöglein, J., Franzmeier, N., Morris, J. C., Dieterich, M., McDade, E., Simons, M., Preische, O., Hofmann, A., Hassenstab, J., Benzinger, T. L., Fagan, A., Noble, J. M., Berman, S. B., Graff‐Radford, N. R., Ghetti, B., Farlow, M. R., Chhatwal, J. P., Salloway, S., … Xiong, C. (2022). Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease. Alzheimer’s & Dementia, 19(2), 632–645. Portico. https://doi.org/10.1002/alz.12684
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Lauriola, V., Brickman, A. M., Sloan, R. P., & Small, S. A. (2023). Anatomical biology guides a search for nutrients for the aging brain. Molecular Aspects of Medicine, 89, 101154. https://doi.org/10.1016/j.mam.2022.101154
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Selles, M. C., Fortuna, J. T. S., Cercato, M. C., Santos, L. E., Domett, L., Bitencourt, A. L. B., Carraro, M. F., Souza, A. S., Janickova, H., Azevedo, C. V., Campos, H. C., de Souza, J. M., Alves-Leon, S., Prado, V. F., Prado, M. A. M., Epstein, A. L., Salvetti, A., Longo, B. M., Arancio, O., … Ferreira, S. T. (2023). AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models. Molecular Therapy, 31(2), 409–419. https://doi.org/10.1016/j.ymthe.2022.11.002
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Qu, W., Jeong, A., Zhong, R., Thieschafer, J. S., Gram, A., & Li, L. (2022). Deletion of Small GTPase H-Ras Rescues Memory Deficits and Reduces Amyloid Plaque-Associated Dendritic Spine Loss in Transgenic Alzheimer’s Mice. Molecular Neurobiology, 60(2), 495–511. https://doi.org/10.1007/s12035-022-03082-0
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Petrella, J. R., Michael, A. M., Qian, M., Nwosu, A., Sneed, J., Goldberg, T. E., Devanand, D. P., & Doraiswamy, P. M. (2023). Impact of Computerized Cognitive Training on Default Mode Network Connectivity in Subjects at Risk for Alzheimer’s Disease: A 78-week Randomized Controlled Trial. Journal of Alzheimer’s Disease, 91(1), 483–494. https://doi.org/10.3233/jad-220946
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Boerwinkle, A. H., Gordon, B. A., Wisch, J., Flores, S., Henson, R. L., Butt, O. H., McKay, N., Chen, C. D., Benzinger, T. L. S., Fagan, A. M., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Rafii, M. S., O’Bryant, S., Lai, F., Rosas, H. D., Lee, J. H., … Xu, X. (2023). Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer’s disease: a cross-sectional study. The Lancet Neurology, 22(1), 55–65. https://doi.org/10.1016/s1474-4422(22)00408-2
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Turney, I. C., Lao, P. J., Rentería, M. A., Igwe, K. C., Berroa, J., Rivera, A., Benavides, A., Morales, C. D., Rizvi, B., Schupf, N., Mayeux, R., Manly, J. J., & Brickman, A. M. (2023). Brain Aging Among Racially and Ethnically Diverse Middle-Aged and Older Adults. JAMA Neurology, 80(1), 73. https://doi.org/10.1001/jamaneurol.2022.3919
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Hani Hojjati, S., Butler, T. A., Chiang, G. C., Habeck, C., RoyChoudhury, A., Feiz, F., Shteingart, J., Nayak, S., Ozoria, S., Fernández, A., Stern, Y., Luchsinger, J. A., Devanand, D. P., & Razlighi, Q. R. (2023). Distinct and joint effects of low and high levels of Aβ and tau deposition on cortical thickness. NeuroImage: Clinical, 38, 103409. https://doi.org/10.1016/j.nicl.2023.103409
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Felsky, D., Santa-Maria, I., Cosacak, M. I., French, L., Schneider, J. A., Bennett, D. A., De Jager, P. L., Kizil, C., & Tosto, G. (2023). The Caribbean-Hispanic Alzheimer’s disease brain transcriptome reveals ancestry-specific disease mechanisms. Neurobiology of Disease, 176, 105938. https://doi.org/10.1016/j.nbd.2022.105938
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Kim, Y. A., Siddiqui, T., Blaze, J., Cosacak, M. I., Winters, T., Kumar, A., Tein, E., Sproul, A. A., Teich, A. F., Bartolini, F., Akbarian, S., Kizil, C., Hargus, G., & Santa-Maria, I. (2022). RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation. Acta Neuropathologica, 145(1), 29–48. https://doi.org/10.1007/s00401-022-02511-7
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Luckett, P. H., Chen, C., Gordon, B. A., Wisch, J., Berman, S. B., Chhatwal, J. P., Cruchaga, C., Fagan, A. M., Farlow, M. R., Fox, N. C., Jucker, M., Levin, J., Masters, C. L., Mori, H., Noble, J. M., Salloway, S., Schofield, P. R., Brickman, A. M., … Brooks, W. S. (2022). Biomarker clustering in autosomal dominant Alzheimer’s disease. Alzheimer’s & Dementia, 19(1), 274–284. Portico. https://doi.org/10.1002/alz.12661
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Kulminski, A. M., Jain‐Washburn, E., Philipp, I., He, L., Loika, Y., Loiko, E., Bagley, O., Ukraintseva, S., Yashin, A., Arbeev, K., Stallard, E., Feitosa, M. F., Schupf, N., Christensen, K., & Culminskaya, I. (2022). APOE ɛ4 allele and TOMM40‐APOC1 variants jointly contribute to survival to older ages. Aging Cell, 21(12). Portico. https://doi.org/10.1111/acel.13730
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Columbia Affiliation
Vardarajan, B. N., Reyes‐Dumeyer, D., Piriz, A. L., Lantigua, R. A., Medrano, M., Rivera, D., Jiménez‐Velázquez, I. Z., Martin, E., Pericak‐Vance, M. A., Bush, W., Farrer, L., Haines, J. L., Wang, L., Leung, Y. Y., Schellenberg, G., Kukull, W., De Jager, P., Bennett, D. A., Schneider, J. A., … Mayeux, R. (2022). Progranulin mutations in clinical and neuropathological Alzheimer’s disease. Alzheimer’s & Dementia, 18(12), 2458–2467. Portico. https://doi.org/10.1002/alz.12567
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Lee, A., Kondapalli, C., Virga, D. M., Lewis, T. L., Koo, S. Y., Ashok, A., Mairet-Coello, G., Herzig, S., Foretz, M., Viollet, B., Shaw, R., Sproul, A., & Polleux, F. (2022). Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32130-5
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Gomes, P., Tzouanou, F., Skolariki, K., Vamvaka-Iakovou, A., Noguera-Ortiz, C., Tsirtsaki, K., Waites, C. L., Vlamos, P., Sousa, N., Costa-Silva, B., Kapogiannis, D., & Sotiropoulos, I. (2022). Extracellular vesicles and Alzheimer’s disease in the novel era of Precision Medicine: implications for disease progression, diagnosis and treatment. Experimental Neurology, 358, 114183. https://doi.org/10.1016/j.expneurol.2022.114183
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Priemer, D. S., Rhodes, C. H., Karlovich, E., Perl, D. P., & Goldman, J. E. (2022). Aβ Deposits in the Neocortex of Adult and Infant Hypoxic Brains, Including in Cases of COVID-19. Journal of Neuropathology & Experimental Neurology, 81(12), 988–995. https://doi.org/10.1093/jnen/nlac095
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Mielke, M. M., Aggarwal, N. T., Vila‐Castelar, C., Agarwal, P., Arenaza‐Urquijo, E. M., Brett, B., Brugulat‐Serrat, A., DuBose, L. E., Eikelboom, W. S., Flatt, J., Foldi, N. S., Franzen, S., Gilsanz, P., Li, W., McManus, A. J., van Lent, D. M., Milani, S. A., Shaaban, C. E., … Stites, S. D. (2022). Consideration of sex and gender in Alzheimer’s disease and related disorders from a global perspective. Alzheimer’s & Dementia, 18(12), 2707–2724. Portico. https://doi.org/10.1002/alz.12662
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Schoemaker, D., Zanon Zotin, M. C., Chen, K., Igwe, K. C., Vila-Castelar, C., Martinez, J., Baena, A., Fox-Fuller, J. T., Lopera, F., Reiman, E. M., Brickman, A. M., & Quiroz, Y. T. (2022). White matter hyperintensities are a prominent feature of autosomal dominant Alzheimer’s disease that emerge prior to dementia. Alzheimer’s Research & Therapy, 14(1). https://doi.org/10.1186/s13195-022-01030-7
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Luquez, T., Gaur, P., Kosater, I. M., Lam, M., Lee, D. I., Mares, J., Paryani, F., Yadav, A., & Menon, V. (2022). Cell type-specific changes identified by single-cell transcriptomics in Alzheimer’s disease. Genome Medicine, 14(1). https://doi.org/10.1186/s13073-022-01136-5
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Siddiqui, T., Celikkaya, H., Atasavum, Z. T., Popova, S., Freudenberg, U., Werner, C., & Kizil, C. (2022). Three-Dimensional Biohybrid StarPEG–Heparin Hydrogel Cultures for Modeling Human Neuronal Development and Alzheimer’s Disease Pathology. Alzheimer’s Disease, 159–170. https://doi.org/10.1007/978-1-0716-2655-9_8
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Tropea, M. R., Gulisano, W., Vacanti, V., Arancio, O., Puzzo, D., & Palmeri, A. (2022). Nitric oxide/cGMP/CREB pathway and amyloid-beta crosstalk: From physiology to Alzheimer’s disease. Free Radical Biology and Medicine, 193, 657–668. https://doi.org/10.1016/j.freeradbiomed.2022.11.022
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Iturria-Medina, Y., Adewale, Q., Khan, A. F., Ducharme, S., Rosa-Neto, P., O’Donnell, K., Petyuk, V. A., Gauthier, S., De Jager, P. L., Breitner, J., & Bennett, D. A. (2022). Unified epigenomic, transcriptomic, proteomic, and metabolomic taxonomy of Alzheimer’s disease progression and heterogeneity. Science Advances, 8(46). https://doi.org/10.1126/sciadv.abo6764
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Yu, L., Hsieh, Y.-C., Pearse, R. V., Wang, Y., Petyuk, V. A., Schneider, J. A., Buchman, A. S., Seyfried, N. T., De Jager, P. L., Young-Pearse, T. L., & Bennett, D. A. (2022). Association of AK4 Protein From Stem Cell–Derived Neurons With Cognitive Reserve. Neurology, 99(20). https://doi.org/10.1212/wnl.0000000000201120
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Ostrowitzki, S., Bittner, T., Sink, K. M., Mackey, H., Rabe, C., Honig, L. S., Cassetta, E., Woodward, M., Boada, M., van Dyck, C. H., Grimmer, T., Selkoe, D. J., Schneider, A., Blondeau, K., Hu, N., Quartino, A., Clayton, D., Dolton, M., Dang, Y., … Doody, R. S. (2022). Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease. JAMA Neurology, 79(11), 1113. https://doi.org/10.1001/jamaneurol.2022.2909
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Pan, X., Zhang, D., Heo, J. H., Park, C., Li, G., Dengler-Crish, C. M., Li, Y., Gu, Y., Young, H. N., Lavender, D. L., & Shi, L. (2022). Antihypertensive Use and the Risk of Alzheimer’s Disease and Related Dementias among Older Adults in the USA. Drugs & Aging, 39(11), 875–886. https://doi.org/10.1007/s40266-022-00981-8
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Joseph‐Mathurin, N., Llibre‐Guerra, J. J., Li, Y., McCullough, A. A., Hofmann, C., Wojtowicz, J., Park, E., Wang, G., Preboske, G. M., Wang, Q., Gordon, B. A., Chen, C. D., Flores, S., Aggarwal, N. T., Berman, S. B., Bird, T. D., Black, S. E., Borowski, B., … Brooks, W. S. (2022). Amyloid‐Related Imaging Abnormalities in the DIAN‐TU‐001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease. Annals of Neurology, 92(5), 729–744. Portico. https://doi.org/10.1002/ana.26511
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