A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability: the MET-FINGER randomised controlled trial protocol

Barbera, M., Lehtisalo, J., Perera, D., Aspö, M., Cross, M., De Jager Loots, C. A., Falaschetti, E., Friel, N., Luchsinger, J. A., Gavelin, H. M., Peltonen, M., Price, G., Neely, A. S., Thunborg, C., Tuomilehto, J., Mangialasche, F., Middleton, L., Ngandu, T., … Solomon, A. (2024). A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability: the MET-FINGER randomised controlled trial protocol. Alzheimer’s Research & Therapy, 16(1). https://doi.org/10.1186/s13195-023-01355-x
Authors:
Mariagnese Barbera
Jenni Lehtisalo
Dinithi Perera
Malin Aspö
Mary Cross
Celeste A. de Jager Loots
Emanuela Falaschetti
Naomi Friel
José A. Luchsinger
Hanna Malmberg Gavelin
Markku Peltonen
Geraint Price
Anna Stigsdotter Neely
Charlotta Thunborg
Jaakko Tuomilehto
Francesca Mangialasche
Lefkos Middleton
Tiia Ngandu
Alina Solomon
Miia Kivipelto
Seliat Adebanke Adeleke
Clara Arvidsson
I Barton
M. J. Le Bas
Katrina Cosby
Jennifer Crispin
Lucy Helen Dunn
Margarita Durkina
Ottilia Elebring
Jamie Ford
Parthenia Giannakopoulou
Hanne Gilkes
Hannah Graham
Göran Hagman
Ruby Hall
Helena Hallinder
Arzish Haqqee
Maris Hartmanis
Katri Hemiö
Zuzana Ištvánfyová
Dimitra Kafetsouli
Kristina Lakey
Saara Lehtimäki
Lotta Lindström
Peter Macdonald
Anna‐Liisa Mäkelä
Stefan McGinn-Summers
Carolina Meius
Arslan Mirza
Christine Oesterling
Juhani Ojala
Abdulwarrith Olawale
Isabela Ramanath
Hanna-Maria Roitto
Bilal Sahib
Shonella Singh
Maria Sundell
Shannon L. Stark
Devika Tharumaratnam
Kerttu Uusimäki
Johanna Vaarala
Helena Voutilainen
Jessica Åsander
Affiliated Authors:
José A. Luchsinger
Columbia Affiliation:
Subjects:
Alzheimer Disease (MeSH)
Cognitive Dysfunction (MeSH)
Diabetes Mellitus, Type 2 (MeSH)
Metformin (MeSH)
Effects of Ketogenic Diet on Health (OpenAlex Topic)
Diagnosis and Management of Alzheimer's Disease (OpenAlex Topic)
Role of AMP-Activated Protein Kinase in Cellular Metabolism (OpenAlex Topic)
Author Keywords:
alzheimer’s
apoe
cognitive impairment
dementia prevention
drug repurposing
lifestyle intervention
lifestyle-drug combination therapy
metformin
world-wide fingers
alzheimer's
elink
Publication Type:
Article
Unique ID:
10.1186/s13195-023-01355-x
PMID:
38297399
DOI:
10.1186/s13195-023-01355-x
Journal:
Alzheimer's Research and Therapy
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
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Record Created: