Mangione, R. M., Pierce, S., Zheng, M., Martin, R. M., Goncalves, C., Kumar, A., Scaglione, S., de Sousa Morgado, C., Penzo, A., Lancrey, A., Reid, R. J. D., Lautier, O., Gaillard, P.-H., Stirling, P. C., de Almeida, S. F., Rothstein, R., & Palancade, B. (2025). DNA lesions can frequently precede DNA:RNA hybrid accumulation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57588-x

Ibarra-Arellano, M. A., Caprio, L. A., Hada, A., Stotzem, N., Cai, L. L., Shah, S. B., Walsh, Z. H., Melms, J. C., Wünneman, F., Bestak, K., Mansaray, I., Izar, B., & Schapiro, D. (2025). micronuclAI enables automated quantification of micronuclei for assessment of chromosomal instability. Communications Biology, 8(1). https://doi.org/10.1038/s42003-025-07796-4

Smith, T. L., Ryan, T. L., Escalona, M. B., Shuryak, I. E., & Balajee, A. S. (2024). Application of FISH based G2-PCC assay for the cytogenetic assessment of high radiation dose exposures: Potential implications for rapid triage biodosimetry. PLOS ONE, 19(10), e0312564. https://doi.org/10.1371/journal.pone.0312564

Bellutti, L., Macaisne, N., El Mossadeq, L., Ganeswaran, T., Canman, J. C., & Dumont, J. (2024). Regulation of outer kinetochore assembly during meiosis I and II by CENP-A and KNL-2/M18BP1 in C. elegans oocytes. Current Biology, 34(21), 4853-4868.e6. https://doi.org/10.1016/j.cub.2024.09.004

Mackay, H. L., Stone, H. R., Ronson, G. E., Ellis, K., Lanz, A., Aghabi, Y., Walker, A. K., Starowicz, K., Garvin, A. J., Van Eijk, P., Koestler, S. A., Anthony, E. J., Piberger, A. L., Chauhan, A. S., Conway-Thomas, P., Vaitsiankova, A., Vijayendran, S., Beesley, J. F., Petermann, E., … Morris, J. R. (2024). USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52250-4

Jeon, Y., Lu, Y., Ferrari, M. M., Channagiri, T., Xu, P., Meers, C., Zhang, Y., Balachander, S., Park, V. S., Marsili, S., Pursell, Z. F., Jonoska, N., & Storici, F. (2024). RNA-mediated double-strand break repair by end-joining mechanisms. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-51457-9

Royba, E., Shuryak, I., Ponnaiya, B., Repin, M., Pampou, S., Karan, C., Turner, H., Garty, G., & Brenner, D. J. (2024). Multiwell-based G0-PCC assay for radiation biodosimetry. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-69243-4

Tai, Y., Chow, A., Han, S., Coker, C., Ma, W., Gu, Y., Estrada Navarro, V., Kandpal, M., Hibshoosh, H., Kalinsky, K., Manova-Todorova, K., Safonov, A., Walsh, E. M., Robson, M., Norton, L., Baer, R., Merghoub, T., Biswas, A. K., & Acharyya, S. (2024). FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer. EMBO Molecular Medicine, 16(8), 1957–1980. https://doi.org/10.1038/s44321-024-00094-2

Galanti, L., Peritore, M., Gnügge, R., Cannavo, E., Heipke, J., Palumbieri, M. D., Steigenberger, B., Symington, L. S., Cejka, P., & Pfander, B. (2024). Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-46951-z

Georgieva, D., Wang, N., Taglialatela, A., Jerabek, S., Reczek, C. R., Lim, P. X., Sung, J., Du, Q., Horiguchi, M., Jasin, M., Ciccia, A., Baer, R., & Egli, D. (2024). BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks. Cell Reports, 43(4), 114006. https://doi.org/10.1016/j.celrep.2024.114006

Fang, Y., Hua, X., Shan, C.-M., Toda, T., Qiao, F., Zhang, Z., & Jia, S. (2024). Coordination of histone chaperones for parental histone segregation and epigenetic inheritance. Genes & Development, 38(3–4), 189–204. https://doi.org/10.1101/gad.351278.123

Kanagaraj, K., Phillippi, M. A., Narayan, P., Szolc, B., Perrier, J. R., McLane, A., Wolden, S. L., Barker, C. A., Wang, Q., Amundson, S. A., Brenner, D. J., & Turner, H. C. (2023). Assessment of Micronuclei Frequency in the Peripheral Blood of Adult and Pediatric Patients Receiving Fractionated Total Body Irradiation. Cytogenetic and Genome Research, 163(3–4), 121–130. Portico. https://doi.org/10.1159/000534433

Beaton-Green, L. A., Mayenburg, J. M., Marro, L., Hassan, E. M., Cuadros Sanchez, S., Darwish, R., Lachapelle, S., Adam, N., Burtt, J. J., Van Den Hanenberg, C., Rodrigues, M. A., Wang, Q., Brenner, D. J., Turner, H. C., & Wilkins, R. C. (2023). Application of the Cytokinesis-Block Micronucleus Assay for High-Dose Exposures Using Imaging Flow Cytometry. Cytogenetic and Genome Research, 163(3–4), 131–142. Portico. https://doi.org/10.1159/000532124

Chen, T. X., Casey, H. L., Lin, C.-Y. R., Boyle, T. A., Schmahmann, J. D., L’Italien, G. J., Kuo, S.-H., & Gomez, C. M. (2024). Early-Life Social Determinants of SCA6 Age at Onset, Severity, and Progression. The Cerebellum, 23(4), 1449–1456. https://doi.org/10.1007/s12311-023-01655-w

Giacomini, G., Piquet, S., Chevallier, O., Dabin, J., Bai, S.-K., Kim, B., Siddaway, R., Raught, B., Coyaud, E., Shan, C.-M., Reid, R. J. D., Toda, T., Rothstein, R., Barra, V., Wilhelm, T., Hamadat, S., Bertin, C., Crane, A., Dubois, F., … Polo, S. E. (2024). Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors. Nucleic Acids Research, 52(5), 2372–2388. https://doi.org/10.1093/nar/gkad1257

Wu-Baer, F., Wong, M., Tschoe, L., Lin, C.-S., Jiang, W., Zha, S., & Baer, R. (2023). ATM/ATR Phosphorylation of CtIP on Its Conserved Sae2-like Domain Is Required for Genotoxin-Induced DNA Resection but Dispensable for Animal Development. Cells, 12(23), 2762. https://doi.org/10.3390/cells12232762

Al-Zain, A. M., Nester, M. R., Ahmed, I., & Symington, L. S. (2023). Double-strand breaks induce inverted duplication chromosome rearrangements by a DNA polymerase δ-dependent mechanism. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-42640-5

Baker, B. H., Zhang, S., Simon, J. M., McLarnan, S. M., Chung, W. K., & Pearson, B. L. (2023). Environmental carcinogens disproportionally mutate genes implicated in neurodevelopmental disorders. Frontiers in Neuroscience, 17. https://doi.org/10.3389/fnins.2023.1106573

Shao, Z., Lee, B. J., Zhang, H., Lin, X., Li, C., Jiang, W., Chirathivat, N., Gershik, S., Shen, M. M., Baer, R., & Zha, S. (2023). Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner. Proceedings of the National Academy of Sciences, 120(31). https://doi.org/10.1073/pnas.2301972120

Schvartzman, J.-M., Forsyth, G., Walch, H., Chatila, W., Taglialatela, A., Lee, B. J., Zhu, X., Gershik, S., Cimino, F. V., Santella, A., Menghrajani, K., Ciccia, A., Koche, R., Sánchez-Vega, F., Zha, S., & Thompson, C. B. (2023). Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination. Molecular Cell, 83(13), 2347-2356.e8. https://doi.org/10.1016/j.molcel.2023.05.026

Kimble, M. T., Johnson, M. J., Nester, M. R., & Symington, L. S. (2023). Long-range DNA end resection supports homologous recombination by checkpoint activation rather than extensive homology generation. ELife, 12. CLOCKSS. https://doi.org/10.7554/elife.84322

Gnügge, R., Reginato, G., Cejka, P., & Symington, L. S. (2023). Sequence and chromatin features guide DNA double-strand break resection initiation. Molecular Cell, 83(8), 1237-1250.e15. https://doi.org/10.1016/j.molcel.2023.02.010

Shuryak, I., Royba, E., Repin, M., Turner, H. C., Garty, G., Deoli, N., & Brenner, D. J. (2022). A machine learning method for improving the accuracy of radiation biodosimetry by combining data from the dicentric chromosomes and micronucleus assays. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-25453-2

Xu, X., Duan, S., Hua, X., Li, Z., He, R., & Zhang, Z. (2022). Stable inheritance of H3.3-containing nucleosomes during mitotic cell divisions. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30298-4

Marie, L., & Symington, L. S. (2022). Mechanism for inverted-repeat recombination induced by a replication fork barrier. Nature Communications, 13(1). https://doi.org/10.1038/s41467-021-27443-w

Xu, X., Hua, X., Brown, K., Ren, X., & Zhang, Z. (2022). Mcm2 promotes stem cell differentiation via its ability to bind H3-H4. ELife, 11. CLOCKSS. https://doi.org/10.7554/elife.80917

Conte, M. I., Poli, M. C., Taglialatela, A., Leuzzi, G., Chinn, I. K., Salinas, S. A., Rey-Jurado, E., Olivares, N., Veramendi-Espinoza, L., Ciccia, A., Lupski, J. R., Aldave Becerra, J. C., Mace, E. M., & Orange, J. S. (2022). Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia. JCI Insight, 7(21). https://doi.org/10.1172/jci.insight.154948

Wang, Z., Wang, J., Zhao, H., Zhao, T., Chen, Y., Jiang, M., Zhang, S., Wei, Y., Zhang, J., Zhou, Y., Shi, S., Fu, Z., Yang, Y., Zhang, Y., Yang, L., Que, J., & Liu, K. (2022). Targeting the SOX2/PARP1 complex to intervene in the growth of esophageal squamous cell carcinoma. Biomedicine & Pharmacotherapy, 153, 113309. https://doi.org/10.1016/j.biopha.2022.113309

Halder, S., Ranjha, L., Taglialatela, A., Ciccia, A., & Cejka, P. (2022). Strand annealing and motor driven activities of SMARCAL1 and ZRANB3 are stimulated by RAD51 and the paralog complex. Nucleic Acids Research, 50(14), 8008–8022. https://doi.org/10.1093/nar/gkac583

Alvarez, S., da Silva Almeida, A. C., Albero, R., Biswas, M., Barreto-Galvez, A., Gunning, T. S., Shaikh, A., Aparicio, T., Wendorff, A., Piovan, E., Van Vlierberghe, P., Gygi, S., Gautier, J., Madireddy, A., & A. Ferrando, A. (2022). Functional mapping of PHF6 complexes in chromatin remodeling, replication dynamics, and DNA repair. Blood, 139(23), 3418–3429. https://doi.org/10.1182/blood.2021014103

Park, D., Gharghabi, M., Reczek, C. R., Plow, R., Yungvirt, C., Aldaz, C. M., & Huebner, K. (2022). Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice. International Journal of Molecular Sciences, 23(7), 3729. https://doi.org/10.3390/ijms23073729

Martinez-Pastor, B., Silveira, G. G., Clarke, T. L., Chung, D., Gu, Y., Cosentino, C., Davidow, L. S., Mata, G., Hassanieh, S., Salsman, J., Ciccia, A., Bae, N., Bedford, M. T., Megias, D., Rubin, L. L., Efeyan, A., Dellaire, G., & Mostoslavsky, R. (2021). Assessing kinetics and recruitment of DNA repair factors using high content screens. Cell Reports, 37(13), 110176. https://doi.org/10.1016/j.celrep.2021.110176

Rousová, D., Nivsarkar, V., Altmannova, V., Raina, V. B., Funk, S. K., Liedtke, D., Janning, P., Müller, F., Reichle, H., Vader, G., & Weir, J. R. (2021). Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation. ELife, 10. CLOCKSS. https://doi.org/10.7554/elife.72330