hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan

Adam, N., Yang, Y., Djamshidi, M., Seifan, S., Ting, N. S. Y., Glover, J., Touret, N., Gordon, P. M. K., Vineetha Warriyar, K. V., Krowicki, H., Garcia, C. K., Savage, S. A., Goodarzi, A. A., Baird, D. M., Beattie, T. L., & Riabowol, K. (2025). hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan. Aging Cell. Portico. https://doi.org/10.1111/acel.70105
Authors:
Nancy Adam
Yang Yang
Mahbod Djamshidi
Sara Seifan
Nicholas S Y Ting
Joel Glover
Nicolas Touret
Paul M K Gordon
K V Vineetha Warriyar
Hokan Krowicki
Christine Kim Garcia
Sharon A Savage
Aaron A Goodarzi
Duncan M Baird
Tara L Beattie
Karl Riabowol
Affiliated Authors:
Christine Kim Garcia
Columbia Affiliation:
Subjects:
Cellular Senescence and Aging-Related Diseases (OpenAlex Topic)
Molecular Mechanisms of DNA Damage Response (OpenAlex Topic)
Genome Evolution and Polyploidy in Plants (OpenAlex Topic)
Author Keywords:
trf2 stabilization
htert noncanonical activity
senescence
telomere clustering
telomere compaction
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Publication Type:
Article
Unique ID:
10.1111/acel.70105
PMID:
40371663
DOI:
10.1111/acel.70105
Journal:
Aging Cell
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View OpenAlex Record

Record Created: