FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer

Tai, Y., Chow, A., Han, S., Coker, C., Ma, W., Gu, Y., Estrada Navarro, V., Kandpal, M., Hibshoosh, H., Kalinsky, K., Manova-Todorova, K., Safonov, A., Walsh, E. M., Robson, M., Norton, L., Baer, R., Merghoub, T., Biswas, A. K., & Acharyya, S. (2024). FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer. EMBO Molecular Medicine, 16(8), 1957–1980. https://doi.org/10.1038/s44321-024-00094-2
Authors:
Courtney Coker
Angela Chow
Sang Hoon Han
Courtney Coker
Wanchao Ma
Yifan Gu
V. Navarro
Manoj Kandpal
Hanina Hibshoosh
Kevin Kalinsky
Katia Manova–Todorova
Anton Safonov
Elaine M. Walsh
Mark E. Robson
Larry Norton
Richard Baer
Taha Merghoub
A. Biswas
Swarnali Acharyya
Affiliated Authors:
Courtney Coker
Angela Chow
Sang Hoon Han
Courtney Coker
Wanchao Ma
Yifan Gu
Hanina Hibshoosh
Richard Baer
A. Biswas
Swarnali Acharyya
Columbia Affiliation:
Subjects:
Poly(ADP-ribose) Polymerase Inhibitors (MeSH)
Breast Neoplasms (MeSH)
Drug Resistance, Neoplasm (MeSH)
Vascular Endothelial Growth Factor Receptor-1 (MeSH)
Poly(ADP-ribose) Polymerase Inhibition in Cancer Therapy (OpenAlex Topic)
Molecular Mechanisms of DNA Damage Response (OpenAlex Topic)
Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins (OpenAlex Topic)
Author Keywords:
flt1
vegfr1
breast cancer
parp-inhibitor-resistance
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Publication Type:
Article
Unique ID:
10.1038/s44321-024-00094-2
PMID:
38956205
DOI:
10.1038/s44321-024-00094-2
Journal:
EMBO Molecular Medicine
Publication Date:
Data Source:
OpenAlex
Source Link:
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