Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice

Park, D., Gharghabi, M., Reczek, C. R., Plow, R., Yungvirt, C., Aldaz, C. M., & Huebner, K. (2022). Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice. International Journal of Molecular Sciences, 23(7), 3729. https://doi.org/10.3390/ijms23073729
Authors:
Dongju Park
Mehdi Gharghabi
Colleen R Reczek
Rebecca Plow
Charles Yungvirt
C Marcelo Aldaz
Kay Huebner
Affiliated Authors:
Colleen R Reczek
Columbia Affiliation:
Subjects:
Molecular Mechanisms of DNA Damage Response (OpenAlex Topic)
Poly(ADP-ribose) Polymerase Inhibition in Cancer Therapy (OpenAlex Topic)
Regulation of Chromatin Structure and Function (OpenAlex Topic)
BRCA1 Protein (MeSH)
DNA Breaks, Double-Stranded (MeSH)
WW Domain-Containing Oxidoreductase (MeSH)
Author Keywords:
end-resection at dsbs
wwox deficiency
chk2 inhibition
ir and platinum treatment resistance
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Publication Type:
Article
Unique ID:
10.3390/ijms23073729
PMID:
35409089
DOI:
10.3390/ijms23073729
Journal:
International Journal of Molecular Sciences
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: