BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks

Georgieva, D., Wang, N., Taglialatela, A., Jerabek, S., Reczek, C. R., Lim, P. X., Sung, J., Du, Q., Horiguchi, M., Jasin, M., Ciccia, A., Baer, R., & Egli, D. (2024). BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks. Cell Reports, 43(4), 114006. https://doi.org/10.1016/j.celrep.2024.114006
Authors:
Daniela Georgieva
Ning Wang
Angelo Taglialatela
Stepan Jerabek
Colleen R Reczek
Pei Xin Lim
Julie Sung
Qian Du
Michiko Horiguchi
Maria Jasin
Alberto Ciccia
Richard Baer
Dieter Egli
Affiliated Authors:
Daniela Georgieva
Ning Wang
Angelo Taglialatela
Stepan Jerabek
Colleen R Reczek
Julie Sung
Qian Du
Michiko Horiguchi
Alberto Ciccia
Richard Baer
Dieter Egli
Columbia Affiliation:
Subjects:
Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins (OpenAlex Topic)
Induction and Differentiation of Pluripotent Stem Cells (OpenAlex Topic)
Molecular Mechanisms of DNA Damage Response (OpenAlex Topic)
BRCA1 Protein (MeSH)
Cellular Reprogramming (MeSH)
DNA Breaks, Double-Stranded (MeSH)
DNA Repair (MeSH)
Tumor Suppressor p53-Binding Protein 1 (MeSH)
Author Keywords:
brca1
brca2
cp: molecular biology
double-strand break
pluripotency
replication gap suppression
replication stress
somatic cell reprogramming
stalled replication fork
elink
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2024.114006
PMID:
38554279
DOI:
10.1016/j.celrep.2024.114006
Journal:
Cell Reports
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View OpenAlex Record
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View Web of Science Record

Record Created: