Mitochondrial Dynamics and Reactive Oxygen Species Regulation

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Sturm, G., Monzel, A. S., Karan, K. R., Michelson, J., Ware, S. A., Cardenas, A., Lin, J., Bris, C., Santhanam, B., Murphy, M. P., Levine, M. E., Horvath, S., Belsky, D. W., Wang, S., Procaccio, V., Kaufman, B. A., Hirano, M., & Picard, M. (2022). A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations. Scientific Data, 9(1). https://doi.org/10.1038/s41597-022-01852-y
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Hickman, R. A., Faust, P. L., Marder, K., Yamamoto, A., & Vonsattel, J.-P. (2022). The distribution and density of Huntingtin inclusions across the Huntington disease neocortex: regional correlations with Huntingtin repeat expansion independent of pathologic grade. Acta Neuropathologica Communications, 10(1). https://doi.org/10.1186/s40478-022-01364-1
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Barajas, M. B., Brunner, S. D., Wang, A., Griffiths, K. K., & Levy, R. J. (2022). Propofol toxicity in the developing mouse heart mitochondria. Pediatric Research, 92(5), 1341–1349. https://doi.org/10.1038/s41390-022-01985-1
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Oh, M., Hasanain, M., Migliozzi, S., Garofano, L., D’Angelo, F., Stefano, A. L. D., Lerond, J., Sarkaria, J., Ceccarelli, M., Sanson, M., Lasorella, A., & Iavarone, A. (2022). EXTH-21. DEVELOPMENT OF THERAPEUTIC STRATEGIES BY PATHWAY-BASED MULTI-OMICS APPROACH AND MASTER KINASE ANALYSIS IN GLIOBLASTOMA MULTIFORME. Neuro-Oncology, 24(Supplement_7), vii214–vii214. https://doi.org/10.1093/neuonc/noac209.820
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Mnatsakanyan, N., Park, H.-A., Wu, J., He, X., Llaguno, M. C., Latta, M., Miranda, P., Murtishi, B., Graham, M., Weber, J., Levy, R. J., Pavlov, E. V., & Jonas, E. A. (2022). Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex. Cell Death & Differentiation, 29(9), 1874–1887. https://doi.org/10.1038/s41418-022-00972-7
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Shintaku, J., Pernice, W. M., Eyaid, W., GC, J. B., Brown, Z. P., Juanola-Falgarona, M., Torres-Torronteras, J., Sommerville, E. W., Hellebrekers, D. M. E. I., Blakely, E. L., Donaldson, A., van de Laar, I., Leu, C.-S., Marti, R., Frank, J., Tanji, K., Koolen, D. A., Rodenburg, R. J., Chinnery, P. F., … Hirano, M. (2022). RRM1 variants cause a mitochondrial DNA maintenance disorder via impaired de novo nucleotide synthesis. Journal of Clinical Investigation, 132(13). https://doi.org/10.1172/jci145660
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Pannkuk, E. L., Laiakis, E. C., Garty, G., Bansal, S., Ponnaiya, B., Wu, X., Ghandhi, S. A., Amundson, S. A., Brenner, D. J., & Fornace, A. J. (2022). Biofluid Metabolomics and Lipidomics of Mice Exposed to External Very High-Dose Rate Radiation. Metabolites, 12(6), 520. https://doi.org/10.3390/metabo12060520
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Columbia Affiliation
Trumpff, C., Owusu-Ansah, E., Klein, H.-U., Lee, A. J., Petyuk, V., Wingo, T. S., Wingo, A. P., Thambisetty, M., Ferrucci, L., Seyfried, N. T., Bennett, D. A., De Jager, P. L., & Picard, M. (2022). Mitochondrial respiratory chain protein co-regulation in the human brain. Heliyon, 8(5), e09353. https://doi.org/10.1016/j.heliyon.2022.e09353
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López-Gómez, C., Cámara, Y., Hirano, M., & Martí, R. (2022). 232nd ENMC international workshop: Recommendations for treatment of mitochondrial DNA maintenance disorders. 16 – 18 June 2017, Heemskerk, The Netherlands. Neuromuscular Disorders, 32(7), 609–620. https://doi.org/10.1016/j.nmd.2022.05.008
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Murari, A., Goparaju, N. S. V., Rhooms, S.-K., Hossain, K. F. B., Liang, F. G., Garcia, C. J., Osei, C., Liu, T., Li, H., Kitsis, R. N., Patel, R., & Owusu-Ansah, E. (2022). IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system. Science Advances, 8(19). https://doi.org/10.1126/sciadv.abl8716
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Willcox, J. A. L., Geiger, J. T., Morton, S. U., McKean, D., Quiat, D., Gorham, J. M., Tai, A. C., DePalma, S., Bernstein, D., Brueckner, M., Chung, W. K., Giardini, A., Goldmuntz, E., Kaltman, J. R., Kim, R., Newburger, J. W., Shen, Y., Srivastava, D., Tristani-Firouzi, M., … Seidman, C. E. (2022). Neither cardiac mitochondrial DNA variation nor copy number contribute to congenital heart disease risk. The American Journal of Human Genetics, 109(5), 961–966. https://doi.org/10.1016/j.ajhg.2022.03.011
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Chang, Y.-H., Kang, E. Y.-C., Liu, P.-K., Levi, S. R., Wang, H.-H., Tseng, Y.-J., Seo, G. H., Lee, H., Yeh, L.-K., Chen, K.-J., Wu, W.-C., Lai, C.-C., Liu, L., & Wang, N.-K. (2022). Photoreceptor Manifestations of Primary Mitochondrial Optic Nerve Disorders. Investigative Opthalmology & Visual Science, 63(5), 5. https://doi.org/10.1167/iovs.63.5.5
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Giordano, E., Tesone, A., Trinchese, G., Dentice, M., Mollica, M. P., Diano, S., & Menale, C. (2022). Mitochondria dynamics and function dictate osteoblast metabolism in response to nutrients. Bone Reports, 16, 101541. https://doi.org/10.1016/j.bonr.2022.101541
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Çoku, J., Booth, D. M., Skoda, J., Pedrotty, M. C., Vogel, J., Liu, K., Vu, A., Carpenter, E. L., Ye, J. C., Chen, M. A., Dunbar, P., Scadden, E., Yun, T. D., Nakamaru‐Ogiso, E., Area‐Gomez, E., Li, Y., Goldsmith, K. C., Reynolds, C. P., Hajnoczky, G., & Hogarty, M. D. (2022). Reduced ER–mitochondria connectivity promotes neuroblastoma multidrug resistance. The EMBO Journal, 41(8). Portico. https://doi.org/10.15252/embj.2021108272
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Brown, A.-L., Wilkins, O. G., Keuss, M. J., Hill, S. E., Zanovello, M., Lee, W. C., Bampton, A., Lee, F. C. Y., Masino, L., Qi, Y. A., Bryce-Smith, S., Gatt, A., Hallegger, M., Fagegaltier, D., Phatnani, H., Phatnani, H., Kwan, J., Sareen, D., … Fratta, P. (2022). TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A. Nature, 603(7899), 131–137. https://doi.org/10.1038/s41586-022-04436-3
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Longchamps, R. J., Yang, S. Y., Castellani, C. A., Shi, W., Lane, J., Grove, M. L., Bartz, T. M., Sarnowski, C., Liu, C., Burrows, K., Guyatt, A. L., Gaunt, T. R., Kacprowski, T., Yang, J., De Jager, P. L., Yu, L., Bergman, A., Xia, R., Fornage, M., … Arking, D. E. (2021). Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation. Human Genetics, 141(1), 127–146. https://doi.org/10.1007/s00439-021-02394-w
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Zanou, N., Dridi, H., Reiken, S., Imamura de Lima, T., Donnelly, C., De Marchi, U., Ferrini, M., Vidal, J., Sittenfeld, L., Feige, J. N., Garcia-Roves, P. M., Lopez-Mejia, I. C., Marks, A. R., Auwerx, J., Kayser, B., & Place, N. (2021). Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-27422-1
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Yap, Z. Y., Efthymiou, S., Seiffert, S., Vargas Parra, K., Lee, S., Nasca, A., Maroofian, R., Schrauwen, I., Pendziwiat, M., Jung, S., Bhoj, E., Striano, P., Mankad, K., Vona, B., Cuddapah, S., Wagner, A., Alvi, J. R., Davoudi-Dehaghani, E., Fallah, M.-S., … Yoon, W. H. (2021). Bi-allelic variants in OGDHL cause a neurodevelopmental spectrum disease featuring epilepsy, hearing loss, visual impairment, and ataxia. The American Journal of Human Genetics, 108(12), 2368–2384. https://doi.org/10.1016/j.ajhg.2021.11.003
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Fernström, J., Mellon, S. H., McGill, M. A., Picard, M., Reus, V. I., Hough, C. M., Lin, J., Epel, E. S., Wolkowitz, O. M., & Lindqvist, D. (2021). Blood-based mitochondrial respiratory chain function in major depression. Translational Psychiatry, 11(1). https://doi.org/10.1038/s41398-021-01723-x
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Ansari, F., Yoval-Sánchez, B., Niatsetskaya, Z., Sosunov, S., Stepanova, A., Garcia, C., Owusu-Ansah, E., Ten, V., Wittig, I., & Galkin, A. (2021). Quantification of NADH:ubiquinone oxidoreductase (complex I) content in biological samples. Journal of Biological Chemistry, 297(4), 101204. https://doi.org/10.1016/j.jbc.2021.101204
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