Ma, F., Longo, M., Meroni, M., Bhattacharya, D., Paolini, E., Mughal, S., Hussain, S., Anand, S. K., Gupta, N., Zhu, Y., Navarro-Corcuera, A., Li, K., Prakash, S., Cogliati, B., Wang, S., Huang, X., Wang, X., Yurdagul, A., Rom, O., … Cai, B. (2025). EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis. Cell Metabolism. https://doi.org/10.1016/j.cmet.2025.01.020

Agarwal, H., Wang, Y., Tinsley, B., Wang, X., & Ozcan, L. (2025). RAP1A suppresses hepatic steatosis by regulating amino acid-mediated mTORC1 activation. JHEP Reports, 7(4), 101303. https://doi.org/10.1016/j.jhepr.2024.101303

Liu, W., Hardaway, B. D., Kim, E., Pauli, J., Wettich, J. L., Yalcinkaya, M., Hsu, C.-C., Xiao, T., Reilly, M. P., Tabas, I., Maegdefessel, L., Schlepckow, K., Christian, H., Wang, N., & Tall, A. R. (2024). Inflammatory crosstalk impairs phagocytic receptors and aggravates atherosclerosis in clonal hematopoiesis in mice. Journal of Clinical Investigation. https://doi.org/10.1172/jci182939

Sukka, S. R., Ampomah, P. B., Darville, L. N. F., Ngai, D., Wang, X., Kuriakose, G., Xiao, Y., Shi, J., Koomen, J. M., McCusker, R. H., & Tabas, I. (2024). Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution. Nature Metabolism, 6(9), 1736–1755. https://doi.org/10.1038/s42255-024-01115-7

Yalcinkaya, M., & Tall, A. R. (2024). Genetic and epigenetic regulation of inflammasomes: Role in atherosclerosis. Atherosclerosis, 396, 118541. https://doi.org/10.1016/j.atherosclerosis.2024.118541

Ngai, D., Sukka, S. R., & Tabas, I. (2024). Crosstalk between efferocytic myeloid cells and T-cells and its relevance to atherosclerosis. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1403150

Moore, M. P., Wang, X., Kennelly, J. P., Shi, H., Ishino, Y., Kano, K., Aoki, J., Cherubini, A., Ronzoni, L., Guo, X., Chalasani, N. P., Khalid, S., Saleheen, D., Mitsche, M. A., Rotter, J. I., Yates, K. P., Valenti, L., Kono, N., Tontonoz, P., & Tabas, I. (2024). Low MBOAT7 expression, a genetic risk for MASH, promotes a profibrotic pathway involving hepatocyte TAZ upregulation. Hepatology. https://doi.org/10.1097/hep.0000000000000933

Ghooray, D. T., Xu, M., Shi, H., McClain, C. J., & Song, M. (2024). Hepatocyte-Specific Fads1 Overexpression Attenuates Western Diet-Induced Metabolic Phenotypes in a Rat Model. International Journal of Molecular Sciences, 25(9), 4836. https://doi.org/10.3390/ijms25094836

Dou, H., Wang, R., Tavallaie, M., Xiao, T., Olszewska, M., Papapetrou, E. P., Tall, A. R., & Wang, N. (2024). Hematopoietic and eosinophil-specific LNK(SH2B3) deficiency promotes eosinophilia and arterial thrombosis. Blood, 143(17), 1758–1772. https://doi.org/10.1182/blood.2023021055

Liu, W., Pircher, J., Schuermans, A., Ul Ain, Q., Zhang, Z., Honigberg, M. C., Yalcinkaya, M., Nakao, T., Pournamadri, A., Xiao, T., Hajebrahimi, M. A., Wasner, L., Stegner, D., Petzold, T., Natarajan, P., Massberg, S., Tall, A. R., Schulz, C., & Wang, N. (2024). Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk. Blood, 143(15), 1539–1550. https://doi.org/10.1182/blood.2023022260

Yalcinkaya, M., Liu, W., Xiao, T., Abramowicz, S., Wang, R., Wang, N., Westerterp, M., & Tall, A. R. (2024). Cholesterol trafficking to the ER leads to the activation of CaMKII/JNK/NLRP3 and promotes atherosclerosis. Journal of Lipid Research, 65(4), 100534. https://doi.org/10.1016/j.jlr.2024.100534

Tall, A. R., & Fidler, T. P. (2024). An epigenetic switch in macrophages promotes fibrosis in the failing heart. Nature Cardiovascular Research, 3(3), 254–255. https://doi.org/10.1038/s44161-024-00439-7

Wang, X., Zhang, L., & Dong, B. (2024). Molecular mechanisms in MASLD/MASH-related HCC. Hepatology. https://doi.org/10.1097/hep.0000000000000786

Wang, Y., Tinsley, B., Spolitu, S., Zadroga, J. A., Agarwal, H., Sarecha, A. K., & Ozcan, L. (2024). Geranylgeranyl isoprenoids and hepatic Rap1a regulate basal and statin-induced expression of PCSK9. Journal of Lipid Research, 65(3), 100515. https://doi.org/10.1016/j.jlr.2024.100515

Fidler, T. P., Dunbar, A., Kim, E., Hardaway, B., Pauli, J., Xue, C., Abramowicz, S., Xiao, T., O’Connor, K., Sachs, N., Wang, N., Maegdefessel, L., Levine, R., Reilly, M., & Tall, A. R. (2024). Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis. Nature Cardiovascular Research, 3(1), 60–75. https://doi.org/10.1038/s44161-023-00405-9

Shi, H., Moore, M. P., Wang, X., & Tabas, I. (2024). Efferocytosis in liver disease. JHEP Reports, 6(1), 100960. https://doi.org/10.1016/j.jhepr.2023.100960

Wang, X., Moore, M. P., Shi, H., Miyata, Y., Donnelly, S. K., Radiloff, D. R., & Tabas, I. (2023). Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers. Molecular Therapy - Methods & Clinical Development, 31, 101165. https://doi.org/10.1016/j.omtm.2023.101165

Yalcinkaya, M., Liu, W., Thomas, L.-A., Olszewska, M., Xiao, T., Abramowicz, S., Papapetrou, E. P., Westerterp, M., Wang, N., Tabas, I., & Tall, A. R. (2023). BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis. Circulation, 148(22), 1764–1777. https://doi.org/10.1161/circulationaha.123.065344

Agarwal, H., Tinsley, B., Sarecha, A. K., & Ozcan, L. (2023). Rap1 in the Context of PCSK9, Atherosclerosis, and Diabetes. Current Atherosclerosis Reports, 25(12), 931–937. https://doi.org/10.1007/s11883-023-01162-7

Schilperoort, M., Ngai, D., Sukka, S. R., Avrampou, K., Shi, H., & Tabas, I. (2023). The role of efferocytosis‐fueled macrophage metabolism in the resolution of inflammation. Immunological Reviews, 319(1), 65–80. Portico. https://doi.org/10.1111/imr.13214

Yu, Z., Fidler, T. P., Ruan, Y., Vlasschaert, C., Nakao, T., Uddin, M. M., Mack, T., Niroula, A., Heimlich, J. B., Zekavat, S. M., Gibson, C. J., Griffin, G. K., Wang, Y., Peloso, G. M., Heard-Costa, N., Levy, D., Vasan, R. S., Aguet, F., Ardlie, K. G., … Natarajan, P. (2023). Genetic modification of inflammation- and clonal hematopoiesis–associated cardiovascular risk. Journal of Clinical Investigation, 133(18). https://doi.org/10.1172/jci168597

Dai, W., Zhang, H., Lund, H., Zhang, Z., Castleberry, M., Rodriguez, M., Kuriakose, G., Gupta, S., Lewandowska, M., Powers, H. R., Valmiki, S., Zhu, J., Shapiro, A. D., Hussain, M. M., López, J. A., Sorci-Thomas, M. G., Silverstein, R. L., Ginsberg, H. N., Sahoo, D., … Zheng, Z. (2023). Intracellular tPA–PAI-1 interaction determines VLDL assembly in hepatocytes. Science, 381(6661). https://doi.org/10.1126/science.adh5207

Hsu, C.-C., Fidler, T. P., Kanter, J. E., Kothari, V., Kramer, F., Tang, J., Tall, A. R., & Bornfeldt, K. E. (2023). Hematopoietic NLRP3 and AIM2 Inflammasomes Promote Diabetes-Accelerated Atherosclerosis, but Increased Necrosis Is Independent of Pyroptosis. Diabetes, 72(7), 999–1011. https://doi.org/10.2337/db22-0962

Saito, Y., Yin, D., Kubota, N., Wang, X., Filliol, A., Remotti, H., Nair, A., Fazlollahi, L., Hoshida, Y., Tabas, I., Wangensteen, K. J., & Schwabe, R. F. (2023). A Therapeutically Targetable TAZ-TEAD2 Pathway Drives the Growth of Hepatocellular Carcinoma via ANLN and KIF23. Gastroenterology, 164(7), 1279–1292. https://doi.org/10.1053/j.gastro.2023.02.043

Liu, W., Yalcinkaya, M., Maestre, I. F., Olszewska, M., Ampomah, P. B., Heimlich, J. B., Wang, R., Vela, P. S., Xiao, T., Bick, A. G., Levine, R., Papapetrou, E. P., Libby, P., Tabas, I., Wang, N., & Tall, A. R. (2023). Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis. Nature Cardiovascular Research, 2(6), 572–586. https://doi.org/10.1038/s44161-023-00281-3

Tall, A. R., & Bornfeldt, K. E. (2023). Inflammasomes and Atherosclerosis: a Mixed Picture. Circulation Research, 132(11), 1505–1520. https://doi.org/10.1161/circresaha.123.321637

Yalcinkaya, M., Fotakis, P., Liu, W., Endo-Umeda, K., Dou, H., Abramowicz, S., Xiao, T., Libby, P., Wang, N., Tall, A. R., & Westerterp, M. (2022). Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion. Cardiovascular Research, 119(4), 969–981. https://doi.org/10.1093/cvr/cvac189

Moore, M. P., Wang, X., Shi, H., Meroni, M., Cherubini, A., Ronzoni, L., Parks, E. J., Ibdah, J. A., Rector, R. S., Valenti, L., Dongiovanni, P., & Tabas, I. (2023). Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH. JHEP Reports, 5(5), 100716. https://doi.org/10.1016/j.jhepr.2023.100716

Vela, P. S., Wang, R., Tran, D., Benitez, A. M., Krishnan, A., O’Connor, K., Liu, W., Kleppe, M., Bowman, R., Cai, S., Shih, A., Wang, N., Esteller, M., Bolton, K., Tall, A., & Levine, R. (2023). 3168 – TARGETING JAK1 SIGNALING FOR MOLECULAR PREVENTION IN CLONAL HEMATOPOIESIS. Experimental Hematology, 124, S133. https://doi.org/10.1016/j.exphem.2023.06.275

Shi, H., Prough, R. A., McClain, C. J., & Song, M. (2023). Different Types of Dietary Fat and Fructose Interactions Result in Distinct Metabolic Phenotypes in Male Mice. The Journal of Nutritional Biochemistry, 111, 109189. https://doi.org/10.1016/j.jnutbio.2022.109189

Garg, P. K., Tressel, W., McClelland, R. L., Criqui, M. H., Stein, J. H., Yvan-Chavret, L., Tall, A. R., & Shea, S. (2022). Cholesterol mass efflux capacity and coronary artery calcium: The Multi-Ethnic Study of Atherosclerosis. Journal of Clinical Lipidology, 16(6), 895–900. https://doi.org/10.1016/j.jacl.2022.09.004

Shi, H., Wang, X., Li, F., Gerlach, B. D., Yurdagul, A., Moore, M. P., Zeldin, S., Zhang, H., Cai, B., Zheng, Z., Valenti, L., & Tabas, I. (2022). CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis. Science Translational Medicine, 14(672). https://doi.org/10.1126/scitranslmed.abp8309

Filliol, A., Saito, Y., Nair, A., Dapito, D. H., Yu, L.-X., Ravichandra, A., Bhattacharjee, S., Affo, S., Fujiwara, N., Su, H., Sun, Q., Savage, T. M., Wilson-Kanamori, J. R., Caviglia, J. M., Chin, L., Chen, D., Wang, X., Caruso, S., Kang, J. K., … Schwabe, R. F. (2022). Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis. Nature, 610(7931), 356–365. https://doi.org/10.1038/s41586-022-05289-6

Murphy, A. J., Dragoljevic, D., Natarajan, P., & Wang, N. (2022). Hematopoiesis of Indeterminate Potential and Atherothrombotic Risk. Thrombosis and Haemostasis, 122(09), 1435–1442. CLOCKSS. https://doi.org/10.1055/a-1830-2147

Soehnlein, O., & Tall, A. R. (2022). AIMing 2 treat atherosclerosis. Nature Reviews Cardiology, 19(9), 567–568. https://doi.org/10.1038/s41569-022-00755-0

Wang, X. (2022). Challenges and opportunities in nonalcoholic steatohepatitis. Medical Review, 2(4), 328–330. https://doi.org/10.1515/mr-2022-0024

Lin, Q., Chen, O., Wise, J. P., Shi, H., Wintergerst, K. A., Cai, L., & Tan, Y. (2022). FGF1ΔHBS delays the progression of diabetic nephropathy in late-stage type 2 diabetes mouse model by alleviating renal inflammation, fibrosis, and apoptosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1868(8), 166414. https://doi.org/10.1016/j.bbadis.2022.166414

Liu, W., Östberg, N., Yalcinkaya, M., Dou, H., Endo-Umeda, K., Tang, Y., Hou, X., Xiao, T., Fidler, T. P., Abramowicz, S., Yang, Y.-G., Soehnlein, O., Tall, A. R., & Wang, N. (2022). Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis. Journal of Clinical Investigation, 132(13). https://doi.org/10.1172/jci155724

Tall, A. R., Rader, D. J., & Kastelein, J. J. P. (2022). Macular Degeneration and CETP Inhibition. JAMA Cardiology, 7(7), 774. https://doi.org/10.1001/jamacardio.2022.1276

Endo-Umeda, K., Kim, E., Thomas, D. G., Liu, W., Dou, H., Yalcinkaya, M., Abramowicz, S., Xiao, T., Antonson, P., Gustafsson, J.-Å., Makishima, M., Reilly, M. P., Wang, N., & Tall, A. R. (2022). Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 42(6), 719–731. https://doi.org/10.1161/atvbaha.122.317583

Mederacke, I., Filliol, A., Affo, S., Nair, A., Hernandez, C., Sun, Q., Hamberger, F., Brundu, F., Chen, Y., Ravichandra, A., Huebener, P., Anke, H., Shi, H., Martínez García de la Torre, R. A., Smith, J. R., Henderson, N. C., Vondran, F. W. R., Rothlin, C. V., Baehre, H., … Schwabe, R. F. (2022). The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver. Science Translational Medicine, 14(639). https://doi.org/10.1126/scitranslmed.abe5795

Han, H., Wang, Y., Curto, J., Gurrapu, S., Laudato, S., Rumandla, A., Chakraborty, G., Wang, X., Chen, H., Jiang, Y., Kumar, D., Caggiano, E. G., Capogiri, M., Zhang, B., Ji, Y., Maity, S. N., Hu, M., Bai, S., Aparicio, A. M., … Giancotti, F. G. (2022). Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis. Cell Reports, 39(1), 110595. https://doi.org/10.1016/j.celrep.2022.110595

Ampomah, P. B., Cai, B., Sukka, S. R., Gerlach, B. D., Yurdagul, A., Wang, X., Kuriakose, G., Darville, L. N. F., Sun, Y., Sidoli, S., Koomen, J. M., Tall, A. R., & Tabas, I. (2022). Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution. Nature Metabolism, 4(4), 444–457. https://doi.org/10.1038/s42255-022-00551-7

Wang, X., Zeldin, S., Shi, H., Zhu, C., Saito, Y., Corey, K. E., Osganian, S. A., Remotti, H. E., Verna, E. C., Pajvani, U. B., Schwabe, R. F., & Tabas, I. (2022). TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis. Journal of Hepatology, 76(4), 910–920. https://doi.org/10.1016/j.jhep.2021.11.031

Tall, A. R., & Wang, N. (2022). New insights into cholesterol efflux via ABCA1. Nature Cardiovascular Research, 1(3), 198–199. https://doi.org/10.1038/s44161-022-00036-6

Hsieh, J., Molusky, M. M., McCabe, K. M., Fotakis, P., Xiao, T., Tascau, L., Zeana-Schliep, L., DaSilva-Jardine, P., & Tall, A. R. (2022). TTC39B destabilizes retinoblastoma protein promoting hepatic lipogenesis in a sex-specific fashion. Journal of Hepatology, 76(2), 383–393. https://doi.org/10.1016/j.jhep.2021.09.021

Tian, Y., Fopiano, K. A., Buncha, V., Lang, L., Rudic, R. D., Filosa, J. A., Dou, H., & Bagi, Z. (2021). Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17. GeroScience, 44(1), 349–369. https://doi.org/10.1007/s11357-021-00476-1

Zanoni, P., Panteloglou, G., Othman, A., Haas, J. T., Meier, R., Rimbert, A., Futema, M., Abou Khalil, Y., Norrelykke, S. F., Rzepiela, A. J., Stoma, S., Stebler, M., van Dijk, F., Wijers, M., Wolters, J. C., Dalila, N., Huijkman, N. C. A., Smit, M., Gallo, A., … von Eckardstein, A. (2022). Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome. Circulation Research, 130(1), 80–95. https://doi.org/10.1161/circresaha.120.318141

Tall, A. R., Thomas, D. G., Gonzalez-Cabodevilla, A. G., & Goldberg, I. J. (2022). Addressing dyslipidemic risk beyond LDL-cholesterol. Journal of Clinical Investigation, 132(1). https://doi.org/10.1172/jci148559

Wang, L., Yu, J., Zhou, Q., Wang, X., Mukhanova, M., Du, W., Sun, L., Pajvani, U. B., & Accili, D. (2022). TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver. Cell Metabolism, 34(1), 158-170.e5. https://doi.org/10.1016/j.cmet.2021.11.013