Cholesterol trafficking to the ER leads to the activation of CaMKII/JNK/NLRP3 and promotes atherosclerosis

Yalcinkaya, M., Liu, W., Xiao, T., Abramowicz, S., Wang, R., Wang, N., Westerterp, M., & Tall, A. R. (2024). Cholesterol trafficking to the ER leads to the activation of CaMKII/JNK/NLRP3 and promotes atherosclerosis. Journal of Lipid Research, 65(4), 100534. https://doi.org/10.1016/j.jlr.2024.100534
Authors:
Mustafa Yalcinkaya
Wenli Liu
Tong Xiao
Sandra Abramowicz
Ranran Wang
Nan Wang
Marit Westerterp
Alan R Tall
Affiliated Authors:
Mustafa Yalcinkaya
Wenli Liu
Tong Xiao
Sandra Abramowicz
Ranran Wang
Nan Wang
Marit Westerterp
Alan R Tall
Columbia Affiliation:
Subjects:
Molecular Mechanisms of Inflammasome Activation and Regulation (OpenAlex Topic)
Cholesterol Metabolism and Atherosclerosis (OpenAlex Topic)
Immunological Mechanisms in Atherosclerosis Development (OpenAlex Topic)
NLR Family, Pyrin Domain-Containing 3 Protein (MeSH)
Atherosclerosis (MeSH)
Cholesterol (MeSH)
Calcium-Calmodulin-Dependent Protein Kinase Type 2 (MeSH)
Endoplasmic Reticulum (MeSH)
Author Keywords:
cholesterol
nlrp3 inflammasome
er
camkii
jnk
elink
Publication Type:
Article
Unique ID:
10.1016/j.jlr.2024.100534
PMID:
38522750
DOI:
10.1016/j.jlr.2024.100534
Journal:
Journal of Lipid Research
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: