Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers

Wang, X., Moore, M. P., Shi, H., Miyata, Y., Donnelly, S. K., Radiloff, D. R., & Tabas, I. (2023). Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers. Molecular Therapy - Methods & Clinical Development, 31, 101165. https://doi.org/10.1016/j.omtm.2023.101165
Authors:
Xiaobo Wang
Mary P. Moore
Hongxue Shi
Yoshinari Miyata
Sara K. Donnelly
Daniel R. Radiloff
Ira Tabas
Affiliated Authors:
Xiaobo Wang
Mary P. Moore
Hongxue Shi
Ira Tabas
Author Keywords:
galnac-sirna
hepatocyte-humanized mice
ihh
liver fibrosis
mash
nash/mash therapy, nash, taz, indian hedgehog
wwtr1
Publication Type:
Article
Unique ID:
10.1016/j.omtm.2023.101165
PMID:
Publication Date:
Data Source:
OpenAlex

Record Created: