BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis

Yalcinkaya, M., Liu, W., Thomas, L.-A., Olszewska, M., Xiao, T., Abramowicz, S., Papapetrou, E. P., Westerterp, M., Wang, N., Tabas, I., & Tall, A. R. (2023). BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis. Circulation, 148(22), 1764–1777. https://doi.org/10.1161/circulationaha.123.065344
Authors:
Mustafa Yalcınkaya
Wenli Liu
Leigh-anne Thomas
Malgorzata Olszewska
Tong Xiao
Sandra Abramowicz
Eirini P. Papapetrou
Marit Westerterp
Nan Wang
Ira Tabas
Alan R. Tall
Affiliated Authors:
Mustafa Yalcınkaya
Wenli Liu
Tong Xiao
Sandra Abramowicz
Marit Westerterp
Nan Wang
Ira Tabas
Alan R. Tall
Columbia Affiliation:
Subjects:
Atherosclerosis (MeSH)
Cardiovascular Diseases (MeSH)
Dioxygenases (MeSH)
Hypercholesterolemia (MeSH)
Molecular Mechanisms of Inflammasome Activation and Regulation (OpenAlex Topic)
Molecular Pathogenesis of Myeloproliferative Disorders (OpenAlex Topic)
Role of Pentraxins in Innate Immunity and Inflammation (OpenAlex Topic)
Author Keywords:
atherosclerosis
clonal hematopoiesis
extracellular traps
hypercholesterolemia
inflammasomes
neutrophils
phosphorylation
elink
Publication Type:
Article
Unique ID:
10.1161/circulationaha.123.065344
PMID:
37781816
DOI:
10.1161/circulationaha.123.065344
Journal:
Circulation
Publication Date:
Data Source:
OpenAlex
Source Link:
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