Geranylgeranyl Isoprenoids and Hepatic Rap1a Regulate Basal and Statin-Induced Expression of PCSK9

Wang, Y., Tinsley, B., Spolitu, S., Zadroga, J. A., Agarwal, H., Sarecha, A. K., & Ozcan, L. (2024). Geranylgeranyl isoprenoids and hepatic Rap1a regulate basal and statin-induced expression of PCSK9. Journal of Lipid Research, 65(3), 100515. https://doi.org/10.1016/j.jlr.2024.100515
Authors:
Yating Wang
Brea Tinsley
Stefano Spolitu
John A. Zadroga
Santosh R. Sukka
Amesh K. Sarecha
Lale Özcan
Affiliated Authors:
Yating Wang
Brea Tinsley
Stefano Spolitu
John A. Zadroga
Santosh R. Sukka
Amesh K. Sarecha
Lale Özcan
Columbia Affiliation:
Subjects:
Proprotein Convertase 9 (MeSH)
Hydroxymethylglutaryl-CoA Reductase Inhibitors (MeSH)
Cholesterol-lowering Treatment (OpenAlex Topic)
Computational Methods in Drug Discovery (OpenAlex Topic)
Nurr1/CoREST Pathway in Neuroprotection and Inflammation (OpenAlex Topic)
Author Keywords:
pcsk9
ldl
rap1a
statins
geranylgeranylation
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Publication Type:
Article
Unique ID:
10.1016/j.jlr.2024.100515
PMID:
38309417
DOI:
10.1016/j.jlr.2024.100515
Journal:
Journal of Lipid Research
Publication Date:
Data Source:
OpenAlex
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