Department of Pathology and Cell Biology

Displaying 601 - 650 of 1563CSV
Wang, X., Moore, M. P., Shi, H., Miyata, Y., Donnelly, S. K., Radiloff, D. R., & Tabas, I. (2023). Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers. Molecular Therapy - Methods & Clinical Development, 31, 101165. https://doi.org/10.1016/j.omtm.2023.101165
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Greer, S. U., Botello, J., Hongo, D., Levy, B., Shah, P., Rabinowitz, M., Miller, D. E., Im, K., & Kumar, A. (2023). Implementation of Nanopore sequencing as a pragmatic workflow for copy number variant confirmation in the clinic. Journal of Translational Medicine, 21(1). https://doi.org/10.1186/s12967-023-04243-y
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Nashman, Z., Runyan, A., Sydney, E., & Myeku, N. (2023). Modulation of the Immunoproteasome Affects Pathological Tau Aggregation in Alzheimer’s Disease. Alzheimer’s & Dementia, 19(S13). Portico. https://doi.org/10.1002/alz.071413
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Yao, Y., Green, I. K., Taub, A. B., Tazebay, R., LeSauter, J., & Silver, R. (2023). Vasculature of the Suprachiasmatic Nucleus: Pathways for Diffusible Output Signals. Journal of Biological Rhythms, 38(6), 571–585. https://doi.org/10.1177/07487304231189537
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Chang, Y.-H., Kang, E. Y.-C., Liu, L., Jenny, L. A., Khang, R., Seo, G. H., Lee, H., Chen, K.-J., Wu, W.-C., Hsiao, M.-C., & Wang, N.-K. (2023). Maternal mosaicism in SSBP1 causing optic atrophy with retinal degeneration: implications for genetic counseling. Orphanet Journal of Rare Diseases, 18(1). https://doi.org/10.1186/s13023-023-02748-9
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Chen, X., Li, Y., Zhu, F., Xu, X., Estrella, B., Pazos, M. A., McGuire, J. T., Karagiannis, D., Sahu, V., Mustafokulov, M., Scuoppo, C., Sánchez-Rivera, F. J., Soto-Feliciano, Y. M., Pasqualucci, L., Ciccia, A., Amengual, J. E., & Lu, C. (2023). Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39990-5
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Pitayu-Nugroho, L., Aubry, M., Laband, K., Geoffroy, H., Ganeswaran, T., Primadhanty, A., Canman, J. C., & Dumont, J. (2023). Kinetochore component function in C. elegans oocytes revealed by 4D tracking of holocentric chromosomes. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39702-z
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Giloteaux, L., Li, J., Hornig, M., Lipkin, W. I., Ruppert, D., & Hanson, M. R. (2023). Proteomics and cytokine analyses distinguish myalgic encephalomyelitis/chronic fatigue syndrome cases from controls. Journal of Translational Medicine, 21(1). https://doi.org/10.1186/s12967-023-04179-3
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Dmello, C., Zhao, J., Chen, L., Gould, A., Castro, B., Arrieta, V. A., Zhang, D. Y., Kim, K.-S., Kanojia, D., Zhang, P., Miska, J., Yeeravalli, R., Habashy, K., Saganty, R., Kang, S. J., Fares, J., Liu, C., Dunn, G., Bartom, E., … Sonabend, A. M. (2023). Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-36878-2
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Gupta, Y., Friedman, D. J., McNulty, M. T., Khan, A., Lane, B., Wang, C., Ke, J., Jin, G., Wooden, B., Knob, A. L., Lim, T. Y., Appel, G. B., Huggins, K., Liu, L., Mitrotti, A., Stangl, M. C., Bomback, A., Westland, R., Bodria, M., … Sanna-Cherchi, S. (2023). Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-43020-9
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Nuzzo, T., Russo, R., Errico, F., D’Amico, A., Tewelde, A. G., Valletta, M., Hassan, A., Tosi, M., Panicucci, C., Bruno, C., Bertini, E., Chambery, A., Pellizzoni, L., & Usiello, A. (2023). Nusinersen mitigates neuroinflammation in severe spinal muscular atrophy patients. Communications Medicine, 3(1). https://doi.org/10.1038/s43856-023-00256-2
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Park, J., Hall, C., Hubbard, B., LaMoia, T., Gaspar, R., Nasiri, A., Li, F., Zhang, H., Kim, J., Haeusler, R. A., Accili, D., Shulman, G. I., Yu, H., & Choi, E. (2023). MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis. Diabetes, 72(12), 1781–1794. https://doi.org/10.2337/db23-0314
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Gomes, P. A., Bodo, C., Nogueras-Ortiz, C., Samiotaki, M., Chen, M., Soares-Cunha, C., Silva, J. M., Coimbra, B., Stamatakis, G., Santos, L., Panayotou, G., Tzouanou, F., Waites, C. L., Gatsogiannis, C., Sousa, N., Kapogiannis, D., Costa-Silva, B., & Sotiropoulos, I. (2023). A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology. Cell Communication and Signaling, 21(1). https://doi.org/10.1186/s12964-023-01045-z
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Rehm, H. L., Alaimo, J. T., Aradhya, S., Bayrak-Toydemir, P., Best, H., Brandon, R., Buchan, J. G., Chao, E. C., Chen, E., Clifford, J., Cohen, A. S. A., Conlin, L. K., Das, S., Davis, K. W., del Gaudio, D., Del Viso, F., DiVincenzo, C., Eisenberg, M., Guidugli, L., … Rehm, H. (2023). The landscape of reported VUS in multi-gene panel and genomic testing: Time for a change. Genetics in Medicine, 25(12), 100947. https://doi.org/10.1016/j.gim.2023.100947
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Martuscello, R. T., Sivaprakasam, K., Hartstone, W., Kuo, S.-H., Konopka, G., Louis, E. D., & Faust, P. L. (2022). Gene Expression Analysis of Laser-Captured Purkinje Cells in the Essential Tremor Cerebellum. The Cerebellum, 22(6), 1166–1181. https://doi.org/10.1007/s12311-022-01483-4
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Mellgard, G., Stoffel, E., Michel, A., Iqbal, F., Provenzano, A., Akpan, I. J., Amengual, J., & Pro, B. (2023). Hypereosinophilic syndrome with leptomeningeal involvement: a not-so-classical case report of classical Hodgkin Lymphoma. Leukemia & Lymphoma, 64(13), 2208–2213. https://doi.org/10.1080/10428194.2023.2252124
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Irmady, K., Hale, C. R., Qadri, R., Fak, J., Simelane, S., Carroll, T., Przedborski, S., & Darnell, R. B. (2023). Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson’s disease. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39652-6
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Jentzsch, M. C., Tsang, S. H., & Koch, S. F. (2023). A New Preclinical Model of Retinitis Pigmentosa Due to Pde6g Deficiency. Ophthalmology Science, 3(4), 100332. https://doi.org/10.1016/j.xops.2023.100332
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Brockmann, L., Tran, A., Huang, Y., Edwards, M., Ronda, C., Wang, H. H., & Ivanov, I. I. (2023). Intestinal microbiota-specific Th17 cells possess regulatory properties and suppress effector T cells via c-MAF and IL-10. Immunity, 56(12), 2719-2735.e7. https://doi.org/10.1016/j.immuni.2023.11.003
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Holodniy, M., Pei, Y., Stack, G., Wade, C. L., Agrawal, Y., Barasch, N., Baddoura, F., Carmen Frias-Kletecka, M., Stacey Klutts, J., & Wang-rodriguez, J. (2023). 2353. SARS-CoV-2 Variants among US Veterans after COVID-19 Bivalent Vaccine Administration. Open Forum Infectious Diseases, 10(Supplement_2). https://doi.org/10.1093/ofid/ofad500.1974
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Tejwani, L., Ravindra, N. G., Lee, C., Cheng, Y., Nguyen, B., Luttik, K., Ni, L., Zhang, S., Morrison, L. M., Gionco, J., Xiang, Y., Yoon, J., Ro, H., Haidery, F., Grijalva, R. M., Bae, E., Kim, K., Martuscello, R. T., Orr, H. T., … Lim, J. (2024). Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1. Neuron, 112(3), 362-383.e15. https://doi.org/10.1016/j.neuron.2023.10.039
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Kassotis, A. S., Garcia, M. D. L., Sun, Y., Mbekeani, J. N., & Kazim, M. (2023). Clinically Aggressive Low-Grade Optic Nerve Glioma in an Adult Treated With Selumetinib. Journal of Neuro-Ophthalmology. https://doi.org/10.1097/wno.0000000000002023
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Soderquist, C. R., Freeman, C., Lin, W.-H., Leeman-Neill, R. J., Gu, Y., Carter, M. C., Stutzel, K. C., Sigcha, E., Alobeid, B., Fernandes, H., Bhagat, G., Mansukhani, M. M., & Hsiao, S. J. (2024). Clinical Utility and Reimbursement of Next-Generation Sequencing–Based Testing for Myeloid Malignancies. The Journal of Molecular Diagnostics, 26(1), 5–16. https://doi.org/10.1016/j.jmoldx.2023.09.012
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Ahimaz, P., Ross, M., Foltz, J., Sebastin, M., Naik, K., Kramer, T., Bogyo, K., & Primiano, M. (2023). Future Frontiers: Exploration of practices, challenges, and educational needs of genetic counselors in emerging subspecialties. Journal of Genetic Counseling, 32(6), 1238–1248. Portico. https://doi.org/10.1002/jgc4.1812
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Goldman, J. S., Uhlmann, W. R., Naini, A. B., Klitzman, R. L., & Marder, K. S. (2023). Genetic Testing of HTT Modifiers for Huntington’s Disease: Considerations for Clinical Guidelines. Movement Disorders, 38(12), 2151–2154. Portico. https://doi.org/10.1002/mds.29650
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Keller, M. B., Tian, X., Jang, M. K., Meda, R., Charya, A., Ozisik, D., Berry, G. J., Marboe, C. C., Kong, H., Ponor, I. L., Aryal, S., Orens, J. B., Shah, P. D., Nathan, S. D., & Agbor-Enoh, S. (2024). Organizing pneumonia is associated with molecular allograft injury and the development of antibody-mediated rejection. The Journal of Heart and Lung Transplantation, 43(4), 563–570. https://doi.org/10.1016/j.healun.2023.11.008
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Liang, L. W., Ladanyi, A., Kennel, P. J., Axsom, K. M., Sayer, G. T., Takeda, K., Sekulic, M., Uriel, N., Drakos, S., Colombo, P. C., & Yuzefpolskaya, M. (2023). Myocardial Recovery With HeartMate 3 Left Ventricular Assist Device: An Attainable Goal That Needs Better Precision. ASAIO Journal, 70(4), e65–e68. https://doi.org/10.1097/mat.0000000000002099
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Ao, S., Huang, G., Tang, X., Zhu, Z., Han, J., Wang, F., & Zhai, W. (2023). Anti‐immunoglobulin E provides an additional therapy to conventional steroids for Kimura’s disease. The Journal of Dermatology, 51(4), 602–606. Portico. https://doi.org/10.1111/1346-8138.17021
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Mann, J., Reznik, E., Santer, M., Fongheiser, M. A., Smith, N., Hirschhorn, T., Zandkarimi, F., Soni, R. K., Dafré, A. L., Miranda-Vizuete, A., Farina, M., & Stockwell, B. R. (2024). Ferroptosis inhibition by oleic acid mitigates iron-overload-induced injury. Cell Chemical Biology, 31(2), 249-264.e7. https://doi.org/10.1016/j.chembiol.2023.10.012
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Herb, B. R., Glover, H. J., Bhaduri, A., Colantuoni, C., Bale, T. L., Siletti, K., Hodge, R., Lein, E., Kriegstein, A. R., Doege, C. A., & Ament, S. A. (2023). Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus. Science Advances, 9(45). https://doi.org/10.1126/sciadv.adf6251
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Sha, Q., Fu, Z., Escobar Galvis, M. L., Madaj, Z., Underwood, M. D., Steiner, J. A., Dwork, A., Simpson, N., Galfalvy, H., Rozoklija, G., Achtyes, E. D., Mann, J. J., & Brundin, L. (2023). Integrative transcriptome- and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls. Molecular Psychiatry, 29(1), 134–145. https://doi.org/10.1038/s41380-023-02311-9
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Zhou, Q., & Greene, L. A. (2023). Dpep Inhibits Cancer Cell Growth and Survival via Shared and Context-Dependent Transcriptome Perturbations. Cancers, 15(22), 5318. https://doi.org/10.3390/cancers15225318
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Postler, T. S., Wang, A., Brundu, F. G., Wang, P., Wu, Z., Butler, K. E., Grinberg-Bleyer, Y., Krishnareddy, S., Lagana, S. M., Saqi, A., Oeckinghaus, A., Rabadan, R., & Ghosh, S. (2023). A pan-cancer analysis implicates human NKIRAS1 as a tumor-suppressor gene. Proceedings of the National Academy of Sciences, 120(46). https://doi.org/10.1073/pnas.2312595120
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Roufosse, C., Naesens, M., Haas, M., Lefaucheur, C., Mannon, R. B., Afrouzian, M., Alachkar, N., Aubert, O., Bagnasco, S. M., Batal, I., Bellamy, C. O. C., Broecker, V., Budde, K., Clahsen-Van Groningen, M., Coley, S. M., Cornell, L. D., Dadhania, D., Demetris, A. J., Einecke, G., … Mengel, M. (2024). The Banff 2022 Kidney Meeting Work Plan: Data-driven refinement of the Banff Classification for renal allografts. American Journal of Transplantation, 24(3), 350–361. https://doi.org/10.1016/j.ajt.2023.10.031
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Desai, N., Kudose, S., Remotti, H. E., Del Portillo, A., Fazlollahi, L., Lee, M. J., Xiong, Y., Moreira, R. K., Salomao, M., Fiel, M. I., Gonzalez, R. S., Misdraji, J., Gill, R. M., Hart, J., Kleiner, D. E., Drebber, U., Bellizzi, A. M., & Lagana, S. M. (2023). Erythrophagocytosis is not a reproducible finding in liver biopsies, and is not associated with clinical diagnosis of hemophagocytic lymphohistiocytosis. Virchows Archiv, 484(1), 61–69. https://doi.org/10.1007/s00428-023-03683-7
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Derakhshan, F., Da Cruz Paula, A., Selenica, P., da Silva, E. M., Grabenstetter, A., Jalali, S., Gazzo, A. M., Dopeso, H., Marra, A., Brown, D. N., Ross, D. S., Mandelker, D., Razavi, P., Chandarlapaty, S., Wen, H. Y., Brogi, E., Zhang, H., Weigelt, B., Pareja, F., & Reis-Filho, J. S. (2024). Nonlobular Invasive Breast Carcinomas with Biallelic Pathogenic CDH1 Somatic Alterations: A Histologic, Immunophenotypic, and Genomic Characterization. Modern Pathology, 37(2), 100375. https://doi.org/10.1016/j.modpat.2023.100375
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Xu, J. J., Chen, Y., Pantazi, J., Fernando, S., Alija, B., Sudunagunta, V., Bhagat, G., & Viny, A. D. (2023). Synergy of Stag2-Cohesin Loss Results in Expansion of Npm1c-Mutant Hematopoietic Stem and Progenitor Cells. Blood, 142(Supplement 1), 954–954. https://doi.org/10.1182/blood-2023-190627
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Khatiwada, P., Soni, M., & Muranski, P. (2023). Highly Active Cytotoxic CD4 + T Cells Targeting EBV Oncoproteins with Enhanced In Vivo Anti-Tumor and Self-Renewal Properties. Blood, 142(Supplement 1), 3464–3464. https://doi.org/10.1182/blood-2023-190690
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Lin, W.-H. W., Rodriguez Cortes, J., Aitken, M., Reglero, C., Laurent, A., Cooke, A., Belver, L., Bhagat, G., Rabadan, R., Ferrando, A. A., & Palomero, T. (2023). Role of the S1P Signaling Pathway in the Pathogenesis of Angioimmunoblastic T-Cell Lymphoma. Blood, 142(Supplement 1), 526–526. https://doi.org/10.1182/blood-2023-174090
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McBride, R. B., Suarez-Farinas, M., Ko, H. M., Chen, X., Liu, Q., & Harpaz, N. (2023). Density of Biopsy Sampling Required to Ensure Accurate Histological Assessment of Inflammation in Active Ulcerative Colitis. Inflammatory Bowel Diseases, 29(11), 1706–1712. https://doi.org/10.1093/ibd/izad063
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Cherng, H.-J. J., Yang, X., Yancey, R., Gordillo, C. A., Piorczynski, T. B., Chan, H. T., Ofori, K. N., Bhagat, G., Califano, A., Pro, B., Booher, K., Amengual, J. E., Reshef, R., & Sina, A. A. I. (2023). Methylated Whole Genome Cell-Free DNA Sequencing before Chimeric Antigen Receptor T-Cell Therapy for Large B-Cell Lymphoma Predicts Treatment Outcomes. Blood, 142(Supplement 1), 4371–4371. https://doi.org/10.1182/blood-2023-178376
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Orlando, E. H., Gould, P., Cuzzo, B., Ford, M., Chen, Y., Sanjurjo, A., May, B., Tsapepas, D., Leeman-Neill, R. J., Bhagat, G., Dube, G., Morris, H., Arcasoy, S., Latif, F., Martinez, M., Pereira, M., Lipsky, A. H., Sawas, A., Reshef, R., … Amengual, J. E. (2023). The Effect of Preemptive Rituximab Treatment in Patients with EBV Viremia after Solid Organ Transplantation on the Development of Post-Transplant Lymphoproliferative Disorder. Blood, 142(Supplement 1), 990–990. https://doi.org/10.1182/blood-2023-177823
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De Simone, P., Bal, E., Holmes, A., Hilton, L., Basso, K., Soni, R. K., Morin, R., Dalla-Favera, R., & Pasqualucci, L. (2023). BTG2 Super-Enhancer Mutations Disrupt TFAP4 Binding and Deregulate BTG2 Expression in Diffuse Large B-Cell Lymphoma. Blood, 142(Supplement 1), 523–523. https://doi.org/10.1182/blood-2023-190230
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Xu, J. J., Chen, Y., Pantazi, J., Fernando, S., Alija, B., Sudunagunta, V., Bhagat, G., Bowman, R. L., & Viny, A. D. (2023). Stag2-Cohesin Loss Attenuates Flt3 ITD Myeloid Blast Expansion Yet Preserves Mutant HSC. Blood, 142(Supplement 1), 2756–2756. https://doi.org/10.1182/blood-2023-190702
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Roh, D., Davis, J. M., Lee, T., Mitchell, P. M., Bookwalter, D., Stone, E., Karafin, M. S., Cushing, M. M., Spencer, B. R., Bruhn, R., Gottschall, J. L., Mast, A. E., Cable, R. G., Kleinman, S., & Hod, E. A. (2023). Assessing Donor and Platelet Transfusion Characteristics on Intracranial Hemorrhage Outcomes. Blood, 142(Supplement 1), 4038–4038. https://doi.org/10.1182/blood-2023-180236
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