R01DK128154

NIH – National Institute of Diabetes and Digestive and Kidney Diseases

Mulberry leaf extract combined with tryptophan improves sleep and post wake mood in adults with sleep complaints - A randomized cross-over study

Soon, C. S., Thota, R., Owen, L., Tian, L., Martin, F.-P., Mantantzis, K., Cherta-Murillo, A., Campos, V. C., Chkroun, C., Lavalle, L., Hartweg, M., St-Onge, M.-P., Chee, M. W. L., & Darimont, C. (2025). Mulberry leaf extract combined with tryptophan improves sleep and post wake mood in adults with sleep complaints – A randomized cross-over study. European Journal of Nutrition, 64(3). https://doi.org/10.1007/s00394-025-03643-8
Authors:
Chun Siong Soon
Rohith Thota
Lauren Owen
Liang Tian
Francois-Pierre Martin
Konstantinos Mantantzis
Anna Cherta-Murillo
Vanessa Caroline Campos
Célina Chkroun
Luca Lavalle
Mickaël Hartweg
Marie-Pierre St-Onge
Michael W L Chee
Christian Darimont
Affiliated Authors:
Marie-Pierre St-Onge
Subjects:
Author Keywords:
actigraphy
continuous glucose monitoring
mulberry leaf extract
nocturnal glycemia
sleep quality
tryptophan
glucose
magnesium
nicotinamide
protein hydrolysate
pyridoxine
zinc
blood glucose
plant extracts
mulberry extract
whey protein
plant extract
actimetry
adult
article
brief mood introspection scale
clinical article
cognition
controlled study
crossover procedure
double blind procedure
female
glycemic load
human
intention to treat analysis
karolinska sleepiness scale
male
maximum concentration
meal
mediation analysis
mental performance
mood
mood disorder assessment
mulberry
plant leaf
profile of mood states
randomized controlled trial
saliva level
self report
sleep disorder
sleep disorder assessment
sleep efficiency
sleep initiation
sleep latency
sleep parameters
urinalysis
affect
chemistry
dietary supplement
drug effect
glucose blood level
metabolism
middle aged
morus
physiology
postprandial state
sleep
cross-over studies
dietary supplements
double-blind method
humans
plant leaves
postprandial period
Grants:
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1007/s00394-025-03643-8
PMID:
Publication Date:
Data Source:
PubMed

Record Created:

Shortened sleep duration impairs adipose tissue adrenergic stimulation of lipolysis in postmenopausal women

Singh, P., Beyl, R. A., Stephens, J. M., Richard, A. J., Boudreau, A., Caitlin Hebert, R., Noland, R. C., Burk, D. H., Ghosh, S., Staszkiewicz, J., Michael Salbaum, J., Broussard, J. L., St‐Onge, M., Ravussin, E., & Marlatt, K. L. (2024). Shortened sleep duration impairs adipose tissue adrenergic stimulation of lipolysis in postmenopausal women. Obesity, 32(12), 2264–2274. Portico. https://doi.org/10.1002/oby.24162
Authors:
Prachi Singh
Robbie A Beyl
Jacqueline M Stephens
Allison J Richard
Anik Boudreau
R Caitlin Hebert
Robert C Noland
David H Burk
Sujoy Ghosh
Jaroslaw Staszkiewicz
J Michael Salbaum
Josiane L Broussard
Marie-Pierre St-Onge
Eric Ravussin
Kara L Marlatt
Affiliated Authors:
Marie-Pierre St-Onge
Subjects:
Grants:
R01HL166306 (NIH – National Heart, Lung, and Blood Institute)
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
R01DK125653 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
K01DK128227 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30DK072476 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P20GM103528 (NIH – National Institute of General Medical Sciences)
U54GM104940 (NIH – National Institute of General Medical Sciences)
P20GM135002 (NIH – National Institute of General Medical Sciences)
Publication Type:
Article
Unique ID:
10.1002/oby.24162
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created:

Response to Comment on Zuraikat et al. Chronic Insufficient Sleep in Women Impairs Insulin Sensitivity Independent of Adiposity Changes: Results of a Randomized Trial. Diabetes Care 2024;47:117–125

St-Onge, M.-P., Zuraikat, F. M., Laferrère, B., Jelic, S., & Aggarwal, B. (2024). Response to Comment on Zuraikat et al. Chronic Insufficient Sleep in Women Impairs Insulin Sensitivity Independent of Adiposity Changes: Results of a Randomized Trial. Diabetes Care 2024;47:117–125. Diabetes Care, 47(4), e37–e38. https://doi.org/10.2337/dci24-0013
Authors:
Marie‐Pierre St‐Onge
Faris M. Zuraikat
Blandine Laferrère
Sanja Jelić
Brooke Aggarwal
Affiliated Authors:
Marie‐Pierre St‐Onge
Faris M. Zuraikat
Blandine Laferrère
Sanja Jelić
Brooke Aggarwal
Grants:
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
R01HL137234 (NIH – National Heart, Lung, and Blood Institute)
R01HL128226 (NIH – National Heart, Lung, and Blood Institute)
R01HL106041 (NIH – National Heart, Lung, and Blood Institute)
P30DK063608 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01AG065569 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.2337/dci24-0013
PMID:
Journal:
Publication Date:
Data Source:
OpenAlex

Record Created:

The effects of sustained mild sleep restriction on stress and distress among healthy adults: Findings from two randomized crossover studies

Benasi, G., Cheng, B., Aggarwal, B., & St-Onge, M.-P. (2024). The effects of sustained mild sleep restriction on stress and distress among healthy adults: Findings from two randomized crossover studies. Sleep Medicine, 115, 83–87. https://doi.org/10.1016/j.sleep.2024.02.001
Authors:
Giada Benasi
Bin Cheng
Brooke Aggarwal
Marie-Pierre St-Onge
Affiliated Authors:
Giada Benasi
Bin Cheng
Brooke Aggarwal
Marie-Pierre St-Onge
Author Keywords:
sleep restriction
stress
anxiety
depression
rumination
cortisol
Grants:
UL1TR001873 (NIH – National Center for Advancing Translational Sciences)
R01HL142648 (NIH – National Heart, Lung, and Blood Institute)
R01HL128226 (NIH – National Heart, Lung, and Blood Institute)
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
T32DK007559 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1016/j.sleep.2024.02.001
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created:

Chronic Insufficient Sleep in Women Impairs Insulin Sensitivity Independent of Adiposity Changes: Results of a Randomized Trial

Zuraikat, F. M., Laferrère, B., Cheng, B., Scaccia, S. E., Cui, Z., Aggarwal, B., Jelic, S., & St-Onge, M.-P. (2023). Chronic Insufficient Sleep in Women Impairs Insulin Sensitivity Independent of Adiposity Changes: Results of a Randomized Trial. Diabetes Care, 47(1), 117–125. https://doi.org/10.2337/dc23-1156
Authors:
Faris M Zuraikat
Blandine Laferrère
Bin Cheng
Samantha E Scaccia
Zuoqiao Cui
Brooke Aggarwal
Sanja Jelic
Marie-Pierre St-Onge
Affiliated Authors:
Faris M Zuraikat
Blandine Laferrère
Bin Cheng
Samantha E Scaccia
Zuoqiao Cui
Brooke Aggarwal
Sanja Jelic
Marie-Pierre St-Onge
Grants:
UL1TR001873 (NIH – National Center for Advancing Translational Sciences)
T32HL007343 (NIH – National Heart, Lung, and Blood Institute)
R01HL106041 (NIH – National Heart, Lung, and Blood Institute)
R01HL137234 (NIH – National Heart, Lung, and Blood Institute)
R01HL128226 (NIH – National Heart, Lung, and Blood Institute)
R56HL106041 (NIH – National Heart, Lung, and Blood Institute)
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
P30DK063608 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30DK026687 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01AG065569 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.2337/dc23-1156
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created:

Paradoxical Effects of Prolonged Insufficient Sleep on Lipid Profile: A Pooled Analysis of 2 Randomized Trials

Barragán, R., Zuraikat, F. M., Cheng, B., Scaccia, S. E., Cochran, J., Aggarwal, B., Jelic, S., & St‐Onge, M. (2023). Paradoxical Effects of Prolonged Insufficient Sleep on Lipid Profile: A Pooled Analysis of 2 Randomized Trials. Journal of the American Heart Association, 12(20). https://doi.org/10.1161/jaha.123.032078
Authors:
Rocío Barragán
Faris M Zuraikat
Bin Cheng
Samantha E Scaccia
Justin Cochran
Brooke Aggarwal
Sanja Jelic
Marie-Pierre St-Onge
Affiliated Authors:
Rocío Barragán
Faris M Zuraikat
Bin Cheng
Samantha E Scaccia
Justin Cochran
Brooke Aggarwal
Sanja Jelic
Marie-Pierre St-Onge
Subjects:
Author Keywords:
clinical trial
inflammation
insufficient sleep
lipid profile
sleep
Grants:
UL1TR001873 (NIH – National Center for Advancing Translational Sciences)
R01HL137234 (NIH – National Heart, Lung, and Blood Institute)
R01HL106041 (NIH – National Heart, Lung, and Blood Institute)
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
T32HL007343 (NIH – National Heart, Lung, and Blood Institute)
R01HL128226 (NIH – National Heart, Lung, and Blood Institute)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1161/jaha.123.032078
PMID:
Publication Date:
Data Source:
PubMed

Record Created:

The interrelationship between sleep, diet, and glucose metabolism

St-Onge, M.-P., Cherta-Murillo, A., Darimont, C., Mantantzis, K., Martin, F. P., & Owen, L. (2023). The interrelationship between sleep, diet, and glucose metabolism. Sleep Medicine Reviews, 69, 101788. https://doi.org/10.1016/j.smrv.2023.101788
Authors:
Marie-Pierre St-Onge
Anna Cherta-Murillo
Christian Darimont
Konstantinos Mantantzis
François Pierre Martin
Lauren Owen
Affiliated Authors:
Marie-Pierre St-Onge
Subjects:
Author Keywords:
diet
energy balance
food intake
glucose
obesity
orexin
type 2 diabetes
Grants:
R01HL142648 (NIH – National Heart, Lung, and Blood Institute)
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1016/j.smrv.2023.101788
PMID:
Publication Date:
Data Source:
PubMed

Record Created:

Dimensions of sleep quality are related to objectively measured eating behaviors among children at high familial risk for obesity

Zuraikat, F. M., Bauman, J. M., Setzenfand, M. N., Arukwe, D. U., Rolls, B. J., & Keller, K. L. (2023). Dimensions of sleep quality are related to objectively measured eating behaviors among children at high familial risk for obesity. Obesity, 31(5), 1216–1226. Portico. https://doi.org/10.1002/oby.23754
Authors:
Faris M Zuraikat
Jonathan M Bauman
Marissa N Setzenfand
David U Arukwe
Barbara J Rolls
Kathleen L Keller
Affiliated Authors:
Faris M Zuraikat
Grants:
UL1TR002014 (NIH – National Center for Advancing Translational Sciences)
T32HL007343 (NIH – National Heart, Lung, and Blood Institute)
R01DK110060 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK126050 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1002/oby.23754
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created:

Effect of sleep restriction on insulin sensitivity and energy metabolism in postmenopausal women: A randomized crossover trial

Singh, P., Beyl, R. A., Stephens, J. M., Noland, R. C., Richard, A. J., Boudreau, A., Hebert, R. C., Ravussin, E., Broussard, J. L., St‐Onge, M., & Marlatt, K. L. (2023). Effect of sleep restriction on insulin sensitivity and energy metabolism in postmenopausal women: A randomized crossover trial. Obesity, 31(5), 1204–1215. Portico. https://doi.org/10.1002/oby.23739
Authors:
Prachi Singh
Robbie A Beyl
Jacqueline M Stephens
Robert C Noland
Allison J Richard
Anik Boudreau
R Caitlin Hebert
Eric Ravussin
Josiane L Broussard
Marie-Pierre St-Onge
Kara L Marlatt
Affiliated Authors:
Marie-Pierre St-Onge
Subjects:
Grants:
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
K01DK128227 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK125653 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30DK048520 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P30DK072476 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
U54GM104940 (NIH – National Institute of General Medical Sciences)
Publication Type:
Article
Unique ID:
10.1002/oby.23739
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created:

Exploring the Role of Dairy Products In Sleep Quality: From Population Studies to Mechanistic Evaluations

St-Onge, M.-P., Zuraikat, F. M., & Neilson, M. (2023). Exploring the Role of Dairy Products In Sleep Quality: From Population Studies to Mechanistic Evaluations. Advances in Nutrition, 14(2), 283–294. https://doi.org/10.1016/j.advnut.2023.01.004
Authors:
Marie-Pierre St-Onge
Faris M Zuraikat
Mackenzie Neilson
Affiliated Authors:
Marie-Pierre St-Onge
Faris M Zuraikat
Mackenzie Neilson
Subjects:
Author Keywords:
dairy intake
dairy proteins
fermented dairy
magnesium
sleep quality
zinc
Grants:
T32HL007343 (NIH – National Heart, Lung, and Blood Institute)
R35HL155670 (NIH – National Heart, Lung, and Blood Institute)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1016/j.advnut.2023.01.004
PMID:
Publication Date:
Data Source:
PubMed

Record Created:

Keeping an eye on circadian time in clinical research and medicine

Klerman, E. B., Brager, A., Carskadon, M. A., Depner, C. M., Foster, R., Goel, N., Harrington, M., Holloway, P. M., Knauert, M. P., LeBourgeois, M. K., Lipton, J., Merrow, M., Montagnese, S., Ning, M., Ray, D., Scheer, F. A. J. L., Shea, S. A., Skene, D. J., Spies, C., … Burgess, H. J. (2022). Keeping an eye on circadian time in clinical research and medicine. Clinical and Translational Medicine, 12(12). Portico. https://doi.org/10.1002/ctm2.1131
Authors:
Elizabeth B Klerman
Allison Brager
Mary A Carskadon
Christopher M Depner
Russell Foster
Namni Goel
Mary Harrington
Paul M Holloway
Melissa P Knauert
Monique K LeBourgeois
Jonathan Lipton
Martha Merrow
Sara Montagnese
Mingming Ning
David Ray
Frank A J L Scheer
Steven A Shea
Debra J Skene
Claudia Spies
Bart Staels
Marie-Pierre St-Onge
Steffen Tiedt
Phyllis C Zee
Helen J Burgess
Affiliated Authors:
Marie-Pierre St-Onge
Subjects:
Author Keywords:
chronobiology
chronomedicine
circadian
circadian medicine
daily
diurnal
human
time-of-day
translational
Grants:
R01HD103665 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
R01HD107064 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
R01HL153969 (NIH – National Heart, Lung, and Blood Institute)
R03HL157009 (NIH – National Heart, Lung, and Blood Institute)
R01HL141706 (NIH – National Heart, Lung, and Blood Institute)
R35HL155681 (NIH – National Heart, Lung, and Blood Institute)
R01HL151368 (NIH – National Heart, Lung, and Blood Institute)
K23HL138229 (NIH – National Heart, Lung, and Blood Institute)
R01HL140574 (NIH – National Heart, Lung, and Blood Institute)
R01HL142116 (NIH – National Heart, Lung, and Blood Institute)
K01HL145099 (NIH – National Heart, Lung, and Blood Institute)
R01HL140580 (NIH – National Heart, Lung, and Blood Institute)
R01HL142648 (NIH – National Heart, Lung, and Blood Institute)
R01DK127254 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK124280 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK102624 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK117488 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
P20GM139743 (NIH – National Institute of General Medical Sciences)
R01MH121531 (NIH – National Institute of Mental Health)
R21NS113065 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS067139 (NIH – National Institute of Neurological Disorders and Stroke)
U01NS114001 (NIH – National Institute of Neurological Disorders and Stroke)
UE5NS128293 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS093415 (NIH – National Institute of Neurological Disorders and Stroke)
RF1NS126547 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS114526 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS099055 (NIH – National Institute of Neurological Disorders and Stroke)
R01NR018891 (NIH – National Institute of Nursing Research)
RF1AG059867 (NIH – National Institute On Aging)
R01AG053838 (NIH – National Institute On Aging)
U54AG062322 (NIH – National Institute On Aging)
P01AG011412 (NIH – National Institute On Aging)
R01AA025593 (NIH – National Institute On Alcohol Abuse and Alcoholism)
R21DA052861 (NIH – National Institute On Drug Abuse)
Publication Type:
Article
Unique ID:
10.1002/ctm2.1131
PMID:
Publication Date:
Data Source:
PubMed

Record Created:

Sleep and Diet: Mounting Evidence of a Cyclical Relationship

Zuraikat, F. M., Wood, R. A., Barragán, R., & St-Onge, M.-P. (2021). Sleep and Diet: Mounting Evidence of a Cyclical Relationship. Annual Review of Nutrition, 41(1), 309–332. https://doi.org/10.1146/annurev-nutr-120420-021719
Authors:
Faris M Zuraikat
Rebecca A Wood
Rocío Barragán
Marie-Pierre St-Onge
Affiliated Authors:
Faris M Zuraikat
Rebecca A Wood
Rocío Barragán
Marie-Pierre St-Onge
Subjects:
Diet (MeSH)
Sleep (MeSH)
Author Keywords:
diet
insomnia
melatonin
nutrition
sleep
tryptophan
Grants:
T32HL007343 (NIH – National Heart, Lung, and Blood Institute)
R01HL128226 (NIH – National Heart, Lung, and Blood Institute)
R01HL142648 (NIH – National Heart, Lung, and Blood Institute)
R01DK128154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
Publication Type:
Article
Unique ID:
10.1146/annurev-nutr-120420-021719
PMID:
Publication Date:
Data Source:
PubMed

Record Created: