Molecular Mechanisms of Depression Treatment Strategies
Subject Vocabulary
OpenAlex Topic
Unique ID
https://openalex.org/T11071
Chen, B. K., Hunsberger, H. C., Whye, A., Matthews, L. C., Yook, A., Willner, M. J., Logan, R. W., Johns, S., Weisblum, E., & Denny, C. A. (2025). Combinatorial targeting of NMDARs and 5-HT4Rs exerts beneficial effects in a mouse model of Alzheimer’s disease. Alzheimer’s Research & Therapy, 17(1). https://doi.org/10.1186/s13195-025-01804-9
Subjects:
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Computational Methods in Drug Discovery
(OpenAlex Topic)
Alzheimer Disease
(MeSH)
Receptors, Serotonin, 5-HT4
(MeSH)
Benzofurans
(MeSH)
Publication Type:
Article
Unique ID:
10.1186/s13195-025-01804-9
PMID:
Journal:
Publication Date:
Data Source:
PubMed
Men, *Xiaoyu, Taylor, Z. L., Marshe, V. S., Blumberger, D. M., Karp, J. F., Kennedy, J. L., Lenze, E. J., Iii, C. F. R., Stefan, C., Mulsant, B. H., Ramsey, L. B., & Müller, D. J. (2025). UNDERSTANDING THE IMPACT OF CYP2D6-MEDIATED VENLAFAXINE PHARMACOKINETICS ON TREATMENT OUTCOMES IN LATE-LIFE DEPRESSION. International Journal of Neuropsychopharmacology, 28(Supplement_1), i329–i330. https://doi.org/10.1093/ijnp/pyae059.589
Columbia Affiliation:
Subjects:
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Effects of Ketogenic Diet on Health
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.1093/ijnp/pyae059.589
Publication Date:
Data Source:
OpenAlex
Source Link:
Record Created:
Kenowsky, S., Shao, Y., Heller, S., Golomb, J. B., Vedvyas, A., Dafflisio, G., Zhang, Q., Torossian, H., Sadowski, M. J., Wisniewski, T., Masurkar, A. V., & Reisberg, B. (2024). Nonpharmacologic Management of Behavioral and Psychological Symptoms of Dementia in Community‐Residing Persons with Moderately‐Severe Alzheimer’s Disease: One Year Results from a Randomized Controlled Trial. Alzheimer’s & Dementia, 20(S4). Portico. https://doi.org/10.1002/alz.090018
Subjects:
Cholinesterase Inhibitors in Neurodegenerative Diseases
(OpenAlex Topic)
Diagnosis and Management of Alzheimer's Disease
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.1002/alz.090018
DOI:
Journal:
Publication Date:
Data Source:
OpenAlex
Source Link:
Record Created:
Laroy, M., Bouckaert, F., Ousdal, O. T., Dols, A., Rhebergen, D., van Exel, E., van Wingen, G., van Waarde, J., Verdijk, J., Kessler, U., Bartsch, H., Jorgensen, M. B., Paulson, O. B., Nordanskog, P., Prudic, J., Sienaert, P., Vandenbulcke, M., Oltedal, L., & Emsell, L. (2024). Characterization of gray matter volume changes from one week to 6 months after termination of electroconvulsive therapy in depressed patients. Brain Stimulation, 17(4), 876–886. https://doi.org/10.1016/j.brs.2024.07.015
Subjects:
Electroconvulsive Therapy
(MeSH)
Gray Matter
(MeSH)
Magnetic Resonance Imaging
(MeSH)
Efficacy and Safety of Electroconvulsive Therapy
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Analysis of Brain Functional Connectivity Networks
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.1016/j.brs.2024.07.015
PMID:
Journal:
Publication Date:
Data Source:
OpenAlex
Record Created:
Immune-Targeted Therapies for Depression
Rizk, M. M., Bolton, L., Cathomas, F., He, H., Russo, S. J., Guttman-Yassky, E., Mann, J. J., & Murrough, J. (2024). Immune-Targeted Therapies for Depression. The Journal of Clinical Psychiatry, 85(3). https://doi.org/10.4088/jcp.23nr15243
Subjects:
Antibodies, Monoclonal
(MeSH)
Antidepressive Agents
(MeSH)
Neuroimmune Interaction in Psychiatric Disorders
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Effects of Stress on Brain Function and Health
(OpenAlex Topic)
Grants:
R01MH127820
(NIH – National Institute of Mental Health)
R01MH104559
(NIH – National Institute of Mental Health)
R01MH133299
(NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.4088/jcp.23nr15243
PMID:
Journal:
Publication Date:
Data Source:
OpenAlex
Record Created:
Sajid, S., Galfalvy, H. C., Keilp, J. G., Burke, A. K., Mann, J. J., & Grunebaum, M. F. (2024). Acute Dissociation and Ketamine’s Antidepressant and Anti-Suicidal Ideation Effects in a Midazolam-Controlled Trial. International Journal of Neuropsychopharmacology, 27(4). https://doi.org/10.1093/ijnp/pyae017
Subjects:
Ketamine
(MeSH)
Suicidal Ideation
(MeSH)
Midazolam
(MeSH)
Antidepressive Agents
(MeSH)
Dissociative Disorders
(MeSH)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Molecular Mechanisms of Neurodegenerative Diseases
(OpenAlex Topic)
Neuroimmune Interaction in Psychiatric Disorders
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.1093/ijnp/pyae017
PMID:
DOI:
Publication Date:
Data Source:
OpenAlex
Record Created:
Men, X., Taylor, Z. L., Marshe, V. S., Blumberger, D. M., Karp, J. F., Kennedy, J. L., Lenze, E. J., Reynolds, C. F., Stefan, C., Mulsant, B. H., Ramsey, L. B., & Müller, D. J. (2024). CYP2D6 Phenotype Influences Pharmacokinetic Parameters of Venlafaxine: Results from a Population Pharmacokinetic Model in Older Adults with Depression. Clinical Pharmacology & Therapeutics, 115(5), 1065–1074. Portico. https://doi.org/10.1002/cpt.3162
Columbia Affiliation:
Subjects:
Cyclohexanols
(MeSH)
Cytochrome P-450 CYP2D6
(MeSH)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Drug Metabolism and Pharmacogenomics
(OpenAlex Topic)
Network Analysis of Psychopathology and Mental Disorders
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.1002/cpt.3162
PMID:
DOI:
Publication Date:
Data Source:
OpenAlex
Record Created:
Clozapine Withdrawal Catatonia: A Case Report
Jagtiani, A., Nagi, T., Gandhi, R., & Rizvi, A. (2024). Clozapine Withdrawal Catatonia: A Case Report. Cureus. https://doi.org/10.7759/cureus.52462
Subjects:
Efficacy and Safety of Electroconvulsive Therapy
(OpenAlex Topic)
Epidemiology and Management of Bipolar Disorder
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.7759/cureus.52462
PMID:
DOI:
Journal:
Publication Date:
Data Source:
OpenAlex
Source Link:
Record Created:
Baune, B. T., Minelli, A., Carpiniello, B., Contu, M., Domínguez Barragán, J., Donlo, C., Ferensztajn-Rochowiak, E., Glaser, R., Kelch, B., Kobelska, P., Kolasa, G., Kopeć, D., Martínez de Lagrán Cabredo, M., Martini, P., Mayer, M.-A., Menesello, V., Paribello, P., Perera Bel, J., Perusi, G., … Dierssen, M. (2024). An integrated precision medicine approach in major depressive disorder: a study protocol to create a new algorithm for the prediction of treatment response. Frontiers in Psychiatry, 14. https://doi.org/10.3389/fpsyt.2023.1279688
Columbia Affiliation:
Subjects:
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Network Analysis of Psychopathology and Mental Disorders
(OpenAlex Topic)
Neuroimmune Interaction in Psychiatric Disorders
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.3389/fpsyt.2023.1279688
PMID:
Journal:
Publication Date:
Data Source:
OpenAlex
Record Created:
Sajid, S., Lawrence, R. E., Galfalvy, H. C., Keilp, J. G., Moitra, V. K., Mann, J. J., & Grunebaum, M. F. (2024). Intramuscular ketamine vs. midazolam for rapid risk-reduction in suicidal, depressed emergency patients: Clinical trial design and rationale. Journal of Affective Disorders Reports, 15, 100690. https://doi.org/10.1016/j.jadr.2023.100690
Subjects:
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Cognitive Mechanisms of Anxiety and Depression
(OpenAlex Topic)
Efficacy and Safety of Electroconvulsive Therapy
(OpenAlex Topic)
Grants:
R01MH125155
(NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.1016/j.jadr.2023.100690
PMID:
Publication Date:
Data Source:
OpenAlex
Source Link:
Record Created:
Mariani, J. J., Dobbins, R. L., Heath, A., Gray, F., & Hassman, H. (2023). Open‐label investigation of rapid initiation of extended‐release buprenorphine in patients using fentanyl and fentanyl analogs. The American Journal on Addictions, 33(1), 8–14. Portico. https://doi.org/10.1111/ajad.13484
Columbia Affiliation:
Subjects:
Opioid Epidemic in the United States
(OpenAlex Topic)
Challenges in Pain Management and Treatment
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Buprenorphine
(MeSH)
Opioid-Related Disorders
(MeSH)
Publication Type:
Article
Unique ID:
10.1111/ajad.13484
PMID:
DOI:
Journal:
Publication Date:
Data Source:
PubMed
Source Link:
Record Created:
Suarez-Jimenez, B., Lazarov, A., Zhu, X., Pine, D. S., Bar-Haim, Y., & Neria, Y. (2022). Attention allocation to negatively-valenced stimuli in PTSD is associated with reward-related neural pathways. Psychological Medicine, 53(10), 4666–4674. https://doi.org/10.1017/s003329172200157x
Columbia Affiliation:
Subjects:
Posttraumatic Stress Disorder and Human Resilience
(OpenAlex Topic)
Analysis of Brain Functional Connectivity Networks
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Grants:
R01MH131532
(NIH – National Institute of Mental Health)
T32MH020004
(NIH – National Institute of Mental Health)
ZIAMH002782
(NIH – National Institute of Mental Health)
R01MH105355
(NIH – National Institute of Mental Health)
K01MH118428
(NIH – National Institute of Mental Health)
ZIAMH002781
(NIH – National Institute of Mental Health)
K01MH122774
(NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.1017/s003329172200157x
PMID:
Journal:
Publication Date:
Data Source:
PubMed
Record Created:
A Virtual-First Telehealth Treatment Model for Opioid Use Disorder
Williams, A. R., Aronowitz, S., Gallagher, R., Behar, E., Gray, Z., & Bisaga, A. (2022). A Virtual-First Telehealth Treatment Model for Opioid Use Disorder. Journal of General Internal Medicine, 38(3), 814–816. https://doi.org/10.1007/s11606-022-07955-x
Subjects:
Opioid Epidemic in the United States
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Digital Mental Health Interventions and Efficacy
(OpenAlex Topic)
Opioid-Related Disorders
(MeSH)
Telemedicine
(MeSH)
Publication Type:
Article
Unique ID:
10.1007/s11606-022-07955-x
PMID:
Journal:
Publication Date:
Data Source:
PubMed
Source Link:
Record Created:
Bartlett, E. A., Yttredahl, A. A., Boldrini, M., Tyrer, A. E., Hill, K. R., Ananth, M. R., Milak, M. S., Oquendo, M. A., Mann, J. J., DeLorenzo, C., & Parsey, R. V. (2023). In vivo serotonin 1A receptor hippocampal binding potential in depression and reported childhood adversity. European Psychiatry, 66(1). https://doi.org/10.1192/j.eurpsy.2023.4
Subjects:
Receptor, Serotonin, 5-HT1A
(MeSH)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Neuroimmune Interaction in Psychiatric Disorders
(OpenAlex Topic)
Neural Mechanisms of Memory Formation and Spatial Navigation
(OpenAlex Topic)
Grants:
K01MH129780
(NIH – National Institute of Mental Health)
R01MH090276
(NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.1192/j.eurpsy.2023.4
PMID:
Journal:
Publication Date:
Data Source:
OpenAlex
Record Created:
Bloomfield-Clagett, B., Ballard, E. D., Greenstein, D. K., Wilkinson, S. T., Grunebaum, M. F., Murrough, J. W., Mathew, S. J., Phillips, J. L., Fava, M., Sanacora, G., & Zarate, C. A. (2022). A Participant-Level Integrative Data Analysis of Differential Placebo Response for Suicidal Ideation and Nonsuicidal Depressive Symptoms in Clinical Trials of Intravenous Racemic Ketamine. International Journal of Neuropsychopharmacology, 25(10), 827–838. https://doi.org/10.1093/ijnp/pyac055
Columbia Affiliation:
Subjects:
Ketamine
(MeSH)
Depressive Disorder, Major
(MeSH)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Neurobiological Mechanisms of Placebo and Nocebo Effects
(OpenAlex Topic)
Molecular Mechanisms of Neurodegenerative Diseases
(OpenAlex Topic)
Grants:
UL1TR001863
(NIH – National Center for Advancing Translational Sciences)
Publication Type:
Article
Unique ID:
10.1093/ijnp/pyac055
PMID:
DOI:
Publication Date:
Data Source:
Scopus
Source Link:
Record Created:
Mastrodonato, A., Pavlova, I., Kee, N. C., Pham, V. A., McGowan, J. C., Mann, J. J., & Denny, C. A. (2022). Prophylactic (R,S)-Ketamine Is Effective Against Stress-Induced Behaviors in Adolescent but Not Aged Mice. International Journal of Neuropsychopharmacology, 25(6), 512–523. https://doi.org/10.1093/ijnp/pyac020
Subjects:
Neuroimmune Interaction in Psychiatric Disorders
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Effects of Stress on Brain Function and Health
(OpenAlex Topic)
Ketamine
(MeSH)
Grants:
R01HD101402
(NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
R01MH108032
(NIH – National Institute of Mental Health)
F31MH122187
(NIH – National Institute of Mental Health)
R21NS114870
(NIH – National Institute of Neurological Disorders and Stroke)
F99NS124182
(NIH – National Institute of Neurological Disorders and Stroke)
R56AG058661
(NIH – National Institute On Aging)
R21AG064774
(NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1093/ijnp/pyac020
PMID:
DOI:
Publication Date:
Data Source:
Scopus
Record Created:
Mastrodonato, A., Pavlova, I., Kee, N., McGowan, J. C., Mann, J. J., & Denny, C. A. (2022). Acute (R,S)-Ketamine Administration Induces Sex-Specific Behavioral Effects in Adolescent but Not Aged Mice. Frontiers in Neuroscience, 16. https://doi.org/10.3389/fnins.2022.852010
Subjects:
Neuroimmune Interaction in Psychiatric Disorders
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Effects of Stress on Brain Function and Health
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.3389/fnins.2022.852010
PMID:
Journal:
Publication Date:
Data Source:
PubMed
Source Link:
Record Created:
Nestsiarovich, A., Reps, J. M., Matheny, M. E., DuVall, S. L., Lynch, K. E., Beaton, M., Jiang, X., Spotnitz, M., Pfohl, S. R., Shah, N. H., Torre, C. O., Reich, C. G., Lee, D. Y., Son, S. J., You, S. C., Park, R. W., Ryan, P. B., & Lambert, C. G. (2021). Predictors of diagnostic transition from major depressive disorder to bipolar disorder: a retrospective observational network study. Translational Psychiatry, 11(1). https://doi.org/10.1038/s41398-021-01760-6
Columbia Affiliation:
Subjects:
Epidemiology and Management of Bipolar Disorder
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Neuroimmune Interaction in Psychiatric Disorders
(OpenAlex Topic)
Bipolar Disorder
(MeSH)
Depressive Disorder, Major
(MeSH)
Psychotic Disorders
(MeSH)
Grants:
R56MH120826
(NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.1038/s41398-021-01760-6
PMID:
Journal:
Publication Date:
Data Source:
PubMed
Record Created:
Hill, K. R., Gardus, J. D., Bartlett, E. A., Perlman, G., Parsey, R. V., & DeLorenzo, C. (2021). Measuring brain glucose metabolism in order to predict response to antidepressant or placebo: A randomized clinical trial. NeuroImage: Clinical, 32, 102858. https://doi.org/10.1016/j.nicl.2021.102858
Columbia Affiliation:
Subjects:
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Positron Emission Tomography Imaging in Oncology
(OpenAlex Topic)
Analysis of Brain Functional Connectivity Networks
(OpenAlex Topic)
Depressive Disorder, Major
(MeSH)
Grants:
T32GM008444
(NIH – National Institute of General Medical Sciences)
R01MH104512
(NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.1016/j.nicl.2021.102858
PMID:
Journal:
Publication Date:
Data Source:
PubMed
Record Created:
Advancing psychotherapy in psychiatry: the contribution of the WPA Section on Psychotherapy
Alfonso, C. A., Tasman, A., Jimenez, A. L., & Della, C. D. (2021). Advancing psychotherapy in psychiatry: the contribution of the WPA Section on Psychotherapy. World Psychiatry, 20(3), 453–454. Portico. https://doi.org/10.1002/wps.20897
Columbia Affiliation:
Subjects:
Network Analysis of Psychopathology and Mental Disorders
(OpenAlex Topic)
Cognitive Mechanisms of Anxiety and Depression
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Publication Type:
Article
Unique ID:
10.1002/wps.20897
PMID:
DOI:
Journal:
Publication Date:
Data Source:
OpenAlex
Source Link:
Record Created:
How do we address treating the negative symptoms of schizophrenia pharmacologically?
Kantrowitz, J. T. (2021). How do we address treating the negative symptoms of schizophrenia pharmacologically? Expert Opinion on Pharmacotherapy, 22(14), 1811–1813. https://doi.org/10.1080/14656566.2021.1939677
Columbia Affiliation:
Subjects:
Schizophrenia Research and Treatment
(OpenAlex Topic)
Philosophical Perspectives on Health and Psychiatry
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Antipsychotic Agents
(MeSH)
Schizophrenia
(MeSH)
Publication Type:
Article
Unique ID:
10.1080/14656566.2021.1939677
PMID:
Journal:
Publication Date:
Data Source:
PubMed
Source Link:
Record Created:
Chen, B. K., Le Pen, G., Eckmier, A., Rubinstenn, G., Jay, T. M., & Denny, C. A. (2021). Fluoroethylnormemantine, A Novel Derivative of Memantine, Facilitates Extinction Learning Without Sensorimotor Deficits. International Journal of Neuropsychopharmacology, 24(6), 519–531. https://doi.org/10.1093/ijnp/pyab007
Subjects:
Neural Mechanisms of Memory Formation and Spatial Navigation
(OpenAlex Topic)
Molecular Mechanisms of Depression Treatment Strategies
(OpenAlex Topic)
Behavior, Animal
(MeSH)
Extinction, Psychological
(MeSH)
Fear
(MeSH)
Memantine
(MeSH)
Grants:
R01HD101402
(NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
F31MH121023
(NIH – National Institute of Mental Health)
R21NS114870
(NIH – National Institute of Neurological Disorders and Stroke)
R21AG064774
(NIH – National Institute On Aging)
R56AG058661
(NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1093/ijnp/pyab007
PMID:
DOI:
Publication Date:
Data Source:
Scopus