Effects of Ketogenic Diet on Health

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Ahuja, K., Pathania, S., Baron, N., Khlevner, J., Bialer, M., & Mait‐Kaufman, J. (2025). Chronic atrial and intestinal dysrhythmia: A rare genetic disorder of intestinal pseudo‐obstruction. JPGN Reports. Portico. https://doi.org/10.1002/jpr3.12158
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Mielke, M. M., Evans, J. K., Neiberg, R. H., Molina-Henry, D. P., Marcovina, S. M., Johnson, K. C., Carmichael, O. T., Rapp, S. R., Sachs, B. C., Ding, J., Shappell, H. M., Luchsinger, J. A., Espeland, M. A., & Hayden, K. M. (2025). Alzheimer Disease Blood Biomarkers and Cognition Among Individuals With Diabetes and Overweight or Obesity. JAMA Network Open, 8(2), e2458149. https://doi.org/10.1001/jamanetworkopen.2024.58149
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Men, *Xiaoyu, Taylor, Z. L., Marshe, V. S., Blumberger, D. M., Karp, J. F., Kennedy, J. L., Lenze, E. J., Iii, C. F. R., Stefan, C., Mulsant, B. H., Ramsey, L. B., & Müller, D. J. (2025). UNDERSTANDING THE IMPACT OF CYP2D6-MEDIATED VENLAFAXINE PHARMACOKINETICS ON TREATMENT OUTCOMES IN LATE-LIFE DEPRESSION. International Journal of Neuropsychopharmacology, 28(Supplement_1), i329–i330. https://doi.org/10.1093/ijnp/pyae059.589
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Matan-Lithwick, S., Misztal, M. C., Yang, M., DeLong, T., Tripathy, S., Dunn, J. T., Bennett, D. A., De Jager, P. L., Wang, Y., Fisher, D. W., Dong, H., & Felsky, D. (2025). A Transcriptomic Signature of Depressive Symptoms in Late Life. Biological Psychiatry Global Open Science, 5(3), 100448. https://doi.org/10.1016/j.bpsgos.2025.100448
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Lardieri, A., Thaker, V., Citron-Zafrin, K., Garvin, J. H., Zacharoulis, S., & Ladas, E. J. (2024). Pharmacologic Management of Obesity in Neuro-Oncology: A Case Report. Case Reports in Oncology, 18(1), 169–173. Portico. https://doi.org/10.1159/000543178
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Phillips, J., Dumitrescu, L. C., Archer, D. B., Regelson, A. N., Mukherjee, S., Lee, M. L., Choi, S., Scollard, P., Trittschuh, E. H., Kukull, W. A., Biber, S. A., Mez, J., Mahoney, E. R., Clifton, M., Libby, J. B., Walters, S., Bush, W. S., Engelman, C. D., … Lu, Q. (2024). Leveraging a Novel Phenotype to Identify Complex Traits and Biological Pathways Associated with Resilience to Alzheimer’s Disease. Alzheimer’s & Dementia, 20(S8). Portico. https://doi.org/10.1002/alz.095693
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Damuka, N., Miller, M., Krizan, I., Bhoopal, B., Orr, M. E., Gollepalli, K. K., Lockhart, S. N., Whitlow, C. T., Mintz, A., Craft, S., & Sai, K. K. S. (2024). PET Imaging of Microtubules in Cognitively Impaired and Normal Older Adults. Alzheimer’s & Dementia, 20(S8). Portico. https://doi.org/10.1002/alz.095392
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Okafor, A., Vartak, A., Johnson, A. S., Guzmán, D. S., Smith, A. C., Houlihan, H. M., Heuer, L. B., Rentería, M. A., Turney, I. C., Mayeux, R., Brickman, A. M., Manly, J. J., Gu, Y., & Lao, P. J. (2024). The Impact of Diet on AD Biomarkers in a Community‐Based Sample. Alzheimer’s & Dementia, 20(S9). Portico. https://doi.org/10.1002/alz.093624
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Gunasekaran, T. I., Lee, A. J., Lao, P. J., Gutierrez, J., Manly, J. J., Gu, Y., Brickman, A. M., Honig, L. S., Vardarajan, B. N., & Mayeux, R. (2024). Understanding Biomarker Discordance: MRI and PET Phenotypes Shed Light on Alzheimer’s Pathology. Alzheimer’s & Dementia, 20(S8). Portico. https://doi.org/10.1002/alz.095708
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Okafor, A., Vartak, A., Johnson, A. S., Guzmán, D. S., Smith, A. C., Houlihan, H. M., Heuer, L. B., Rentería, M. A., Turney, I. C., Mayeux, R., Brickman, A. M., Manly, J. J., Gu, Y., & Lao, P. J. (2024). The Impact of Diet on AD Biomarkers in a Community‐Based Sample. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.084728
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Sebastiani, P., Monti, S., Lustgarten, M. S., Song, Z., Ellis, D., Tian, Q., Schwaiger-Haber, M., Stancliffe, E., Leshchyk, A., Short, M. I., Ardisson Korat, A. V., Gurinovich, A., Karagiannis, T., Li, M., Lords, H. J., Xiang, Q., Marron, M. M., Bae, H., Feitosa, M. F., … Patti, G. J. (2024). Metabolite signatures of chronological age, aging, survival, and longevity. Cell Reports, 43(11), 114913. https://doi.org/10.1016/j.celrep.2024.114913
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Popp, C. J., Manoogian, E. N. C., & Laferrère, B. (2024). Meal Timing Interventions for Weight Loss and Metabolic Health—What Does the Evidence Tell Us So Far? JAMA Network Open, 7(11), e2442140. https://doi.org/10.1001/jamanetworkopen.2024.42140
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Gatto, N. M., Renz, A., Tom, S. E., Lyons, M., Macuiba, J. A., Dodd, T. S., Lind, B. K., Gray, S. L., Meyers, K., Larson, E. B., Nelson, J. C., McEvoy, L. K., Sankaran, S., Key, D., Litondo, J. A., & Crane, P. K. (2024). The Adult Changes in Thought (ACT) Medical Records Abstraction Project: A Resource for Research on Biological, Psychosocial and Behavioral Factors on the Aging Brain and Alzheimer’s Disease and Related Dementias. Brain Sciences, 14(11), 1075. https://doi.org/10.3390/brainsci14111075
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Díaz-Rizzolo, D. A., Santos Baez, L. S., Popp, C. J., Borhan, R., Sordi-Guth, A., Manoogian, E. N. C., Panda, S., Cheng, B., & Laferrère, B. (2024). Late eating is associated with poor glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 diabetes. Nutrition & Diabetes, 14(1). https://doi.org/10.1038/s41387-024-00347-6
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Ross, R. K., Inose, S., Shulman, M., Nunes, E. V., Zalla, L. C., Burlew, A. K., & Rudolph, K. E. (2024). Variation in Opioid Agonist Dosing in Clinical Trials by Race and Ethnicity. JAMA Network Open, 7(10), e2436612. https://doi.org/10.1001/jamanetworkopen.2024.36612
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Chevli, P. A., Schaich, C. L., Wood, A. C., TK, L. A., Mehta, A., Jain, V., Connelly, M., Craft, S., Shemesh, E., Luchsinger, J. A., Hayden, K. M., Sachs, B. C., Hughes, T. M., & Shapiro, M. D. (2024). Association of circulating ketone bodies with cognitive performance and dementia in the Multi‐Ethnic Study of Atherosclerosis (MESA). Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 16(4). Portico. https://doi.org/10.1002/dad2.70039
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Hamm, J. D., Laferrère, B., Albu, J. B., Kini, S., Pi-Sunyer, X., & Kissileff, H. R. (2024). Responsiveness and Reliability of a Sipping Device to Measure Motivation in Normal-Weight Individuals and Bariatric Surgery Patients. Nutrients, 16(17), 3001. https://doi.org/10.3390/nu16173001
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Damuka, N., Irmen, R. E., Krizan, I., Miller, M., Gollapelli, K. K., Bhoopal, B., Deep, O., Bansode, A., Lockhart, S. N., Orr, M. E., Jadiya, P., Bashetti, N., Kumar, J. V. S., Mintz, A., Whitlow, C. T., Craft, S., Macauley, S. L., & Solingapuram Sai, K. K. (2024). Exploring microtubule dynamics in Alzheimer’s disease: Longitudinal assessment using [11C]MPC‐6827 PET imaging in rodent models of Alzheimer’s‐related pathology. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14083
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Trumpff, C., Monzel, A. S., Sandi, C., Menon, V., Klein, H.-U., Fujita, M., Lee, A., Petyuk, V. A., Hurst, C., Duong, D. M., Seyfried, N. T., Wingo, A. P., Wingo, T. S., Wang, Y., Thambisetty, M., Ferrucci, L., Bennett, D. A., De Jager, P. L., & Picard, M. (2024). Psychosocial experiences are associated with human brain mitochondrial biology. Proceedings of the National Academy of Sciences, 121(27). https://doi.org/10.1073/pnas.2317673121
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Shishani, R., Wang, A., Lyo, V., Nandakumar, R., & Cummings, B. P. (2024). Vertical Sleeve Gastrectomy Reduces Gut Luminal Deoxycholic Acid Concentrations in Mice. Obesity Surgery, 34(7), 2483–2491. https://doi.org/10.1007/s11695-024-07288-0
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Ghooray, D. T., Xu, M., Shi, H., McClain, C. J., & Song, M. (2024). Hepatocyte-Specific Fads1 Overexpression Attenuates Western Diet-Induced Metabolic Phenotypes in a Rat Model. International Journal of Molecular Sciences, 25(9), 4836. https://doi.org/10.3390/ijms25094836
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Santos-Báez, L. S., Díaz-Rizzolo, D. A., Popp, C. J., Shaw, D., Fine, K. S., Altomare, A., St-Onge, M.-P., Manoogian, E. N. C., Panda, S., Cheng, B., & Laferrère, B. (2024). Diet and Meal Pattern Determinants of Glucose Levels and Variability in Adults with and without Prediabetes or Early-Onset Type 2 Diabetes: A Pilot Study. Nutrients, 16(9), 1295. https://doi.org/10.3390/nu16091295
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Cha, E., Choi, Y., Bancks, M., Faulkner, M. S., Dunbar, S. B., Umpierrez, G. E., Reis, J., Carnethon, M. R., Shikany, J. M., Yan, F., & Jacobs, D. R. (2024). Longitudinal changes in diet quality and food intake before and after diabetes awareness in American adults: the Coronary Artery Risk Development in Young Adults (CARDIA) study. BMJ Open Diabetes Research & Care, 12(2), e003800. https://doi.org/10.1136/bmjdrc-2023-003800
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Barbera, M., Lehtisalo, J., Perera, D., Aspö, M., Cross, M., De Jager Loots, C. A., Falaschetti, E., Friel, N., Luchsinger, J. A., Gavelin, H. M., Peltonen, M., Price, G., Neely, A. S., Thunborg, C., Tuomilehto, J., Mangialasche, F., Middleton, L., Ngandu, T., … Solomon, A. (2024). A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability: the MET-FINGER randomised controlled trial protocol. Alzheimer’s Research & Therapy, 16(1). https://doi.org/10.1186/s13195-023-01355-x
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Mullish, B. H., Michael, D. R., Dabcheva, M., Webberley, T. S., Coates, N., John, D. A., Wang, D., Luo, Y., Plummer, S. F., & Marchesi, J. R. (2024). A double‐blind, randomized, placebo‐controlled study assessing the impact of probiotic supplementation on the symptoms of irritable bowel syndrome in females. Neurogastroenterology & Motility, 36(4). Portico. https://doi.org/10.1111/nmo.14751
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Columbia Affiliation
Liu, B., Xie, D., Huang, X., Jin, S., Dai, Y., Sun, X., Li, D., Bennett, A. M., Diano, S., & Huang, Y. (2024). Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α. Diabetologia, 67(4), 724–737. https://doi.org/10.1007/s00125-023-06073-5
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Hoost, S. S., Honig, L. S., Kang, M. S., Sanchez, D., Reyes‐Dumeyer, D., Lantigua, R. A., Dage, J. L., Brickman, A. M., Manly, J. J., Mayeux, R., & Gu, Y. (2023). Nutrient intake in relation to longitudinal change of blood‐based biomarkers of Alzheimer’s disease. Alzheimer’s & Dementia, 19(S15). Portico. https://doi.org/10.1002/alz.079125
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Kalia, V., Reyes‐Dumeyer, D., Dubey, S., Nandakumar, R., Lee, A. J., Lantigua, R. A., Medrano, M., Mejia, D. R., Recio, P., Honig, L. S., Mayeux, R., Miller, G. W., & Vardarajan, B. N. (2023). Metabolites correlate with plasma biomarkers and clinical diagnosis of Alzheimer’s Disease. Alzheimer’s & Dementia, 19(S15). Portico. https://doi.org/10.1002/alz.078516
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Reddam, A., Bloomquist, T. R., Hu, H., Oberfield, S. E., Gallagher, D., Goldsmith, J., Rundle, A. G., Baccarelli, A. A., Herbstman, J. B., & Kupsco, A. (2023). Negative Associations of Cord Blood Mitochondrial DNA Copy Number with Childhood Adiposity Trajectories in Children. ISEE Conference Abstracts, 2023(1). https://doi.org/10.1289/isee.2023.mp-037
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Brickman, A. M., Yeung, L.-K., Alschuler, D. M., Ottaviani, J. I., Kuhnle, G. G. C., Sloan, R. P., Luttmann-Gibson, H., Copeland, T., Schroeter, H., Sesso, H. D., Manson, J. E., Wall, M., & Small, S. A. (2023). Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and lower habitual flavanol consumption. Proceedings of the National Academy of Sciences, 120(23). https://doi.org/10.1073/pnas.2216932120
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Shi, H., Prough, R. A., McClain, C. J., & Song, M. (2023). Different Types of Dietary Fat and Fructose Interactions Result in Distinct Metabolic Phenotypes in Male Mice. The Journal of Nutritional Biochemistry, 111, 109189. https://doi.org/10.1016/j.jnutbio.2022.109189
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Richter, L. R., Albert, B. I., Zhang, L., Ostropolets, A., Zitsman, J. L., Fennoy, I., Albers, D. J., & Hripcsak, G. (2022). Data assimilation on mechanistic models of glucose metabolism predicts glycemic states in adolescents following bariatric surgery. Frontiers in Physiology, 13. https://doi.org/10.3389/fphys.2022.923704
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Blackett, J. W., Sun, Y., Purpura, L., Margolis, K. G., Elkind, M. S. V., O’Byrne, S., Wainberg, M., Abrams, J. A., Wang, H. H., Chang, L., & Freedberg, D. E. (2022). DECREASED GUT MICROBIOME TRYPTOPHAN METABOLISM AND SEROTONERGIC SIGNALING IN PATIENTS WITH PERSISTENT MENTAL HEALTH AND GASTROINTESTINAL SYMPTOMS AFTER COVID-19. Clinical and Translational Gastroenterology. https://doi.org/10.14309/ctg.0000000000000524
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Striano, P., Auvin, S., Collins, A., Horvath, R., Scheffer, I. E., Tzadok, M., Miller, I., Kay Koenig, M., Lacy, A., Davis, R., Garcia‐Cazorla, A., Saneto, R. P., Brandabur, M., Blair, S., Koutsoukos, T., & De Vivo, D. (2022). A randomized, double‐blind trial of triheptanoin for drug‐resistant epilepsy in glucose transporter 1 deficiency syndrome. Epilepsia, 63(7), 1748–1760. Portico. https://doi.org/10.1111/epi.17263
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Lauren, B. N., Lim, F., Krikhely, A., Taveras, E. M., Woo Baidal, J. A., Bellows, B. K., & Hur, C. (2022). Estimated Cost-effectiveness of Medical Therapy, Sleeve Gastrectomy, and Gastric Bypass in Patients With Severe Obesity and Type 2 Diabetes. JAMA Network Open, 5(2), e2148317. https://doi.org/10.1001/jamanetworkopen.2021.48317
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Prasad, M., Mark, V., Ligon, C., Dutia, R., Nair, N., Shah, A., & Laferrère, B. (2021). Role of the Gut in the Temporal Changes of β-Cell Function After Gastric Bypass in Individuals With and Without Diabetes Remission. Diabetes Care, 45(2), 469–476. https://doi.org/10.2337/dc21-1270
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Popp, C. J., Curran, M., Wang, C., Prasad, M., Fine, K., Gee, A., Nair, N., Perdomo, K., Chen, S., Hu, L., St-Jules, D. E., Manoogian, E. N. C., Panda, S., Sevick, M. A., & Laferrère, B. (2021). Temporal Eating Patterns and Eating Windows among Adults with Overweight or Obesity. Nutrients, 13(12), 4485. https://doi.org/10.3390/nu13124485
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