HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide

Wang, S., Matassoli, F., Zhang, B., Liu, T., Shen, C.-H., Bylund, T., Johnston, T., Henry, A. R., Teng, I.-T., Tripathi, P., Becker, J. E., Changela, A., Chaudhary, R., Cheng, C., Gaudinski, M., Gorman, J., Harris, D. R., Lee, M., Morano, N. C., … Kwong, P. D. (2023). HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide. Cell Reports, 42(7), 112755. https://doi.org/10.1016/j.celrep.2023.112755
Authors:
Shuishu Wang
Flavio Matassoli
Baoshan Zhang
Tracy Liu
Chen-Hsiang Shen
Tatsiana Bylund
Timothy Johnston
Amy R Henry
I-Ting Teng
Prabhanshu Tripathi
Jordan E Becker
Anita Changela
Ridhi Chaudhary
Cheng Cheng
Martin Gaudinski
Jason Gorman
Darcy R Harris
Myungjin Lee
Nicholas C Morano
Laura Novik
Sijy O'Dell
Adam S Olia
Danealle K Parchment
Reda Rawi
Jesmine Roberts-Torres
Tyler Stephens
Yaroslav Tsybovsky
Danyi Wang
David J Van Wazer
Tongqing Zhou
Nicole A Doria-Rose
Richard A Koup
Lawrence Shapiro
Daniel C Douek
Adrian B McDermott
Peter D Kwong
Affiliated Authors:
Jordan E Becker
Nicholas C Morano
Lawrence Shapiro
Peter D Kwong
Columbia Affiliation:
Subjects:
AIDS Vaccines (MeSH)
HIV Infections (MeSH)
HIV Seropositivity (MeSH)
HIV-1 (MeSH)
Author Keywords:
antibody-antigen binding
cp: immunology
cryo-em structure
envelope trimer
fusion peptide
glycan hole
hiv vaccine
immunogen design
reproducible antibody class
site of vulnerability
elink
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2023.112755
PMID:
37436899
DOI:
10.1016/j.celrep.2023.112755
Journal:
Cell Reports
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record

Record Created: