Taub Institute for Research on Alzheimer’s Disease and the Aging Brain

Displaying 951 - 988 of 988CSV
Neitzel, J., Franzmeier, N., Rubinski, A., Dichgans, M., Brendel, M., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Liu, E., … Ewers, M. (2021). KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-23755-z
Publication Date
Gazes, Y., Li, R., Mensing, A., Babukutty, R. S., Noofoory, D., Nazario, G. H., Langfield, C., Sakhardande, J., & Lee, S. (2021). White matter fiber density for vocabulary better maintained than fluid abilities in aging. Alzheimer’s & Dementia, 17(S4). Portico. https://doi.org/10.1002/alz.055582
Publication Date
Hu, W. T., Ozturk, T., Kollhoff, A., Wharton, W., Christina Howell, J., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Perrin, R. J., Shaw, L. M., … Chiang, G. (2021). Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24220-7
Publication Date
de Jong, J. O., Llapashtica, C., Genestine, M., Strauss, K., Provenzano, F., Sun, Y., Zhu, H., Cortese, G. P., Brundu, F., Brigatti, K. W., Corneo, B., Migliori, B., Tomer, R., Kushner, S. A., Kellendonk, C., Javitch, J. A., Xu, B., & Markx, S. (2021). Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24358-4
Publication Date
Gonneaud, J., Baria, A. T., Pichet Binette, A., Gordon, B. A., Chhatwal, J. P., Cruchaga, C., Jucker, M., Levin, J., Salloway, S., Farlow, M., Gauthier, S., Benzinger, T. L. S., Morris, J. C., Bateman, R. J., Breitner, J. C. S., Poirier, J., Vachon-Presseau, E., Villeneuve, S., … Vachon-Presseau, E. (2021). Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-25492-9
Publication Date
Manyisa, N., Schrauwen, I., de Souza Rios, L. A., Mowla, S., Tekendo-Ngongang, C., Popel, K., Esoh, K., Bharadwaj, T., Nouel-Saied, L. M., Acharya, A., Nasir, A., Wonkam-Tingang, E., Kock, C. de, Dandara, C., Leal, S. M., & Wonkam, A. (2021). A Monoallelic Variant in REST Is Associated with Non-Syndromic Autosomal Dominant Hearing Impairment in a South African Family. Genes, 12(11), 1765. https://doi.org/10.3390/genes12111765
Publication Date
Ng, B., Casazza, W., Kim, N. H., Wang, C., Farhadi, F., Tasaki, S., Bennett, D. A., De Jager, P. L., Gaiteri, C., & Mostafavi, S. (2021). Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants. PLOS Genetics, 17(11), e1009918. https://doi.org/10.1371/journal.pgen.1009918
Publication Date
Clouston, S. A. P., Hall, C. B., Kritikos, M., Bennett, D. A., DeKosky, S., Edwards, J., Finch, C., Kreisl, W. C., Mielke, M., Peskind, E. R., Raskind, M., Richards, M., Sloan, R. P., Spiro, A., Vasdev, N., Brackbill, R., Farfel, M., Horton, M., Lowe, S., … Luft, B. J. (2021). Cognitive impairment and World Trade Centre-related exposures. Nature Reviews Neurology, 18(2), 103–116. https://doi.org/10.1038/s41582-021-00576-8
Publication Date
Pohl, D. J., Seblova, D., Avila, J. F., Dorsman, K. A., Kulick, E. R., Casey, J. A., & Manly, J. (2021). Relationship between Residential Segregation, Later-Life Cognition, and Incident Dementia across Race/Ethnicity. International Journal of Environmental Research and Public Health, 18(21), 11233. https://doi.org/10.3390/ijerph182111233
Publication Date
Estrella, B., Liu, Y., Ricker, E. C., Pazos, M. A., Fiorito, J., Zuccarello, E., Calcagno, E., Honig, B., Arancio, O., & Amengual, J. E. (2021). Histone Acetyltransferase (HAT) Activator, YF2, Modulates the p53:BCL6 Axis and Antigen Presentation in Diffuse Large B-Cell Lymphomas. Blood, 138(Supplement 1), 2254–2254. https://doi.org/10.1182/blood-2021-151442
Publication Date
Lagomarsino, V. N., Pearse, R. V., Liu, L., Hsieh, Y.-C., Fernandez, M. A., Vinton, E. A., Paull, D., Felsky, D., Tasaki, S., Gaiteri, C., Vardarajan, B., Lee, H., Muratore, C. R., Benoit, C. R., Chou, V., Fancher, S. B., He, A., Merchant, J. P., Duong, D. M., … Young-Pearse, T. L. (2021). Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron, 109(21), 3402-3420.e9. https://doi.org/10.1016/j.neuron.2021.08.003
Publication Date
Blaudin de Thé, F.-X., Lassus, B., Schaler, A. W., Fowler, S. L., Goulbourne, C. N., Jeggo, R., Mannoury la Cour, C., Millan, M. J., & Duff, K. E. (2021). P62 accumulates through neuroanatomical circuits in response to tauopathy propagation. Acta Neuropathologica Communications, 9(1). https://doi.org/10.1186/s40478-021-01280-w
Publication Date
Weerts, M. J. A., Lanko, K., Guzmán-Vega, F. J., Jackson, A., Ramakrishnan, R., Cardona-Londoño, K. J., Peña-Guerra, K. A., van Bever, Y., van Paassen, B. W., Kievit, A., van Slegtenhorst, M., Allen, N. M., Kehoe, C. M., Robinson, H. K., Pang, L., Banu, S. H., Zaman, M., Efthymiou, S., Houlden, H., … Barakat, T. S. (2021). Delineating the molecular and phenotypic spectrum of the SETD1B-related syndrome. Genetics in Medicine, 23(11), 2122–2137. https://doi.org/10.1038/s41436-021-01246-2
Publication Date
Kobayashi, L. C., Gross, A. L., Gibbons, L. E., Tommet, D., Sanders, R. E., Choi, S.-E., Mukherjee, S., Glymour, M., Manly, J. J., Berkman, L. F., Crane, P. K., Mungas, D. M., & Jones, R. N. (2020). You Say Tomato, I Say Radish: Can Brief Cognitive Assessments in the U.S. Health Retirement Study Be Harmonized With Its International Partner Studies? The Journals of Gerontology: Series B, 76(9), 1767–1776. https://doi.org/10.1093/geronb/gbaa205
Publication Date
Hirsch, S. D., Elling, C. L., Bootpetch, T. C., Scholes, M. A., Hafrén, L., Streubel, S.-O., Pine, H. S., Wine, T. M., Szeremeta, W., Prager, J. D., Einarsdottir, E., Yousaf, A., Baschal, E. E., Rehman, S., Bamshad, M. J., Nickerson, D. A., Riazuddin, S., Leal, S. M., Ahmed, Z. M., … Santos-Cortez, R. L. P. (2021). The role of CDHR3 in susceptibility to otitis media. Journal of Molecular Medicine, 99(11), 1571–1583. https://doi.org/10.1007/s00109-021-02118-7
Publication Date
Santiago-Torres, M., Contento, I., Koch, P., Tsai, W.-Y., Brickman, A. M., Gaffney, A. O., Thomson, C. A., Crane, T. E., Dominguez, N., Sepulveda, J., Marín-Chollom, A. M., Paul, R., Shi, Z., Ulanday, K. T., Hale, C., Hershman, D., & Greenlee, H. (2021). ¡Mi Vida Saludable! A randomized, controlled, 2 × 2 factorial trial of a diet and physical activity intervention among Latina breast cancer survivors: Study design and methods. Contemporary Clinical Trials, 110, 106524. https://doi.org/10.1016/j.cct.2021.106524
Publication Date
Cook, L., Schulze, J., Verbrugge, J., Beck, J. C., Marder, K. S., Saunders-Pullman, R., Klein, C., Naito, A., Alcalay, R. N., Brice, A., Kumeh, A., West, A. B., Singleton, A., Naito, A., Schüle, B., Fiske, B., Gabbert, C., Klein, C., Marras, C., … Bonifati, V. (2021). The commercial genetic testing landscape for Parkinson’s disease. Parkinsonism & Related Disorders, 92, 107–111. https://doi.org/10.1016/j.parkreldis.2021.10.001
Publication Date
Xie, Z., Sun, C., Liu, Y., Yu, M., Zheng, Y., Meng, L., Wang, G., Cornejo-Sanchez, D. M., Bharadwaj, T., Yan, J., Zhang, L., Pineda-Trujillo, N., Zhang, W., Leal, S. M., Schrauwen, I., Wang, Z., & Yuan, Y. (2020). Practical approach to the genetic diagnosis of unsolved dystrophinopathies: a stepwise strategy in the genomic era. Journal of Medical Genetics, 58(11), 743–751. https://doi.org/10.1136/jmedgenet-2020-107113
Publication Date
Tropea, M. R., Li Puma, D. D., Melone, M., Gulisano, W., Arancio, O., Grassi, C., Conti, F., & Puzzo, D. (2021). Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer’s disease-like pathology. Progress in Neurobiology, 206, 102154. https://doi.org/10.1016/j.pneurobio.2021.102154
Publication Date
Siddiqui, T., Bhattarai, P., Popova, S., Cosacak, M. I., Sariya, S., Zhang, Y., Mayeux, R., Tosto, G., & Kizil, C. (2021). KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer’s Disease. Cells, 10(10), 2748. https://doi.org/10.3390/cells10102748
Publication Date
Zaheed, A. B., Sharifian, N., Kraal, A. Z., Sol, K., Manly, J. J., Schupf, N., Brickman, A. M., & Zahodne, L. B. (2020). Mediators and Moderators of the Association Between Perceived Stress and Episodic Memory in Diverse Older Adults. Journal of the International Neuropsychological Society, 27(9), 883–895. https://doi.org/10.1017/s1355617720001253
Publication Date
Qiao, L., Xu, L., Yu, L., Wynn, J., Hernan, R., Zhou, X., Farkouh-Karoleski, C., Krishnan, U. S., Khlevner, J., De, A., Zygmunt, A., Crombleholme, T., Lim, F.-Y., Needelman, H., Cusick, R. A., Mychaliska, G. B., Warner, B. W., Wagner, A. J., Danko, M. E., … Chung, W. K. (2021). Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene. The American Journal of Human Genetics, 108(10), 1964–1980. https://doi.org/10.1016/j.ajhg.2021.08.011
Publication Date
Rizvi, B., Lao, P. J., Chesebro, A. G., Dworkin, J. D., Amarante, E., Beato, J. M., Gutierrez, J., Zahodne, L. B., Schupf, N., Manly, J. J., Mayeux, R., & Brickman, A. M. (2021). Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults. JAMA Network Open, 4(10), e2125166. https://doi.org/10.1001/jamanetworkopen.2021.25166
Publication Date
D’Gama, P. P., Qiu, T., Cosacak, M. I., Rayamajhi, D., Konac, A., Hansen, J. N., Ringers, C., Acuña-Hinrichsen, F., Hui, S. P., Olstad, E. W., Chong, Y. L., Lim, C. K. A., Gupta, A., Ng, C. P., Nilges, B. S., Kashikar, N. D., Wachten, D., Liebl, D., Kikuchi, K., … Jurisch-Yaksi, N. (2021). Diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain. Cell Reports, 37(1), 109775. https://doi.org/10.1016/j.celrep.2021.109775
Publication Date
Vonk, J. M. J., Greving, J. P., Gudnason, V., Launer, L. J., & Geerlings, M. I. (2021). Dementia risk in the general population: large-scale external validation of prediction models in the AGES-Reykjavik study. European Journal of Epidemiology, 36(10), 1025–1041. https://doi.org/10.1007/s10654-021-00785-x
Publication Date
Stern, Y., Stallard, E., Kinosian, B., Zhu, C., Cosentino, S., Jin, Z., & Gu, Y. (2021). Validation and demonstration of a new comprehensive model of Alzheimer’s disease progression. Alzheimer’s & Dementia, 17(10), 1698–1708. Portico. https://doi.org/10.1002/alz.12336
Publication Date
Vlachos, G. S., Kosmidis, M. H., Yannakoulia, M., Dardiotis, E., Hadjigeorgiou, G., Tzoulaki, I., Georgiou, A. N., Sakka, P., Anastasiou, C. A., Stefanis, L., & Scarmeas, N. (2021). Incidence of mild cognitive impairment in the elderly population in Greece: results from the HELIAD study. Aging Clinical and Experimental Research, 33(10), 2679–2688. https://doi.org/10.1007/s40520-021-01819-w
Publication Date
Monteiro-Fernandes, D., Silva, J. M., Soares-Cunha, C., Dalla, C., Kokras, N., Arnaud, F., Billiras, R., Zhuravleva, V., Waites, C., Bretin, S., Sousa, N., & Sotiropoulos, I. (2020). Allosteric modulation of AMPA receptors counteracts Tau-related excitotoxic synaptic signaling and memory deficits in stress- and Aβ-evoked hippocampal pathology. Molecular Psychiatry, 26(10), 5899–5911. https://doi.org/10.1038/s41380-020-0794-5
Publication Date
Damotte, V., van der Lee, S. J., Chouraki, V., Grenier‐Boley, B., Simino, J., Adams, H., Tosto, G., White, C., Terzikhan, N., Cruchaga, C., Knol, M. J., Li, S., Schraen, S., Grove, M. L., Satizabal, C., Amin, N., Berr, C., Younkin, S., … van Duijn, C. M. (2021). Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12,000 non‐demented participants. Alzheimer’s & Dementia, 17(10), 1663–1674. Portico. https://doi.org/10.1002/alz.12333
Publication Date
Qiao, Y. (Susanna), Gmelin, T., Renner, S. W., Boudreau, R. M., Martin, S., Wojczynski, M. K., Christensen, K., Andersen, S. L., Cosentino, S., Santanasto, A. J., & Glynn, N. W. (2020). Evaluation of the Bidirectional Relations of Perceived Physical Fatigability and Physical Activity on Slower Gait Speed. The Journals of Gerontology: Series A, 76(10), e237–e244. https://doi.org/10.1093/gerona/glaa281
Publication Date
Acharya, A., Raza, S. I., Anwar, M. Z., Bharadwaj, T., Liaqat, K., Khokhar, M. A. S., Everard, J. L., Nasir, A., Nickerson, D. A., Bamshad, M. J., Ansar, M., Schrauwen, I., Ahmad, W., & Leal, S. M. (2021). Wolfram-like syndrome with bicuspid aortic valve due to a homozygous missense variant in CDK13. Journal of Human Genetics, 66(10), 1009–1018. https://doi.org/10.1038/s10038-021-00922-0
Publication Date
Louis, E. D., Huey, E. D., & Cosentino, S. (2021). Features of “ET plus” correlate with age and tremor duration: “ET plus” may be a disease stage rather than a subtype of essential tremor. Parkinsonism & Related Disorders, 91, 42–47. https://doi.org/10.1016/j.parkreldis.2021.08.017
Publication Date
Deri, Y., Clouston, S. A. P., DeLorenzo, C., Gardus, J. D., Bartlett, E. A., Santiago-Michels, S., Bangiyev, L., Kreisl, W. C., Kotov, R., Huang, C., Slifstein, M., Parsey, R. V., & Luft, B. J. (2021). Neuroinflammation in World Trade Center responders at midlife: A pilot study using [18F]-FEPPA PET imaging. Brain, Behavior, & Immunity - Health, 16, 100287. https://doi.org/10.1016/j.bbih.2021.100287
Publication Date