Li, S., Bhattacharya, S., Chou, C.-Y., Chu, M., Chou, S.-C., Tonelli, M., Goger, M., Yang, H., Palmer, A. G., & Cavagnero, S. (2024). LC-Photo-CIDNP hyperpolarization of biomolecules bearing a quasi-isolated spin pair: Magnetic-Field dependence via a rapid-shuttling device. Journal of Magnetic Resonance, 359, 107616. https://doi.org/10.1016/j.jmr.2023.107616

Bhattacharjee, S., Feng, X., Maji, S., Dadhwal, P., Zhang, Z., Brown, Z. P., & Frank, J. (2024). Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187(3), 782-796.e23. https://doi.org/10.1016/j.cell.2023.12.027

Papa, A., del Rivero Morfin, P. J., Chen, B.-X., Yang, L., Katchman, A. N., Zakharov, S. I., Liu, G., Bohnen, M. S., Zheng, V., Katz, M., Subramaniam, S., Hirsch, J. A., Weiss, S., Dascal, N., Karlin, A., Pitt, G. S., Colecraft, H. M., Ben-Johny, M., & Marx, S. O. (2024). A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels. Journal of Clinical Investigation, 134(5). https://doi.org/10.1172/jci176943

Acosta-Reyes, F. J., Bhattacharjee, S., Gottesman, M., & Frank, J. (2024). How Dedicated Ribosomes Translate a Leaderless mRNA. Journal of Molecular Biology, 436(4), 168423. https://doi.org/10.1016/j.jmb.2023.168423

Lampe, G. D., King, R. T., Halpin-Healy, T. S., Klompe, S. E., Hogan, M. I., Vo, P. L. H., Tang, S., Chavez, A., & Sternberg, S. H. (2023). Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases. Nature Biotechnology, 42(1), 87–98. https://doi.org/10.1038/s41587-023-01748-1

Bastard, P., Vazquez, S. E., Liu, J., Laurie, M. T., Wang, C. Y., Gervais, A., Le Voyer, T., Bizien, L., Zamecnik, C., Philippot, Q., Rosain, J., Catherinot, E., Willmore, A., Mitchell, A. M., Bair, R., Garçon, P., Kenney, H., Fekkar, A., … Salagianni, M. (2023). Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs. Science Immunology, 8(90). https://doi.org/10.1126/sciimmunol.abp8966

Geng, A., Ganser, L., Roy, R., Shi, H., Pratihar, S., Case, D. A., & Al-Hashimi, H. M. (2023). An RNA excited conformational state at atomic resolution. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-43673-6

Pourmorady, A. D., Bashkirova, E. V., Chiariello, A. M., Belagzhal, H., Kodra, A., Duffié, R., Kahiapo, J., Monahan, K., Pulupa, J., Schieren, I., Osterhoudt, A., Dekker, J., Nicodemi, M., & Lomvardas, S. (2023). RNA-mediated symmetry breaking enables singular olfactory receptor choice. Nature, 625(7993), 181–188. https://doi.org/10.1038/s41586-023-06845-4

Bhai, L., Thomas, J. K., Conroy, D. W., Xu, Y., Al-Hashimi, H. M., & Jaroniec, C. P. (2023). Hydrogen bonding in duplex DNA probed by DNP enhanced solid-state NMR N-H bond length measurements. Frontiers in Molecular Biosciences, 10. https://doi.org/10.3389/fmolb.2023.1286172

Bashkirova, E. V., Klimpert, N., Monahan, K., Campbell, C. E., Osinski, J., Tan, L., Schieren, I., Pourmorady, A., Stecky, B., Barnea, G., Xie, X. S., Abdus-Saboor, I., Shykind, B. M., Marlin, B. J., Gronostajski, R. M., Fleischmann, A., & Lomvardas, S. (2023). Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice. ELife, 12. CLOCKSS. https://doi.org/10.7554/elife.87445

Banerjee, D., Boboila, S., Okochi, S., Angelastro, J. M., Kadenhe-Chiweshe, A. V., Lopez, G., Califano, A., Connolly, E. P., Greene, L. A., & Yamashiro, D. J. (2023). Activating Transcription Factor 5 Promotes Neuroblastoma Metastasis by Inducing Anoikis Resistance. Cancer Research Communications, 3(12), 2518–2530. https://doi.org/10.1158/2767-9764.crc-23-0154

Meir, A., Raina, V. B., Rivera, C. E., Marie, L., Symington, L. S., & Greene, E. C. (2023). The separation pin distinguishes the pro– and anti–recombinogenic functions of Saccharomyces cerevisiae Srs2. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-43918-4

Stokes, M. E., Vasciaveo, A., Small, J. C., Zask, A., Reznik, E., Smith, N., Wang, Q., Daniels, J., Forouhar, F., Rajbhandari, P., Califano, A., & Stockwell, B. R. (2024). Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers. Cell Chemical Biology, 31(4), 805-819.e9. https://doi.org/10.1016/j.chembiol.2023.11.007

Smith, N., Reznik, E., Bisikirska, B., Polychronidou, V., Wang, Q., Zask, A., Forouhar, F., Califano, A., & Stockwell, B. R. (2023). Kinases Controlling Stability of the Oncogenic MYCN Protein. ACS Medicinal Chemistry Letters, 14(12), 1664–1672. https://doi.org/10.1021/acsmedchemlett.3c00274

Kostyrko, K., Román, M., Lee, A. G., Simpson, D. R., Dinh, P. T., Leung, S. G., Marini, K. D., Kelly, M. R., Broyde, J., Califano, A., Jackson, P. K., & Sweet-Cordero, E. A. (2023). UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39591-2

Al-Dalahmah, O., Argenziano, M. G., Kannan, A., Mahajan, A., Furnari, J., Paryani, F., Boyett, D., Save, A., Humala, N., Khan, F., Li, J., Lu, H., Sun, Y., Tuddenham, J. F., Goldberg, A. R., Dovas, A., Banu, M. A., Sudhakar, T., Bush, E., … Canoll, P. (2023). Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-38186-1

Sturm, G., Karan, K. R., Monzel, A. S., Santhanam, B., Taivassalo, T., Bris, C., Ware, S. A., Cross, M., Towheed, A., Higgins-Chen, A., McManus, M. J., Cardenas, A., Lin, J., Epel, E. S., Rahman, S., Vissing, J., Grassi, B., Levine, M., Horvath, S., … Picard, M. (2023). OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases. Communications Biology, 6(1). https://doi.org/10.1038/s42003-022-04303-x

Vukolova, M. N., Yen, L. Y., Khmyz, M. I., Sobolevsky, A. I., & Yelshanskaya, M. V. (2023). Parkinson’s disease, epilepsy, and amyotrophic lateral sclerosis—emerging role of AMPA and kainate subtypes of ionotropic glutamate receptors. Frontiers in Cell and Developmental Biology, 11. https://doi.org/10.3389/fcell.2023.1252953

Matassoli, F., Cagigi, A., Shen, C.-H., Henry, A. R., Johnston, T. S., Schramm, C. A., Cottrell, C. A., Kalyuzhniy, O., Spangler, A., Ndung’u, T., Dong, K., Eller, L., Robb, M., Eller, M., Naluyima, P., Kwong, P. D., Douek, D. C., Schief, W. R., Andrews, S. F., & McDermott, A. B. (2023). High frequency of HIV precursor-target-specific B cells in sub-Saharan populations. Cell Reports, 42(12), 113450. https://doi.org/10.1016/j.celrep.2023.113450

Mendez, J. H., Chua, E. Y. D., Paraan, M., Potter, C. S., & Carragher, B. (2023). Automated pipelines for rapid evaluation during cryoEM data acquisition. Current Opinion in Structural Biology, 83, 102729. https://doi.org/10.1016/j.sbi.2023.102729

Korn, S. M., Sharma, S., & Steckelberg, A.-L. (2024). The ART of RNAylation: covalent RNA–protein linkage in bacteriophage infection. Trends in Biochemical Sciences, 49(2), 97–98. https://doi.org/10.1016/j.tibs.2023.10.011

George, J. T., Acree, C., Park, J.-U., Kong, M., Wiegand, T., Pignot, Y. L., Kellogg, E. H., Greene, E. C., & Sternberg, S. H. (2023). Mechanism of target site selection by type V-K CRISPR-associated transposases. Science, 382(6672). https://doi.org/10.1126/science.adj8543

Goff, S. P., & Shenk, T. (2023). Paul Berg: Recombinant DNA trailblazer. Proceedings of the National Academy of Sciences, 120(47). https://doi.org/10.1073/pnas.2318196120

Banerjee, P. R., Holehouse, A. S., Kriwacki, R., Robustelli, P., Jiang, H., Sobolevsky, A. I., Hurley, J. M., & Mendell, J. T. (2024). Dissecting the biophysics and biology of intrinsically disordered proteins. Trends in Biochemical Sciences, 49(2), 101–104. https://doi.org/10.1016/j.tibs.2023.10.002

Braun, J., Neme, R., Feng, Y., Landweber, L. F., & Jonoska, N. (2023). SDRAP for annotating scrambled or rearranged genomes. NAR Genomics and Bioinformatics, 5(4). https://doi.org/10.1093/nargab/lqad096

Li, Z., Duan, S., Hua, X., Xu, X., Li, Y., Menolfi, D., Zhou, H., Lu, C., Zha, S., Goff, S. P., & Zhang, Z. (2023). Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements. Nature, 623(7987), 643–651. https://doi.org/10.1038/s41586-023-06711-3

Juen, Z., Villavicencio, M., & Zuker, C. S. (2024). A neural substrate for short-term taste memories. Neuron, 112(2), 277-287.e4. https://doi.org/10.1016/j.neuron.2023.10.009

Varkaris, A., Pazolli, E., Gunaydin, H., Wang, Q., Pierce, L., Boezio, A. A., Bulku, A., DiPietro, L., Fridrich, C., Frost, A., Giordanetto, F., Hamilton, E. P., Harris, K., Holliday, M., Hunter, T. L., Iskandar, A., Ji, Y., Larivée, A., LaRochelle, J. R., … Kipp, D. R. (2023). Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia. Cancer Discovery, 14(2), 240–257. https://doi.org/10.1158/2159-8290.cd-23-0944

Cherng, H.-J. J., Yang, X., Yancey, R., Gordillo, C. A., Piorczynski, T. B., Chan, H. T., Ofori, K. N., Bhagat, G., Califano, A., Pro, B., Booher, K., Amengual, J. E., Reshef, R., & Sina, A. A. I. (2023). Methylated Whole Genome Cell-Free DNA Sequencing before Chimeric Antigen Receptor T-Cell Therapy for Large B-Cell Lymphoma Predicts Treatment Outcomes. Blood, 142(Supplement 1), 4371–4371. https://doi.org/10.1182/blood-2023-178376

Hawley, J. E., Obradovic, A. Z., Dallos, M. C., Lim, E. A., Runcie, K., Ager, C. R., McKiernan, J., Anderson, C. B., Decastro, G. J., Weintraub, J., Virk, R., Lowy, I., Hu, J., Chaimowitz, M. G., Guo, X. V., Zhang, Y., Haffner, M. C., Worley, J., Stein, M. N., … Drake, C. G. (2023). Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer. Cancer Cell, 41(11), 1972-1988.e5. https://doi.org/10.1016/j.ccell.2023.10.006

Tang, S., & Sternberg, S. H. (2023). Genome editing with retroelements. Science, 382(6669), 370–371. https://doi.org/10.1126/science.adi3183

Dorrity, T. J., Shin, H., Wiegand, K. A., Aruda, J., Closser, M., Jung, E., Gertie, J. A., Leone, A., Polfer, R., Culbertson, B., Yu, L., Wu, C., Ito, T., Huang, Y., Steckelberg, A.-L., Wichterle, H., & Chung, H. (2023). Long 3′UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation. Science Immunology, 8(88). https://doi.org/10.1126/sciimmunol.adg2979

Neuberger, A., & Sobolevsky, A. I. (2023). Molecular pharmacology of the onco-TRP channel TRPV6. Channels, 17(1). https://doi.org/10.1080/19336950.2023.2266669

Roy, R., Geng, A., Shi, H., Merriman, D. K., Dethoff, E. A., Salmon, L., & Al-Hashimi, H. M. (2023). Kinetic Resolution of the Atomic 3D Structures Formed by Ground and Excited Conformational States in an RNA Dynamic Ensemble. Journal of the American Chemical Society, 145(42), 22964–22978. https://doi.org/10.1021/jacs.3c04614

Neuberger, A., & Sobolevsky, A. I. (2023). Pentameric TRPV3: An artifact or a clue to channel function? Cell Calcium, 116, 102812. https://doi.org/10.1016/j.ceca.2023.102812

Hart, S. F. M., Yonemitsu, M. A., Giersch, R. M., Garrett, F. E. S., Beal, B. F., Arriagada, G., Davis, B. W., Ostrander, E. A., Goff, S. P., & Metzger, M. J. (2023). Centuries of genome instability and evolution in soft-shell clam, Mya arenaria, bivalve transmissible neoplasia. Nature Cancer, 4(11), 1561–1574. https://doi.org/10.1038/s43018-023-00643-7

Dugger, S. A., Dhindsa, R. S., Sampaio, G. D. A., Ressler, A. K., Rafikian, E. E., Petri, S., Letts, V. A., Teoh, J., Ye, J., Colombo, S., Peng, Y., Yang, M., Boland, M. J., Frankel, W. N., & Goldstein, D. B. (2023). Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency. PLOS Genetics, 19(10), e1010952. https://doi.org/10.1371/journal.pgen.1010952

Gangwar, S. P., Yen, L. Y., Yelshanskaya, M. V., Korman, A., Jones, D. R., & Sobolevsky, A. I. (2023). Modulation of GluA2–γ5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nature Structural & Molecular Biology, 30(10), 1481–1494. https://doi.org/10.1038/s41594-023-01080-x

Liu, L., Casner, R. G., Guo, Y., Wang, Q., Iketani, S., Chan, J. F.-Woo., Yu, J., Dadonaite, B., Nair, M. S., Mohri, H., Reddem, E. R., Yuan, S., Poon, V. K.-M., Chan, C. C.-S., Yuen, K.-Y., Sheng, Z., Huang, Y., Bloom, J. D., Shapiro, L., & Ho, D. D. (2023). Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking. Immunity, 56(10), 2442-2455.e8. https://doi.org/10.1016/j.immuni.2023.09.003

Taylor, A. M., Williams, B. R., Giordanetto, F., Kelley, E. H., Lescarbeau, A., Shortsleeves, K., Tang, Y., Walters, W. P., Arrazate, A., Bowman, C., Brophy, E., Chan, E. W., Deshmukh, G., Greisman, J. B., Hunsaker, T. L., Kipp, D. R., Saenz Lopez-Larrocha, P., Maddalo, D., Martin, I. J., … Willmore, L. (2023). Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors. Journal of Medicinal Chemistry, 66(19), 13384–13399. https://doi.org/10.1021/acs.jmedchem.3c00483

Meers, C., Le, H. C., Pesari, S. R., Hoffmann, F. T., Walker, M. W. G., Gezelle, J., Tang, S., & Sternberg, S. H. (2023). Transposon-encoded nucleases use guide RNAs to promote their selfish spread. Nature, 622(7984), 863–871. https://doi.org/10.1038/s41586-023-06597-1

Ou, L., Chen, S. J., Teng, I.-T., Yang, L., Zhang, B., Zhou, T., Biju, A., Cheng, C., Kong, W.-P., Morano, N. C., Stancofski, E.-S. D., Todd, J.-P., Tsybovsky, Y., Wang, S., Zheng, C.-Y., Mascola, J. R., Shapiro, L., Woodward, R. A., Buchholz, U. J., & Kwong, P. D. (2023). Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus. PLOS Pathogens, 19(9), e1011584. https://doi.org/10.1371/journal.ppat.1011584

Koldsø, H., Jensen, M. Ø., Jogini, V., & Shaw, D. E. (2023). Functional dynamics and allosteric modulation of TRPA1. Structure, 31(12), 1556-1566.e3. https://doi.org/10.1016/j.str.2023.08.018

Schaffer, E. S., Mishra, N., Whiteway, M. R., Li, W., Vancura, M. B., Freedman, J., Patel, K. B., Voleti, V., Paninski, L., Hillman, E. M. C., Abbott, L. F., & Axel, R. (2023). The spatial and temporal structure of neural activity across the fly brain. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-41261-2

Duan, Y., Zhou, H., Liu, X., Iketani, S., Lin, M., Zhang, X., Bian, Q., Wang, H., Sun, H., Hong, S. J., Culbertson, B., Mohri, H., Luck, M. I., Zhu, Y., Liu, X., Lu, Y., Yang, X., Yang, K., Sabo, Y., … Yang, H. (2023). Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature, 622(7982), 376–382. https://doi.org/10.1038/s41586-023-06609-0

Yu, J., Sreenivasan, C., Sheng, Z., Zhai, S.-L., Wollman, J. W., Luo, S., Huang, C., Gao, R., Wang, Z., Kaushik, R. S., Christopher-Hennings, J., Nelson, E., Hause, B. M., Li, F., & Wang, D. (2023). A recombinant chimeric influenza virus vaccine expressing the consensus H3 hemagglutinin elicits broad hemagglutination inhibition antibodies against divergent swine H3N2 influenza viruses. Vaccine, 41(42), 6318–6326. https://doi.org/10.1016/j.vaccine.2023.09.007

Nagendra, K., Izzet, A., Judd, N. B., Zakine, R., Friedman, L., Harrison, O. J., Pontani, L.-L., Shapiro, L., Honig, B., & Brujic, J. (2023). Push-pull mechanics of E-cadherin ectodomains in biomimetic adhesions. Biophysical Journal, 122(17), 3506–3515. https://doi.org/10.1016/j.bpj.2023.07.026

Hendrickson, W. A. (2023). Facing the phase problem. IUCrJ, 10(5), 521–543. https://doi.org/10.1107/s2052252523006449

Maurina, S. F., O’Sullivan, J. P., Sharma, G., Pineda Rodriguez, D. C., MacFadden, A., Cendali, F., Henen, M. A., Vögeli, B., Kieft, J. S., Glasgow, A., & Steckelberg, A.-L. (2023). An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by β-coronavirus Non-structural Protein 1. Journal of Molecular Biology, 435(20), 168259. https://doi.org/10.1016/j.jmb.2023.168259

Ager, C. R., Zhang, M., Chaimowitz, M., Bansal, S., Tagore, S., Obradovic, A., Jugler, C., Rogava, M., Melms, J. C., McCann, P., Spina, C., Drake, C. G., Dallos, M. C., & Izar, B. (2023). KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response. Journal for ImmunoTherapy of Cancer, 11(9), e006782. https://doi.org/10.1136/jitc-2023-006782