R01NS086736

NIH – National Institute of Neurological Disorders and Stroke

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Subjective Sleep Disturbance and Lewy Pathology: Data from a Cohort of Essential Tremor Brain Donors

Ghanem, A., Berry, D. S., Cosentino, S., Faust, P. L., & Louis, E. D. (2024). Subjective Sleep Disturbance and Lewy Pathology: Data from a Cohort of Essential Tremor Brain Donors. Neurodegenerative Diseases, 24(1), 6–15. Portico. https://doi.org/10.1159/000539032
Authors:
Ali Ghanem
Diane S Berry
Stephanie Cosentino
Phyllis L Faust
Elan D Louis
Affiliated Authors:
Stephanie Cosentino
Phyllis L Faust
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Sleep Wake Disorders (MeSH)
Brain (MeSH)
Author Keywords:
essential tremor
lewy pathology
locus coeruleus
pathophysiology
sleep disturbance
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1159/000539032
PMID:
38861955
DOI:
10.1159/000539032
Journal:
Neurodegenerative Diseases
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created:

Baseline Depressive Symptoms as a Predictor of Incident Dementia in a Prospectively Followed Cohort of Elders with Essential Tremor

Berry, D. S., Ghanem, A., McGurn, M. M., Huey, E. D., Cosentino, S., & Louis, E. D. (2024). Baseline Depressive Symptoms as a Predictor of Incident Dementia in a Prospectively Followed Cohort of Elders with Essential Tremor. Neurodegenerative Diseases, 24(2), 80–90. Portico. https://doi.org/10.1159/000540027
Authors:
Diane S Berry
Ali Ghanem
Margaret M McGurn
Edward D Huey
Stephanie Cosentino
Elan D Louis
Affiliated Authors:
Stephanie Cosentino
Columbia Affiliation:
Author Keywords:
clinical marker
dementia
depression
epidemiology
essential tremor
prospective study
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1159/000540027
PMID:
38981446
DOI:
10.1159/000540027
Journal:
Neurodegenerative Diseases
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created:

Prevalence of and Annual Conversion Rates to Mild Cognitive Impairment and Dementia: Prospective, Longitudinal Study of an Essential Tremor Cohort

Ghanem, A., Berry, D. S., Burkes, A., Grill, N., Hall, T. M., Hart, K. A., Hernandez, N. C., Chapman, S., Sharma, V. D., Huey, E. D., Cosentino, S. A., & Louis, E. D. (2024). Prevalence of and Annual Conversion Rates to Mild Cognitive Impairment and Dementia: Prospective, Longitudinal Study of an Essential Tremor Cohort. Annals of Neurology, 95(6), 1193–1204. Portico. https://doi.org/10.1002/ana.26927
Authors:
Ali Ghanem
Diane S Berry
Allison Burkes
Natalie Grill
Talía M Hall
Kira A Hart
Nora C Hernandez
Silvia Chapman
Vibhash D Sharma
Edward D Huey
Stephanie A Cosentino
Elan D Louis
Affiliated Authors:
Silvia Chapman
Stephanie A Cosentino
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Cognitive Dysfunction (MeSH)
Dementia (MeSH)
Disease Progression (MeSH)
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
T32NS007153 (NIH – National Institute of Neurological Disorders and Stroke)
U01AG079850 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1002/ana.26927
PMID:
38654628
DOI:
10.1002/ana.26927
Journal:
Annals of Neurology
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created:

Pathologically based criteria to distinguish essential tremor from controls: analyses of the human cerebellum

Faust, P. L., McCreary, M., Musacchio, J. B., Kuo, S., Vonsattel, J. G., & Louis, E. D. (2024). Pathologically based criteria to distinguish essential tremor from controls: analyses of the human cerebellum. Annals of Clinical and Translational Neurology, 11(6), 1514–1525. Portico. https://doi.org/10.1002/acn3.52068
Authors:
Phyllis L Faust
Morgan McCreary
Jessica B Musacchio
Sheng-Han Kuo
Jean-Paul G Vonsattel
Elan D Louis
Affiliated Authors:
Phyllis L Faust
Jessica B Musacchio
Sheng-Han Kuo
Jean-Paul G Vonsattel
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Cerebellum (MeSH)
Grants:
R01NS117745 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS088257 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1002/acn3.52068
PMID:
38644741
DOI:
10.1002/acn3.52068
Journal:
Annals of Clinical and Translational Neurology
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created:

Sleep problems as predictors of cognitive decline in essential tremor: A prospective longitudinal cohort study

Tsapanou, A., Ghanem, A., Chapman, S., Stern, Y., Huey, E. D., Cosentino, S., & Louis, E. D. (2024). Sleep problems as predictors of cognitive decline in essential tremor: A prospective longitudinal cohort study. Sleep Medicine, 116, 13–18. https://doi.org/10.1016/j.sleep.2024.02.016
Authors:
Angeliki Tsapanou
Ali Ghanem
Silvia Chapman
Yaakov Stern
Edward D Huey
Stephanie Cosentino
Elan D Louis
Affiliated Authors:
Angeliki Tsapanou
Silvia Chapman
Yaakov Stern
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Cognitive Dysfunction (MeSH)
Sleep Wake Disorders (MeSH)
Author Keywords:
essential tremor
sleep latency
cognitive decline
prospective study
longitudinal study
Grants:
R01MH120794 (NIH – National Institute of Mental Health)
T32NS007153 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
K99AG071930 (NIH – National Institute On Aging)
P30AG066462 (NIH – National Institute On Aging)
U01AG079850 (NIH – National Institute On Aging)
R01AG062268 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1016/j.sleep.2024.02.016
PMID:
38408421
DOI:
10.1016/j.sleep.2024.02.016
Journal:
Sleep Medicine
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created:

Reduced Bergmann glial process terminations and lateral appendages in essential tremor

Ruff, D. S., Balbo, I., Lai, R., Dieng, D., Hennessey, C., Vennam, K., Dwork, A. J., McCreary, M., Louis, E. D., Faust, P. L., & Kuo, S. (2023). Reduced Bergmann glial process terminations and lateral appendages in essential tremor. Annals of Clinical and Translational Neurology, 11(2), 377–388. Portico. https://doi.org/10.1002/acn3.51958
Authors:
David S Ruff
Ilaria Balbo
Ruo-Yah Lai
Diarra Dieng
Charlotte Hennessey
Krish Vennam
Andrew J Dwork
Morgan McCreary
Elan D Louis
Phyllis L Faust
Sheng-Han Kuo
Affiliated Authors:
David S Ruff
Ilaria Balbo
Ruo-Yah Lai
Diarra Dieng
Charlotte Hennessey
Krish Vennam
Andrew J Dwork
Phyllis L Faust
Sheng-Han Kuo
Columbia Affiliation:
Subjects:
Deep Brain Stimulation for Neurological Disorders (OpenAlex Topic)
Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders (OpenAlex Topic)
Adult Neurogenesis and Brain Development (OpenAlex Topic)
Essential Tremor (MeSH)
Grants:
R01NS118179 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS094607 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS124854 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS117745 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS104423 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1002/acn3.51958
PMID:
38098226
DOI:
10.1002/acn3.51958
Journal:
Annals of Clinical and Translational Neurology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
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Record Created:

Gene Expression Analysis of Laser-Captured Purkinje Cells in the Essential Tremor Cerebellum

Martuscello, R. T., Sivaprakasam, K., Hartstone, W., Kuo, S.-H., Konopka, G., Louis, E. D., & Faust, P. L. (2022). Gene Expression Analysis of Laser-Captured Purkinje Cells in the Essential Tremor Cerebellum. The Cerebellum, 22(6), 1166–1181. https://doi.org/10.1007/s12311-022-01483-4
Authors:
Regina T. Martuscello
Karthigayini Sivaprakasam
Whitney Hartstone
Sheng-Han Kuo
Genevieve Konopka
Elan D. Louis
Phyllis L. Faust
Affiliated Authors:
Regina T. Martuscello
Whitney Hartstone
Sheng-Han Kuo
Phyllis L. Faust
Columbia Affiliation:
Subjects:
Purkinje Cells (MeSH)
Essential Tremor (MeSH)
Author Keywords:
purkinje cell
rna-sequencing
essential tremor
laser capture microdissection
Grants:
R01HG011641 (NIH – National Human Genome Research Institute)
R01MH103517 (NIH – National Institute of Mental Health)
R01NS118179 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS124854 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS117745 (NIH – National Institute of Neurological Disorders and Stroke)
R21NS077094 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS094607 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS104423 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS088257 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1007/s12311-022-01483-4
PMID:
36242761
DOI:
10.1007/s12311-022-01483-4
Journal:
Cerebellum
Publication Date:
Data Source:
Scopus
Source Link:
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Record Created:

A prospective cohort study of familial versus sporadic essential tremor cases: Do clinical features evolve differently across time?

Berry, D. S., Cosentino, S., & Louis, E. D. (2023). A prospective cohort study of familial versus sporadic essential tremor cases: Do clinical features evolve differently across time? Journal of the Neurological Sciences, 454, 120854. https://doi.org/10.1016/j.jns.2023.120854
Authors:
Diane S Berry
Stephanie Cosentino
Elan D Louis
Affiliated Authors:
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Author Keywords:
clinical
cohort
essential tremor
family history
prospective
subtype
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1016/j.jns.2023.120854
PMID:
37924593
DOI:
10.1016/j.jns.2023.120854
Journal:
Journal of the Neurological Sciences
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created:

Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium 'leak' in tremor pathophysiology

Martuscello, R. T., Chen, M.-L., Reiken, S., Sittenfeld, L. R., Ruff, D. S., Ni, C.-L., Lin, C.-C., Pan, M.-K., Louis, E. D., Marks, A. R., Kuo, S.-H., & Faust, P. L. (2023). Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium ‘leak’ in tremor pathophysiology. Acta Neuropathologica, 146(2), 301–318. https://doi.org/10.1007/s00401-023-02602-z
Authors:
Regina T Martuscello
Meng-Ling Chen
Steven Reiken
Leah R Sittenfeld
David S Ruff
Chun-Lun Ni
Chih-Chun Lin
Ming-Kai Pan
Elan D Louis
Andrew R Marks
Sheng-Han Kuo
Phyllis L Faust
Affiliated Authors:
Regina T Martuscello
Meng-Ling Chen
Steven Reiken
Leah R Sittenfeld
David S Ruff
Chun-Lun Ni
Chih-Chun Lin
Andrew R Marks
Sheng-Han Kuo
Phyllis L Faust
Columbia Affiliation:
Subjects:
Ryanodine Receptor Calcium Release Channel (MeSH)
Calcium (MeSH)
Author Keywords:
calcium
cellular stress
cerebellum
essential tremor
mouse model
ryr1
Grants:
R01HL140934 (NIH – National Heart, Lung, and Blood Institute)
R25HL156002 (NIH – National Heart, Lung, and Blood Institute)
R01HL142903 (NIH – National Heart, Lung, and Blood Institute)
T32HL120826 (NIH – National Heart, Lung, and Blood Institute)
R01HL145473 (NIH – National Heart, Lung, and Blood Institute)
R01DK118240 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS118179 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS104423 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS117745 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS124854 (NIH – National Institute of Neurological Disorders and Stroke)
RF1NS114570 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS088257 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1007/s00401-023-02602-z
PMID:
37335342
DOI:
10.1007/s00401-023-02602-z
Journal:
Acta Neuropathologica
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record

Record Created:

Can the Montreal Cognitive Assessment and Mini-Mental State Examination detect cognitive decline in elderly patients with essential tremor?

McGurn, M., Dworkin, J. D., Chapman, S., Huey, E. D., Cosentino, S., & Louis, E. D. (2022). Can the Montreal Cognitive Assessment and Mini-Mental State Examination detect cognitive decline in elderly patients with essential tremor? The Clinical Neuropsychologist, 37(6), 1173–1190. https://doi.org/10.1080/13854046.2022.2090442
Authors:
Margaret McGurn
Jordan D Dworkin
Silvia Chapman
Edward D Huey
Stephanie Cosentino
Elan D Louis
Affiliated Authors:
Jordan D Dworkin
Silvia Chapman
Edward D Huey
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Cognitive Dysfunction (MeSH)
Author Keywords:
montreal cognitive assessment (moca)
mini-mental state examination (mmse)
cognitive decline
essential tremor
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
P30AG066462 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1080/13854046.2022.2090442
PMID:
35762453
DOI:
10.1080/13854046.2022.2090442
Journal:
Clinical Neuropsychologist
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created:

Associations between cognitive function and a range of significant life events in an elderly essential tremor cohort study

Berry, D. S., Nguyen, D., Cosentino, S., & Louis, E. D. (2023). Associations between cognitive function and a range of significant life events in an elderly essential tremor cohort study. Journal of the Neurological Sciences, 450, 120675. https://doi.org/10.1016/j.jns.2023.120675
Authors:
Diane S Berry
Diep Nguyen
Stephanie Cosentino
Elan D Louis
Affiliated Authors:
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Cognitive Dysfunction (MeSH)
Author Keywords:
cognition
essential tremor
executive function
falls
significant life events
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1016/j.jns.2023.120675
PMID:
37196573
DOI:
10.1016/j.jns.2023.120675
Journal:
Journal of the Neurological Sciences
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created:

Cognitive Performance as a Function of MAPT Haplotype: A Prospective Longitudinal Study of an Essential Tremor Cohort

Ghanem, A., Berry, D. S., Farrell, K., Cosentino, S., Crary, J. F., & Louis, E. D. (2023). Cognitive Performance as a Function of MAPT Haplotype: A Prospective Longitudinal Study of an Essential Tremor Cohort. Tremor and Other Hyperkinetic Movements, 13(1). https://doi.org/10.5334/tohm.768
Authors:
Ali Ghanem
Diane S Berry
Kurt Farrell
Stephanie Cosentino
John F Crary
Elan D Louis
Affiliated Authors:
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Deep Brain Stimulation for Neurological Disorders (OpenAlex Topic)
Molecular Basis of Rett Syndrome and Related Disorders (OpenAlex Topic)
Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders (OpenAlex Topic)
Dementia (MeSH)
Essential Tremor (MeSH)
Author Keywords:
mapt h1
cognition
dementia
essential tremor
genetic risk factors
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
RF1NS095252 (NIH – National Institute of Neurological Disorders and Stroke)
K01AG070326 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.5334/tohm.768
PMID:
37214541
DOI:
10.5334/tohm.768
Journal:
Tremor and Other Hyperkinetic Movements
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View OpenAlex Record

Record Created:

Histopathology of the cerebellar cortex in essential tremor and other neurodegenerative motor disorders: comparative analysis of 320 brains

Louis, E. D., Martuscello, R. T., Gionco, J. T., Hartstone, W. G., Musacchio, J. B., Portenti, M., McCreary, M., Kuo, S.-H., Vonsattel, J.-P. G., & Faust, P. L. (2023). Histopathology of the cerebellar cortex in essential tremor and other neurodegenerative motor disorders: comparative analysis of 320 brains. Acta Neuropathologica, 145(3), 265–283. https://doi.org/10.1007/s00401-022-02535-z
Authors:
Elan D Louis
Regina T Martuscello
John T Gionco
Whitney G Hartstone
Jessica B Musacchio
Marisa Portenti
Morgan McCreary
Sheng-Han Kuo
Jean-Paul G Vonsattel
Phyllis L Faust
Affiliated Authors:
Regina T Martuscello
John T Gionco
Whitney G Hartstone
Jessica B Musacchio
Marisa Portenti
Sheng-Han Kuo
Jean-Paul G Vonsattel
Phyllis L Faust
Columbia Affiliation:
Subjects:
Dystonia (MeSH)
Dystonic Disorders (MeSH)
Essential Tremor (MeSH)
Motor Disorders (MeSH)
Multiple System Atrophy (MeSH)
Parkinson Disease (MeSH)
Spinocerebellar Ataxias (MeSH)
Author Keywords:
cerebellum
dystonia
essential tremor
histopathology
neurodegenerative
spinocerebellar ataxia
Grants:
R01NS117745 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS124854 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS104423 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS088257 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS118179 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1007/s00401-022-02535-z
PMID:
36607423
DOI:
10.1007/s00401-022-02535-z
Journal:
Acta Neuropathologica
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created:

Lack of Familial Aggregation of the "Essential Tremor-Plus" Phenotype in Familial Essential Tremor

Berry, D. S., Hernandez, N., Clark, L. N., & Louis, E. D. (2022). Lack of Familial Aggregation of the “Essential Tremor-Plus” Phenotype in Familial Essential Tremor. Neuroepidemiology, 56(5), 373–379. Portico. https://doi.org/10.1159/000526278
Authors:
Diane S. Berry
Nora Hernandez
Lorraine N. Clark
Elan D. Louis
Affiliated Authors:
Lorraine N. Clark
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Family (MeSH)
Author Keywords:
essential tremor
epidemiology
genetic epidemiology
familial aggregation
clinical
essential tremor-plus
Grants:
R01NS073872 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1159/000526278
PMID:
35940165
DOI:
10.1159/000526278
Journal:
Neuroepidemiology
Publication Date:
Data Source:
Scopus
Source Link:
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Record Created:

Motor features associated with cognition in non-demented individuals with essential tremor

Peterson, A., Chapman, S., Iglesias-Hernandez, D., Tafader, M., Louis, E. D., & Cosentino, S. (2022). Motor features associated with cognition in non-demented individuals with essential tremor. Journal of the Neurological Sciences, 439, 120323. https://doi.org/10.1016/j.jns.2022.120323
Authors:
Amalia Peterson
Silvia Chapman
Daniella Iglesias-Hernandez
Marjana Tafader
Elan D. Louis
Stephanie Cosentino
Affiliated Authors:
Amalia Peterson
Silvia Chapman
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Author Keywords:
balance
cerebellum
cognition
essential tremor
gait
Grants:
R01NS117745 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
T32NS007153 (NIH – National Institute of Neurological Disorders and Stroke)
P30AG066462 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1016/j.jns.2022.120323
PMID:
35752130
DOI:
10.1016/j.jns.2022.120323
Journal:
Journal of the Neurological Sciences
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
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Record Created:

Depressive symptoms predict memory decline in Essential Tremor

Miller, J. R., Chapman, S., Hernandez, D. I., Radler, K., Delgado, N., Huey, E. D., Louis, E. D., & Cosentino, S. (2022). Depressive symptoms predict memory decline in Essential Tremor. Parkinsonism & Related Disorders, 98, 16–20. https://doi.org/10.1016/j.parkreldis.2022.03.013
Authors:
Jennifer R. Miller
Silvia Chapman
Daniella Iglesias Hernandez
Keith Radler
Nikki Delgado
Edward D. Huey
Elan D. Louis
Stephanie Cosentino
Affiliated Authors:
Silvia Chapman
Edward D. Huey
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Depression (MeSH)
Essential Tremor (MeSH)
Author Keywords:
essential tremor
depression
cognition
neurodegeneration
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
P30AG066462 (NIH – National Institute On Aging)
R01AG034618 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1016/j.parkreldis.2022.03.013
PMID:
35421780
DOI:
10.1016/j.parkreldis.2022.03.013
Journal:
Parkinsonism and Related Disorders
Publication Date:
Data Source:
Scopus
Source Link:
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Record Created:

Genome-wide association study and functional validation implicates JADE1 in tauopathy

Farrell, K., Kim, S., Han, N., Iida, M. A., Gonzalez, E. M., Otero-Garcia, M., Walker, J. M., Richardson, T. E., Renton, A. E., Andrews, S. J., Fulton-Howard, B., Humphrey, J., Vialle, R. A., Bowles, K. R., de Paiva Lopes, K., Whitney, K., Dangoor, D. K., Walsh, H., Marcora, E., … Crary, J. F. (2021). Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica, 143(1), 33–53. https://doi.org/10.1007/s00401-021-02379-z
Authors:
Kurt Farrell
SoongHo Kim
Natalia Han
Megan A. Iida
Elias M. Gonzalez
Marcos Otero-Garcia
Jamie M. Walker
Timothy E. Richardson
Alan E. Renton
Shea J. Andrews
Brian Fulton-Howard
Jack Humphrey
Ricardo A. Vialle
Kathryn R. Bowles
Katia de Paiva Lopes
Kristen Whitney
Diana K. Dangoor
Hadley Walsh
Edoardo Marcora
Marco M. Hefti
Alicia Casella
Cheick T. Sissoko
Manav Kapoor
Gloriia Novikova
Evan Udine
Garrett Wong
Weijing Tang
Tushar Bhangale
Julie Hunkapiller
Gai Ayalon
Robert R. Graham
Jonathan D. Cherry
Etty P. Cortes
Valeriy Y. Borukov
Ann C. McKee
Thor D. Stein
Jean-Paul Vonsattel
Andy F. Teich
Marla Gearing
Jonathan Glass
Juan C. Troncoso
Matthew P. Frosch
Bradley T. Hyman
Dennis W. Dickson
Melissa E. Murray
Johannes Attems
Margaret E. Flanagan
Qinwen Mao
M.-Marsel Mesulam
Sandra Weintraub
Randy L. Woltjer
Thao Pham
Julia Kofler
Julie A. Schneider
Lei Yu
Dushyant P. Purohit
Vahram Haroutunian
Patrick R. Hof
Sam Gandy
Mary Sano
Thomas G. Beach
Wayne Poon
Claudia H. Kawas
María M. Corrada
Robert A. Rissman
Jeff Metcalf
Sara Shuldberg
Bahar Salehi
Peter T. Nelson
John Q. Trojanowski
Edward B. Lee
David A. Wolk
Corey T. McMillan
C. Dirk Keene
Caitlin S. Latimer
Thomas J. Montine
Gabor G. Kovacs
Mirjam I. Lutz
Peter Fischer
Richard J. Perrin
Nigel J. Cairns
Erin E. Franklin
Herbert T. Cohen
Towfique Raj
Inma Cobos
Bess Frost
Alison Goate
Charles L. White III
John F. Crary
Affiliated Authors:
Jean-Paul Vonsattel
Andy F. Teich
Columbia Affiliation:
Subjects:
Homeodomain Proteins (MeSH)
Tauopathies (MeSH)
Tumor Suppressor Proteins (MeSH)
Grants:
R01CA079830 (NIH – National Cancer Institute)
UL1TR001414 (NIH – National Center for Advancing Translational Sciences)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS095252 (NIH – National Institute of Neurological Disorders and Stroke)
U24NS072026 (NIH – National Institute of Neurological Disorders and Stroke)
K23NS109284 (NIH – National Institute of Neurological Disorders and Stroke)
U54NS115266 (NIH – National Institute of Neurological Disorders and Stroke)
P30NS055077 (NIH – National Institute of Neurological Disorders and Stroke)
P50AG005138 (NIH – National Institute On Aging)
P30AG010124 (NIH – National Institute On Aging)
K99AG070109 (NIH – National Institute On Aging)
P50AG016573 (NIH – National Institute On Aging)
P30AG066444 (NIH – National Institute On Aging)
P30AG010161 (NIH – National Institute On Aging)
R01AG062348 (NIH – National Institute On Aging)
P50AG025688 (NIH – National Institute On Aging)
P30AG066514 (NIH – National Institute On Aging)
P30AG013854 (NIH – National Institute On Aging)
F32AG056098 (NIH – National Institute On Aging)
P01AG026276 (NIH – National Institute On Aging)
K08AG065463 (NIH – National Institute On Aging)
P30AG072946 (NIH – National Institute On Aging)
U01AG006781 (NIH – National Institute On Aging)
R01AG054449 (NIH – National Institute On Aging)
P01AG000538 (NIH – National Institute On Aging)
U01AG058635 (NIH – National Institute On Aging)
RF1AG060961 (NIH – National Institute On Aging)
R01AG066152 (NIH – National Institute On Aging)
P50AG005136 (NIH – National Institute On Aging)
U24AG021886 (NIH – National Institute On Aging)
P30AG008017 (NIH – National Institute On Aging)
P30AG066509 (NIH – National Institute On Aging)
P50AG005134 (NIH – National Institute On Aging)
P01AG017586 (NIH – National Institute On Aging)
P30AG066462 (NIH – National Institute On Aging)
P30AG072979 (NIH – National Institute On Aging)
P50AG005681 (NIH – National Institute On Aging)
U19AG062418 (NIH – National Institute On Aging)
P01AG003991 (NIH – National Institute On Aging)
P50AG008702 (NIH – National Institute On Aging)
P30AG066511 (NIH – National Institute On Aging)
P30AG072977 (NIH – National Institute On Aging)
P30AG066507 (NIH – National Institute On Aging)
P50AG005131 (NIH – National Institute On Aging)
P50AG005146 (NIH – National Institute On Aging)
R01AG059848 (NIH – National Institute On Aging)
P30AG062429 (NIH – National Institute On Aging)
P30AG062421 (NIH – National Institute On Aging)
P30AG066468 (NIH – National Institute On Aging)
R01AG021055 (NIH – National Institute On Aging)
P30AG028383 (NIH – National Institute On Aging)
P30AG072980 (NIH – National Institute On Aging)
P30AG066519 (NIH – National Institute On Aging)
P01AG066597 (NIH – National Institute On Aging)
P30AG019610 (NIH – National Institute On Aging)
R01AG054008 (NIH – National Institute On Aging)
S10OD030463 (NIH – Office of the Director, National Institutes of Health)
S10OD026880 (NIH – Office of the Director, National Institutes of Health)
Publication Type:
Article
Unique ID:
10.1007/s00401-021-02379-z
PMID:
34719765
DOI:
10.1007/s00401-021-02379-z
Journal:
Acta Neuropathologica
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record
View Web of Science Record

Record Created:

Features of “ET plus” correlate with age and tremor duration: “ET plus” may be a disease stage rather than a subtype of essential tremor

Louis, E. D., Huey, E. D., & Cosentino, S. (2021). Features of “ET plus” correlate with age and tremor duration: “ET plus” may be a disease stage rather than a subtype of essential tremor. Parkinsonism & Related Disorders, 91, 42–47. https://doi.org/10.1016/j.parkreldis.2021.08.017
Authors:
Elan D. Louis
Edward D. Huey
Stephanie Cosentino
Affiliated Authors:
Edward D. Huey
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Age Factors (MeSH)
Disease Progression (MeSH)
Essential Tremor (MeSH)
Symptom Assessment (MeSH)
Author Keywords:
essential tremor
classification
et plus
clinical
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1016/j.parkreldis.2021.08.017
PMID:
34482193
DOI:
10.1016/j.parkreldis.2021.08.017
Journal:
Parkinsonism and Related Disorders
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record
View Web of Science Record

Record Created:

Mild cognitive impairment, dementia and risk of mortality in essential tremor: A longitudinal prospective study of elders

Delgado, N., Hernandez, D. I., Radler, K., Huey, E. D., Cosentino, S., & Louis, E. (2021). Mild cognitive impairment, dementia and risk of mortality in essential tremor: A longitudinal prospective study of elders. Journal of the Neurological Sciences, 428, 117563. https://doi.org/10.1016/j.jns.2021.117563
Authors:
Nikki Delgado
Daniella Iglesias Hernandez
Keith Radler
Edward D. Huey
Stephanie Cosentino
Elan Louis
Affiliated Authors:
Edward D. Huey
Stephanie Cosentino
Columbia Affiliation:
Subjects:
Cognitive Dysfunction (MeSH)
Dementia (MeSH)
Essential Tremor (MeSH)
Author Keywords:
essential tremor
mortality
dementia
cognitive aging
epidemiology
longitudinal
Grants:
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS117745 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS088257 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1016/j.jns.2021.117563
PMID:
34274879
DOI:
10.1016/j.jns.2021.117563
Journal:
Journal of the Neurological Sciences
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record
View Web of Science Record

Record Created:

Dentate Nucleus Neuronal Density: A Postmortem Study of Essential Tremor Versus Control Brains

Hartstone, W. G., Brown, M. H., Kelly, G. C., Tate, W. J., Kuo, S., Dwork, A. J., Louis, E. D., & Faust, P. L. (2020). Dentate Nucleus Neuronal Density: A Postmortem Study of Essential Tremor Versus Control Brains. Movement Disorders, 36(4), 995–999. Portico. https://doi.org/10.1002/mds.28402
Authors:
Whitney G. Hartstone
Mark H. Brown
Geoffrey C. Kelly
William J. Tate
Sheng-Han Kuo
Andrew J. Dwork
Elan D. Louis
Phyllis L. Faust
Affiliated Authors:
Whitney G. Hartstone
Mark H. Brown
Geoffrey C. Kelly
William J. Tate
Sheng-Han Kuo
Andrew J. Dwork
Phyllis L. Faust
Columbia Affiliation:
Subjects:
Essential Tremor (MeSH)
Author Keywords:
essential tremor; cerebellum; dentate neuron; stereology; pathology
essential tremor
cerebellum
dentate neuron
stereology
pathology
Grants:
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
R56MH117769 (NIH – National Institute of Mental Health)
R01NS073872 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS086736 (NIH – National Institute of Neurological Disorders and Stroke)
R03NS114871 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS094607 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS104423 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS085136 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS088257 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS118179 (NIH – National Institute of Neurological Disorders and Stroke)
R01AG066162 (NIH – National Institute On Aging)
I01BX002876 (NIH – Veterans Affairs)
I01BX003794 (NIH – Veterans Affairs)
Publication Type:
Article
Unique ID:
10.1002/mds.28402
PMID:
33258511
DOI:
10.1002/mds.28402
Journal:
Movement Disorders
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record

Record Created:

CSV