Calcium

Displaying 1 - 30 of 30CSV
Horne, C. R., Dite, T. A., Young, S. N., Mather, L. J., Dagley, L. F., Johnson, J. L., Yaron-Barir, T. M., Huntsman, E. M., Daly, L. A., Byrne, D. P., Cadell, A. L., Ng, B. H., Yousef, J., Multari, D. H., Shen, L., McAloon, L. M., Manning, G., Febbraio, M. A., Means, A. R., … Murphy, J. M. (2025). PSKH1 kinase activity is differentially modulated via allosteric binding of Ca 2+ sensor proteins. Proceedings of the National Academy of Sciences, 122(8). https://doi.org/10.1073/pnas.2420961122
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Cefis, M., Marcangeli, V., Hammad, R., Granet, J., Leduc-Gaudet, J.-P., Gaudreau, P., Trumpff, C., Huang, Q., Picard, M., Aubertin-Leheudre, M., Bélanger, M., Robitaille, R., Morais, J. A., & Gouspillou, G. (2025). Impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in men. Cell Reports Medicine, 6(2), 101968. https://doi.org/10.1016/j.xcrm.2025.101968
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Miotto, M. C., Reiken, S., Wronska, A., Yuan, Q., Dridi, H., Liu, Y., Weninger, G., Tchagou, C., & Marks, A. R. (2024). Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-51791-y
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Krukenberg, S., Möckl, F., Weiß, M., Dekiert, P., Hofmann, M., Gerlach, F., Winterberg, K. J., Kovacevic, D., Khansahib, I., Troost, B., Hinrichs, M., Granato, V., Nawrocki, M., Hub, T., Tsvilovskyy, V., Medert, R., Woelk, L.-M., Förster, F., Li, H., … Guse, A. H. (2024). MASTER-NAADP: a membrane permeable precursor of the Ca2+ mobilizing second messenger NAADP. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52024-y
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Weninger, G., Miotto, M. C., Tchagou, C., Reiken, S., Dridi, H., Brandenburg, S., Riedemann, G. C., Yuan, Q., Liu, Y., Chang, A., Wronska, A., Lehnart, S. E., & Marks, A. R. (2024). Structural insights into the regulation of RyR1 by S100A1. Proceedings of the National Academy of Sciences, 121(27). https://doi.org/10.1073/pnas.2400497121
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Miller, R. J. H., Killekar, A., Shanbhag, A., Bednarski, B., Michalowska, A. M., Ruddy, T. D., Einstein, A. J., Newby, D. E., Lemley, M., Pieszko, K., Van Kriekinge, S. D., Kavanagh, P. B., Liang, J. X., Huang, C., Dey, D., Berman, D. S., & Slomka, P. J. (2024). Predicting mortality from AI cardiac volumes mass and coronary calcium on chest computed tomography. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-46977-3
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Dwarkanath, P., Muhihi, A., Sudfeld, C. R., Wylie, B. J., Wang, M., Perumal, N., Thomas, T., Kinyogoli, S. M., Bakari, M., Fernandez, R., Raj, J.-M., Swai, N. O., Buggi, N., Shobha, R., Sando, M. M., Duggan, C. P., Masanja, H. M., Kurpad, A. V., Pembe, A. B., & Fawzi, W. W. (2024). Two Randomized Trials of Low-Dose Calcium Supplementation in Pregnancy. New England Journal of Medicine, 390(2), 143–153. https://doi.org/10.1056/nejmoa2307212
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Rubin, M. R., Cusano, N., Yin, S., Tokareva, E., Ayodele, O., & Finkelman, R. D. (2024). Extended Treatment With Recombinant Human Parathyroid Hormone (1-84) in Adult Patients With Chronic Hypoparathyroidism. Endocrine Practice, 30(3), 200–208. https://doi.org/10.1016/j.eprac.2023.12.001
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Sleiman, Y., Reiken, S., Charrabi, A., Jaffré, F., Sittenfeld, L. R., Pasquié, J.-L., Colombani, S., Lerman, B. B., Chen, S., Marks, A. R., Cheung, J. W., Evans, T., Lacampagne, A., & Meli, A. C. (2023). Personalized medicine in the dish to prevent calcium leak associated with short-coupled polymorphic ventricular tachycardia in patient-derived cardiomyocytes. Stem Cell Research & Therapy, 14(1). https://doi.org/10.1186/s13287-023-03502-5
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Dridi, H., Santulli, G., Bahlouli, L., Miotto, M. C., Weninger, G., & Marks, A. R. (2023). Mitochondrial Calcium Overload Plays a Causal Role in Oxidative Stress in the Failing Heart. Biomolecules, 13(9), 1409. https://doi.org/10.3390/biom13091409
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Neuberger, A., Trofimov, Y. A., Yelshanskaya, M. V., Khau, J., Nadezhdin, K. D., Khosrof, L. S., Krylov, N. A., Efremov, R. G., & Sobolevsky, A. I. (2023). Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-40362-2
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del Rivero Morfin, P. J., Marx, S. O., & Ben-Johny, M. (2023). Sympathetic Nervous System Regulation of Cardiac Calcium Channels. Voltage-Gated Ca2+ Channels: Pharmacology, Modulation and Their Role in Human Disease, 59–82. https://doi.org/10.1007/164_2022_632
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Martuscello, R. T., Chen, M.-L., Reiken, S., Sittenfeld, L. R., Ruff, D. S., Ni, C.-L., Lin, C.-C., Pan, M.-K., Louis, E. D., Marks, A. R., Kuo, S.-H., & Faust, P. L. (2023). Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium ‘leak’ in tremor pathophysiology. Acta Neuropathologica, 146(2), 301–318. https://doi.org/10.1007/s00401-023-02602-z
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Evans, S. W., Shi, D.-Q., Chavarha, M., Plitt, M. H., Taxidis, J., Madruga, B., Fan, J. L., Hwang, F.-J., van Keulen, S. C., Suomivuori, C.-M., Pang, M. M., Su, S., Lee, S., Hao, Y. A., Zhang, G., Jiang, D., Pradhan, L., Roth, R. H., Liu, Y., … Lin, M. Z. (2023). A positively tuned voltage indicator for extended electrical recordings in the brain. Nature Methods, 20(7), 1104–1113. https://doi.org/10.1038/s41592-023-01913-z
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Agarwal, S., McMahon, D. J., Chen, J., Brossfield, A. V., Fernando, J., Bilezikian, J. P., Cusano, N. E., & Rubin, M. R. (2020). The Clinical and Skeletal Effects of Long-Term Therapy of Hypoparathyroidism With rhPTH(1-84). Journal of Bone and Mineral Research, 38(4), 480–492. https://doi.org/10.1002/jbmr.4780
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Chen, J., Zhang, I. L., Terry, M. B., & Yang, W. (2022). Dietary Factors and Early-Onset Colorectal Cancer in the United States—an Ecologic Analysis. Cancer Epidemiology, Biomarkers & Prevention, 32(2), 217–225. https://doi.org/10.1158/1055-9965.epi-22-0442
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Heffron, R., Muwonge, T. R., Boyer, J., Matovu, F., Zia, Y., Bagaya, M., Ssebuliba, T., Morrison, S., Bambia, F., Nsubuga, R., Badaru, J., Stein, G., Mugwanya, K. K., Wyatt, C., Baeten, J. M., Yin, M. T., Mujugira, A., Thomas, K., … Anderson, P. (2022). Bone mineral density, nutrient intake, and physical activity among young women from Uganda. Archives of Osteoporosis, 17(1). https://doi.org/10.1007/s11657-022-01155-0
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Weninger, G., Pochechueva, T., El Chami, D., Luo, X., Kohl, T., Brandenburg, S., Urlaub, H., Guan, K., Lenz, C., & Lehnart, S. E. (2022). Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-14320-9
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Khan, A. A., Guyatt, G., Ali, D. S., Bilezikian, J. P., Collins, M. T., Dandurand, K., Mannstadt, M., Murphy, D., M’Hiri, I., Rubin, M. R., Sanders, R., Shrayyef, M., Siggelkow, H., Tabacco, G., Tay, Y.-K. D., Van Uum, S., Vokes, T., Winer, K. K., Yao, L., & Rejnmark, L. (2020). Management of Hypoparathyroidism. Journal of Bone and Mineral Research, 37(12), 2663–2677. https://doi.org/10.1002/jbmr.4716
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Perez-Zoghbi, J. F., Sajorda, D. R., Webb, D. A., Arnold, L. A., Emala, C. W., & Yocum, G. T. (2022). Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization. American Journal of Respiratory Cell and Molecular Biology, 67(4), 482–490. https://doi.org/10.1165/rcmb.2022-0084oc
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Shen, S., Sewanan, L. R., Shao, S., Halder, S. S., Stankey, P., Li, X., & Campbell, S. G. (2022). Physiological calcium combined with electrical pacing accelerates maturation of human engineered heart tissue. Stem Cell Reports, 17(9), 2037–2049. https://doi.org/10.1016/j.stemcr.2022.07.006
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Melville, Z., Dridi, H., Yuan, Q., Reiken, S., Wronska, A., Liu, Y., Clarke, O. B., & Marks, A. R. (2022). A drug and ATP binding site in type 1 ryanodine receptor. Structure, 30(7), 1025-1034.e4. https://doi.org/10.1016/j.str.2022.04.010
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Miotto, M. C., & Marks, A. R. (2022). Catching the next wave of recombinant RyR2 cryo-EM structures. Commentary on “Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.” Cell Calcium, 105, 102614. https://doi.org/10.1016/j.ceca.2022.102614
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Al Rifai, M., Blaha, M. J., Nambi, V., Shea, S. J. C., Michos, E. D., Blumenthal, R. S., Ballantyne, C. M., Szklo, M., Greenland, P., Miedema, M. D., Nasir, K., Rotter, J. I., Guo, X., Yao, J., Post, W. S., & Virani, S. S. (2022). Determinants of Incident Atherosclerotic Cardiovascular Disease Events Among Those With Absent Coronary Artery Calcium: Multi-Ethnic Study of Atherosclerosis. Circulation, 145(4), 259–267. https://doi.org/10.1161/circulationaha.121.056705
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Park, J., Zuo, H., Frangaj, A., Fu, Z., Yen, L. Y., Zhang, Z., Mosyak, L., Slavkovich, V. N., Liu, J., Ray, K. M., Cao, B., Vallese, F., Geng, Y., Chen, S., Grassucci, R., Dandey, V. P., Tan, Y. Z., Eng, E., Lee, Y., … Fan, Q. R. (2021). Symmetric activation and modulation of the human calcium-sensing receptor. Proceedings of the National Academy of Sciences, 118(51). https://doi.org/10.1073/pnas.2115849118
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Zanou, N., Dridi, H., Reiken, S., Imamura de Lima, T., Donnelly, C., De Marchi, U., Ferrini, M., Vidal, J., Sittenfeld, L., Feige, J. N., Garcia-Roves, P. M., Lopez-Mejia, I. C., Marks, A. R., Auwerx, J., Kayser, B., & Place, N. (2021). Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-27422-1
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