Ryanodine Receptor Calcium Release Channel

Displaying 1 - 7 of 7CSV
Miotto, M. C., Reiken, S., Wronska, A., Yuan, Q., Dridi, H., Liu, Y., Weninger, G., Tchagou, C., & Marks, A. R. (2024). Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-51791-y
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Weninger, G., Miotto, M. C., Tchagou, C., Reiken, S., Dridi, H., Brandenburg, S., Riedemann, G. C., Yuan, Q., Liu, Y., Chang, A., Wronska, A., Lehnart, S. E., & Marks, A. R. (2024). Structural insights into the regulation of RyR1 by S100A1. Proceedings of the National Academy of Sciences, 121(27). https://doi.org/10.1073/pnas.2400497121
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Dridi, H., Liu, Y., Reiken, S., Liu, X., Argyrousi, E. K., Yuan, Q., Miotto, M. C., Sittenfeld, L., Meddar, A., Soni, R. K., Arancio, O., Lacampagne, A., & Marks, A. R. (2023). Heart failure-induced cognitive dysfunction is mediated by intracellular Ca2+ leak through ryanodine receptor type 2. Nature Neuroscience, 26(8), 1365–1378. https://doi.org/10.1038/s41593-023-01377-6
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Martuscello, R. T., Chen, M.-L., Reiken, S., Sittenfeld, L. R., Ruff, D. S., Ni, C.-L., Lin, C.-C., Pan, M.-K., Louis, E. D., Marks, A. R., Kuo, S.-H., & Faust, P. L. (2023). Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium ‘leak’ in tremor pathophysiology. Acta Neuropathologica, 146(2), 301–318. https://doi.org/10.1007/s00401-023-02602-z
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Stutzman, M. J., Kim, C. S. J., Tester, D. J., Hamrick, S. K., Dotzler, S. M., Giudicessi, J. R., Miotto, M. C., GC, J. B., Frank, J., Marks, A. R., & Ackerman, M. J. (2022). Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential. Stem Cell Reports, 17(9), 2023–2036. https://doi.org/10.1016/j.stemcr.2022.07.002
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Melville, Z., Dridi, H., Yuan, Q., Reiken, S., Wronska, A., Liu, Y., Clarke, O. B., & Marks, A. R. (2022). A drug and ATP binding site in type 1 ryanodine receptor. Structure, 30(7), 1025-1034.e4. https://doi.org/10.1016/j.str.2022.04.010
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Miotto, M. C., & Marks, A. R. (2022). Catching the next wave of recombinant RyR2 cryo-EM structures. Commentary on “Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.” Cell Calcium, 105, 102614. https://doi.org/10.1016/j.ceca.2022.102614
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