Liver

Displaying 1 - 12 of 12CSV
Pita-Juarez, Y., Karagkouni, D., Kalavros, N., Melms, J. C., Niezen, S., Delorey, T. M., Essene, A. L., Brook, O. R., Pant, D., Skelton-Badlani, D., Naderi, P., Huang, P., Pan, L., Hether, T., Andrews, T. S., Ziegler, C. G. K., Reeves, J., Myloserdnyy, A., Chen, R., … Vlachos, I. S. (2025). A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Genome Biology, 26(1). https://doi.org/10.1186/s13059-025-03499-5
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Gaspar, R. C., Macêdo, A. P. A., Nakandakari, S. C. B. R., Muñoz, V. R., Abud, G. F., Vieira, R. F. L., de Sousa Neto, I. V., Pavan, I. C. B., da Silva, L. G. S., Simabuco, F. M., da Silva, A. S. R., Junior, W. S., Marchini, J. S., Nonino, C. B., Cintra, D. E., Ropelle, E. R., Pajvani, U. B., de Freitas, E. C., & Pauli, J. R. (2025). Notch1 Signalling Is Downregulated by Aerobic Exercise, Leading to Improvement of Hepatic Metabolism in Obese Mice. Liver International, 45(4). Portico. https://doi.org/10.1111/liv.70068
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Zhu, Y., Cai, S. S., Ma, J., Cheng, L., Wei, C., Aggarwal, A., Toh, W. H., Shin, C., Shen, R., Kong, J., Mao, S. A., Lao, Y.-H., Leong, K. W., & Mao, H.-Q. (2024). Optimization of lipid nanoparticles for gene editing of the liver via intraduodenal delivery. Biomaterials, 308, 122559. https://doi.org/10.1016/j.biomaterials.2024.122559
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Clement, C. C., Osan, J., Buque, A., Nanaware, P. P., Chang, Y.-C., Perino, G., Shetty, M., Yamazaki, T., Tsai, W. L., Urbanska, A. M., Calvo-Calle, J. M., Ramsamooj, S., Ramsamooj, S., Vergani, D., Mieli-Vergani, G., Terziroli Beretta-Piccoli, B., Gadina, M., Montagna, C., Goncalves, M. D., … Santambrogio, L. (2022). PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes. Science Immunology, 7(74). https://doi.org/10.1126/sciimmunol.abl3795
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Ronaldson-Bouchard, K., Teles, D., Yeager, K., Tavakol, D. N., Zhao, Y., Chramiec, A., Tagore, S., Summers, M., Stylianos, S., Tamargo, M., Lee, B. M., Halligan, S. P., Abaci, E. H., Guo, Z., Jacków, J., Pappalardo, A., Shih, J., Soni, R. K., Sonar, S., … Vunjak-Novakovic, G. (2022). A multi-organ chip with matured tissue niches linked by vascular flow. Nature Biomedical Engineering, 6(4), 351–371. https://doi.org/10.1038/s41551-022-00882-6
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Izquierdo, M. C., Shanmugarajah, N., Lee, S. X., Kraakman, M. J., Westerterp, M., Kitamoto, T., Harris, M., Cook, J. R., Gusarova, G. A., Zhong, K., Marbuary, E., O-Sullivan, I., Rasmus, N., Camastra, S., Unterman, T. G., Ferrannini, E., Hurwitz, B. E., & Haeusler, R. A. (2022). Hepatic FoxOs link insulin signaling with plasma lipoprotein metabolism through an apolipoprotein M/sphingosine-1-phosphate pathway. Journal of Clinical Investigation, 132(7). https://doi.org/10.1172/jci146219
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Bhat, N., Esteghamat, F., Chaube, B. K., Gunawardhana, K., Mani, M., Thames, C., Jain, D., Ginsberg, H. N., Fernandes‐Hernando, C., & Mani, A. (2022). TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut‐liver crosstalk. The FASEB Journal, 36(3). Portico. https://doi.org/10.1096/fj.202101607r
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Morales-Arráez, D., Ventura-Cots, M., Altamirano, J., Abraldes, J. G., Cruz-Lemini, M., Thursz, M. R., Atkinson, S. R., Sarin, S. K., Kim, W., Chavez-Araujo, R., Higuera-de la Tijera, M. F., Singal, A. K., Shah, V. H., Kamath, P. S., Duarte-Rojo, A., Charles, E. A., Vargas, V., Jager, M., Rautou, P. E., … Bataller, R. (2021). The MELD Score Is Superior to the Maddrey Discriminant Function Score to Predict Short-Term Mortality in Alcohol-Associated Hepatitis: A Global Study. American Journal of Gastroenterology. https://doi.org/10.14309/ajg.0000000000001596
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Bhat, N., Narayanan, A., Fathzadeh, M., Kahn, M., Zhang, D., Goedeke, L., Neogi, A., Cardone, R. L., Kibbey, R. G., Fernandez-Hernando, C., Ginsberg, H. N., Jain, D., Shulman, G. I., & Mani, A. (2022). Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice. Journal of Clinical Investigation, 132(3). https://doi.org/10.1172/jci153724
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Ferdouse, A., Agrawal, R. R., Gao, M. A., Jiang, H., Blaner, W. S., & Clugston, R. D. (2022). Alcohol induced hepatic retinoid depletion is associated with the induction of multiple retinoid catabolizing cytochrome P450 enzymes. PLOS ONE, 17(1), e0261675. https://doi.org/10.1371/journal.pone.0261675
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Wang, L., Yu, J., Zhou, Q., Wang, X., Mukhanova, M., Du, W., Sun, L., Pajvani, U. B., & Accili, D. (2022). TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver. Cell Metabolism, 34(1), 158-170.e5. https://doi.org/10.1016/j.cmet.2021.11.013
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