Optimization of lipid nanoparticles for gene editing of the liver via intraduodenal delivery

Zhu, Y., Cai, S. S., Ma, J., Cheng, L., Wei, C., Aggarwal, A., Toh, W. H., Shin, C., Shen, R., Kong, J., Mao, S. A., Lao, Y.-H., Leong, K. W., & Mao, H.-Q. (2024). Optimization of lipid nanoparticles for gene editing of the liver via intraduodenal delivery. Biomaterials, 308, 122559. https://doi.org/10.1016/j.biomaterials.2024.122559
Authors:
Yining Zhu
Shuting Sarah Cai
Jingyao Ma
Leonardo Cheng
Christine Wei
Ataes Aggarwal
Wu Han Toh
Charles Shin
Ruochen Shen
Jiayuan Kong
Shuming Alan Mao
Yeh-Hsing Lao
Kam W Leong
Hai-Quan Mao
Affiliated Authors:
Shuting Sarah Cai
Yeh-Hsing Lao
Kam W Leong
Columbia Affiliation:
Subjects:
Gene Editing (MeSH)
Liver (MeSH)
Nanoparticles (MeSH)
Lipids (MeSH)
Author Keywords:
lipid nanoparticles
liver gene editing
plasmid dna
intraduodenal injection
oral delivery
hypercholesterolemia
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Publication Type:
Article
Unique ID:
10.1016/j.biomaterials.2024.122559
PMID:
38583366
DOI:
10.1016/j.biomaterials.2024.122559
Journal:
Biomaterials
Publication Date:
Data Source:
PubMed
Source Link:
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