Organoids

Displaying 1 - 17 of 17CSV
Syphers, J. L., Wright, J. A., Liu, S., Gee, Y. S., Gao, F., Mudududdla, R., Che, D. Q., Chang, A., Sloan, E. K., Narasimhan, V., Heriot, A., Ramsay, R. G., de Nys, R., Silva, T. N., Vrbanac, L., Sammour, T., Lawrence, M. J., Tin, T., Maddern, G. J., … Baell, J. B. (2025). Discovery of WEE1 Kinase Inhibitors with Potent Activity against Patient-Derived, Metastatic Colorectal Cancer Organoids. Journal of Medicinal Chemistry, 68(8), 8065–8090. https://doi.org/10.1021/acs.jmedchem.4c02541
Publication Date
Xu, C., He, S., Zhu, Y., Crasto, G., Chen, C., Clay, M. L., Lao, Y.-H., & Leong, K. W. (2024). Vascular Organoid Generation from Human-Induced Pluripotent Stem Cells. Journal of Visualized Experiments, 214. https://doi.org/10.3791/67125
Publication Date
Buonfiglioli, A., Kübler, R., Missall, R., De Jong, R., Chan, S., Haage, V., Wendt, S., Lin, A. J., Mattei, D., Graziani, M., Latour, B., Gigase, F., Chiu, R., Zhang, Y., Nygaard, H. B., De Jager, P. L., & De Witte, L. D. (2025). A microglia-containing cerebral organoid model to study early life immune challenges. Brain, Behavior, and Immunity, 123, 1127–1146. https://doi.org/10.1016/j.bbi.2024.11.008
Publication Date
Su, S. H., Mitani, Y., Li, T., Sachdeva, U., Flashner, S., Klein-Szanto, A., Dunbar, K. J., Abrams, J., Nakagawa, H., & Gabre, J. (2024). Lactate Suppresses Growth of Esophageal Adenocarcinoma Patient-Derived Organoids through Alterations in Tumor NADH/NAD+ Redox State. Biomolecules, 14(9), 1195. https://doi.org/10.3390/biom14091195
Publication Date
Shimonosono, M., Morimoto, M., Hirose, W., Tomita, Y., Matsuura, N., Flashner, S., Ebadi, M. S., Okayasu, E. H., Lee, C. Y., Britton, W. R., Martin, C., Wuertz, B. R., Parikh, A. S., Sachdeva, U. M., Ondrey, F. G., Atigadda, V. R., Elmets, C. A., Abrams, J. A., Muir, A. B., … Nakagawa, H. (2024). Modeling Epithelial Homeostasis and Perturbation in Three-Dimensional Human Esophageal Organoids. Biomolecules, 14(9), 1126. https://doi.org/10.3390/biom14091126
Publication Date
Ross, A. B., Gorhe, D., Kim, J. K., Hodapp, S., DeVine, L., Chan, K. M., Chio, I. I. C., Jovanovic, M., & Ayres Pereira, M. (2024). Systematic analysis of proteome turnover in an organoid model of pancreatic cancer by dSILO. Cell Reports Methods, 4(5), 100760. https://doi.org/10.1016/j.crmeth.2024.100760
Publication Date
Kim, H. S., Xiao, Y., Chen, X., He, S., Im, J., Willner, M. J., Finlayson, M. O., Xu, C., Zhu, H., Choi, S. J., Mosharov, E. V., Kim, H., Xu, B., & Leong, K. W. (2024). Chronic Opioid Treatment Arrests Neurodevelopment and Alters Synaptic Activity in Human Midbrain Organoids. Advanced Science, 11(21). Portico. https://doi.org/10.1002/advs.202400847
Publication Date
Buckley, K. H., Beyries, K. A., Ryeom, S., Yoon, S. S., & Katona, B. W. (2024). Establishment and Characterization of Patient-derived Gastric Organoids from Biopsies of Benign Gastric Body and Antral Epithelium. Journal of Visualized Experiments, 203. https://doi.org/10.3791/66094
Publication Date
Santos, A. K., Scalzo, S., de Souza, R. T. V., Santana, P. H. G., Marques, B. L., Oliveira, L. F., Filho, D. M., Kihara, A. H., da Costa Santiago, H., Parreira, R. C., Birbrair, A., Ulrich, H., & Resende, R. R. (2023). Strategic use of organoids and organs-on-chip as biomimetic tools. Seminars in Cell & Developmental Biology, 144, 3–10. https://doi.org/10.1016/j.semcdb.2022.09.010
Publication Date
de Oliveira, L. F., Filho, D. M., Marques, B. L., Maciel, G. F., Parreira, R. C., do Carmo Neto, J. R., Da Silva, P. E. F., Guerra, R. O., da Silva, M. V., Santiago, H. da C., Birbrair, A., Kihara, A. H., Dias da Silva, V. J., Glaser, T., Resende, R. R., & Ulrich, H. (2023). Organoids as a novel tool in modelling infectious diseases. Seminars in Cell & Developmental Biology, 144, 87–96. https://doi.org/10.1016/j.semcdb.2022.09.003
Publication Date

Duan, X., Wang, H., Ho, D. D., Schwartz, R. E., Evans, T., & Chen, S. (2021). Comments on ‘An airway organoid-based screen identifies a role for the HIF1α‒glycolysis axis in SARS-CoV-2 infection.’ Journal of Molecular Cell Biology, 14(1). https://doi.org/10.1093/jmcb/mjab075

Publication Date
Gil, V., Miranda, S., Riisnaes, R., Gurel, B., D’Ambrosio, M., Vasciaveo, A., Crespo, M., Ferreira, A., Brina, D., Troiani, M., Sharp, A., Sheehan, B., Christova, R., Seed, G., Figueiredo, I., Lambros, M., Dolling, D., Rekowski, J., Alajati, A., … de Bono, J. (2021). HER3 Is an Actionable Target in Advanced Prostate Cancer. Cancer Research, 81(24), 6207–6218. https://doi.org/10.1158/0008-5472.can-21-3360
Publication Date
de Jong, J. O., Llapashtica, C., Genestine, M., Strauss, K., Provenzano, F., Sun, Y., Zhu, H., Cortese, G. P., Brundu, F., Brigatti, K. W., Corneo, B., Migliori, B., Tomer, R., Kushner, S. A., Kellendonk, C., Javitch, J. A., Xu, B., & Markx, S. (2021). Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24358-4
Publication Date
Karakasheva, T. A., Gabre, J. T., Sachdeva, U. M., Cruz-Acuña, R., Lin, E. W., DeMarshall, M., Falk, G. W., Ginsberg, G. G., Yang, Z., Kim, M. M., Diffenderfer, E. S., Pitarresi, J. R., Li, J., Muir, A. B., Hamilton, K. E., Nakagawa, H., Bass, A. J., & Rustgi, A. K. (2021). Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-00706-8
Publication Date
Duan, X., Tang, X., Nair, M. S., Zhang, T., Qiu, Y., Zhang, W., Wang, P., Huang, Y., Xiang, J., Wang, H., Schwartz, R. E., Ho, D. D., Evans, T., & Chen, S. (2021). An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection. Cell Reports, 37(6), 109920. https://doi.org/10.1016/j.celrep.2021.109920
Publication Date