Cognitive Dysfunction

Displaying 1 - 50 of 136CSV
Springer, M. V., Whitney, R. T., Ye, W., Briceño, E. M., Gross, A. L., Aparicio, H. J., Beiser, A. S., Burke, J. F., Elkind, M. S. V., Ferber, R. A., Giordani, B., Gottesman, R. F., Hayward, R. A., Howard, V. J., Kollipara, A. S., Koton, S., Lazar, R. M., Longstreth, W. T., Pendlebury, S. T., … Levine, D. A. (2025). Education Levels and Poststroke Cognitive Trajectories. JAMA Network Open, 8(3), e252002. https://doi.org/10.1001/jamanetworkopen.2025.2002
Publication Date
Fioriti, L., Wijesekara, N., Argyrousi, E. K., Matsuzaki, S., Takamura, H., Satoh, K., Han, K., Yamauchi, H., Staniszewski, A., Acquarone, E., Orsini, F., Martucci, A., Katayama, T., Arancio, O., & Fraser, P. E. (2025). Genetic and pharmacologic enhancement of SUMO2 conjugation prevents and reverses cognitive impairment and synaptotoxicity in a preclinical model of Alzheimer’s disease. Alzheimer’s & Dementia, 21(3). Portico. https://doi.org/10.1002/alz.70030
Publication Date
Katsumi, Y., Touroutoglou, A., Brickhouse, M., Eloyan, A., Eckbo, R., Zaitsev, A., La Joie, R., Lagarde, J., Schonhaut, D., Thangarajah, M., Taurone, A., Vemuri, P., Jack, C. R., Dage, J. L., Nudelman, K. N. H., Foroud, T., Hammers, D. B., Ghetti, B., … Murray, M. E. (2025). Dissociable spatial topography of cortical atrophy in early‐onset and late‐onset Alzheimer’s disease: A head‐to‐head comparison of the LEADS and ADNI cohorts. Alzheimer’s & Dementia, 21(2). Portico. https://doi.org/10.1002/alz.14489
Publication Date
Siemers, E., Feaster, T., Sethuraman, G., Sundell, K., Skljarevski, V., Cline, E. N., Zhang, H., Jerecic, J., Honig, L. S., Salloway, S., Sperling, R., Trame, M. N., Dodds, M. G., & Johnson, K. (2025). INTERCEPT-AD, a phase 1 study of intravenous sabirnetug in participants with mild cognitive impairment or mild dementia due to Alzheimer’s disease. The Journal of Prevention of Alzheimer’s Disease, 12(1), 100005. https://doi.org/10.1016/j.tjpad.2024.100005
Publication Date
Zolnoori, M., Zolnour, A., Vergez, S., Sridharan, S., Spens, I., Topaz, M., Noble, J. M., Bakken, S., Hirschberg, J., Bowles, K., Onorato, N., & McDonald, M. V. (2024). Beyond electronic health record data: leveraging natural language processing and machine learning to uncover cognitive insights from patient-nurse verbal communications. Journal of the American Medical Informatics Association. https://doi.org/10.1093/jamia/ocae300
Publication Date
Kever, A., Heuer, L. B., Simani, L., & Leavitt, V. M. (2024). Development and initial validation of the Cognitive Change Scale (CCS). Multiple Sclerosis Journal, 30(14), 1815–1824. https://doi.org/10.1177/13524585241290102
Publication Date
Lin, Y., & Kuo, S.-H. (2024). The emerging role of the cerebellum in neurodegeneration linked to cognitive impairment. Journal of Alzheimer’s Disease, 102(1), 30–32. https://doi.org/10.1177/13872877241283678
Publication Date
Gonzales, L., Saperstein, A. M., Qian, M., Gorecki, A., & Medalia, A. (2024). Psychiatric and functional correlates of stigma associated with cognitive impairment in schizophrenia. Psychiatry Research, 342, 116233. https://doi.org/10.1016/j.psychres.2024.116233
Publication Date
Lo, J. W., Crawford, J. D., Lipnicki, D. M., Lipton, R. B., Katz, M. J., Preux, P.-M., Guerchet, M., d’Orsi, E., Quialheiro, A., Rech, C. R., Ritchie, K., Skoog, I., Najar, J., Sterner, T. R., Rolandi, E., Davin, A., Rossi, M., Riedel-Heller, S. G., Pabst, A., … Sachdev, P. S. (2024). Trajectory of Cognitive Decline Before and After Stroke in 14 Population Cohorts. JAMA Network Open, 7(10), e2437133. https://doi.org/10.1001/jamanetworkopen.2024.37133
Publication Date
Lu, L., Zhang, Y., Angley, M., Bejerano, S., Brockman, J. D., McClure, L. A., Unverzagt, F. W., Fly, A. D., & Kahe, K. (2024). Association of Urinary Cadmium Concentration With Cognitive Impairment in US Adults. Neurology, 103(7). https://doi.org/10.1212/wnl.0000000000209808
Publication Date
Qian, M., Motter, J., Deehan, E., Graff, J., Adhikari, A., Doraiswamy, P. M., Goldberg, T. E., & Devanand, D. P. (2024). Predictors of Improvement after Cognitive Training in Mild Cognitive Impairment: Insights from the Cognitive Training and Neuroplasticity in Mild Cognitive Impairment Trial. Alzheimer Disease & Associated Disorders, 38(3), 227–234. https://doi.org/10.1097/wad.0000000000000639
Publication Date
Cole, K. L., Boehme, A. K., Thacker, E. L., Longstreth Jr., W. T., Brown, B. L., Gale, S. D., Hedges, D. W., Anderson, J. K., & Elkind, M. S. V. (2023). Hospital-Acquired Infection at Time of Stroke and Cognitive Decline: The Cardiovascular Health Study. Cerebrovascular Diseases, 53(4), 382–390. Portico. https://doi.org/10.1159/000533568
Publication Date
Tucker, A., Goldberg, T. E., & Kim, H. (2024). Biomarkers of sleep-wake disturbance as predictors of cognitive decline and accelerated disease progression. Expert Review of Molecular Diagnostics, 24(8), 649–657. https://doi.org/10.1080/14737159.2024.2389307
Publication Date
Simani, L., Molaeipour, L., Kian, S., & Leavitt, V. M. (2024). Correlation between cognitive changes and neuroradiological changes over time in multiple sclerosis: a systematic review and meta-analysis. Journal of Neurology, 271(8), 5498–5518. https://doi.org/10.1007/s00415-024-12517-8
Publication Date
Nichols, E., Gross, A. L., Zhang, Y. S., Meijer, E., Hayat, S., Steptoe, A., Langa, K. M., & Lee, J. (2024). Considerations for the use of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) in cross‐country comparisons of cognitive aging and dementia. Alzheimer’s & Dementia, 20(7), 4635–4648. Portico. https://doi.org/10.1002/alz.13895
Publication Date
Zhang, A., Wengler, K., Zhu, X., Horga, G., Goldberg, T. E., & Lee, S. (2024). Altered Hierarchical Gradients of Intrinsic Neural Timescales in Mild Cognitive Impairment and Alzheimer’s Disease. The Journal of Neuroscience, 44(25), e2024232024. https://doi.org/10.1523/jneurosci.2024-23.2024
Publication Date
Denham, M. W., Arnold, M. L., Sanchez, V. A., Lin, F. R., Tucker, L. H., Gomez, M. C., Fernandez, K., Arpi, P., Neil, H., Boyle, S., Selevan, S., Sussman, T. J., Gmelin, T., Fine, I., Glynn, N. W., Teresi, J., Noble, J. M., Goldberg, T., Luchsinger, J. A., & Golub, J. S. (2024). Design and Methods of the Early Age-Related Hearing Loss Investigation Randomized Controlled Trial. Otology & Neurotology, 45(5), 594–601. https://doi.org/10.1097/mao.0000000000004093
Publication Date
Kerner, N., Goldberg, T. E., Cohen, H. R., Phillips, J. G., Cohen, D. E., Andrews, H., Pelton, G., & Devanand, D. P. (2024). Sleep–wake behavior, perceived fatigability, and cognitive reserve in older adults. Alzheimer’s & Dementia, 20(6), 4020–4031. Portico. https://doi.org/10.1002/alz.13802
Publication Date
Wisch, J. K., McKay, N. S., Boerwinkle, A. H., Kennedy, J., Flores, S., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Rafii, M. S., O’Bryant, S. E., Price, J. C., Laymon, C. M., Krinsky-McHale, S. J., Lai, F., Rosas, H. D., Hartley, S. L., Zaman, S., Lott, I. T., … Mori, H. (2024). Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer’s disease: a cross-sectional study. The Lancet Neurology, 23(5), 500–510. https://doi.org/10.1016/s1474-4422(24)00084-x
Publication Date
Ghanem, A., Berry, D. S., Burkes, A., Grill, N., Hall, T. M., Hart, K. A., Hernandez, N. C., Chapman, S., Sharma, V. D., Huey, E. D., Cosentino, S. A., & Louis, E. D. (2024). Prevalence of and Annual Conversion Rates to Mild Cognitive Impairment and Dementia: Prospective, Longitudinal Study of an Essential Tremor Cohort. Annals of Neurology, 95(6), 1193–1204. Portico. https://doi.org/10.1002/ana.26927
Publication Date
Edwin, T. H., Håberg, A. K., Zotcheva, E., Bratsberg, B., Jugessur, A., Engdahl, B., Bowen, C., Selbæk, G., Kohler, H.-P., Harris, J. R., Tom, S. E., Krokstad, S., Mekonnen, T., Stern, Y., Skirbekk, V. F., & Strand, B. H. (2024). Trajectories of Occupational Cognitive Demands and Risk of Mild Cognitive Impairment and Dementia in Later Life. Neurology, 102(9). https://doi.org/10.1212/wnl.0000000000209353
Publication Date
Buchman, A. S., Yu, L., Klein, H.-U., Zammit, A. R., Oveisgharan, S., Nag, S., Tickotsky, N., Levy, H., Seyfried, N., Morgenstern, D., Levin, Y., Schnaider Beeri, M., & Bennett, D. A. (2024). Glycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults. Neurology, 102(7). https://doi.org/10.1212/wnl.0000000000209223
Publication Date
Yang, Y. C., Walsh, C. E., Shartle, K., Stebbins, R. C., Aiello, A. E., Belsky, D. W., Harris, K. M., Chanti-Ketterl, M., & Plassman, B. L. (2023). An Early and Unequal Decline: Life Course Trajectories of Cognitive Aging in the United States. Journal of Aging and Health, 36(3–4), 230–245. https://doi.org/10.1177/08982643231184593
Publication Date
GOYAL, P., DIDOMENICO, R. J., PRESSLER, S. J., IBEH, C., WHITE-WILLIAMS, C., ALLEN, L. A., GORODESKI, E. Z., Albert, N., Fudim, M., Lekavich, C., Watson, K., Gulati, S., Kalogeropoulos, A., & Lewsey, S. (2024). Cognitive Impairment in Heart Failure: A Heart Failure Society of America Scientific Statement. Journal of Cardiac Failure, 30(3), 488–504. https://doi.org/10.1016/j.cardfail.2024.01.003
Publication Date
Tsapanou, A., Ghanem, A., Chapman, S., Stern, Y., Huey, E. D., Cosentino, S., & Louis, E. D. (2024). Sleep problems as predictors of cognitive decline in essential tremor: A prospective longitudinal cohort study. Sleep Medicine, 116, 13–18. https://doi.org/10.1016/j.sleep.2024.02.016
Publication Date
Poole, V. N., Ridwan, A. R., Arfanakis, K., Dawe, R. J., Seyfried, N. T., De Jager, P. L., Schneider, J. A., Leurgans, S. E., Yu, L., & Bennett, D. A. (2024). Associations of brain morphology with cortical proteins of cognitive resilience. Neurobiology of Aging, 137, 1–7. https://doi.org/10.1016/j.neurobiolaging.2024.02.005
Publication Date
Morales, C. D., Cotton-Samuel, D., Lao, P. J., Chang, J. F., Pyne, J. D., Alshikho, M. J., Lippert, R. V., Bista, K., Hale, C., Edwards, N. C., Igwe, K. C., Deters, K., Zimmerman, M. E., & Brickman, A. M. (2024). Small vessel cerebrovascular disease is associated with cognition in prospective Alzheimer’s clinical trial participants. Alzheimer’s Research & Therapy, 16(1). https://doi.org/10.1186/s13195-024-01395-x
Publication Date
Rossano, S. M., Johnson, A. S., Smith, A., Ziaggi, G., Roetman, A., Guzman, D., Okafor, A., Klein, J., Tomljanovic, Z., Stern, Y., Brickman, A. M., Lee, S., Kreisl, W. C., & Lao, P. (2024). Microglia measured by TSPO PET are associated with Alzheimer’s disease pathology and mediate key steps in a disease progression model. Alzheimer’s & Dementia, 20(4), 2397–2407. Portico. https://doi.org/10.1002/alz.13699
Publication Date
Barbera, M., Lehtisalo, J., Perera, D., Aspö, M., Cross, M., De Jager Loots, C. A., Falaschetti, E., Friel, N., Luchsinger, J. A., Gavelin, H. M., Peltonen, M., Price, G., Neely, A. S., Thunborg, C., Tuomilehto, J., Mangialasche, F., Middleton, L., Ngandu, T., … Solomon, A. (2024). A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability: the MET-FINGER randomised controlled trial protocol. Alzheimer’s Research & Therapy, 16(1). https://doi.org/10.1186/s13195-023-01355-x
Publication Date
Whitman, E. T., Ryan, C. P., Abraham, W. C., Addae, A., Corcoran, D. L., Elliott, M. L., Hogan, S., Ireland, D., Keenan, R., Knodt, A. R., Melzer, T. R., Poulton, R., Ramrakha, S., Sugden, K., Williams, B. S., Zhou, J., Hariri, A. R., Belsky, D. W., Moffitt, T. E., & Caspi, A. (2024). A blood biomarker of the pace of aging is associated with brain structure: replication across three cohorts. Neurobiology of Aging, 136, 23–33. https://doi.org/10.1016/j.neurobiolaging.2024.01.008
Publication Date
Vyas, C. M., Manson, J. E., Sesso, H. D., Cook, N. R., Rist, P. M., Weinberg, A., Moorthy, M. V., Baker, L. D., Espeland, M. A., Yeung, L.-K., Brickman, A. M., & Okereke, O. I. (2024). Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS. The American Journal of Clinical Nutrition, 119(3), 692–701. https://doi.org/10.1016/j.ajcnut.2023.12.011
Publication Date
Gu, Y., Honig, L. S., Kang, M. S., Bahl, A., Sanchez, D., Reyes‐Dumeyer, D., Manly, J. J., Dage, J. L., Lantigua, R. A., Brickman, A. M., Vardarajan, B. N., & Mayeux, R. (2024). Risk of Alzheimer’s disease is associated with longitudinal changes in plasma biomarkers in the multi‐ethnic Washington Heights–Hamilton Heights–Inwood Columbia Aging Project (WHICAP) cohort. Alzheimer’s & Dementia, 20(3), 1988–1999. Portico. https://doi.org/10.1002/alz.13652
Publication Date
Hojjati, S. H., Chiang, G. C., Butler, T. A., de Leon, M., Gupta, A., Li, Y., Sabuncu, M. R., Feiz, F., Nayak, S., Shteingart, J., Ozoria, S., Gholipour Picha, S., Stern, Y., Luchsinger, J. A., Devanand, D. P., & Razlighi, Q. R. (2024). Remote Associations Between Tau and Cortical Amyloid-β Are Stage-Dependent. Journal of Alzheimer’s Disease, 98(4), 1467–1482. https://doi.org/10.3233/jad-231362
Publication Date
Jones, R. N., Manly, J. J., Langa, K. M., Ryan, L. H., Levine, D. A., McCammon, R., & Weir, D. (2023). Factor structure of the Harmonized Cognitive Assessment Protocol neuropsychological battery in the Health and Retirement Study. Journal of the International Neuropsychological Society, 30(1), 47–55. https://doi.org/10.1017/s135561772300019x
Publication Date
Katayama, O., Stern, Y., Habeck, C., Lee, S., Harada, K., Makino, K., Tomida, K., Morikawa, M., Yamaguchi, R., Nishijima, C., Misu, Y., Fujii, K., Kodama, T., & Shimada, H. (2023). Neurophysiological markers in community-dwelling older adults with mild cognitive impairment: an EEG study. Alzheimer’s Research & Therapy, 15(1). https://doi.org/10.1186/s13195-023-01368-6
Publication Date
Mishkin, A. D., Prince, E. J., Leimbach, E. J., Mapara, M. Y., & Carroll, C. P. (2023). Psychiatric comorbidities in adults with sickle cell disease: A narrative review. British Journal of Haematology, 203(5), 747–759. Portico. https://doi.org/10.1111/bjh.18981
Publication Date
Javitt, D. C., Martinez, A., Sehatpour, P., Beloborodova, A., Habeck, C., Gazes, Y., Bermudez, D., Razlighi, Q. R., Devanand, D. P., & Stern, Y. (2023). Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment. Alzheimer’s Research & Therapy, 15(1). https://doi.org/10.1186/s13195-023-01189-7
Publication Date
Mehta, N. H., Zhou, L., Li, Y., McIntire, L. B., Nordvig, A., Butler, T., de Leon, M., & Chiang, G. C. (2023). Peripheral immune cell imbalance is associated with cortical beta-amyloid deposition and longitudinal cognitive decline. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-34012-2
Publication Date
Membreno, R., Thomas, K. R., Calcetas, A. T., Edwards, L., Bordyug, M., Showell, M., Stanfill, M., Brenner, E. K., Walker, K. S., Rotblatt, L. J., Brickman, A. M., Edmonds, E. C., & Bangen, K. J. (2023). Regional White Matter Hyperintensities Relate to Specific Cognitive Abilities in Older Adults Without Dementia. Alzheimer Disease & Associated Disorders, 37(4), 303–309. https://doi.org/10.1097/wad.0000000000000585
Publication Date
Gadde, K. M., Yin, X., Goldberg, R. B., Orchard, T. J., Schlögl, M., Dabelea, D., Ibebuogu, U. N., Watson, K. E., Pi‐Sunyer, F. X., Crandall, J. P., Temprosa, M., & Luchsinger, J. A. (2023). Coronary Artery Calcium and Cognitive Decline in the Diabetes Prevention Program Outcomes Study. Journal of the American Heart Association, 12(21). https://doi.org/10.1161/jaha.123.029671
Publication Date
Azar, M., Chapman, S., Joyce, J., Schultheis, M., Zhang, Z., Waltrip, L., Shagalow, S., Zeiger, P., Sunderaraman, P., & Cosentino, S. (2023). Education as a Moderator of Help Seeking Behavior in Subjective Cognitive Decline. Alzheimer Disease & Associated Disorders, 37(3), 184–188. https://doi.org/10.1097/wad.0000000000000571
Publication Date
Ramirez, M., Teresi, J. A., Ellis, J., Gonzalez-Lopez, P., Silver, S., Rutigliano, M., Vidal-Manzano, J., Boratgis, G., Devanand, D. P., van Meer, I., Bhatti, I., Bhatti, U., & Luchsinger, J. A. (2023). Unexpected lucidity in dementia: application of qualitative methods to develop an informant-reported lucidity measure. Aging & Mental Health, 27(12), 2395–2402. https://doi.org/10.1080/13607863.2023.2207167
Publication Date
Eloyan, A., Thangarajah, M., An, N., Borowski, B. J., Reddy, A. L., Aisen, P., Dage, J. L., Foroud, T., Ghetti, B., Griffin, P., Hammers, D., Iaccarino, L., Jack, C. R., Kirby, K., Kramer, J., Koeppe, R., Kukull, W. A., La Joie, R., … Mundada, N. S. (2023). White matter hyperintensities are higher among early‐onset Alzheimer’s disease participants than their cognitively normal and early‐onset nonAD peers: Longitudinal Early‐onset Alzheimer’s Disease Study (LEADS). Alzheimer’s & Dementia, 19(S9). Portico. https://doi.org/10.1002/alz.13402
Publication Date
Shaaban, C. E., Rosano, C., Zhu, X., Rutherford, B. R., Witonsky, K. R., Rosso, A. L., Yaffe, K., & Brown, P. J. (2023). Discordant Biological and Chronological Age: Implications for Cognitive Decline and Frailty. The Journals of Gerontology: Series A, 78(11), 2152–2161. https://doi.org/10.1093/gerona/glad174
Publication Date
Sun, Y., Moghekar, A., Soldan, A., Pettigrew, C., Greenberg, B., Albert, M., & Wang, M.-C. (2023). Cerebrospinal Fluid Alzheimer’s Disease Biomarker Patterns of Change Prior to the Onset of Mild Cognitive Impairment. Journal of Alzheimer’s Disease, 96(1), 287–300. https://doi.org/10.3233/jad-230807
Publication Date
Gorijala, P., Aslam, M. M., Dang, L. T., Xicota, L., Fernandez, M. V., Sung, Y. J., Fan, K., Feingold, E., Surace, E. I., Chhatwal, J. P., Hom, C. L., Hartley, S. L., Hassenstab, J., Perrin, R. J., Mapstone, M., Zaman, S. H., Ances, B. M., Kamboh, M. I., … Lee, J. H. (2023). Alzheimer’s polygenic risk scores are associated with cognitive phenotypes in Down syndrome. Alzheimer’s & Dementia, 20(2), 1038–1049. Portico. https://doi.org/10.1002/alz.13506
Publication Date
Frontera, J. A., Guekht, A., Allegri, R. F., Ashraf, M., Baykan, B., Crivelli, L., Easton, A., Garcia-Azorin, D., Helbok, R., Joshi, J., Koehn, J., Koralnik, I., Netravathi, M., Michael, B., Nilo, A., Özge, A., Padda, K., Pellitteri, G., Prasad, K., … Winkler, A. S. (2023). Evaluation and treatment approaches for neurological post-acute sequelae of COVID-19: A consensus statement and scoping review from the global COVID-19 neuro research coalition. Journal of the Neurological Sciences, 454, 120827. https://doi.org/10.1016/j.jns.2023.120827
Publication Date
Zhang, Y., Shen, Y., Liufu, N., Liu, L., Li, W., Shi, Z., Zheng, H., Mei, X., Chen, C.-Y., Jiang, Z., Abtahi, S., Dong, Y., Liang, F., Shi, Y., Cheng, L. L., Yang, G., Kang, J. X., Wilkinson, J. E., & Xie, Z. (2023). Transmission of Alzheimer’s disease-associated microbiota dysbiosis and its impact on cognitive function: evidence from mice and patients. Molecular Psychiatry, 28(10), 4421–4437. https://doi.org/10.1038/s41380-023-02216-7
Publication Date