Epidemiology and Management of NAFLD

Displaying 1 - 48 of 48CSV
Pita-Juarez, Y., Karagkouni, D., Kalavros, N., Melms, J. C., Niezen, S., Delorey, T. M., Essene, A. L., Brook, O. R., Pant, D., Skelton-Badlani, D., Naderi, P., Huang, P., Pan, L., Hether, T., Andrews, T. S., Ziegler, C. G. K., Reeves, J., Myloserdnyy, A., Chen, R., … Vlachos, I. S. (2025). A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Genome Biology, 26(1). https://doi.org/10.1186/s13059-025-03499-5
Publication Date
Rosenthal, B. E., Hoteit, M. A., Lluri, G., Haeffele, C., Daugherty, T., Krasuski, R. A., Serfas, J. D., de Freitas, R. A., Porlier, A., Lubert, A. M., Wu, F. M., Valente, A. M., Krieger, E. V., Buber, Y., Rodriguez, F. H., Gaignard, S., Saraf, A., Hindes, M., Earing, M. G., … Kim, Y. Y. (2025). Characteristics and Survival Outcomes of Hepatocellular Carcinoma After the Fontan Operation. JACC: Advances, 4(4), 101646. https://doi.org/10.1016/j.jacadv.2025.101646
Publication Date
Vujasinovic, M., Ebrahimi, F., Roelstraete, B., Bergman, D., Sun, J., Sadr‐Azodi, O., Löhr, J. ‐Matthias, & Ludvigsson, J. F. (2025). Metabolic Dysfunction‐Associated Steatotic Liver Disease and Pancreatic Disease—A Population‐Based Nationwide Cohort and Sibling‐Controlled Study. United European Gastroenterology Journal. Portico. https://doi.org/10.1002/ueg2.12761
Publication Date
Mallhi, A. K., Kiely, K., Roy, V., Ovchinsky, N., Woo Baidal, J. A., Rochani, H., & Zhang, J. (2025). The change of alanine aminotransferase distributions among US youths, NHANES 1988–2020. Journal of Pediatric Gastroenterology and Nutrition. Portico. https://doi.org/10.1002/jpn3.12460
Publication Date
Basile, A. O., Verma, A., Tang, L. A., Serper, M., Scanga, A., Farrell, A., Destin, B., Carr, R. M., Anyanwu‐Ofili, A., Rajagopal, G., Krikhely, A., Bessler, M., Reilly, M. P., Ritchie, M. D., Tatonetti, N. P., & Wattacheril, J. (2024). Rapid identification and phenotyping of nonalcoholic fatty liver disease patients using a machine‐based approach in diverse healthcare systems. Clinical and Translational Science, 18(1). Portico. https://doi.org/10.1111/cts.70105
Publication Date
Agarwal, H., Wang, Y., Tinsley, B., Wang, X., & Ozcan, L. (2025). RAP1A suppresses hepatic steatosis by regulating amino acid-mediated mTORC1 activation. JHEP Reports, 7(4), 101303. https://doi.org/10.1016/j.jhepr.2024.101303
Publication Date
Reis, S. P., Haider, S., Brejt, S., Ahmad, N., & Sperling, D. (2024). Transjugular Intrahepatic Portosystemic Shunt (TIPS) Check and Revision in a Freestanding Outpatient Facility: Safety and Efficacy. Cureus. https://doi.org/10.7759/cureus.74517
Publication Date
Geng, J., Ruan, X., Wu, X., Chen, X., Fu, T., Gill, D., Burgess, S., Chen, J., Ludvigsson, J. F., Larsson, S. C., Li, X., Du, Z., & Yuan, S. (2024). Network Mendelian randomisation analysis deciphers protein pathways linking type 2 diabetes and gastrointestinal disease. Diabetes, Obesity and Metabolism. Portico. https://doi.org/10.1111/dom.16087
Publication Date
Chen, J., Dan, L., Yuan, S., Fu, T., Sun, J., Wolk, A., Ludvigsson, J. F., Li, X., Wang, X., & Larsson, S. C. (2024). Dietary Antioxidant Capacity, Genetic Susceptibility and Polymorphism, and Inflammatory Bowel Disease Risk in a Prospective Cohort. Clinical Gastroenterology and Hepatology. https://doi.org/10.1016/j.cgh.2024.09.033
Publication Date
Al-Karaghouli, M., Ventura-Cots, M., Wong, Y. J., Genesca, J., Bosques, F., Brown, R. S., Mathurin, P., Louvet, A., Shawcross, D., Vargas, V., Verna, E. C., Schnabl, B., Caballeria, J., Shah, V. J., Kamath, P. S., Lucey, M. R., Garcia-Tsao, G., Bataller, R., & Abraldes, J. G. (2024). Relationship between updated MELD and prognosis in alcohol-associated hepatitis: Opportunities for more efficient trial design. Hepatology Communications, 8(8). https://doi.org/10.1097/hc9.0000000000000495
Publication Date
Tarchi, S. M., Salvatore, M., Lichtenstein, P., Sekar, T., Capaccione, K., Luk, L., Shaish, H., Makkar, J., Desperito, E., Leb, J., Navot, B., Goldstein, J., Laifer, S., Beylergil, V., Ma, H., Jambawalikar, S., Aberle, D., D’Souza, B., Bentley-Hibbert, S., & Marin, M. P. (2024). Radiology of fibrosis part II: abdominal organs. Journal of Translational Medicine, 22(1). https://doi.org/10.1186/s12967-024-05346-w
Publication Date
Te, H. S., Lee, D. H., Woolley, A. E., Abidi, M. Z., Fisher, C., Sellers, M. T., Taimur, S., Livelli, T., Watkins, T., Handarova, D., Berry, G. J., Graves, R., Ho, C., Hughart, A. L., Kittleson, M., Marboe, C. C., Miller, R. A., Sharma, T. S., Trindade, A. J., … Danziger‐Isakov, L. (2024). Hepatitis B transmission/reactivation associated with Hepatitis B core antibody and Hepatitis C nucleic acid testing positive organs: A report from the Organ Procurement and Transplantation Network Disease Transmission Advisory Committee. Transplant Infectious Disease. Portico. https://doi.org/10.1111/tid.14305
Publication Date
Ghooray, D. T., Xu, M., Shi, H., McClain, C. J., & Song, M. (2024). Hepatocyte-Specific Fads1 Overexpression Attenuates Western Diet-Induced Metabolic Phenotypes in a Rat Model. International Journal of Molecular Sciences, 25(9), 4836. https://doi.org/10.3390/ijms25094836
Publication Date
Petta, S., Targher, G., Romeo, S., Pajvani, U. B., Zheng, M., Aghemo, A., & Valenti, L. V. C. (2024). The first MASH drug therapy on the horizon: Current perspectives of resmetirom. Liver International, 44(7), 1526–1536. Portico. https://doi.org/10.1111/liv.15930
Publication Date
Li, X., Bhattacharya, D., Yuan, Y., Wei, C., Zhong, F., Ding, F., D’Agati, V. D., Lee, K., Friedman, S. L., & He, J. C. (2024). Chronic kidney disease in a murine model of non-alcoholic steatohepatitis (NASH). Kidney International, 105(3), 540–561. https://doi.org/10.1016/j.kint.2023.12.009
Publication Date
Aleyadeh, W., Verna, E. C., Elbeshbeshy, H., Sulkowski, M. S., Smith, C., Darling, J., Sterling, R. K., Muir, A., Akushevich, L., La, D., Terrault, N., Fried, M. W., & Feld, J. J. (2024). Outcomes of early vs late treatment initiation in solid organ transplantation from hepatitis C virus nucleic acid test-positive donors to hepatitis C virus-uninfected recipients: Results from the HCV-TARGET study. American Journal of Transplantation, 24(3), 468–478. https://doi.org/10.1016/j.ajt.2023.10.006
Publication Date
Reuter, M. A., Tucker, M., Marfori, Z., Shishani, R., Bustamante, J. M., Moreno, R., Goodson, M. L., Ehrlich, A., Taha, A. Y., Lein, P. J., Joshi, N., Brito, I., Durbin-Johnson, B., Nandakumar, R., & Cummings, B. P. (2024). Dietary resistant starch supplementation increases gut luminal deoxycholic acid abundance in mice. Gut Microbes, 16(1). https://doi.org/10.1080/19490976.2024.2315632
Publication Date
Huang, P., Ran, J., Zhu, W., Dai, W., Tang, Y., Lian, P., Huang, X., & Li, R. (2024). PCSK9 dysregulates cholesterol homeostasis and triglyceride metabolism in olanzapine‐induced hepatic steatosis via both receptor‐dependent and receptor‐independent pathways. The FASEB Journal, 38(4). Portico. https://doi.org/10.1096/fj.202301748r
Publication Date
Almeida, F. C., Patra, K., Giannisis, A., Niesnerova, A., Nandakumar, R., Ellis, E., Oliveira, T. G., & Nielsen, H. M. (2024). APOE genotype dictates lipidomic signatures in primary human hepatocytes. Journal of Lipid Research, 65(2), 100498. https://doi.org/10.1016/j.jlr.2024.100498
Publication Date
Phipps, M. M., Choi, A. J., & Brown Jr, R. S. (2024). Narrative review of management of cirrhosis during the treatment of hepatocellular carcinoma. Annals of Palliative Medicine, 13(1), 141–149. https://doi.org/10.21037/apm-23-173
Publication Date
Patra, K., Almeida, F., Giannisis, A., Niesnerova, A., Nandakumar, R., Ellis, E., Oliveira, T. G., & Nielsen, H. M. (2023). APOE genotype‐specific lipidomic signatures in primary human hepatocytes. Alzheimer’s & Dementia, 19(S13). Portico. https://doi.org/10.1002/alz.076471
Publication Date
Senatus, L., Egaña-Gorroño, L., López-Díez, R., Bergaya, S., Aranda, J. F., Amengual, J., Arivazhagan, L., Manigrasso, M. B., Yepuri, G., Nimma, R., Mangar, K. N., Bernadin, R., Zhou, B., Gugger, P. F., Li, H., Friedman, R. A., Theise, N. D., Shekhtman, A., Fisher, E. A., … Schmidt, A. M. (2023). DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice. Communications Biology, 6(1). https://doi.org/10.1038/s42003-023-04643-2
Publication Date
Wang, X., Moore, M. P., Shi, H., Miyata, Y., Donnelly, S. K., Radiloff, D. R., & Tabas, I. (2023). Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers. Molecular Therapy - Methods & Clinical Development, 31, 101165. https://doi.org/10.1016/j.omtm.2023.101165
Publication Date
Park, D. K., Chen, M., Kim, S., Joo, Y. Y., Loving, R. K., Kim, H. S., Cha, J., Yoo, S., & Kim, J. H. (2023). Overestimated prediction using polygenic prediction derived from summary statistics. BMC Genomic Data, 24(1). https://doi.org/10.1186/s12863-023-01151-4
Publication Date
Untalan, M., Crimmins, N. A., Mencin, A., Yates, K., Stavra, X., & Thaker, V. (2023). FRI591 Association Of TSH Levels And NAFLD Severity In Children And Adolescents. Journal of the Endocrine Society, 7(Supplement_1). https://doi.org/10.1210/jendso/bvad114.1498
Publication Date
Nobel, Y. R., Park, H., Koerner, A., Tillman, A. M., Seeram, D., Moallem, D. H., Annavajhala, M. K., Gomez-Simmonds, A., Verna, E. C., & Uhlemann, A.-C. (2023). S1499 Gut Microbiota as a Biomarker of Hepatocellular Carcinoma in Patients With Cirrhosis. American Journal of Gastroenterology, 118(10S), S1136–S1137. https://doi.org/10.14309/01.ajg.0000955636.85132.22
Publication Date
Hagström, H., Thiele, M., Sharma, R., Simon, T. G., Roelstraete, B., Söderling, J., Sundström, J., & Ludvigsson, J. F. (2023). Cardiovascular Outcomes in Patients With Biopsy-proven Alcohol-related Liver Disease. Clinical Gastroenterology and Hepatology, 21(7), 1841-1853.e12. https://doi.org/10.1016/j.cgh.2022.10.022
Publication Date
Sharma, R., Schluger, A., Ahmed, F. S., Nobel, Y. R., Guo, X., Zhao, B., & Verna, E. C. (2023). Visceral adiposity in cirrhosis: Association with disease severity and impact of liver transplantation. Hepatology Communications, 7(6). https://doi.org/10.1097/hc9.0000000000000113
Publication Date
Moore, M. P., Wang, X., Shi, H., Meroni, M., Cherubini, A., Ronzoni, L., Parks, E. J., Ibdah, J. A., Rector, R. S., Valenti, L., Dongiovanni, P., & Tabas, I. (2023). Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH. JHEP Reports, 5(5), 100716. https://doi.org/10.1016/j.jhepr.2023.100716
Publication Date
Kang, J., Postigo-Fernandez, J., Kim, K., Zhu, C., Yu, J., Meroni, M., Mayfield, B., Bartolomé, A., Dapito, D. H., Ferrante, A. W., Dongiovanni, P., Valenti, L., Creusot, R. J., & Pajvani, U. B. (2023). Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis. JCI Insight, 8(3). https://doi.org/10.1172/jci.insight.165369
Publication Date
Sharma, R., Simon, T. G., Stephansson, O., Verna, E. C., Emond, J., Söderling, J., Roelstraete, B., Hagström, H., & Ludvigsson, J. F. (2023). Pregnancy Outcomes in Women With Autoimmune Hepatitis – A Nationwide Population-based Cohort Study With Histopathology. Clinical Gastroenterology and Hepatology, 21(1), 103-114.e10. https://doi.org/10.1016/j.cgh.2021.12.024
Publication Date
Shi, H., Prough, R. A., McClain, C. J., & Song, M. (2023). Different Types of Dietary Fat and Fructose Interactions Result in Distinct Metabolic Phenotypes in Male Mice. The Journal of Nutritional Biochemistry, 111, 109189. https://doi.org/10.1016/j.jnutbio.2022.109189
Publication Date
Gulla, A., Strupas, K., Chun, M., Wanglong, Q., & Su, G. (2023). Heat Shock Protein 90: Target Molecular Regulator in Acute Pancreatitis and Pancreatic Ductal Adenocarcinoma. HPB, 25, S440. https://doi.org/10.1016/j.hpb.2023.07.515
Publication Date
Tasic, L., Avramović, N., Jadranin, M., Quintero, M., Stanisic, D., Martins, L. G., Costa, T. B. B. C., Novak, E., Odone, V., Rivas, M., Aguiar, T., Carraro, D. M., Werneck da Cunha, I., Lima da Costa, C. M., Maschietto, M., & Krepischi, A. (2022). High-Resolution Magic-Angle-Spinning NMR in Revealing Hepatoblastoma Hallmarks. Biomedicines, 10(12), 3091. https://doi.org/10.3390/biomedicines10123091
Publication Date
Barman, P. M., Patel, Y. A., Xie, J., Zhang, M., Jo, J., Sinha, J., Answine, A., Schluger, A., Walter, K., Biggins, S. W., Cullaro, G., Wong, R., Lai, J. C., VanWagner, L. B., Magee, J., Verna, E. C., & Sharma, P. (2022). Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium. Transplantation Direct, 8(12), e1408. https://doi.org/10.1097/txd.0000000000001408
Publication Date
Zhu, W., Ding, C., Huang, P., Ran, J., Lian, P., Tang, Y., Dai, W., & Huang, X. (2022). Metformin Ameliorates Hepatic Steatosis induced by olanzapine through inhibiting LXRα/PCSK9 pathway. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-09610-1
Publication Date
Richter, L. R., Albert, B. I., Zhang, L., Ostropolets, A., Zitsman, J. L., Fennoy, I., Albers, D. J., & Hripcsak, G. (2022). Data assimilation on mechanistic models of glucose metabolism predicts glycemic states in adolescents following bariatric surgery. Frontiers in Physiology, 13. https://doi.org/10.3389/fphys.2022.923704
Publication Date
Zhang, C., Tremblay, D., Magnotti, J., Ronner, L., Podoltsev, N. A., Gotlib, J., Heaney, M. L., Kuykendall, A., O’Connell, C. L., Fleischman, A. G., Mesa, R., Yacoub, A., Mascarenhas, J., & Shammo, J. M. (2022). Exploratory Predictors for Hydroxyurea Treatment Duration in Polycythemia Vera: A Retrospective Multi-Institutional Database Analysis. Blood, 140(Supplement 1), 9693–9695. https://doi.org/10.1182/blood-2022-157873
Publication Date
Kim, J. Y., Wang, L. Q., Sladky, V. C., Oh, T. G., Liu, J., Trinh, K., Eichin, F., Downes, M., Hosseini, M., Jacotot, E. D., Evans, R. M., Villunger, A., & Karin, M. (2022). PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis. Cell Metabolism, 34(10), 1548-1560.e6. https://doi.org/10.1016/j.cmet.2022.08.005
Publication Date
Choudhury, A., Ratna, A., Lim, A., Sebastian, R. M., Moore, C. L., Filliol, A. A., Bledsoe, J., Dai, C., Schwabe, R. F., Shoulders, M. D., & Mandrekar, P. (2022). Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis. Hepatology Communications, 6(10), 2781–2797. https://doi.org/10.1002/hep4.2058
Publication Date
Columbia Affiliation
Dienstag, A., Dienstag, P., Mohan, K., Mirza, O., Schubert, E., Ford, L., Edelman, M., Im, G., & Shenoy, A. (2022). An Assessment of the Psychosocial Evaluation for Early Liver Transplantation in Patients With Acute Alcoholic Hepatitis in the Context of Alcohol Use Disorder, a Case-Control Study. Substance Abuse: Research and Treatment, 16. https://doi.org/10.1177/11782218221115659
Publication Date
Jiménez, C., Ventura‐Cots, M., Sala, M., Calafat, M., Garcia‐Retortillo, M., Cirera, I., Cañete, N., Soriano, G., Poca, M., Simón‐Talero, M., Altamirano, J., Lucey, M., Garcia‐Tsao, G., Brown, R. S., Schwabe, R. F., Verna, E. C., Schnabl, B., Bosques‐Padilla, F., Mathurin, P., … Vargas, V. (2022). Effect of rifaximin on infections, acute‐on‐chronic liver failure and mortality in alcoholic hepatitis: A pilot study (RIFA‐AH). Liver International, 42(5), 1109–1120. Portico. https://doi.org/10.1111/liv.15207
Publication Date
Hagström, H., Thiele, M., Simon, T. G., Sharma, R., Röckert Tjernberg, A., Roelstraete, B., Söderling, J., & Ludvigsson, J. F. (2022). Risk of infections and their role on subsequent mortality in biopsy‐proven alcohol‐related liver disease. United European Gastroenterology Journal, 10(2), 198–211. Portico. https://doi.org/10.1002/ueg2.12200
Publication Date
Kirk, L. M., Waits, C. M. K., Bashore, A. C., Dosso, B., Meyers, A. K., Renaldo, A. C., DePalma, T. J., Simms, K. N., Hauser, N., Chuang Key, C.-C., McCall, C. E., Parks, J. S., Sergeant, S., Langefeld, C. D., Skardal, A., & Rahbar, E. (2022). Exploiting three-dimensional human hepatic constructs to investigate the impact of rs174537 on fatty acid metabolism. PLOS ONE, 17(1), e0262173. https://doi.org/10.1371/journal.pone.0262173
Publication Date