Cell Chemical Biology

Displaying 1 - 12 of 12
Bennett, J. M., Narwal, S. K., Kabeche, S., Abegg, D., Thathy, V., Hackett, F., Yeo, T., Li, V. L., Muir, R., Faucher, F., Lovell, S., Blackman, M. J., Adibekian, A., Yeh, E., Fidock, D. A., & Bogyo, M. (2024). Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets. Cell Chemical Biology, 31(9), 1714-1728.e10. https://doi.org/10.1016/j.chembiol.2024.07.006
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Lawong, A., Gahalawat, S., Ray, S., Ho, N., Han, Y., Ward, K. E., Deng, X., Chen, Z., Kumar, A., Xing, C., Hosangadi, V., Fairhurst, K. J., Tashiro, K., Liszczak, G., Shackleford, D. M., Katneni, K., Chen, G., Saunders, J., Crighton, E., … Phillips, M. A. (2024). Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria. Cell Chemical Biology, 31(8), 1503-1517.e19. https://doi.org/10.1016/j.chembiol.2024.07.001
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Elleman, A. V., Milicic, N., Williams, D. J., Simko, J., Liu, C. J., Haynes, A. L., Ehrlich, D. E., Makinson, C. D., & Du Bois, J. (2024). Behavioral control through the direct, focal silencing of neuronal activity. Cell Chemical Biology, 31(7), 1324-1335.e20. https://doi.org/10.1016/j.chembiol.2024.04.003
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Stokes, M. E., Vasciaveo, A., Small, J. C., Zask, A., Reznik, E., Smith, N., Wang, Q., Daniels, J., Forouhar, F., Rajbhandari, P., Califano, A., & Stockwell, B. R. (2024). Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers. Cell Chemical Biology, 31(4), 805-819.e9. https://doi.org/10.1016/j.chembiol.2023.11.007
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Mann, J., Reznik, E., Santer, M., Fongheiser, M. A., Smith, N., Hirschhorn, T., Zandkarimi, F., Soni, R. K., Dafré, A. L., Miranda-Vizuete, A., Farina, M., & Stockwell, B. R. (2024). Ferroptosis inhibition by oleic acid mitigates iron-overload-induced injury. Cell Chemical Biology, 31(2), 249-264.e7. https://doi.org/10.1016/j.chembiol.2023.10.012
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Deni, I., Stokes, B. H., Ward, K. E., Fairhurst, K. J., Pasaje, C. F. A., Yeo, T., Akbar, S., Park, H., Muir, R., Bick, D. S., Zhan, W., Zhang, H., Liu, Y. J., Ng, C. L., Kirkman, L. A., Almaliti, J., Gould, A. E., Duffey, M., O’Donoghue, A. J., … Fidock, D. A. (2023). Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell Chemical Biology, 30(5), 470-485.e6. https://doi.org/10.1016/j.chembiol.2023.03.002
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Murithi, J. M., Deni, I., Pasaje, C. F. A., Okombo, J., Bridgford, J. L., Gnädig, N. F., Edwards, R. L., Yeo, T., Mok, S., Burkhard, A. Y., Coburn-Flynn, O., Istvan, E. S., Sakata-Kato, T., Gomez-Lorenzo, M. G., Cowell, A. N., Wicht, K. J., Le Manach, C., Kalantarov, G. F., Dey, S., … Fidock, D. A. (2022). The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance. Cell Chemical Biology, 29(5), 824-839.e6. https://doi.org/10.1016/j.chembiol.2021.06.006
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Summers, R. L., Pasaje, C. F. A., Pisco, J. P., Striepen, J., Luth, M. R., Kumpornsin, K., Carpenter, E. F., Munro, J. T., Lin, D., Plater, A., Punekar, A. S., Shepherd, A. M., Shepherd, S. M., Vanaerschot, M., Murithi, J. M., Rubiano, K., Akidil, A., Ottilie, S., Mittal, N., … Lukens, A. K. (2022). Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention. Cell Chemical Biology, 29(2), 191-201.e8. https://doi.org/10.1016/j.chembiol.2021.07.010
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