CUIMC Publications

Alzheimer's-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury

Record Created:

Friday, July 26, 2024 - 09:33

Agrawal, R. R., Larrea, D., Xu, Y., Shi, L., Zirpoli, H., Cummins, L. G., Emmanuele, V., Song, D., Yun, T. D., Macaluso, F. P., Min, W., Kernie, S. G., Deckelbaum, R. J., & Area-Gomez, E. (2022). Alzheimer’s-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury. Cellular and Molecular Neurobiology, 43(5), 2219–2241. https://doi.org/10.1007/s10571-022-01299-0

Authors:

Rishi R Agrawal

Delfina Larrea

Yimeng Xu

Lingyan Shi

Hylde Zirpoli

Leslie G Cummins

Valentina Emmanuele

Donghui Song

Taekyung D Yun

Frank P Macaluso

Wei Min

Steven G Kernie

Richard J Deckelbaum

Estela Area-Gomez

Affiliated Authors:

Rishi R Agrawal

Delfina Larrea

Yimeng Xu

Hylde Zirpoli

Valentina Emmanuele

Taekyung D Yun

Wei Min

Steven G Kernie

Richard J Deckelbaum

Estela Area-Gomez

Columbia Affiliation:

Subjects:

Mitochondrial Dynamics and Reactive Oxygen Species Regulation (OpenAlex Topic)

Mechanisms of Alzheimer's Disease (OpenAlex Topic)

Endoplasmic Reticulum Stress and Unfolded Protein Response (OpenAlex Topic)

Alzheimer Disease (MeSH)

Brain Injuries, Traumatic (MeSH)

Author Keywords:

brain injury

neurodegeneration

alzheimer's

contact sites

mitochondria

lipids

alzheimer’s

Grants:

P30CA013330 (NIH – National Cancer Institute)

R01EB029523 (NIH – National Institute of Biomedical Imaging and Bioengineering)

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

R13ES027302 (NIH – National Institute of Environmental Health Sciences)

R21NS125395 (NIH – National Institute of Neurological Disorders and Stroke)

R01NS088197 (NIH – National Institute of Neurological Disorders and Stroke)

R01NS095803 (NIH – National Institute of Neurological Disorders and Stroke)

R01AG056387 (NIH – National Institute On Aging)

S10OD016214 (NIH – Office of the Director, National Institutes of Health)

Publication Type:

Article

Unique ID:

10.1007/s10571-022-01299-0

PMID:

36571634

DOI:

10.1007/s10571-022-01299-0

Journal:

Cellular and Molecular Neurobiology

Publication Date:

2023-07-01

Data Source:

PubMed

Source Link:

View OpenAlex Record

Hepatic FoxOs link insulin signaling with plasma lipoprotein metabolism through an apolipoprotein M/sphingosine-1-phosphate pathway

Record Created:

Friday, August 9, 2024 - 14:08

Izquierdo, M. C., Shanmugarajah, N., Lee, S. X., Kraakman, M. J., Westerterp, M., Kitamoto, T., Harris, M., Cook, J. R., Gusarova, G. A., Zhong, K., Marbuary, E., O-Sullivan, I., Rasmus, N., Camastra, S., Unterman, T. G., Ferrannini, E., Hurwitz, B. E., & Haeusler, R. A. (2022). Hepatic FoxOs link insulin signaling with plasma lipoprotein metabolism through an apolipoprotein M/sphingosine-1-phosphate pathway. Journal of Clinical Investigation, 132(7). https://doi.org/10.1172/jci146219

Authors:

María Concepción Izquierdo

Niroshan Shanmugarajah

Samuel X. Lee

Michael J. Kraakman

Marit Westerterp

Takumi Kitamoto

Michael Harris

Joshua R. Cook

Galina A. Gusarova

Kendra Zhong

Elijah Marbuary

InSug O-Sullivan

Nikolaus Rasmus

Stefania Camastra

Terry G. Unterman

Ele Ferrannini

Barry E. Hurwitz

Rebecca A. Haeusler

Affiliated Authors:

María Concepción Izquierdo

Niroshan Shanmugarajah

Samuel X. Lee

Michael J. Kraakman

Takumi Kitamoto

Michael Harris

Joshua R. Cook

Galina A. Gusarova

Kendra Zhong

Elijah Marbuary

Nikolaus Rasmus

Rebecca A. Haeusler

Columbia Affiliation:

Subjects:

Apolipoproteins M (MeSH)

Forkhead Transcription Factors (MeSH)

Insulin (MeSH)

Liver (MeSH)

Lysophospholipids (MeSH)

Sphingosine (MeSH)

Author Keywords:

diabetes

insulin signaling

lipoproteins

metabolism

Grants:

UL1TR001873 (NIH – National Center for Advancing Translational Sciences)

R01HL125649 (NIH – National Heart, Lung, and Blood Institute)

R01HL081817 (NIH – National Heart, Lung, and Blood Institute)

P30DK063608 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

R01DK064819 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

R01DK115825 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

Publication Type:

Article

Unique ID:

10.1172/JCI146219

PMID:

35104242

DOI:

10.1172/JCI146219

Journal:

Journal of Clinical Investigation

Publication Date:

2022-04-01

Data Source:

Scopus

Source Link:

Imaging the Actin Cytoskeleton in Live Budding Yeast Cells

Record Created:

Wednesday, February 12, 2025 - 14:09

Sing, C. N., Yang, E. J., Swayne, T. C., Higuchi-Sanabria, R., Tsang, C. A., Boldogh, I. R., & Pon, L. A. (2021). Imaging the Actin Cytoskeleton in Live Budding Yeast Cells. Cytoskeleton, 53–80. https://doi.org/10.1007/978-1-0716-1661-1_3

Authors:

Cierra N Sing

Emily J Yang

Theresa C Swayne

Ryo Higuchi-Sanabria

Catherine A Tsang

Istvan R Boldogh

Liza A Pon

Affiliated Authors:

Cierra N Sing

Emily J Yang

Theresa C Swayne

Catherine A Tsang

Istvan R Boldogh

Liza A Pon

Columbia Affiliation:

Subjects:

Saccharomyces cerevisiae (MeSH)

Author Keywords:

actin

cytoskeleton

deconvolution

fluorescent proteins

live cell imaging

microscopy

ratio imaging

vital staining

yeast

Grants:

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

R00AG065200 (NIH – National Institute On Aging)

K99AG065200 (NIH – National Institute On Aging)

Publication Type:

Article

Unique ID:

10.1007/978-1-0716-1661-1_3

PMID:

34542848

DOI:

10.1007/978-1-0716-1661-1_3

Journal:

Methods in Molecular Biology

Publication Date:

2021-09-21

Data Source:

PubMed

Source Link:

Imaging the Actin Cytoskeleton in Fixed Budding Yeast Cells

Record Created:

Tuesday, June 10, 2025 - 10:42

Sing, C. N., Yang, E. J., Higuchi-Sanabria, R., Pon, L. A., Boldogh, I. R., & Swayne, T. C. (2021). Imaging the Actin Cytoskeleton in Fixed Budding Yeast Cells. Cytoskeleton, 81–100. https://doi.org/10.1007/978-1-0716-1661-1_4

Authors:

Cierra N Sing

Emily J Yang

Ryo Higuchi-Sanabria

Liza A Pon

Istvan R Boldogh

Theresa C Swayne

Affiliated Authors:

Cierra N Sing

Emily J Yang

Liza A Pon

Istvan R Boldogh

Theresa C Swayne

Columbia Affiliation:

Subjects:

Saccharomyces cerevisiae (MeSH)

Author Keywords:

actin

cytoskeleton

fluorescent proteins

microscopy

super-resolution structured illumination microscopy (sr-sim)

vital staining

yeast

Grants:

P30CA013696 (NIH – National Cancer Institute)

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

R35GM122589 (NIH – National Institute of General Medical Sciences)

F31AG055326 (NIH – National Institute On Aging)

R21AG051047 (NIH – National Institute On Aging)

R33AG051047 (NIH – National Institute On Aging)

R00AG065200 (NIH – National Institute On Aging)

K99AG065200 (NIH – National Institute On Aging)

Publication Type:

Article

Unique ID:

10.1007/978-1-0716-1661-1_4

PMID:

34542849

DOI:

10.1007/978-1-0716-1661-1_4

Journal:

Methods in Molecular Biology

Publication Date:

2021-09-21

Data Source:

PubMed

Source Link:

Competing tissue-specific functions for the Tribbles-1 plasma lipid associated locus

Record Created:

Tuesday, June 10, 2025 - 10:42

Hu, K. Y., & Bauer, R. C. (2021). Competing tissue-specific functions for the Tribbles-1 plasma lipid associated locus. Current Opinion in Lipidology, 32(3), 175–182. https://doi.org/10.1097/mol.0000000000000748

Authors:

Krista Y Hu

Robert C Bauer

Affiliated Authors:

Krista Y Hu

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Medicine
  Seymour, Paul, and Gloria Milstein Division of Cardiology

Subjects:

Cardiovascular Diseases (MeSH)

Intracellular Signaling Peptides and Proteins (MeSH)

Lipids (MeSH)

Protein Serine-Threonine Kinases (MeSH)

Grants:

R01HL141745 (NIH – National Heart, Lung, and Blood Institute)

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

Publication Type:

Article

Unique ID:

10.1097/mol.0000000000000748

PMID:

33883444

DOI:

10.1097/mol.0000000000000748

Journal:

Current Opinion in Lipidology

Publication Date:

2021-04-23

Data Source:

PubMed

Source Link:

Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations

Record Created:

Tuesday, July 22, 2025 - 10:41

Trumpff, C., Michelson, J., Lagranha, C. J., Taleon, V., Karan, K. R., Sturm, G., Lindqvist, D., Fernström, J., Moser, D., Kaufman, B. A., & Picard, M. (2021). Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations. Mitochondrion, 59, 225–245. https://doi.org/10.1016/j.mito.2021.04.002

Authors:

Caroline Trumpff

Jeremy Michelson

Claudia J Lagranha

Veronica Taleon

Kalpita R Karan

Gabriel Sturm

Daniel Lindqvist

Johan Fernström

Dirk Moser

Brett A Kaufman

Martin Picard

Affiliated Authors:

Caroline Trumpff

Jeremy Michelson

Veronica Taleon

Kalpita R Karan

Gabriel Sturm

Martin Picard

Columbia Affiliation:

Subjects:

Brain (MeSH)

Cell-Free Nucleic Acids (MeSH)

Mitochondria (MeSH)

Author Keywords:

mitochondria

non-inflammatory effects

psychosocial stress

standard protocol

cell-free dna

mtdna

Grants:

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

R35GM119793 (NIH – National Institute of General Medical Sciences)

T32GM008155 (NIH – National Institute of General Medical Sciences)

R01MH119336 (NIH – National Institute of Mental Health)

Publication Type:

Article

Unique ID:

10.1016/j.mito.2021.04.002

PMID:

33839318

DOI:

10.1016/j.mito.2021.04.002

Journal:

Mitochondrion

Publication Date:

2021-04-12

Data Source:

PubMed

Source Link:

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

Record Created:

Tuesday, July 22, 2025 - 10:40

Fidler, T. P., Xue, C., Yalcinkaya, M., Hardaway, B., Abramowicz, S., Xiao, T., Liu, W., Thomas, D. G., Hajebrahimi, M. A., Pircher, J., Silvestre-Roig, C., Kotini, A. G., Luchsinger, L. L., Wei, Y., Westerterp, M., Snoeck, H.-W., Papapetrou, E. P., Schulz, C., Massberg, S., … Tall, A. R. (2021). The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis. Nature, 592(7853), 296–301. https://doi.org/10.1038/s41586-021-03341-5

Authors:

Trevor P. Fidler

Chenyi Xue

Mustafa Yalcinkaya

Brian Hardaway

Sandra Abramowicz

Tong Xiao

Wenli Liu

David G. Thomas

Mohammad Ali Hajebrahimi

Joachim Pircher

Carlos Silvestre-Roig

Andriana G. Kotini

Larry L. Luchsinger

Ying Wei

Marit Westerterp

Hans-Willem Snoeck

Eirini P. Papapetrou

Christian Schulz

Steffen Massberg

Oliver Soehnlein

Benjamin Ebert

Ross L. Levine

Muredach P. Reilly

Peter Libby

Nan Wang

Alan R. Tall

Affiliated Authors:

Trevor P. Fidler

Chenyi Xue

Mustafa Yalcinkaya

Brian Hardaway

Sandra Abramowicz

Tong Xiao

Wenli Liu

David G. Thomas

Larry L. Luchsinger

Marit Westerterp

Hans-Willem Snoeck

Muredach P. Reilly

Nan Wang

Alan R. Tall

Columbia Affiliation:

Subjects:

Atherosclerosis (MeSH)

Clonal Hematopoiesis (MeSH)

DNA-Binding Proteins (MeSH)

Inflammasomes (MeSH)

Grants:

R01CA225231 (NIH – National Cancer Institute)

P01CA108671 (NIH – National Cancer Institute)

P30CA008748 (NIH – National Cancer Institute)

P30CA013696 (NIH – National Cancer Institute)

TL1TR001875 (NIH – National Center for Advancing Translational Sciences)

S10RR027050 (NIH – National Center for Research Resources)

R01HL137663 (NIH – National Heart, Lung, and Blood Institute)

R01HL137219 (NIH – National Heart, Lung, and Blood Institute)

R01HL118567 (NIH – National Heart, Lung, and Blood Institute)

F32HL151051 (NIH – National Heart, Lung, and Blood Institute)

F30HL137327 (NIH – National Heart, Lung, and Blood Institute)

R01HL134892 (NIH – National Heart, Lung, and Blood Institute)

R01HL080472 (NIH – National Heart, Lung, and Blood Institute)

R01HL155431 (NIH – National Heart, Lung, and Blood Institute)

R01HL148071 (NIH – National Heart, Lung, and Blood Institute)

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

S10OD020056 (NIH – Office of the Director, National Institutes of Health)

Publication Type:

Article

Unique ID:

10.1038/s41586-021-03341-5

PMID:

33731931

DOI:

10.1038/s41586-021-03341-5

Journal:

Nature

Publication Date:

2021-04-08

Data Source:

Scopus

Source Link:

Structure of the Arabidopsis Glutamate Receptor-like Channel GLR3.2 Ligand-Binding Domain

Record Created:

Thursday, July 24, 2025 - 08:30

Gangwar, S. P., Green, M. N., Michard, E., Simon, A. A., Feijó, J. A., & Sobolevsky, A. I. (2021). Structure of the Arabidopsis Glutamate Receptor-like Channel GLR3.2 Ligand-Binding Domain. Structure, 29(2), 161-169.e4. https://doi.org/10.1016/j.str.2020.09.006

Authors:

Shanti Pal Gangwar

Marriah N. Green

Erwan Michard

Alexander A. Simon

José A. Feijó

Alexander I. Sobolevsky

Affiliated Authors:

Shanti Pal Gangwar

Marriah N. Green

Alexander I. Sobolevsky

Columbia Affiliation:

Author Keywords:

ca<sup>2+</sup> channels

glutamate receptor-like channels (glr)

ionotropic glutamate receptor (iglur)

plant

x-ray crystallography

Grants:

R01CA206573 (NIH – National Cancer Institute)

S10RR029205 (NIH – National Center for Research Resources)

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

R01GM131043 (NIH – National Institute of General Medical Sciences)

P30GM124165 (NIH – National Institute of General Medical Sciences)

R01NS083660 (NIH – National Institute of Neurological Disorders and Stroke)

R01NS107253 (NIH – National Institute of Neurological Disorders and Stroke)

Publication Type:

Article

Unique ID:

10.1016/j.str.2020.09.006

PMID:

33027636

DOI:

10.1016/j.str.2020.09.006

Journal:

Structure

Publication Date:

2021-02-04

Data Source:

Scopus

Source Link:

Nonconserved Long Intergenic Noncoding RNAs Associate With Complex Cardiometabolic Disease Traits

Record Created:

Wednesday, August 13, 2025 - 15:11

Foulkes, A. S., Selvaggi, C., Cao, T., O’Reilly, M. E., Cynn, E., Ma, P., Lumish, H., Xue, C., & Reilly, M. P. (2021). Nonconserved Long Intergenic Noncoding RNAs Associate With Complex Cardiometabolic Disease Traits. Arteriosclerosis, Thrombosis, and Vascular Biology, 41(1), 501–511. https://doi.org/10.1161/atvbaha.120.315045

Authors:

Andrea S. Foulkes

Caitlin Selvaggi

Tingyi Cao

Puyang Ma

Marcella E. O'Reilly

Esther Cynn

Heidi Lumish

Chenyi Xue

Muredach P. Reilly

Affiliated Authors:

Marcella E. O'Reilly

Esther Cynn

Heidi Lumish

Chenyi Xue

Muredach P. Reilly

Columbia Affiliation:

Subjects:

Cardiovascular Diseases (MeSH)

Metabolic Diseases (MeSH)

Multifactorial Inheritance (MeSH)

Polymorphism, Single Nucleotide (MeSH)

RNA, Long Noncoding (MeSH)

Synteny (MeSH)

Author Keywords:

genome wide association studies

cardiovascular diseases

complex traits

lincrnas

syntenic conservation

Grants:

R01HL113147 (NIH – National Heart, Lung, and Blood Institute)

R01HL132561 (NIH – National Heart, Lung, and Blood Institute)

K24HL107643 (NIH – National Heart, Lung, and Blood Institute)

T32DK007647 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

R15GM126485 (NIH – National Institute of General Medical Sciences)

R01GM127862 (NIH – National Institute of General Medical Sciences)

Publication Type:

Article

Unique ID:

10.1161/ATVBAHA.120.315045

PMID:

33176448

DOI:

10.1161/ATVBAHA.120.315045

Journal:

Arteriosclerosis, Thrombosis, and Vascular Biology

Publication Date:

2021-01-01

Data Source:

Web of Science

Source Link: