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Mielke, M. M., Evans, J. K., Neiberg, R. H., Molina-Henry, D. P., Marcovina, S. M., Johnson, K. C., Carmichael, O. T., Rapp, S. R., Sachs, B. C., Ding, J., Shappell, H. M., Luchsinger, J. A., Espeland, M. A., & Hayden, K. M. (2025). Alzheimer Disease Blood Biomarkers and Cognition Among Individuals With Diabetes and Overweight or Obesity. JAMA Network Open, 8(2), e2458149. https://doi.org/10.1001/jamanetworkopen.2024.58149

Elyaman, W., Stern, L. J., Jiang, N., Dressman, D., Bradley, P., Klatzmann, D., Bradshaw, E. M., Farber, D. L., Kent, S. C., Chizari, S., Funk, K., Devanand, D., Thakur, K. T., Raj, T., Dalahmah, O. A., Sarkis, R. A., Weiner, H. L., Shneider, N. A., & Przedborski, S. (2025). Exploring the role of T cells in Alzheimer’s and other neurodegenerative diseases: Emerging therapeutic insights from the T Cells in the Brain symposium. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14548

Pandey, N., Yang, Z., Cieza, B., Reyes-Dumeyer, D., Kang, M. S., Montesinos, R., Soto-Añari, M., Custodio, N., Honig, L. S., & Tosto, G. (2025). Plasma phospho-tau217 as a predictive biomarker for Alzheimer’s disease in a large south American cohort. Alzheimer’s Research & Therapy, 17(1). https://doi.org/10.1186/s13195-024-01655-w

Siemers, E., Feaster, T., Sethuraman, G., Sundell, K., Skljarevski, V., Cline, E. N., Zhang, H., Jerecic, J., Honig, L. S., Salloway, S., Sperling, R., Trame, M. N., Dodds, M. G., & Johnson, K. (2025). INTERCEPT-AD, a phase 1 study of intravenous sabirnetug in participants with mild cognitive impairment or mild dementia due to Alzheimer’s disease. The Journal of Prevention of Alzheimer’s Disease, 12(1), 100005. https://doi.org/10.1016/j.tjpad.2024.100005

Hammers, D. B., Eloyan, A., Thangarajah, M., Taurone, A., Beckett, L., Gao, S., Polsinelli, A. J., Kirby, K., Dage, J. L., Nudelman, K., Aisen, P., Reman, R., La Joie, R., Lagarde, J., Atri, A., Clark, D., Day, G. S., Duara, R., … Graff‐Radford, N. R. (2024). Differences in baseline cognitive performance between participants with early‐onset and late‐onset Alzheimer’s disease: Comparison of LEADS and ADNI. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14218

Hammers, D. B., Eloyan, A., Taurone, A., Thangarajah, M., Gao, S., Beckett, L., Polsinelli, A. J., Kirby, K., Dage, J. L., Nudelman, K., Aisen, P., Reman, R., La Joie, R., Lagarde, J., Atri, A., Clark, D., Day, G. S., Duara, R., … Graff‐Radford, N. R. (2024). Longitudinal cognitive performance of participants with sporadic early onset Alzheimer’s disease from LEADS. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14439

Gomez, M. L., Beecham, G., Montine, T. J., Cuccaro, M. L., Toga, A. W., Keene, C. D., Crane, P. K., Mukherjee, S., Panizzon, M. S., Biber, S. A., Kukull, W. A., Bennett, D. A., Barnes, L. L., Schneider, J. A., De Jager, P. L., Menon, V., Hohman, T. J., & Dumitrescu, L. C. (2024). Sex Specific Association of Apolipoprotein E Alleles with Autopsy Measures of Arteriolosclerosis and Atherosclerosis among Older Adults. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.091485

Gomez, N., Jean‐Francois, M., Hamilton‐Nelson, K. L., Slifer, S. H., Kunkle, B. W., Cuccaro, M. L., Martin, E. R., Haines, J. L., Reitz, C., Pericak‐Vance, M. A., Vardarajan, B. N., & Beecham, G. (2024). Linkage analyses identifiy novel loci for Alzheimer’s disease in non‐Hispanic white families. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.092913

Taga, M., Fujita, M., Parghi, N., & De Jager, P. L. (2024). Automated image segmentation uncovers the association of a microglial subtype defined by High CD74 Expression with cognitive decline. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.092664

Kumar, A., Ray, N. R., Zaman, A. F., Manoochehri, M., Stein, C., Mena, P. R., Sweet, R., Hohman, T. J., Cuccaro, M. L., Beecham, G. W., Huey, E. D., & Reitz, C. (2024). Disentangling the genetic underpinnings of neuropsychiatric symptoms in Alzheimer’s Disease in the Alzheimer’s Disease Sequencing Project: study design and methodology. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.092344

Damuka, N., Gollepalli, K. K., Krizan, I., Bhoopal, B., Miller, M., Deep, O., Bashetti, N., Kumar, J. S., Orr, M. E., Macauley, S. L., Whitlow, C. T., Mintz, A., Lockhart, S. N., Craft, S., & Sai, K. K. S. (2024). Exploring Microtubule Dynamics in Alzheimer’s Disease: Longitudinal Assessment Using [11C]MPC‐6827 PET Imaging in APP/PS1 and PS301S Mouse Models. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.090993

Kraal, A. Z., McFarlane, H. V., Pyne, J. D., Turney, I. C., Lao, P. J., Mazen, J., Brickman, A. M., & Manly, J. J. (2024). Does socioeconomic status modify the association between glycemic level and MRI markers of ADRD risk in middle‐aged adults? Alzheimer’s & Dementia, 20(S9). Portico. https://doi.org/10.1002/alz.094021

Hojjati, S. H., Butler, T. A., de Leon, M. J., Gupta, A. H., Nayak, S., Luchsinger, J. A., Chiang, G., & Razlighi, Q. R. (2024). Remote associations between beta‐amyloid and tau are mediated by between‐network connectivity. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.086460

Luquez, T., Sreenivas, D., Bennett, D. A., De Jager, P. L., & Menon, V. (2024). Cell type‐specific signatures of resilience to cognitive decline in the presence of brain pathologies. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.088929

Bahl, A., Honig, L. S., Kang, M. S., Sanchez, D., Reyes‐Dumeyer, D., Manly, J. J., Lantigua, R. A., Dage, J. L., Brickman, A. M., Vardarajan, B. N., Mayeux, R., & Gu, Y. (2024). Blood‐Based Biomarkers to Aid in Alzheimer’s Disease Prediction or Diagnosis: Analysis in a Multi‐Ethnic Cohort Study. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.091795

de la Colina, A. N., Charisis, S., Ntanasi, E., Mamalaki, E., Skaperda, Z., Kouretas, D., & Scarmeas, N. (2024). Comparison of cerebrospinal fluid and plasma oxidative stress biomarkers. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.085482

Karaahmet, B., Duquesne, L., Sigalov, A., Yung, C. J., Kroshilina, A., Zhang, Y., Taga, M., & Klein, H. (2024). Spatial Transcriptomics Analysis Identifies Glial Signatures Spatially Associated with Neuritic Plaques in Human Post‐Mortem Brains. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.087498

Castellano, T., Wang, T. C., Nolan, E., Archer, D. B., Cody, K., Harrison, T. M., Wu, Y., Durant, A., Janve, V. A., Engelman, C. D., Jagust, W. J., Albert, M. S., Johnson, S. C., Resnick, S. M., Sperling, R. A., Bilgel, M., Saykin, A. J., Vardarajan, B. N., Mayeux, R., … Koran, M. E. I. (2024). Genetic and Sex Associations with Earlier Estimated Onset of Amyloid Positivity from over 4000 Harmonized Positron Emission Tomography Images. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092852

Houlihan, H. M., Johnson, A. S., Smith, A. C., Guzmán, D. S., Okafor, A., Heuer, L. B., Talmasov, D., Chikwem, N., Dass, D. S., Noble, J. M., Kreisl, W. C., Small, S. A., & Lao, P. J. (2024). Microglia density measured by TSPO PET across amyloid positivity and clinical variants. Alzheimer’s & Dementia, 20(S8). Portico. https://doi.org/10.1002/alz.095057

Pandey, N., Honig, L. S., Reyes‐Dumeyer, D., Cieza, B., Montesinos, R., Cespedes, J., Soto‐Añari, M. F., Custodio, N., & Tosto, G. (2024). p‐tau217 in a large Peruvian cohort phenotyped for Alzheimer’s Disease. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.093382

Wadhwani, A. R., Goldberg, D., Wolk, D. A., Lee, E. B., Farrell, K. W., Crary, J. F., Bennett, D. A., De Jager, P. L., Schneider, J. A., Zhou, W., McMillan, C. T., & Group, P. W. (2024). Shared and Distinct Epigenetic Profiles in Primary Age‐Related Tauopathy and Alzheimer’s Disease: Insights into Tangle Formation and Spread. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.092601

McIntire, L. B., Mares, J., Costa, A. P., Lazarian, A., Wartchow, K. M., Dartora, W., Nuriel, T., & Menon, V. (2024). Commonalities in the lipid profile shift in ApoE ε4 risk variant and mild cognitive impairment highlight acyl chain remodeling. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.087508

Cieza, B., Yang, Z., Reyes‐Dumeyer, D., Lee, A. J., Dugger, B. N., Jin, L., Murray, M. E., Dickson, D. W., Pericak‐Vance, M. A., Vance, J. M., Foroud, T. M., Mayeux, R., & Tosto, G. (2024). Polytranscriptomic risk score for Alzheimer Disease in a large diverse multi‐center brain bank study. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.092971

Kumar, M., Jiang, S., Lorman, D., David, L., Soni, R., Kissner, M., Yang, M., & Myeku, N. (2024). The role of immunoproteasomes in modulating neuro‐inflammation in Alzheimer’s Disease. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.086577

Logue, M. W., Labadorf, A. T., O’Neill, N. K., Dickson, D. W., Flanagan, M. E., Franklin, E. E., Frosch, M. P., Gearing, M., Jin, L., Kofler, J., Lee, E. B., Mayeux, R., McKee, A. C., Miller, C. A., Murray, M. E., Nelson, P. T., Perrin, R. J., Schneider, J. A., Stein, T. D., … Farrer, L. A. (2024). Identification of differentially expressed genes in post‐mortem tissue from African American Alzheimer disease cases and controls. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.091575

Lippert, R. V., Edwards, N. C., Tosto, G., Pyne, J. D., Lao, P. J., & Brickman, A. M. (2024). Cumulative Incidence Rate Score for Alzheimer’s Disease Risk is Associated with White Matter Hyperintensity Volume in Older Adults Without Dementia. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092734

Siemers, E. R., Evans, E. E., Fisher, T. L., Boise, M., Foster, A., Leonard, J. E., Mishra, V., Mallow, C. L., Porsteinsson, A. P., Turner, R. S., Bond, W., Huffaker, J., Farlow, M. R., Honig, L. S., Sheldon, E., Townley, R. A., Winner, P., Norton, J., Holub, R., … Zauderer, M. (2024). Results of SIGNAL‐AD, a randomized, phase 1b/2 trial to evaluate safety and efficacy of targeting reactive astrocytes with pepinemab, SEMA4D blocking antibody, in people with mild Alzheimer’s dementia. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092538

Yang, H., Kivisäkk, P., Viera, A. M. R., Maa, C., Kirn, D., Bellier, J., Liu, L., Selkoe, D. J., Schneider, J. A., Bennett, D. A., Jager, P. L. D., Johnson, K. A., Sperling, R. A., Arnold, S. E., & Chhatwal, J. P. (2024). The relationship between amyloid‐β, plasma/brain GFAP, and neocortical tau: a Mendelian randomization study. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.091415

Jiang, S. (2024). Comprehensive aberrations of proteasome complex in Alzheimer’s disease. Alzheimer’s & Dementia, 20(S1). Portico. https://doi.org/10.1002/alz.089220

Fowler, S. L., Behr, T. S., Turkes, E., O’Brien, D. P., Cauhy, P. M., Rawlinson, I., Edmonds, M., Foiani, M. S., Schaler, A., Crowley, G., Bez, S., Ficulle, E., Tsefou, E., Fischer, R., Geary, B., Gaur, P., Miller, C., D’Acunzo, P., Levy, E., … Ryskeldi-Falcon, B. (2024). Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease. Nature Neuroscience. https://doi.org/10.1038/s41593-024-01801-5

Seifar, F., Fox, E. J., Shantaraman, A., Liu, Y., Dammer, E. B., Modeste, E., Duong, D. M., Yin, L., Trautwig, A. N., Guo, Q., Xu, K., Ping, L., Reddy, J. S., Allen, M., Quicksall, Z., Heath, L., Scanlan, J., Wang, E., Wang, M., … Seyfried, N. T. (2024). Large‐scale deep proteomic analysis in Alzheimer’s disease brain regions across race and ethnicity. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14360

Boerwinkle, A. H., Wisch, J. K., Handen, B. L., Head, E., Mapstone, M., Rafii, M. S., O’Bryant, S. E., Krinsky‐McHale, S. J., Lai, F., Rosas, H. D., Zaman, S., Lott, I. T., Tudorascu, D., Zammit, M., Brickman, A. M., Lee, J. H., & Ances, B. M. (2024). The mediating role of plasma glial fibrillary acidic protein in amyloid and tau pathology in Down’s syndrome. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14359

Aivalioti, E., Georgiopoulos, G., Tual-Chalot, S., Bampatsias, D., Delialis, D., Sopova, K., Drakos, S. G., Stellos, K., & Stamatelopoulos, K. (2024). Amyloid-beta metabolism in age-related neurocardiovascular diseases. European Heart Journal. https://doi.org/10.1093/eurheartj/ehae655

Lee, W., Choi, S. H., Shea, M. G., Cheng, P., Dombroski, B. A., Pitsillides, A. N., Heard‐Costa, N. L., Wang, H., Bulekova, K., Kuzma, A. B., Leung, Y. Y., Farrell, J. J., Lin, H., Kunkle, B. W., Naj, A., Blue, E. E., Nusetor, F., Wang, D., Boerwinkle, E., … Peloso, G. M. (2024). Association of common and rare variants with Alzheimer’s disease in more than 13,000 diverse individuals with whole‐genome sequencing from the Alzheimer’s Disease Sequencing Project. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14283

Jones, A. A., Ramos‐Miguel, A., Gicas, K. M., Petyuk, V. A., Leurgans, S. E., De Jager, P. L., Schneider, J. A., Bennett, D. A., Honer, W. G., & Casaletto, K. B. (2024). A multilayer network analysis of Alzheimer’s disease pathogenesis: Roles for p‐tau, synaptic peptides, and physical activity. Alzheimer’s & Dementia, 20(11), 8012–8027. Portico. https://doi.org/10.1002/alz.14286

Sewell, K. R., Doecke, J. D., Xiong, C., Benzinger, T., Masters, C. L., Laske, C., Jucker, M., Lopera, F., Gordon, B. A., Llibre‐Guerra, J., Levin, J., Huey, E. D., Hassenstab, J., Schofield, P. R., Day, G. S., Fox, N. C., Chhatwal, J., Ibanez, L., … Roh, J. H. (2024). Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer’s disease. Alzheimer’s & Dementia, 20(11), 7923–7939. Portico. https://doi.org/10.1002/alz.14270

Chung, Y.-M., Hu, C.-S., Sun, E., & Tseng, H. C. (2024). Morphological multiparameter filtration and persistent homology in mitochondrial image analysis. PLOS ONE, 19(9), e0310157. https://doi.org/10.1371/journal.pone.0310157

VandeBunte, A. M., Lee, H., Paolillo, E. W., Hsiung, G. R., Staffaroni, A. M., Saloner, R., Tartaglia, C., Yaffe, K., Knopman, D. S., Ramos, E. M., Rascovsky, K., Bozoki, A. C., Wong, B., Domoto‐Reilly, K., Snyder, A., Pressman, P., Mendez, M. F., Litvan, I., … Fields, J. A. (2024). Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14172

Reddy, J. S., Heath, L., Linden, A. V., Allen, M., Lopes, K. de P., Seifar, F., Wang, E., Ma, Y., Poehlman, W. L., Quicksall, Z. S., Runnels, A., Wang, Y., Duong, D. M., Yin, L., Xu, K., Modeste, E. S., Shantaraman, A., Dammer, E. B., Ping, L., … Ertekin‐Taner, N. (2024). Bridging the gap: Multi‐omics profiling of brain tissue in Alzheimer’s disease and older controls in multi‐ethnic populations. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14208

Chen, Q., Aguirre, L., Liang, G., Zhao, H., Dong, T., Borrego, F., de Rojas, I., Hu, Q., Reyes, C., Su, L.-Y., Zhang, B., Lechleiter, J. D., Göring, H. H. H., De Jager, P. L., Kleinman, J. E., Hyde, T. M., Li, P. P., Ruiz, A., Weinberger, D. R., … Ma, L. (2024). Identification of a specific APOE transcript and functional elements associated with Alzheimer’s disease. Molecular Neurodegeneration, 19(1). https://doi.org/10.1186/s13024-024-00751-7

Ropri, A. S., Lam, T. G., Kalia, V., Buchanan, H. M., Bartosch, A. M. W., Youth, E. H. H., Xiao, H., Ross, S. K., Jain, A., Chakrabarty, J. K., Kang, M. S., Boyett, D., Spinazzi, E. F., Iodice, G., McGovern, R. A., Honig, L. S., Brown, L. M., Miller, G. W., McKhann, G. M., & Teich, A. F. (2024). Alzheimer’s disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expression. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14194

Damuka, N., Irmen, R. E., Krizan, I., Miller, M., Gollapelli, K. K., Bhoopal, B., Deep, O., Bansode, A., Lockhart, S. N., Orr, M. E., Jadiya, P., Bashetti, N., Kumar, J. V. S., Mintz, A., Whitlow, C. T., Craft, S., Macauley, S. L., & Solingapuram Sai, K. K. (2024). Exploring microtubule dynamics in Alzheimer’s disease: Longitudinal assessment using [11C]MPC‐6827 PET imaging in rodent models of Alzheimer’s‐related pathology. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14083

Kim, H., Lee, S., Levine, A., Huber, B., Andrews, H., Kerner, N. A., Cohen, D., Carlson, S., Bell, S. A., Rivera, A. M., Gordon, M. L., Simoes, S., Devanand, Davangere. P., Brickman, A. M., Schneider, L. S., Harvey, P. D., & Goldberg, T. E. (2024). Novel measures of cognition and function for the AD spectrum in the Novel Measures for Alzheimer’s Disease Prevention Trials (NoMAD) project: Psychometric properties, convergent validation, and contrasts with established measures. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.13757

Mares, J., Costa, A. P., Dartora, W. J., Wartchow, K. M., Lazarian, A., Bennett, D. A., Nuriel, T., Menon, V., & McIntire, L. B. J. (2024). Brain and serum lipidomic profiles implicate Lands cycle acyl chain remodeling association with APOEε4 and mild cognitive impairment. Frontiers in Aging Neuroscience, 16. https://doi.org/10.3389/fnagi.2024.1419253

Feldman, H. H., Luchsinger, J. A., Léger, G. C., Taylor, C., Jacobs, D. M., Salmon, D. P., Edland, S. D., Messer, K., Revta, C., Flowers, S. A., Jones, K. S., Koulman, A., Yarasheski, K. E., Verghese, P. B., Venkatesh, V., Zetterberg, H., Durant, J., Lupo, J.-L., & Gibson, G. E. (2024). Protocol for a seamless phase 2A-phase 2B randomized double-blind placebo-controlled trial to evaluate the safety and efficacy of benfotiamine in patients with early Alzheimer’s disease (BenfoTeam). PLOS ONE, 19(5), e0302998. https://doi.org/10.1371/journal.pone.0302998

Wang, H.-P., Scalco, R., Saito, N., Beckett, L., Nguyen, M.-L., Huie, E. Z., Honig, L. S., DeCarli, C., Rissman, R. A., Teich, A. F., Mungas, D. M., Jin, L.-W., & Dugger, B. N. (2024). The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease. Acta Neuropathologica Communications, 12(1). https://doi.org/10.1186/s40478-024-01773-4

Oveisgharan, S., Yu, L., de Paiva Lopes, K., Petyuk, V. A., Tasaki, S., Vialle, R., Menon, V., Wang, Y., De Jager, P. L., Schneider, J. A., & Bennett, D. A. (2024). G-protein coupled estrogen receptor 1, amyloid-β, and tau tangles in older adults. Communications Biology, 7(1). https://doi.org/10.1038/s42003-024-06272-9

Al-Dalahmah, O., Lam, M., McInvale, J. J., Qu, W., Nguyen, T., Mun, J.-Y., Kwon, S., Ifediora, N., Mahajan, A., Humala, N., Winters, T., Angeles, E., Jakubiak, K. A., Kühn, R., Kim, Y. A., De Rosa, M. C., Doege, C. A., Paryani, F., Flowers, X., … Hargus, G. (2024). Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons. Cell Stem Cell, 31(5), 676-693.e10. https://doi.org/10.1016/j.stem.2024.03.013

Bhattarai, P., Gunasekaran, T. I., Belloy, M. E., Reyes-Dumeyer, D., Jülich, D., Tayran, H., Yilmaz, E., Flaherty, D., Turgutalp, B., Sukumar, G., Alba, C., McGrath, E. M., Hupalo, D. N., Bacikova, D., Le Guen, Y., Lantigua, R., Medrano, M., Rivera, D., Recio, P., … Vardarajan, B. N. (2024). Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease. Acta Neuropathologica, 147(1). https://doi.org/10.1007/s00401-024-02721-1