Prevalence and Impact of Down Syndrome

Displaying 1 - 19 of 19CSV
Aslam, M. M., Fan, K., Dang, L. T., Gorijala, P., Shi, R., Feingold, E., Xicota, L., Cohen, A. D., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Cruchaga, C., Lee, J. H., & Kamboh, M. I. (2024). Genome‐wide association of Amyloid imaging and plasma biomarkers in Adults with Down Syndrome. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092659
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Fan, K., Aslam, M. M., Dang, L. T., Gorijala, P., Shi, R., Feingold, E., Kamboh, M. I., Lee, J. H., Xicota, L., Cohen, A. D., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., & Cruchaga, C. (2024). Genome‐wide association of Tau imaging and plasma biomarkers in adults with Down Syndrome. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092615
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Lao, P. J., Edwards, N. C., Flores‐Aguilar, L., Rizvi, B., Smith, A. C., Tudorascu, D., Rosas, H. D., Yassa, M. A., Handen, B. L., Christian, B. T., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2024). Longitudinal changes in neuroimaging markers of small vessel disease: Implications for clinical trials. Alzheimer’s & Dementia, 20(S9). Portico. https://doi.org/10.1002/alz.094386
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Kennedy, J. T., Wisch, J. K., Gordon, B. A., Boerwinkle, A. H., Benzinger, T. L. S., Klunk, W. E., Rafii, M., O’Bryant, S. E., Price, J. C., Yassa, M. A., Sathishkumar, M., McMillan, L., Brickman, A. M., Lao, P. J., Laymon, C. M., Krinsky‐McHale, S. J., Lai, F., Rosas, H. D., … Hartley, S. L. (2024). Brain Volumetric Trajectories in Down Syndrome and Autosomal Dominant Alzheimer Disease. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.089313
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Edwards, N. C., Lao, P. J., Alshikho, M. J., Rizvi, B., Aguilar, L. F., Petersen, M., O’Bryant, S. E., Tudorascu, D., Handen, B. L., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2024). Independent and interactive contributions of cerebrovascular disease, neuroinflammation, and tau pathophysiology to Alzheimer’s disease‐related diagnostic conversion in adults with Down syndrome. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.087570
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Boerwinkle, A. H., Wisch, J. K., Handen, B. L., Head, E., Mapstone, M., Rafii, M. S., O’Bryant, S. E., Krinsky‐McHale, S. J., Lai, F., Rosas, H. D., Zaman, S., Lott, I. T., Tudorascu, D., Zammit, M., Brickman, A. M., Lee, J. H., & Ances, B. M. (2024). The mediating role of plasma glial fibrillary acidic protein in amyloid and tau pathology in Down’s syndrome. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14359
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Wisch, J. K., Gordon, B. A., Boerwinkle, A. H., Flores, S., McKay, N. S., Henson, R. L., Thippabhotla, S., Kennedy, J. T., Butt, O. H., Chen, C. D., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Tudorascu, D., Zammit, M. D., Cohen, A., Johnson, S. C., … Fagan, A. M. (2023). Cross‐sectional comparison of the role of tau burden among Down Syndrome Alzheimer disease and autosomal‐dominant Alzheimer disease. Alzheimer’s & Dementia, 19(S14). Portico. https://doi.org/10.1002/alz.079102
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Lao, P. J., Sedaghat, A., Edwards, N. C., Lippert, R. V., Rizvi, B., Smith, A. C., Tudorascu, D., Rosas, H. D., Yassa, M. A., Handen, B. L., Christian, B. T., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2023). Pseudo‐longitudinal trajectories of cerebrovascular disease biomarkers in adults with Down syndrome across the lifespan. Alzheimer’s & Dementia, 19(S10). Portico. https://doi.org/10.1002/alz.081900
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Kennedy, J. T., Dincer, A., Thippabhotla, S., Roman, J., Wisch, J. K., Gordon, B. A., Boerwinkle, A. H., Flores, S., Chen, C. D., Benzinger, T. L. S., Klunk, W. E., Rafii, M. S., O’Bryant, S. E., Price, J. C., Yassa, M. A., Sathishkumar, M., McMillan, L., Brickman, A. M., … Lao, P. J. (2023). Changes in cortical thickness along the Alzheimer disease continuum in people with Down syndrome. Alzheimer’s & Dementia, 19(S17). Portico. https://doi.org/10.1002/alz.079932
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Lao, P. J., Sedaghat, A., Edwards, N. C., Lippert, R. V., Rizvi, B., Smith, A. C., Tudorascu, D., Rosas, H. D., Yassa, M. A., Handen, B. L., Christian, B. T., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2023). Pseudo‐longitudinal trajectories of cerebrovascular disease biomarkers in adults with Down syndrome across the lifespan. Alzheimer’s & Dementia, 19(S13). Portico. https://doi.org/10.1002/alz.079407
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Gorijala, P., Aslam, M. M., Dang, L., Fernandez, V., Sung, Y. J., Fan, K., Feingold, E., Kamboh, M. I., Lee, J. H., & Cruchaga, C. (2023). Alzheimer’s polygenic risk score is associated with Dementia and memory phenotypes in Down syndrome. Alzheimer’s & Dementia, 19(S12). Portico. https://doi.org/10.1002/alz.074937
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Brickman, A. M., Lao, P. J., Edwards, N. C., Rizvi, B., Wilcock, D. M., Gutierrez, J., & Head, E. (2023). Cerebrovascular features of Alzheimer’s disease in adults with Down syndrome. Alzheimer’s & Dementia, 19(S12). Portico. https://doi.org/10.1002/alz.075678
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Dang, L. T., Petersen, M., Xicota, L., O’Bryant, S. E., Krinsky‐McHale, S. J., Mapstone, M., Kamboh, M. I., Cruchaga, C., Handen, B. L., Pang, D., Silverman, W., Schupf, N., & Lee, J. H. (2023). Genome‐wide association meta‐analysis of plasma neurofilament light levels in high‐risk adults with Down Syndrome. Alzheimer’s & Dementia, 19(S14). Portico. https://doi.org/10.1002/alz.079001
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Columbia Affiliation
Queder, N., Adams, J. N., Keator, D. B., McMillan, L., Sathishkumar, M., Taylor, L. M., Doran, E., Nguyen, D., Hom, C., Krinsky‐McHale, S. J., Price, J. C., Lai, F., Rosas, H. D., Petersen, M., O’Bryant, S. E., Brickman, A. M., Head, E., Mapstone, M., Schupf, N., … Yassa, M. A. (2023). Association Between Neuroimaging Biomarkers, Plasma NfL, and Memory Performance in Adults With Down Syndrome With and Without Dementia. Alzheimer’s & Dementia, 19(S17). Portico. https://doi.org/10.1002/alz.078029
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Queder, N., Adams, J. N., Keator, D. B., McMillan, L., Sathishkumar, M., Taylor, L. M., Doran, E., Nguyen, D., Hom, C., Krinsky‐McHale, S. J., Price, J. C., Lai, F., Rosas, H. D., Petersen, M., O’Bryant, S. E., Brickman, A. M., Head, E., Mapstone, M., Schupf, N., … Yassa, M. A. (2023). Association Between Neuroimaging Biomarkers, Plasma NfL, and Memory Performance in Adults With Down Syndrome With and Without Dementia. Alzheimer’s & Dementia, 19(S10). Portico. https://doi.org/10.1002/alz.081782
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Gorijala, P., Aslam, M. M., Dang, L. T., Xicota, L., Fernandez, M. V., Sung, Y. J., Fan, K., Feingold, E., Surace, E. I., Chhatwal, J. P., Hom, C. L., Hartley, S. L., Hassenstab, J., Perrin, R. J., Mapstone, M., Zaman, S. H., Ances, B. M., Kamboh, M. I., … Lee, J. H. (2023). Alzheimer’s polygenic risk scores are associated with cognitive phenotypes in Down syndrome. Alzheimer’s & Dementia, 20(2), 1038–1049. Portico. https://doi.org/10.1002/alz.13506
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