Prevalence and Impact of Down Syndrome

Subject Vocabulary

OpenAlex Topic

Unique ID

https://openalex.org/T11015

Longitudinal changes in neuroimaging markers of small vessel disease: Implications for clinical trials

Lao, P. J., Edwards, N. C., Flores‐Aguilar, L., Rizvi, B., Smith, A. C., Tudorascu, D., Rosas, H. D., Yassa, M. A., Handen, B. L., Christian, B. T., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2024). Longitudinal changes in neuroimaging markers of small vessel disease: Implications for clinical trials. Alzheimer’s & Dementia, 20(S9). Portico. https://doi.org/10.1002/alz.094386

Authors:

Patrick J. Lao

Natalie C. Edwards

Lisi Flores Aguilar

Batool Rizvi

Anna C. Smith

Dana Tudorascu

H. Diana Rosas

Michael A. Yassa

Benjamin L. Handen

Bradley T. Christian

José Gutierrez

Donna M. Wilcock

Elizabeth Head

Adam M. Brickman

Affiliated Authors:

Patrick J. Lao

Natalie C. Edwards

Anna C. Smith

José Gutierrez

Adam M. Brickman

Columbia Affiliation:

Subjects:

Frailty in Older Adults and Geriatric Care (OpenAlex Topic)

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Epidemiology and Implications of Multimorbidity in Healthcare (OpenAlex Topic)

Publication Type:

Conference Proceeding

Unique ID:

10.1002/alz.094386

DOI:

10.1002/alz.094386

Journal:

Alzheimer's and Dementia

Publication Date:

2024-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

View Web of Science Record

Record Created:

Monday, February 3, 2025 - 09:47

Brain Volumetric Trajectories in Down Syndrome and Autosomal Dominant Alzheimer Disease

Kennedy, J. T., Wisch, J. K., Gordon, B. A., Boerwinkle, A. H., Benzinger, T. L. S., Klunk, W. E., Rafii, M., O’Bryant, S. E., Price, J. C., Yassa, M. A., Sathishkumar, M., McMillan, L., Brickman, A. M., Lao, P. J., Laymon, C. M., Krinsky‐McHale, S. J., Lai, F., Rosas, H. D., … Hartley, S. L. (2024). Brain Volumetric Trajectories in Down Syndrome and Autosomal Dominant Alzheimer Disease. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.089313

Authors:

James Tyler Kennedy

Julie K. Wisch

Brian A. Gordon

Anna H. Boerwinkle

Tammie L.S. Benzinger

William E. Klunk

Michael S. Rafii

Sid E. O’Bryant

Julie C. Price

Michael A. Yassa

Mithra Sathishkumar

Liv McMillan

Adam M. Brickman

Patrick J. Lao

Charles M. Laymon

Sharon J. Krinsky‐McHale

Florence Lai

H. Diana Rosas

Sigan L. Hartley

Shahid Zaman

Ira T. Lott

Joseph H. Lee

Ricardo Allegri

Sarah Berman

Jasmeer P. Chhatwal

Helena C. Chui

Carlos Cruchaga

Martin R. Farlow

Gregory S. Day

Jae‐Hong Lee

Johannes Levin

Ralph N. Martins

Hiroshi Mori

Richard J. Perrin

Stephen Salloway

Raquel Sánchez‐Valle

Peter W. Schofield

Chengjie Xiong

Jason J. Hassenstab

Eric McDade

Randall J. Bateman

Benjamin L. Handen

Elizabeth Head

Nicole Schupf

Mark Mapstone

Bradley T. Christian

Beau M. Ances

Affiliated Authors:

Patrick J. Lao

Joseph H. Lee

Columbia Affiliation:

Taub Institute for Research on Alzheimer’s Disease and the Aging Brain

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.089313

DOI:

10.1002/alz.089313

Journal:

Alzheimer's and Dementia

Publication Date:

2024-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Monday, February 3, 2025 - 09:47

Independent and interactive contributions of cerebrovascular disease, neuroinflammation, and tau pathophysiology to Alzheimer’s disease‐related diagnostic conversion in adults with Down syndrome

Edwards, N. C., Lao, P. J., Alshikho, M. J., Rizvi, B., Aguilar, L. F., Petersen, M., O’Bryant, S. E., Tudorascu, D., Handen, B. L., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2024). Independent and interactive contributions of cerebrovascular disease, neuroinflammation, and tau pathophysiology to Alzheimer’s disease‐related diagnostic conversion in adults with Down syndrome. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.087570

Authors:

Natalie C. Edwards

Patrick J. Lao

Mohamad J. Alshikho

Batool Rizvi

Lisi Flores Aguilar

Melissa Petersen

Sid E. O’Bryant

Dana Tudorascu

Benjamin L. Handen

José Gutierrez

Donna M. Wilcock

Elizabeth Head

Adam M. Brickman

Affiliated Authors:

Natalie C. Edwards

Patrick J. Lao

Columbia Affiliation:

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Frailty in Older Adults and Geriatric Care (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.087570

DOI:

10.1002/alz.087570

Journal:

Alzheimer's and Dementia

Publication Date:

2024-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Monday, February 3, 2025 - 09:47

Genome‐wide association of Amyloid imaging and plasma biomarkers in Adults with Down Syndrome

Aslam, M. M., Fan, K., Dang, L. T., Gorijala, P., Shi, R., Feingold, E., Xicota, L., Cohen, A. D., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Cruchaga, C., Lee, J. H., & Kamboh, M. I. (2024). Genome‐wide association of Amyloid imaging and plasma biomarkers in Adults with Down Syndrome. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092659

Authors:

Muhammad Aslam

Kang‐Hsien Fan

Lam‐Ha Dang

Priyanka Gorijala

Ruyu Shi

Eleanor Feingold

Laura Xicota

Ann D. Cohen

Benjamin L. Handen

Bradley T. Christian

Elizabeth Head

Mark Mapstone

Carlos Cruchaga

Joseph H. Lee

M. Ilyas Kamboh

Affiliated Authors:

Lam‐Ha Dang

Laura Xicota

Joseph H. Lee

Columbia Affiliation:

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.092659

DOI:

10.1002/alz.092659

Journal:

Alzheimer's and Dementia

Publication Date:

2024-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Monday, February 3, 2025 - 09:47

Genome‐wide association of Tau imaging and plasma biomarkers in adults with Down Syndrome

Fan, K., Aslam, M. M., Dang, L. T., Gorijala, P., Shi, R., Feingold, E., Kamboh, M. I., Lee, J. H., Xicota, L., Cohen, A. D., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., & Cruchaga, C. (2024). Genome‐wide association of Tau imaging and plasma biomarkers in adults with Down Syndrome. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092615

Authors:

Kang‐Hsien Fan

Muhammad Aslam

Lam‐Ha Dang

Priyanka Gorijala

Ruyu Shi

Eleanor Feingold

M. Ilyas Kamboh

Joseph H. Lee

Laura Xicota

Ann D. Cohen

Benjamin L. Handen

Bradley T. Christian

Elizabeth Head

Mark Mapstone

Carlos Cruchaga

Affiliated Authors:

Lam‐Ha Dang

Joseph H. Lee

Laura Xicota

Columbia Affiliation:

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Analysis of Electrocardiogram Signals (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.092615

DOI:

10.1002/alz.092615

Journal:

Alzheimer's and Dementia

Publication Date:

2024-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Monday, February 3, 2025 - 09:47

The mediating role of plasma glial fibrillary acidic protein in amyloid and tau pathology in Down's syndrome

Boerwinkle, A. H., Wisch, J. K., Handen, B. L., Head, E., Mapstone, M., Rafii, M. S., O’Bryant, S. E., Krinsky‐McHale, S. J., Lai, F., Rosas, H. D., Zaman, S., Lott, I. T., Tudorascu, D., Zammit, M., Brickman, A. M., Lee, J. H., & Ances, B. M. (2024). The mediating role of plasma glial fibrillary acidic protein in amyloid and tau pathology in Down’s syndrome. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14359

Authors:

Anna H. Boerwinkle

Julie K. Wisch

Benjamin L. Handen

Elizabeth Head

Mark Mapstone

Michael S. Rafii

Sid E. O’Bryant

Sharon J. Krinsky‐McHale

Florence Lai

H. Diana Rosas

Shahid Zaman

Ira T. Lott

Dana L. Tudorascu

Matthew Zammit

Adam M. Brickman

Joseph H. Lee

Beau M. Ances

Affiliated Authors:

Adam M. Brickman

Joseph H. Lee

Columbia Affiliation:

Subjects:

Down Syndrome (MeSH)

Glial Fibrillary Acidic Protein (MeSH)

tau Proteins (MeSH)

Positron-Emission Tomography (MeSH)

Alzheimer Disease (MeSH)

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Mechanisms of Alzheimer's Disease (OpenAlex Topic)

Diagnosis and Management of Alzheimer's Disease (OpenAlex Topic)

Author Keywords:

alzheimer's disease

biomarkers

down's syndrome

plasma

amyloid

amyloid beta protein

amyloid beta-peptides

gfap protein, human

glial fibrillary acidic protein

tau proteins

tau protein

biological marker

adult

alzheimer disease

article

astrocytosis

chromosome mosaicism

chromosome translocation

controlled study

cross-sectional study

dementia

down syndrome

female

human

major clinical study

male

mild cognitive impairment

pathophysiology

positron emission tomography

protein blood level

sibling

trisomy 21

blood

brain

diagnostic imaging

metabolism

middle aged

pathology

humans

positron-emission tomography

Grants:

U01AG051412 (NIH – National Institute On Aging)

U19AG068054 (NIH – National Institute On Aging)

U01AG051406 (NIH – National Institute On Aging)

Publication Type:

Article

Unique ID:

10.1002/alz.14359

PMID:

39535359

DOI:

10.1002/alz.14359

Journal:

Alzheimer's and Dementia

Publication Date:

2024-11-13

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

View PubMed Record

View Scopus Record

View Web of Science Record

View Scopus Record

Record Created:

Tuesday, December 17, 2024 - 14:36

Genome‐wide association meta‐analysis of plasma neurofilament light levels in high‐risk adults with Down Syndrome

Dang, L. T., Petersen, M., Xicota, L., O’Bryant, S. E., Krinsky‐McHale, S. J., Mapstone, M., Kamboh, M. I., Cruchaga, C., Handen, B. L., Pang, D., Silverman, W., Schupf, N., & Lee, J. H. (2023). Genome‐wide association meta‐analysis of plasma neurofilament light levels in high‐risk adults with Down Syndrome. Alzheimer’s & Dementia, 19(S14). Portico. https://doi.org/10.1002/alz.079001

Authors:

Lam‐Ha Dang

Melissa Petersen

Laura Xicota

Sid E. O’Bryant

Sharon J. Krinsky‐McHale

Mark Mapstone

M. Ilyas Kamboh

Carlos Cruchaga

Benjamin L. Handen

Deborah Pang

Wayne Silverman

Nicole Schupf

Joseph H. Lee

Affiliated Authors:

Lam‐Ha Dang

Laura Xicota

Nicole Schupf

Joseph H. Lee

Columbia Affiliation:

Gertrude H. Sergievsky Center

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.079001

DOI:

10.1002/alz.079001

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:46

Association Between Neuroimaging Biomarkers, Plasma NfL, and Memory Performance in Adults With Down Syndrome With and Without Dementia

Queder, N., Adams, J. N., Keator, D. B., McMillan, L., Sathishkumar, M., Taylor, L. M., Doran, E., Nguyen, D., Hom, C., Krinsky‐McHale, S. J., Price, J. C., Lai, F., Rosas, H. D., Petersen, M., O’Bryant, S. E., Brickman, A. M., Head, E., Mapstone, M., Schupf, N., … Yassa, M. A. (2023). Association Between Neuroimaging Biomarkers, Plasma NfL, and Memory Performance in Adults With Down Syndrome With and Without Dementia. Alzheimer’s & Dementia, 19(S17). Portico. https://doi.org/10.1002/alz.078029

Authors:

Nazek Queder

Jenna N. Adams

David B. Keator

Liv McMillan

Mithra Sathishkumar

Lisa M. Taylor

Eric Doran

Dana Nguyen

Christy Hom

Sharon J. Krinsky‐McHale

Julie C. Price

Florence Lai

H. Diana Rosas

Melissa Petersen

Sid E. O’Bryant

Adam M. Brickman

Elizabeth Head

Mark Mapstone

Nicole Schupf

Wayne Silverman

Ira T. Lott

Michael A. Yassa

Affiliated Authors:

Adam M. Brickman

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Neurology

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Conference Proceeding

Unique ID:

10.1002/alz.078029

DOI:

10.1002/alz.078029

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:49

Association Between Neuroimaging Biomarkers, Plasma NfL, and Memory Performance in Adults With Down Syndrome With and Without Dementia

Authors:

Nazek Queder

Jenna N. Adams

David B. Keator

Liv McMillan

Mithra Sathishkumar

Lisa M. Taylor

Eric Doran

Dana Nguyen

Christy Hom

Sharon J. Krinsky‐McHale

Julie C. Price

Florence Lai

H. Diana Rosas

Melissa Petersen

Sid E. O’Bryant

Adam M. Brickman

Elizabeth Head

Mark Mapstone

Nicole Schupf

Wayne Silverman

Ira T. Lott

Michael A. Yassa

Affiliated Authors:

Adam M. Brickman

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Neurology

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Joint Publication

Unique ID:

10.1002/alz.081782

DOI:

10.1002/alz.081782

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:52

Cross‐sectional comparison of the role of tau burden among Down Syndrome Alzheimer disease and autosomal‐dominant Alzheimer disease

Wisch, J. K., Gordon, B. A., Boerwinkle, A. H., Flores, S., McKay, N. S., Henson, R. L., Thippabhotla, S., Kennedy, J. T., Butt, O. H., Chen, C. D., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Tudorascu, D., Zammit, M. D., Cohen, A., Johnson, S. C., … Fagan, A. M. (2023). Cross‐sectional comparison of the role of tau burden among Down Syndrome Alzheimer disease and autosomal‐dominant Alzheimer disease. Alzheimer’s & Dementia, 19(S14). Portico. https://doi.org/10.1002/alz.079102

Authors:

Julie K. Wisch

Brian A. Gordon

Anna H. Boerwinkle

Shaney Flores

Nicole S. McKay

Rachel L. Henson

Sharmila Thippabhotla

James Tyler Kennedy

Omar H. Butt

Charles D. Chen

Benjamin L. Handen

Bradley T. Christian

Elizabeth Head

Mark Mapstone

Dana L. Tudorascu

Matthew Zammit

Annie Cohen

Sterling C. Johnson

Anne M. Fagan

William E. Klunk

Michael S. Rafii

Sid E. O’Bryant

Julie C. Price

Nicole Schupf

Charles M. Laymon

Michael A. Yassa

David B. Keator

Sharon J. Krinsky‐McHale

Florence Lai

H. Diana Rosas

Sigan L. Hartley

Shahid Zaman

Ira T. Lott

Wayne Silverman

Patrick J. Lao

Adam M. Brickman

Joseph H. Lee

Ricardo Allegri

Sarah Berman

Jasmeer P. Chhatwal

Helena C. Chui

Carlos Cruchaga

Martin R. Farlow

Nick C. Fox

Alison Goate

Gregory S. Day

Neill R. Graff‐Radford

Mathias Jucker

Jae‐Hong Lee

Johannes Levin

Ralph N. Martins

Hiroshi Mori

Richard J. Perrin

Stephen Salloway

Raquel Sánchez‐Valle

Peter W. Schofield

Jingqin Luo

Suzanne E. Schindler

John C. Morris

Celeste M. Karch

Jason J. Hassenstab

Tammie L.S. Benzinger

Eric McDade

Randall J. Bateman

Beau M. Ances

Affiliated Authors:

Adam M. Brickman

Joseph H. Lee

Columbia Affiliation:

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Diagnosis and Management of Alzheimer's Disease (OpenAlex Topic)

Frailty in Older Adults and Geriatric Care (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.079102

DOI:

10.1002/alz.079102

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:46

Pseudo‐longitudinal trajectories of cerebrovascular disease biomarkers in adults with Down syndrome across the lifespan

Lao, P. J., Sedaghat, A., Edwards, N. C., Lippert, R. V., Rizvi, B., Smith, A. C., Tudorascu, D., Rosas, H. D., Yassa, M. A., Handen, B. L., Christian, B. T., Gutierrez, J., Wilcock, D. M., Head, E., & Brickman, A. M. (2023). Pseudo‐longitudinal trajectories of cerebrovascular disease biomarkers in adults with Down syndrome across the lifespan. Alzheimer’s & Dementia, 19(S10). Portico. https://doi.org/10.1002/alz.081900

Authors:

Patrick J. Lao

Amirreza Sedaghat

Natalie C. Edwards

Rafael V. Lippert

Batool Rizvi

Anna C. Smith

Dana L. Tudorascu

H. Diana Rosas

Michael A. Yassa

Benjamin L. Handen

Bradley T. Christian

José Gutierrez

Donna M. Wilcock

Elizabeth Head

Adam M. Brickman

Affiliated Authors:

Patrick J. Lao

Rafael V. Lippert

Anna C. Smith

Adam M. Brickman

Columbia Affiliation:

Taub Institute for Research on Alzheimer’s Disease and the Aging Brain

Subjects:

Frailty in Older Adults and Geriatric Care (OpenAlex Topic)

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Conference Proceeding

Unique ID:

10.1002/alz.081900

DOI:

10.1002/alz.081900

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:51

Changes in cortical thickness along the Alzheimer disease continuum in people with Down syndrome

Kennedy, J. T., Dincer, A., Thippabhotla, S., Roman, J., Wisch, J. K., Gordon, B. A., Boerwinkle, A. H., Flores, S., Chen, C. D., Benzinger, T. L. S., Klunk, W. E., Rafii, M. S., O’Bryant, S. E., Price, J. C., Yassa, M. A., Sathishkumar, M., McMillan, L., Brickman, A. M., … Lao, P. J. (2023). Changes in cortical thickness along the Alzheimer disease continuum in people with Down syndrome. Alzheimer’s & Dementia, 19(S17). Portico. https://doi.org/10.1002/alz.079932

Authors:

John A. Kennedy

Aylin Dincer

Sharmila Thippabhotla

June Roman

Julie K. Wisch

Brian A. Gordon

Anna H. Boerwinkle

Shaney Flores

Charles D. Chen

Tammie L.S. Benzinger

William E. Klunk

Michael S. Rafii

Sid E. O’Bryant

Julie C. Price

Michael A. Yassa

Mithra Sathishkumar

Liv McMillan

Adam M. Brickman

Patrick J. Lao

Charles M. Laymon

Sharon J. Krinsky‐McHale

Florence Lai

H. Diana Rosas

Sigan L. Hartley

Shahid Zaman

Ira T. Lott

Wayne Silverman

Joseph H. Lee

Ricardo Allegri

Sarah Berman

Jasmeer P. Chhatwal

Helena C. Chui

Carlos Cruchaga

Martin R. Farlow

Alison Goate

Gregory S. Day

Neill R. Graff‐Radford

Mathias Jucker

Jae‐Hong Lee

Johannes Levin

Ralph N. Martins

Hiroshi Mori

Richard J. Perrin

Stephen Salloway

Raquel Sánchez‐Valle

Chengjie Xiong

Celeste M. Karch

Jason J. Hassenstab

Eric McDade

Randall J. Bateman

Benjamin L. Handen

Elizabeth Head

Mark Mapstone

Bradley T. Christian

Beau M. Ances

Peter R. Schofield

Dominantly Inherited Alzheimer Network

Affiliated Authors:

Adam M. Brickman

Patrick J. Lao

Joseph H. Lee

Columbia Affiliation:

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Frailty in Older Adults and Geriatric Care (OpenAlex Topic)

Epidemiology and Implications of Multimorbidity in Healthcare (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.079932

DOI:

10.1002/alz.079932

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:52

Pseudo‐longitudinal trajectories of cerebrovascular disease biomarkers in adults with Down syndrome across the lifespan

Authors:

Patrick J. Lao

Amirreza Sedaghat

Natalie C. Edwards

Rafael V. Lippert

Batool Rizvi

Anna C. Smith

Dana L. Tudorascu

H. Diana Rosas

Michael A. Yassa

Benjamin L. Handen

Bradley T. Christian

José Gutierrez

Donna M. Wilcock

Elizabeth Head

Adam M. Brickman

Affiliated Authors:

Patrick J. Lao

Rafael V. Lippert

Anna C. Smith

Adam M. Brickman

Columbia Affiliation:

Taub Institute for Research on Alzheimer’s Disease and the Aging Brain

Subjects:

Frailty in Older Adults and Geriatric Care (OpenAlex Topic)

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Joint Publication

Unique ID:

10.1002/alz.079407

DOI:

10.1002/alz.079407

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:46

Alzheimer’s polygenic risk score is associated with Dementia and memory phenotypes in Down syndrome

Gorijala, P., Aslam, M. M., Dang, L., Fernandez, V., Sung, Y. J., Fan, K., Feingold, E., Kamboh, M. I., Lee, J. H., & Cruchaga, C. (2023). Alzheimer’s polygenic risk score is associated with Dementia and memory phenotypes in Down syndrome. Alzheimer’s & Dementia, 19(S12). Portico. https://doi.org/10.1002/alz.074937

Authors:

Priyanka Gorijala

Muhammad Muaaz Aslam

Lam‐Ha Dang

María Victoria Fernández

Yun Ju Sung

Kang‐Hsien Fan

Eleanor Feingold

M. Ilyas Kamboh

Joseph H. Lee

Carlos Cruchaga

Affiliated Authors:

Lam‐Ha Dang

Joseph H. Lee

Columbia Affiliation:

Taub Institute for Research on Alzheimer’s Disease and the Aging Brain

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.074937

DOI:

10.1002/alz.074937

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:52

Cerebrovascular features of Alzheimer’s disease in adults with Down syndrome

Brickman, A. M., Lao, P. J., Edwards, N. C., Rizvi, B., Wilcock, D. M., Gutierrez, J., & Head, E. (2023). Cerebrovascular features of Alzheimer’s disease in adults with Down syndrome. Alzheimer’s & Dementia, 19(S12). Portico. https://doi.org/10.1002/alz.075678

Authors:

Adam M. Brickman

Patrick J. Lao

Natalie C. Edwards

Batool Rizvi

Donna M. Wilcock

José Gutierrez

Elizabeth Head

Affiliated Authors:

Adam M. Brickman

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Neurology

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.075678

DOI:

10.1002/alz.075678

Journal:

Alzheimer's and Dementia

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Tuesday, July 30, 2024 - 11:54

Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome

Gorijala, P., Aslam, M. M., Dang, L. T., Xicota, L., Fernandez, M. V., Sung, Y. J., Fan, K., Feingold, E., Surace, E. I., Chhatwal, J. P., Hom, C. L., Hartley, S. L., Hassenstab, J., Perrin, R. J., Mapstone, M., Zaman, S. H., Ances, B. M., Kamboh, M. I., … Lee, J. H. (2023). Alzheimer’s polygenic risk scores are associated with cognitive phenotypes in Down syndrome. Alzheimer’s & Dementia, 20(2), 1038–1049. Portico. https://doi.org/10.1002/alz.13506

Authors:

Priyanka Gorijala

M Muaaz Aslam

Lam-Ha T Dang

L Xicota

Maria V Fernandez

Yun Ju Sung

Kang-Hsien Fan

Eleanor Feingold

Ezequiel I Surace

Jasmeer P Chhatwal

Christy L Hom

Sigan L Hartley

Jason Hassenstab

Richard J Perrin

Mark Mapstone

Shahid H Zaman

Beau M Ances

M Ilyas Kamboh

Joseph H Lee

Carlos Cruchaga

Affiliated Authors:

Lam-Ha T Dang

L Xicota

Joseph H Lee

Columbia Affiliation:

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Epidemiology and Implications of Multimorbidity in Healthcare (OpenAlex Topic)

Alzheimer Disease (MeSH)

Down Syndrome (MeSH)

Cognitive Dysfunction (MeSH)

Author Keywords:

amyloid precursor protein

apoliprotein e apoe

area under the curve

cerebrospinal fluid biomarkers

cognitive batteries

dominantly inherited alzheimer network

down syndrome

early-onset alzheimer's disease

early-onset autosomal dominant

genetic architecture

genetic risk factor

late-onset alzheimer's disease

polygenic risk score

psen1

psen2

sporadic late-onset alzheimer's disease

Grants:

U54HD090256 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)

P50HD105353 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)

U54HD087011 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)

UL1TR002373 (NIH – National Center for Advancing Translational Sciences)

UL1TR002345 (NIH – National Center for Advancing Translational Sciences)

UL1TR001857 (NIH – National Center for Advancing Translational Sciences)

UL1TR001414 (NIH – National Center for Advancing Translational Sciences)

UL1TR001873 (NIH – National Center for Advancing Translational Sciences)

P30AG062715 (NIH – National Institute On Aging)

R01AG044546 (NIH – National Institute On Aging)

RF1AG058501 (NIH – National Institute On Aging)

U01AG051406 (NIH – National Institute On Aging)

P30AG066519 (NIH – National Institute On Aging)

RF1AG074007 (NIH – National Institute On Aging)

P30AG066444 (NIH – National Institute On Aging)

U24AG021886 (NIH – National Institute On Aging)

P50AG005681 (NIH – National Institute On Aging)

P01AG003991 (NIH – National Institute On Aging)

RF1AG044546 (NIH – National Institute On Aging)

U19AG068054 (NIH – National Institute On Aging)

R01AG064877 (NIH – National Institute On Aging)

P50AG008702 (NIH – National Institute On Aging)

P30AG062421 (NIH – National Institute On Aging)

P01AG026276 (NIH – National Institute On Aging)

U19AG032438 (NIH – National Institute On Aging)

R01AG064614 (NIH – National Institute On Aging)

U01AG024904 (NIH – National Institute On Aging)

U01AG051412 (NIH – National Institute On Aging)

RF1AG071706 (NIH – National Institute On Aging)

RF1AG053303 (NIH – National Institute On Aging)

U01AG058922 (NIH – National Institute On Aging)

P50AG005133 (NIH – National Institute On Aging)

Publication Type:

Article

Unique ID:

10.1002/alz.13506

PMID:

37855447

DOI:

10.1002/alz.13506

Journal:

Alzheimer's and Dementia

Publication Date:

2023-10-19

Data Source:

PubMed

Source Link:

View PubMed Record

View Scopus Record

View OpenAlex Record

Record Created:

Friday, July 26, 2024 - 15:15

Early striatal amyloid signal in Down Syndrome: Comparison of PiB and Florbetapir PET

McLachlan, M., Price, J. C., Laymon, C. M., Garimella, A., Keator, D. B., Kreisl, W. C., Klunk, W. E., Fryer, T. D., McVea, A. K., DiFilippo, A. H., & Christian, B. T. (2022). Early striatal amyloid signal in Down Syndrome: Comparison of PiB and Florbetapir PET. Alzheimer’s & Dementia, 18(S5). Portico. https://doi.org/10.1002/alz.062459

Authors:

Max McLachlan

Julie C. Price

Charles M. Laymon

Arun Garimella

David B. Keator

William E. Klunk

Tim D. Fryer

Andrew K McVea

Alexandra H DiFilippo

Bradley T. Christian

Affiliated Authors:

William E. Klunk

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Diagnosis and Management of Alzheimer's Disease (OpenAlex Topic)

Mechanisms of Alzheimer's Disease (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.062459

DOI:

10.1002/alz.062459

Journal:

Alzheimer's and Dementia

Publication Date:

2022-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Friday, September 6, 2024 - 14:18

Sex differences in levels of plasma neurofilament light and total tau in adults with Down syndrome

Dang, L. T., Krinsky‐McHale, S. J., O’Bryant, S., Pang, D., Zigman, W. B., Silverman, W., Schupf, N., & Lee, J. H. (2021). Sex differences in levels of plasma neurofilament light and total tau in adults with Down syndrome. Alzheimer’s & Dementia, 17(S5). Portico. https://doi.org/10.1002/alz.055785

Authors:

Lam‐Ha Dang

Sharon J. Krinsky‐McHale

Sid E. O’Bryant

Deborah Pang

Warren B. Zigman

Wayne Silverman

Nicole Schupf

Joseph H. Lee

Affiliated Authors:

Lam‐Ha Dang

Nicole Schupf

Joseph H. Lee

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Epidemiology and Implications of Multimorbidity in Healthcare (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.055785

DOI:

10.1002/alz.055785

Journal:

Alzheimer's and Dementia

Publication Date:

2021-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Monday, April 28, 2025 - 12:40

Utility of total tau as a biomarker for Alzheimer’s disease among adults with Down syndrome

Petersen, M., Rafii, M. S., Zhang, F., Schupf, N., Hall, J. R., & O’Bryant, S. (2021). Utility of total tau as a biomarker for Alzheimer’s disease among adults with Down syndrome. Alzheimer’s & Dementia, 17(S4). Portico. https://doi.org/10.1002/alz.052886

Authors:

Melissa Petersen

Michael S. Rafii

Fan Zhang

Nicole Schupf

James Hall

Sid E. O’Bryant

Affiliated Authors:

Nicole Schupf

Subjects:

Prevalence and Impact of Down Syndrome (OpenAlex Topic)

Epidemiology and Implications of Multimorbidity in Healthcare (OpenAlex Topic)

Frailty in Older Adults and Geriatric Care (OpenAlex Topic)

Publication Type:

Article

Unique ID:

10.1002/alz.052886

DOI:

10.1002/alz.052886

Journal:

Alzheimer's and Dementia

Publication Date:

2021-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

Record Created:

Monday, April 28, 2025 - 12:40