Down Syndrome

Displaying 1 - 22 of 22CSV
Echeverry‐Quiceno, L. M., Llambrich, S., Heredia‐Lidón, Á., Giménez, S., Rozalem‐Aranha, M., Inampudi, P., Heuzé, Y., Sevillano, X., Fortea, J., & Martínez‐Abadías, N. (2025). Potential of facial biomarkers for Alzheimer’s disease and obstructive sleep apnea in Down syndrome and general population. The FASEB Journal, 39(6). Portico. https://doi.org/10.1096/fj.202403009r
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Columbia Affiliation
Hilgenkamp, T. I. M., Davidson, E., Diaz, K. M., Fleming, R., Foster Kirk, R., Hastert, M., Kim, J., Mann, S., Usseglio, J., Videlefsky, A., & Ptomey, L. (2025). Weight‐loss interventions for adolescents with Down syndrome: a systematic review. Obesity, 33(4), 632–658. Portico. https://doi.org/10.1002/oby.24233
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Boerwinkle, A. H., Wisch, J. K., Handen, B. L., Head, E., Mapstone, M., Rafii, M. S., O’Bryant, S. E., Krinsky‐McHale, S. J., Lai, F., Rosas, H. D., Zaman, S., Lott, I. T., Tudorascu, D., Zammit, M., Brickman, A. M., Lee, J. H., & Ances, B. M. (2024). The mediating role of plasma glial fibrillary acidic protein in amyloid and tau pathology in Down’s syndrome. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.14359
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Carmona-Iragui, M., O’Connor, A., Llibre-Guerra, J., Lao, P., Ashton, N. J., Fortea, J., & Sánchez-Valle, R. (2024). Clinical and research application of fluid biomarkers in autosomal dominant Alzheimer’s disease and Down syndrome. EBioMedicine, 108, 105327. https://doi.org/10.1016/j.ebiom.2024.105327
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Lao, P., Edwards, N., Flores-Aguilar, L., Alshikho, M., Rizvi, B., Tudorascu, D., Rosas, H. D., Yassa, M., Christian, B. T., Mapstone, M., Handen, B., Zimmerman, M. E., Gutierrez, J., Wilcock, D., Head, E., & Brickman, A. M. (2024). Cerebrovascular disease emerges with age and Alzheimer’s disease in adults with Down syndrome. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-61962-y
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Gansa, W., Da Rosa, J. M. C., Menon, K., Sazeides, C., Stewart, O., & Bogunovic, D. (2024). Dysregulation of the Immune System in a Natural History Study of 1299 Individuals with Down Syndrome. Journal of Clinical Immunology, 44(6). https://doi.org/10.1007/s10875-024-01725-6
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Wisch, J. K., McKay, N. S., Boerwinkle, A. H., Kennedy, J., Flores, S., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Rafii, M. S., O’Bryant, S. E., Price, J. C., Laymon, C. M., Krinsky-McHale, S. J., Lai, F., Rosas, H. D., Hartley, S. L., Zaman, S., Lott, I. T., … Mori, H. (2024). Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer’s disease: a cross-sectional study. The Lancet Neurology, 23(5), 500–510. https://doi.org/10.1016/s1474-4422(24)00084-x
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D’Acunzo, P., Argyrousi, E. K., Ungania, J. M., Kim, Y., DeRosa, S., Pawlik, M., Goulbourne, C. N., Arancio, O., & Levy, E. (2024). Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity. Molecular Neurodegeneration, 19(1). https://doi.org/10.1186/s13024-024-00721-z
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Adams, A. D., Lin, J., Bianchi, D. W., Bishop, L., Sato, T., Baxter, L. L., Hoffmann, V., Koehly, L., & Guedj, F. (2024). Embryonic statistical analyses reveal 2 growth phenotypes in mouse models of Down syndrome. American Journal of Obstetrics and Gynecology, 230(2), 258.e1-258.e11. https://doi.org/10.1016/j.ajog.2023.07.056
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Pandya, P., Levy, B., & Sistermans, E. A. (2023). Current controversies in prenatal diagnosis: Noninvasive prenatal testing should replace other screening strategies for fetal trisomies 13, 18, 21. Prenatal Diagnosis, 44(4), 381–388. Portico. https://doi.org/10.1002/pd.6477
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Luchsinger, J. A., Pang, D., Krinsky‐McHale, S. J., Schupf, N., Lee, J. H., Silverman, W., & Zigman, W. B. (2023). Obesity, diabetes and their metabolic correlates in middle‐aged adults with Down syndrome. Journal of Intellectual Disability Research, 68(3), 212–222. Portico. https://doi.org/10.1111/jir.13103
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Gorijala, P., Aslam, M. M., Dang, L. T., Xicota, L., Fernandez, M. V., Sung, Y. J., Fan, K., Feingold, E., Surace, E. I., Chhatwal, J. P., Hom, C. L., Hartley, S. L., Hassenstab, J., Perrin, R. J., Mapstone, M., Zaman, S. H., Ances, B. M., Kamboh, M. I., … Lee, J. H. (2023). Alzheimer’s polygenic risk scores are associated with cognitive phenotypes in Down syndrome. Alzheimer’s & Dementia, 20(2), 1038–1049. Portico. https://doi.org/10.1002/alz.13506
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Baruchel, A., Bourquin, J.-P., Crispino, J., Cuartero, S., Hasle, H., Hitzler, J., Klusmann, J.-H., Izraeli, S., Lane, A. A., Malinge, S., Rabin, K. R., Roberts, I., Ryeom, S., Tasian, S. K., & Wagenblast, E. (2023). Down syndrome and leukemia: from basic mechanisms to clinical advances. Haematologica, 108(10), 2570–2581. https://doi.org/10.3324/haematol.2023.283225
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Stanbouly, D., Steinberg, B., & Chuang, S.-K. (2022). What are the Soft Tissue Risk Factors for Obstructive Sleep Apnea in Patients with Down’s Syndrome? The Cleft Palate Craniofacial Journal, 60(8), 986–992. https://doi.org/10.1177/10556656221088171
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Columbia Affiliation
Fleming, V., Helsel, B. C., Ptomey, L. T., Rosas, H. D., Handen, B., Laymon, C., Christian, B. T., Head, E., Mapstone, M., Lai, F., Krinsky-McHale, S., Zaman, S., Ances, B. M., Lee, J. H., & Hartley, S. L. (2023). Weight Loss and Alzheimer’s Disease in Down Syndrome. Journal of Alzheimer’s Disease, 91(3), 1215–1227. https://doi.org/10.3233/jad-220865
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Boerwinkle, A. H., Gordon, B. A., Wisch, J., Flores, S., Henson, R. L., Butt, O. H., McKay, N., Chen, C. D., Benzinger, T. L. S., Fagan, A. M., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Rafii, M. S., O’Bryant, S., Lai, F., Rosas, H. D., Lee, J. H., … Xu, X. (2023). Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer’s disease: a cross-sectional study. The Lancet Neurology, 22(1), 55–65. https://doi.org/10.1016/s1474-4422(22)00408-2
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Moni, F., Petersen, M. E., Zhang, F., Lao, P. J., Zimmerman, M. E., Gu, Y., Gutierrez, J., Rizvi, B., Laing, K. K., Igwe, K. C., Sathishkumar, M., Keator, D., Andrews, H., Krinsky‐McHale, S., Head, E., Lee, J. H., Lai, F., Yassa, M. A., Rosas, H. D., … Brickman, A. M. (2022). Probing the proteome to explore potential correlates of increased Alzheimer’s‐related cerebrovascular disease in adults with Down syndrome. Alzheimer’s & Dementia, 18(10), 1744–1753. Portico. https://doi.org/10.1002/alz.12627
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Silverman, W., Krinsky‐McHale, S. J., Zigman, W. B., & Schupf, N. (2021). Adults with Down syndrome in randomized clinical trials targeting prevention of Alzheimer’s disease. Alzheimer’s & Dementia, 18(10), 1736–1743. Portico. https://doi.org/10.1002/alz.12520
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Dar, P., Jacobsson, B., MacPherson, C., Egbert, M., Malone, F., Wapner, R. J., Roman, A. S., Khalil, A., Faro, R., Madankumar, R., Edwards, L., Haeri, S., Silver, R., Vohra, N., Hyett, J., Clunie, G., Demko, Z., Martin, K., Rabinowitz, M., … Norton, M. E. (2022). Cell-free DNA screening for trisomies 21, 18, and 13 in pregnancies at low and high risk for aneuploidy with genetic confirmation. American Journal of Obstetrics and Gynecology, 227(2), 259.e1-259.e14. https://doi.org/10.1016/j.ajog.2022.01.019
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Janelidze, S., Christian, B. T., Price, J., Laymon, C., Schupf, N., Klunk, W. E., Lott, I., Silverman, W., Rosas, H. D., Zaman, S., Mapstone, M., Lai, F., Ances, B. M., Handen, B. L., & Hansson, O. (2022). Detection of Brain Tau Pathology in Down Syndrome Using Plasma Biomarkers. JAMA Neurology, 79(8), 797. https://doi.org/10.1001/jamaneurol.2022.1740
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Godown, J., Fountain, D., Bansal, N., Ameduri, R., Anderson, S., Beasley, G., Burstein, D., Knecht, K., Molina, K., Pye, S., Richmond, M., Spinner, J. A., Watanabe, K., West, S., Reinhardt, Z., Scheel, J., Urschel, S., Villa, C., & Hollander, S. A. (2022). Heart Transplantation in Children With Down Syndrome. Journal of the American Heart Association, 11(10). https://doi.org/10.1161/jaha.121.024883
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