DNA Methylation

Displaying 1 - 45 of 45CSV
Barcelona, V., Ray, M., Zhao, Y., Samari, G., Wu, H., Reho, P., McNeil, R., & Reddy, U. M. (2025). Epigenomic pathways from racism to preterm birth: secondary analysis of the Nulliparous Pregnancy Outcomes Study: monitoring Mothers-to-be (nuMoM2b) cohort study in the USA to examine how DNA methylation mediates the relationship between multilevel racism and preterm birth in black women: a study protocol. BMJ Open, 15(3), e091801. https://doi.org/10.1136/bmjopen-2024-091801
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Ahn, J., Hwang, I.-S., Park, M.-R., Rosa-Velazquez, M., Cho, I.-C., Relling, A. E., Hwang, S., & Lee, K. (2025). Evolutionary lineage-specific genomic imprinting at the ZNF791 locus. PLOS Genetics, 21(1), e1011532. https://doi.org/10.1371/journal.pgen.1011532
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Zhuang, X., Wang, Q., Joost, S., Ferrena, A., Humphreys, D. T., Li, Z., Blum, M., Krause, K., Ding, S., Landais, Y., Zhan, Y., Zhao, Y., Chaligne, R., Lee, J.-H., Carrasco, S. E., Bhanot, U. K., Koche, R. P., Bott, M. J., Katajisto, P., … Tammela, T. (2024). Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis. Nature, 637(8044), 184–194. https://doi.org/10.1038/s41586-024-08285-0
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Pelland-Marcotte, M.-C., Belaktib, A., Droit, A., Remy, M. M., Clement, J. G., Bianco, S., Ma, Y., Liu, J., Herrmann, L., Raufaste-Cazavieille, V., Joly-Beauparlant, C., Mangnier, L., Leclercq, M., Sontag, T., Caron, M., St-Onge, P., Langlois, S., Koch, V., Flamand, Y., … Santiago, R. (2024). Molecular signatures associated with venous thromboembolism in children with acute lymphoblastic leukemia. Journal of Thrombosis and Haemostasis. https://doi.org/10.1016/j.jtha.2024.12.007
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Conway, K., Edmiston, S. N., Vondras, A., Reiner, A., Corcoran, D. L., Shen, R., Parrish, E. A., Hao, H., Lin, L., Kenney, J. M., Ilelaboye, G., Kostrzewa, C. E., Kuan, P. F., Busam, K. J., Lezcano, C., Lee, T. K., Hernando, E., Googe, P. B., Ollila, D. W., … Rainka, M. (2024). DNA Methylation Classes of Stage II and III Primary Melanomas and Their Clinical and Prognostic Significance. JCO Precision Oncology, 8. https://doi.org/10.1200/po-24-00375
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Abhimanyu, Longlax, S. C., Nishiguchi, T., Ladki, M., Sheikh, D., Martinez, A. L., Mace, E. M., Grimm, S. L., Caldwell, T., Portillo Varela, A., Sekhar, R. V., Mandalakas, A. M., Mlotshwa, M., Ginidza, S., Cirillo, J. D., Wallis, R. S., Netea, M. G., van Crevel, R., Coarfa, C., & DiNardo, A. R. (2024). TCA metabolism regulates DNA hypermethylation in LPS andMycobacterium tuberculosis–induced immune tolerance. Proceedings of the National Academy of Sciences, 121(41). https://doi.org/10.1073/pnas.2404841121
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Shen, Y., Domingo-Relloso, A., Kupsco, A., Kioumourtzoglou, M.-A., Tellez-Plaza, M., Umans, J. G., Fretts, A. M., Zhang, Y., Schnatz, P. F., Casanova, R., Martin, L. W., Horvath, S., Manson, J. E., Cole, S. A., Wu, H., Whitsel, E. A., Baccarelli, A. A., Navas-Acien, A., & Gao, F. (2024). AESurv: autoencoder survival analysis for accurate early prediction of coronary heart disease. Briefings in Bioinformatics, 25(6). https://doi.org/10.1093/bib/bbae479
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Quintana-Feliciano, R., Kottur, J., Ni, M., Ghosh, R., Salas-Estrada, L., Ahlsen, G., Rechkoblit, O., Shapiro, L., Filizola, M., Fang, G., & Aggarwal, A. K. (2024). Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52130-x
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Lieberman-Cribbin, W., Domingo-Relloso, A., Glabonjat, R. A., Schilling, K., Cole, S. A., O’Leary, M., Best, L. G., Zhang, Y., Fretts, A. M., Umans, J. G., Goessler, W., Navas-Acien, A., Tellez-Plaza, M., & Kupsco, A. (2024). An epigenome-wide study of selenium status and DNA methylation in the Strong Heart Study. Environment International, 191, 108955. https://doi.org/10.1016/j.envint.2024.108955
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Gretarsson, K. H., Abini-Agbomson, S., Gloor, S. L., Weinberg, D. N., McCuiston, J. L., Kumary, V. U. S., Hickman, A. R., Sahu, V., Lee, R., Xu, X., Lipieta, N., Flashner, S., Adeleke, O. A., Popova, I. K., Taylor, H. F., Noll, K., Windham, C. L., Maryanski, D. N., Venters, B. J., … Lu, C. (2024). Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch. Science Advances, 10(35). https://doi.org/10.1126/sciadv.adp0975
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Wan, Z., Chibnik, L. B., Valeri, L., Hughes, T. M., Blacker, D., & Ma, Y. (2024). DNA Methylation Mediates the Association Between Cardiometabolic Risk Factors and Cognition: Findings From the Health and Retirement Study. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 79(8). https://doi.org/10.1093/gerona/glae167
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Taylor, B., Zhao, Y., Perez, N. B., Potts-Thompson, S., Crusto, C., Creber, R. M., & Taylor, J. Y. (2024). Epigenome-Wide Association Study of Depressive Symptoms in Black Women in the InterGEN Study. International Journal of Molecular Sciences, 25(14), 7681. https://doi.org/10.3390/ijms25147681
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Columbia Affiliation
Aiello, A. E., Mishra, A. A., Martin, C. L., Levitt, B., Gaydosh, L., Belsky, D. W., Hummer, R. A., Umberson, D. J., & Harris, K. M. (2024). Familial Loss of a Loved One and Biological Aging. JAMA Network Open, 7(7), e2421869. https://doi.org/10.1001/jamanetworkopen.2024.21869
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Maunakea, A. K., Phankitnirundorn, K., Peres, R., Dye, C., Juarez, R., Walsh, C., Slavens, C., Park, S. L., Wilkens, L. R., & Le Marchand, L. (2024). Socioeconomic Status, Lifestyle, and DNA Methylation Age Among Racially and Ethnically Diverse Adults. JAMA Network Open, 7(7), e2421889. https://doi.org/10.1001/jamanetworkopen.2024.21889
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Shiau, S., Zumpano, F., Wang, Z., Shah, J., Tien, P. C., Ross, R. D., Sharma, A., & Yin, M. T. (2024). Epigenetic Aging and Musculoskeletal Outcomes in a Cohort of Women Living With HIV. The Journal of Infectious Diseases, 229(6), 1803–1811. https://doi.org/10.1093/infdis/jiae016
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Chen, J., Moubadder, L., Clausing, E. S., Kezios, K. L., Conneely, K. N., Hüls, A., Baccarelli, A., Factor-Litvak, P., Cirrillo, P., Shelton, R. C., Link, B. G., & Suglia, S. F. (2024). Associations of childhood, adolescence, and midlife cognitive function with DNA methylation age acceleration in midlife. Aging, 16(11), 9350–9368. https://doi.org/10.18632/aging.205943
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Cheng, M., Conley, D., Kuipers, T., Li, C., Ryan, C. P., Taeubert, M. J., Wang, S., Wang, T., Zhou, J., Schmitz, L. L., Tobi, E. W., Heijmans, B. T., Lumey, L. H., & Belsky, D. W. (2024). Accelerated biological aging six decades after prenatal famine exposure. Proceedings of the National Academy of Sciences, 121(24). https://doi.org/10.1073/pnas.2319179121
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Lee, M. K., Azizgolshani, N., Zhang, Z., Perreard, L., Kolling, F. W., Nguyen, L. N., Zanazzi, G. J., Salas, L. A., & Christensen, B. C. (2024). Associations in cell type-specific hydroxymethylation and transcriptional alterations of pediatric central nervous system tumors. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-47943-9
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Taylor, J. Y., Jones-Patten, A., Prescott, L., Potts-Thompson, S., Joyce, C., Tayo, B., & Saban, K. (2024). The race-based stress reduction intervention (RiSE) study on African American women in NYC and Chicago: Design and methods for complex genomic analysis. PLOS ONE, 19(4), e0295293. https://doi.org/10.1371/journal.pone.0295293
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Eisenberg, D. T. A., Ryan, C. P., Lee, N. R., Carba, D. B., MacIsaac, J. L., Dever, K., Atashzay, P., Kobor, M. S., & Kuzawa, C. (2024). DNA methylation-based estimators of telomere length show low correspondence with paternal age at conception and other measures of external validity of telomere length. GeroScience, 46(4), 3957–3969. https://doi.org/10.1007/s11357-024-01114-2
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Dye, C. K., Wu, H., Jackson, G. L., Kidane, A., Nkambule, R., Lukhele, N. G., Malinga, B. P., Chekenyere, R., El-Sadr, W. M., Baccarelli, A. A., & Harris, T. G. (2024). Epigenetic aging in older people living with HIV in Eswatini: a pilot study of HIV and lifestyle factors and epigenetic aging. Clinical Epigenetics, 16(1). https://doi.org/10.1186/s13148-024-01629-7
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Raffington, L., Schwaba, T., Aikins, M., Richter, D., Wagner, G. G., Harden, K. P., Belsky, D. W., & Tucker-Drob, E. M. (2023). Associations of socioeconomic disparities with buccal DNA-methylation measures of biological aging. Clinical Epigenetics, 15(1). https://doi.org/10.1186/s13148-023-01489-7
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Fang, F., Zhou, L., Perng, W., Marsit, C. J., Knight, A. K., Cardenas, A., Aung, M. T., Hivert, M.-F., Aris, I. M., Goodrich, J. M., Smith, A. K., Gaylord, A., Fry, R. C., Oken, E., O’Connor, G., Ruden, D. M., Trasande, L., Herbstman, J. B., … Camargo, C. A. (2023). Evaluation of pediatric epigenetic clocks across multiple tissues. Clinical Epigenetics, 15(1). https://doi.org/10.1186/s13148-023-01552-3
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Columbia Affiliation
Sha, Q., Fu, Z., Escobar Galvis, M. L., Madaj, Z., Underwood, M. D., Steiner, J. A., Dwork, A., Simpson, N., Galfalvy, H., Rozoklija, G., Achtyes, E. D., Mann, J. J., & Brundin, L. (2023). Integrative transcriptome- and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls. Molecular Psychiatry, 29(1), 134–145. https://doi.org/10.1038/s41380-023-02311-9
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Domingo-Relloso, A., Joehanes, R., Rodriguez-Hernandez, Z., Lahousse, L., Haack, K., Fallin, M. D., Herreros-Martinez, M., Umans, J. G., Best, L. G., Huan, T., Liu, C., Ma, J., Yao, C., Jerolon, A., Bermudez, J. D., Cole, S. A., Rhoades, D. A., Levy, D., Navas-Acien, A., & Tellez-Plaza, M. (2023). Smoking, blood DNA methylation sites and lung cancer risk. Environmental Pollution, 334, 122153. https://doi.org/10.1016/j.envpol.2023.122153
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Scorza, P., Duarte, C. S., Lee, S., Wu, H., Posner, J., Baccarelli, A., & Monk, C. (2023). Stage 2 Registered Report: Epigenetic Intergenerational Transmission: Mothers’ Adverse Childhood Experiences and DNA Methylation. Journal of the American Academy of Child & Adolescent Psychiatry, 62(10), 1110–1122. https://doi.org/10.1016/j.jaac.2023.02.018
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Boyer, K., Domingo-Relloso, A., Jiang, E., Haack, K., Goessler, W., Zhang, Y., Umans, J. G., Belsky, D. W., Cole, S. A., Navas-Acien, A., & Kupsco, A. (2023). Metal mixtures and DNA methylation measures of biological aging in American Indian populations. Environment International, 178, 108064. https://doi.org/10.1016/j.envint.2023.108064
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Xu, R., Hong, X., Ladd-Acosta, C., Buckley, J. P., Choi, G., Wang, G., Hou, W., Wang, X., Liang, L., & Ji, H. (2023). Contrasting Association of Maternal Plasma Biomarkers of Smoking and 1-Carbon Micronutrients with Offspring DNA Methylation: Evidence of Aryl Hydrocarbon Receptor Repressor Gene–Smoking–Folate Interaction. The Journal of Nutrition, 153(8), 2339–2351. https://doi.org/10.1016/j.tjnut.2023.05.002
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Nakamura, A., Broséus, L., Tost, J., Vaiman, D., Martins, S., Keyes, K., Bonello, K., Fekom, M., Strandberg-Larsen, K., Sutter-Dallay, A.-L., Heude, B., Melchior, M., & Lepeule, J. (2023). Epigenome-Wide Associations of Placental DNA Methylation and Behavioral and Emotional Difficulties in Children at 3 Years of Age. International Journal of Molecular Sciences, 24(14), 11772. https://doi.org/10.3390/ijms241411772
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Hahn, J., Bressler, J., Domingo-Relloso, A., Chen, M.-H., McCartney, D. L., Teumer, A., van Dongen, J., Kleber, M. E., Aïssi, D., Swenson, B. R., Yao, J., Zhao, W., Huang, J., Xia, Y., Brown, M. R., Costeira, R., de Geus, E. J. C., Delgado, G. E., Dobson, D. A., … de Vries, P. S. (2023). DNA methylation analysis is used to identify novel genetic loci associated with circulating fibrinogen levels in blood. Journal of Thrombosis and Haemostasis, 21(5), 1135–1147. https://doi.org/10.1016/j.jtha.2023.01.015
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Parsons, E., Rifas-Shiman, S. L., Bozack, A. K., Baccarelli, A. A., DeMeo, D. L., Hivert, M.-F., Godderis, L., Duca, R.-C., Oken, E., & Cardenas, A. (2022). Prenatal trimester-specific intake of micronutrients: global DNA methylation and hydroxymethylation at birth and persistence in childhood. Journal of Developmental Origins of Health and Disease, 14(2), 311–318. https://doi.org/10.1017/s2040174422000642
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Waziry, R., Ryan, C. P., Corcoran, D. L., Huffman, K. M., Kobor, M. S., Kothari, M., Graf, G. H., Kraus, V. B., Kraus, W. E., Lin, D. T. S., Pieper, C. F., Ramaker, M. E., Bhapkar, M., Das, S. K., Ferrucci, L., Hastings, W. J., Kebbe, M., Parker, D. C., Racette, S. B., … Belsky, D. W. (2023). Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial. Nature Aging. https://doi.org/10.1038/s43587-022-00357-y
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Wielscher, M., Mandaviya, P. R., Kuehnel, B., Joehanes, R., Mustafa, R., Robinson, O., Zhang, Y., Bodinier, B., Walton, E., Mishra, P. P., Schlosser, P., Wilson, R., Tsai, P.-C., Palaniswamy, S., Marioni, R. E., Fiorito, G., Cugliari, G., Karhunen, V., Ghanbari, M., … Järvelin, M.-R. (2022). DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29792-6
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Parada, H., Sahrai, L., Wolff, M. S., Santella, R. M., Chen, J., Neugut, A. I., & Teitelbaum, S. L. (2022). Urinary parabens and breast cancer risk: Modification by LINE‐1 and LUMA global DNA methylation, and associations with breast cancer defined by tumor promoter methylation status. Molecular Carcinogenesis, 61(11), 1002–1015. Portico. https://doi.org/10.1002/mc.23456
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Kuzawa, C. W., Ryan, C. P., Adair, L. S., Lee, N. R., Carba, D. B., MacIsaac, J. L., Dever, K., Atashzay, P., Kobor, M. S., & McDade, T. W. (2022). Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines. Epigenetics, 17(11), 1535–1545. https://doi.org/10.1080/15592294.2022.2070105
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Oluwayiose, O. A., Wu, H., Gao, F., Baccarelli, A. A., Sofer, T., & Pilsner, J. R. (2022). Aclust2.0: a revamped unsupervised R tool for Infinium methylation beadchips data analyses. Bioinformatics, 38(20), 4820–4822. https://doi.org/10.1093/bioinformatics/btac583
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Bozack, A. K., Colicino, E., Just, A. C., Wright, R. O., Baccarelli, A. A., Wright, R. J., & Lee, A. G. (2021). Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples. Epigenetics, 17(10), 1080–1097. https://doi.org/10.1080/15592294.2021.1985300
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Barcelona, V., Huang, Y., Caceres, B. A., Newhall, K. P., Hui, Q., Cerdeña, J. P., Crusto, C. A., Sun, Y. V., & Taylor, J. Y. (2022). Experiences of Trauma and DNA Methylation Profiles among African American Mothers and Children. International Journal of Molecular Sciences, 23(16), 8951. https://doi.org/10.3390/ijms23168951
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Lee, M., Huan, T., McCartney, D. L., Chittoor, G., de Vries, M., Lahousse, L., Nguyen, J. N., Brody, J. A., Castillo-Fernandez, J., Terzikhan, N., Qi, C., Joehanes, R., Min, J. L., Smilnak, G. J., Shaw, J. R., Yang, C. X., Colicino, E., Hoang, T. T., Bermingham, M. L., … London, S. J. (2022). Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis. American Journal of Respiratory and Critical Care Medicine, 206(3), 321–336. https://doi.org/10.1164/rccm.202108-1907oc
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Lee, A. G., Tignor, N., Cowell, W., Colicino, E., Bozack, A., Baccarelli, A., Wang, P., & Wright, R. J. (2022). Associations between antenatal maternal asthma status and placental DNA methylation. Placenta, 126, 184–195. https://doi.org/10.1016/j.placenta.2022.06.008
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Solomon, O., Huen, K., Yousefi, P., Küpers, L. K., González, J. R., Suderman, M., Reese, S. E., Page, C. M., Gruzieva, O., Rzehak, P., Gao, L., Bakulski, K. M., Novoloaca, A., Allard, C., Pappa, I., Llambrich, M., Vives, M., Jima, D. D., Kvist, T., … Holland, N. (2022). Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutation Research/Reviews in Mutation Research, 789, 108415. https://doi.org/10.1016/j.mrrev.2022.108415
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Raffington, L., & Belsky, D. W. (2022). Integrating DNA Methylation Measures of Biological Aging into Social Determinants of Health Research. Current Environmental Health Reports, 9(2), 196–210. https://doi.org/10.1007/s40572-022-00338-8
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Schlosser, P., Tin, A., Matias-Garcia, P. R., Thio, C. H. L., Joehanes, R., Liu, H., Weihs, A., Yu, Z., Hoppmann, A., Grundner-Culemann, F., Min, J. L., Adeyemo, A. A., Agyemang, C., Ärnlöv, J., Aziz, N. A., Baccarelli, A., Bochud, M., Brenner, H., Breteler, M. M. B., … Teumer, A. (2021). Meta-analyses identify DNA methylation associated with kidney function and damage. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-27234-3
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Roostaei, T., Klein, H.-U., Ma, Y., Felsky, D., Kivisäkk, P., Connor, S. M., Kroshilina, A., Yung, C., Kaskow, B. J., Shao, X., Rhead, B., Ordovás, J. M., Absher, D. M., Arnett, D. K., Liu, J., Patsopoulos, N., Barcellos, L. F., Weiner, H. L., & De Jager, P. L. (2021). Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-27427-w
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