TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance

Abhimanyu, Longlax, S. C., Nishiguchi, T., Ladki, M., Sheikh, D., Martinez, A. L., Mace, E. M., Grimm, S. L., Caldwell, T., Portillo Varela, A., Sekhar, R. V., Mandalakas, A. M., Mlotshwa, M., Ginidza, S., Cirillo, J. D., Wallis, R. S., Netea, M. G., van Crevel, R., Coarfa, C., & DiNardo, A. R. (2024). TCA metabolism regulates DNA hypermethylation in LPS andMycobacterium tuberculosis–induced immune tolerance. Proceedings of the National Academy of Sciences, 121(41). https://doi.org/10.1073/pnas.2404841121
Authors:
Abhimanyu
Santiago Carrero Longlax
Tomoki Nishiguchi
Malik Ladki
Daanish Sheikh
Amera L Martinez
Emily M Mace
Sandra L Grimm
Thaleia Caldwell
Alexandra Portillo Varela
Rajagopal V Sekhar
Anna M Mandalakas
Mandla Mlotshwa
Sibuse Ginidza
Jeffrey D Cirillo
Robert S Wallis
Mihai G Netea
Reinout van Crevel
Cristian Coarfa
Andrew R DiNardo
Affiliated Authors:
Emily M Mace
Columbia Affiliation:
Subjects:
DNA Methylation (MeSH)
Mycobacterium tuberculosis (MeSH)
Lipopolysaccharides (MeSH)
Citric Acid Cycle (MeSH)
Immune Tolerance (MeSH)
Tuberculosis (MeSH)
Author Keywords:
immune tolerance
dna methylation
tuberculosis
sepsis
rheostat
elink
Publication Type:
Article
Unique ID:
10.1073/pnas.2404841121
PMID:
39348545
DOI:
10.1073/pnas.2404841121
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: