Nature Cancer
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Efe, G., Rustgi, A. K., & Prives, C. (2024). p53 at the crossroads of tumor immunity. Nature Cancer, 5(7), 983–995. https://doi.org/10.1038/s43018-024-00796-z
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Guida, J. L., Hyun, G., Belsky, D. W., Armstrong, G. T., Ehrhardt, M. J., Hudson, M. M., Green, P. A., Robison, L. L., Streck, B. P., Tonorezos, E. S., Yasui, Y., Wilson, C. L., Wang, Z., & Ness, K. K. (2024). Associations of seven measures of biological age acceleration with frailty and all-cause mortality among adult survivors of childhood cancer in the St. Jude Lifetime Cohort. Nature Cancer, 5(5), 731–741. https://doi.org/10.1038/s43018-024-00745-w
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Mellgard, G. S., Fojo, T., & Bates, S. E. (2024). Lessons from withdrawn accelerated approvals in oncology. Nature Cancer, 5(2), 211–215. https://doi.org/10.1038/s43018-023-00696-8
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Rogava, M., Aprati, T. J., Chi, W.-Y., Melms, J. C., Hug, C., Davis, S. H., Earlie, E. M., Chung, C., Deshmukh, S. K., Wu, S., Sledge, G., Tang, S., Ho, P., Amin, A. D., Caprio, L., Gurjao, C., Tagore, S., Ngo, B., Lee, M. J., … Izar, B. (2024). Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature Cancer, 5(3), 433–447. https://doi.org/10.1038/s43018-023-00704-x
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Vagelos College of Physicians and Surgeons; Department of Biochemistry and Molecular Biophysics; Department of Medicine; Division of Hematology/Oncology; Department of Pathology and Cell Biology; Department of Microbiology and Immunology; Department of Surgery; Division of Abdominal Organ Transplantation; Department of Radiology; Department of Systems Biology; Herbert Irving Comprehensive Cancer Center; Center for Translational Immunology
Kumar, D., Gurrapu, S., Wang, Y., Bae, S.-Y., Pandey, P. R., Chen, H., Mondal, J., Han, H., Wu, C.-J., Karaiskos, S., Yang, F., Sahin, A., Wistuba, I. I., Gao, J., Tripathy, D., Gao, H., Izar, B., & Giancotti, F. G. (2024). LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells. Nature Cancer, 5(2), 262–282. https://doi.org/10.1038/s43018-023-00695-9
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Hart, S. F. M., Yonemitsu, M. A., Giersch, R. M., Garrett, F. E. S., Beal, B. F., Arriagada, G., Davis, B. W., Ostrander, E. A., Goff, S. P., & Metzger, M. J. (2023). Centuries of genome instability and evolution in soft-shell clam, Mya arenaria, bivalve transmissible neoplasia. Nature Cancer, 4(11), 1561–1574. https://doi.org/10.1038/s43018-023-00643-7
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Su, Z., Kon, N., Yi, J., Zhao, H., Zhang, W., Tang, Q., Li, H., Kobayashi, H., Li, Z., Duan, S., Liu, Y., Olive, K. P., Zhang, Z., Honig, B., Manfredi, J. J., Rustgi, A. K., & Gu, W. (2023). Specific regulation of BACH1 by the hotspot mutant p53R175H reveals a distinct gain-of-function mechanism. Nature Cancer, 4(4), 564–581. https://doi.org/10.1038/s43018-023-00532-z
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Institute for Cancer Genetics; Department of Systems Biology; Vagelos College of Physicians and Surgeons; Department of Microbiology and Immunology; Department of Medicine; Division of Digestive and Liver Diseases; Department of Pediatrics; Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation; Department of Genetics and Development; Department of Biochemistry and Molecular Biophysics; Division of Nephrology; Herbert Irving Comprehensive Cancer Center; Department of Pathology and Cell Biology; Zuckerman Mind, Brain, and Behavior Institute
Migliozzi, S., Oh, Y. T., Hasanain, M., Garofano, L., D’Angelo, F., Najac, R. D., Picca, A., Bielle, F., Di Stefano, A. L., Lerond, J., Sarkaria, J. N., Ceccarelli, M., Sanson, M., Lasorella, A., & Iavarone, A. (2023). Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy. Nature Cancer, 4(2), 181–202. https://doi.org/10.1038/s43018-022-00510-x
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Zeleke, T. Z., Pan, Q., Chiuzan, C., Onishi, M., Li, Y., Tan, H., Alvarez, M. J., Honan, E., Yang, M., Chia, P. L., Mukhopadhyay, P., Kelly, S., Wu, R., Fenn, K., Trivedi, M. S., Accordino, M., Crew, K. D., Hershman, D. L., Maurer, M., … Silva, J. (2022). Network-based assessment of HDAC6 activity predicts preclinical and clinical responses to the HDAC6 inhibitor ricolinostat in breast cancer. Nature Cancer, 4(2), 257–275. https://doi.org/10.1038/s43018-022-00489-5
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Nobre, A. R., Dalla, E., Yang, J., Huang, X., Wullkopf, L., Risson, E., Razghandi, P., Anton, M. L., Zheng, W., Seoane, J. A., Curtis, C., Kenigsberg, E., Wang, J., & Aguirre-Ghiso, J. A. (2022). ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung. Nature Cancer, 3(10), 1165–1180. https://doi.org/10.1038/s43018-022-00424-8
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Boehm, K. M., Aherne, E. A., Ellenson, L., Nikolovski, I., Alghamdi, M., Vázquez-García, I., Zamarin, D., Long Roche, K., Liu, Y., Patel, D., Aukerman, A., Pasha, A., Rose, D., Selenica, P., Causa Andrieu, P. I., Fong, C., Capanu, M., Reis-Filho, J. S., Vanguri, R., … Shah, S. P. (2022). Multimodal data integration using machine learning improves risk stratification of high-grade serous ovarian cancer. Nature Cancer, 3(6), 723–733. https://doi.org/10.1038/s43018-022-00388-9
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Lopez-Bujanda, Z. A., Haffner, M. C., Chaimowitz, M. G., Chowdhury, N., Venturini, N. J., Patel, R. A., Obradovic, A., Hansen, C. S., Jacków, J., Maynard, J. P., Sfanos, K. S., Abate-Shen, C., Bieberich, C. J., Hurley, P. J., Selby, M. J., Korman, A. J., Christiano, A. M., De Marzo, A. M., & Drake, C. G. (2021). Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression. Nature Cancer, 2(8), 803–818. https://doi.org/10.1038/s43018-021-00227-3
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Vagelos College of Physicians and Surgeons; Department of Medicine; Department of Molecular Pharmacology and Therapeutics; Department of Pathology and Cell Biology; Division of Hematology/Oncology; Department of Systems Biology; Department of Urology; Center for Translational Immunology; Department of Dermatology; Herbert Irving Comprehensive Cancer Center; Department of Genetics and Development
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Arrieta, V. A., Chen, A. X., Kane, J. R., Kang, S. J., Kassab, C., Dmello, C., Zhao, J., Burdett, K. B., Upadhyayula, P. S., Lee-Chang, C., Shilati, J., Jaishankar, D., Chen, L., Gould, A., Zhang, D., Yuan, J., Zhao, W., Ling, X., Burks, J. K., … Sonabend, A. M. (2021). ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma. Nature Cancer, 2(12), 1372–1386. https://doi.org/10.1038/s43018-021-00260-2
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Menolfi, D., & Zha, S. (2021). Targeting BRCA-mutated tumors in mitosis. Nature Cancer, 2(12), 1296–1297. https://doi.org/10.1038/s43018-021-00293-7
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