Wu, L. W., Moy, R. H., Bhardwaj, N., Cho, K., Feng, G.-S., Kim, E. S., Lei, M., Liu, E. T., Maitra, A., Mori, M., Ng, I. O. L., Oshima, M., Pao, W., Park, B. H., Ramalingam, S., Rha, S. Y., Ryeom, S. W., Shaw, A. T., … Yang, J. C.-H. (2025). Strengthening Asian/Asian American, Native Hawaiian, and Pacific Islander Leadership in Cancer Research. Cancer Discovery, 15(2), 267–270. https://doi.org/10.1158/2159-8290.cd-24-1618

Chesner, L. N., Polesso, F., Graff, J. N., Hawley, J. E., Smith, A. K., Lundberg, A., Das, R., Shenoy, T., Sjöström, M., Zhao, F., Hu, Y.-M., Linder, S., Chen, W. S., Hawkins, R. M., Shrestha, R., Zhu, X., Foye, A., Li, H., Kim, L. M., … Moran, A. E. (2024). Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer. Cancer Discovery, 15(3), 481–494. https://doi.org/10.1158/2159-8290.cd-24-0559

(2024). Cancer in 2024. Cancer Discovery, 14(12), 2324–2331. https://doi.org/10.1158/2159-8290.cd-24-1451

FNU, T., Shi, P., Zhang, W., Chung, S. S. W., Damoci, C. B., Fang, Y., Chen, Q.-Y., Saqi, A., Huang, Y., Wu, X., Lu, C., Yang, D., Wang, T. C., & Que, J. (2024). Sympathetic Neurons Promote Small Cell Lung Cancer Through the Beta-2 Adrenergic Receptor. Cancer Discovery. https://doi.org/10.1158/2159-8290.cd-24-0718

Taylor, A. M. (2024). Cancer Genomes Sometimes Take the Longest Evolutionary Road. Cancer Discovery, 14(10), 1766–1767. https://doi.org/10.1158/2159-8290.cd-24-1017

Rekhtman, N., Tischfield, S. E., Febres-Aldana, C. A., Lee, J. J.-Koo., Chang, J. C., Herzberg, B. O., Selenica, P., Woo, H. J., Vanderbilt, C. M., Yang, S.-R., Xu, F., Bowman, A. S., da Silva, E. M., Noronha, A. M., Mandelker, D. L., Mehine, M., Mukherjee, S., Blanco-Heredia, J., Orgera, J. J., … Rudin, C. M. (2024). Chromothripsis-mediated small cell lung carcinoma. Cancer Discovery. https://doi.org/10.1158/2159-8290.cd-24-0286

Kobayashi, H., Iida, T., Ochiai, Y., Malagola, E., Zhi, X., White, R. A., Qian, J., Wu, F., Waterbury, Q. T., Tu, R., Zheng, B., LaBella, J. S., Zamechek, L. B., Ogura, A., Woods, S. L., Worthley, D. L., Enomoto, A., & Wang, T. C. (2024). Neuro-mesenchymal interaction mediated by a β2 adrenergic-nerve growth factor feedforward loop promotes colorectal cancer progression. Cancer Discovery. https://doi.org/10.1158/2159-8290.cd-24-0287

Singhal, A., Styers, H. C., Rub, J., Li, Z., Torborg, S. R., Kim, J. Y., Grbovic-Huezo, O., Feng, H., Tarcan, Z. Cagla., Sahin Ozkan, H., Hallin, J., Basturk, O., Yaeger, R., Christensen, J. G., Betel, D., Yan, Y., Chio, I. I. C., de Stanchina, E., & Tammela, T. (2024). A classical epithelial state drives acute resistance to KRAS inhibition in pancreas cancer. Cancer Discovery. https://doi.org/10.1158/2159-8290.cd-24-0740

Waarts, M. R., Mowla, S., Boileau, M., Martinez Benitez, A. R., Sango, J., Bagish, M., Fernandez-Maestre, I., Shan, Y., Eisman, S. E., Park, Y. C., Wereski, M., Csete, I., O’Connor, K., Romero-Vega, A. C., Miles, L. A., Xiao, W., Wu, X., Koche, R. P., Armstrong, S. A., … Levine, R. L. (2024). CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype Specific Vulnerability in IDH2- and TET2-Mutant Cells. Cancer Discovery. https://doi.org/10.1158/2159-8290.cd-23-1092

Zhang, X., Duan, S., Apostolou, P. E., Wu, X., Watanabe, J., Gallitto, M., Barron, T., Taylor, K. R., Woo, P. J., Hua, X., Zhou, H., Wei, H.-J., McQuillan, N., Kang, K.-D., Friedman, G. K., Canoll, P. D., Chang, K., Wu, C.-C., Hashizume, R., … Zhang, Z. (2024). CHD2 Regulates Neuron–Glioma Interactions in Pediatric Glioma. Cancer Discovery, OF1–OF23. https://doi.org/10.1158/2159-8290.cd-23-0012

Dunbar, A. J., Bowman, R. L., Park, Y. C., O’Connor, K., Izzo, F., Myers, R. M., Karzai, A., Zaroogian, Z., Kim, W. J., Fernández-Maestre, I., Waarts, M. R., Nazir, A., Xiao, W., Codilupi, T., Brodsky, M., Farina, M., Cai, L., Cai, S. F., Wang, B., … Levine, R. L. (2024). Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms. Cancer Discovery, 14(5), 737–751. https://doi.org/10.1158/2159-8290.cd-22-0952

Gilbertson, R. J., Behjati, S., Böttcher, A.-L., Bronner, M. E., Burridge, M., Clausing, H., Clifford, H., Danaher, T., Donovan, L. K., Drost, J., Eggermont, A. M. M., Emerson, C., Flores, M. G., Hamerlik, P., Jabado, N., Jones, A., Kaessmann, H., Kleinman, C. L., Kool, M., … Pfister, S. M. (2024). The Virtual Child. Cancer Discovery, 14(4), 663–668. https://doi.org/10.1158/2159-8290.cd-23-1500

Hasselluhn, M. C., Decker-Farrell, A. R., Vlahos, L., Thomas, D. H., Curiel-Garcia, A., Maurer, H. C., Wasko, U. N., Tomassoni, L., Sastra, S. A., Palermo, C. F., Dalton, T. C., Ma, A., Li, F., Tolosa, E. J., Hibshoosh, H., Fernandez-Zapico, M. E., Muir, A., Califano, A., & Olive, K. P. (2023). Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression. Cancer Discovery, 14(2), 348–361. https://doi.org/10.1158/2159-8290.cd-23-0240

Efe, G., Dunbar, K. J., Sugiura, K., Cunningham, K., Carcamo, S., Karaiskos, S., Tang, Q., Cruz-Acuña, R., Resnick-Silverman, L., Peura, J., Lu, C., Hasson, D., Klein-Szanto, A. J., Taylor, A. M., Manfredi, J. J., Prives, C., & Rustgi, A. K. (2023). p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression. Cancer Discovery, 13(12), 2632–2651. https://doi.org/10.1158/2159-8290.cd-23-0601

Varkaris, A., Pazolli, E., Gunaydin, H., Wang, Q., Pierce, L., Boezio, A. A., Bulku, A., DiPietro, L., Fridrich, C., Frost, A., Giordanetto, F., Hamilton, E. P., Harris, K., Holliday, M., Hunter, T. L., Iskandar, A., Ji, Y., Larivée, A., LaRochelle, J. R., … Kipp, D. R. (2023). Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia. Cancer Discovery, 14(2), 240–257. https://doi.org/10.1158/2159-8290.cd-23-0944

Kearney, A. L., & Vasan, N. (2023). A New Wave of PI3Kα Inhibitors. Cancer Discovery, 13(11), 2313–2315. https://doi.org/10.1158/2159-8290.cd-23-0945

Negrao, M. V., Araujo, H. A., Lamberti, G., Cooper, A. J., Akhave, N. S., Zhou, T., Delasos, L., Hicks, J. K., Aldea, M., Minuti, G., Hines, J., Aredo, J. V., Dennis, M. J., Chakrabarti, T., Scott, S. C., Bironzo, P., Scheffler, M., Christopoulos, P., Stenzinger, A., … Skoulidis, F. (2023). Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC. Cancer Discovery, 13(7), 1556–1571. https://doi.org/10.1158/2159-8290.cd-22-1420

Klapp, V., Álvarez-Abril, B., Leuzzi, G., Kroemer, G., Ciccia, A., & Galluzzi, L. (2023). The DNA Damage Response and Inflammation in Cancer. Cancer Discovery, 13(7), 1521–1545. https://doi.org/10.1158/2159-8290.cd-22-1220

Subbiah, V., Sahai, V., Maglic, D., Bruderek, K., Touré, B. B., Zhao, S., Valverde, R., O’Hearn, P. J., Moustakas, D. T., Schönherr, H., Gerami-Moayed, N., Taylor, A. M., Hudson, B. M., Houde, D. J., Pal, D., Foster, L., Gunaydin, H., Ayaz, P., Sharon, D. A., … Casaletto, J. B. (2023). RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity acrossFGFR2Alterations and Resistance Mutations. Cancer Discovery, 13(9), 2012–2031. https://doi.org/10.1158/2159-8290.cd-23-0475

Mundi, P. S., Dela Cruz, F. S., Grunn, A., Diolaiti, D., Mauguen, A., Rainey, A. R., Guillan, K., Siddiquee, A., You, D., Realubit, R., Karan, C., Ortiz, M. V., Douglass, E. F., Accordino, M., Mistretta, S., Brogan, F., Bruce, J. N., Caescu, C. I., Carvajal, R. D., … Califano, A. (2023). A Transcriptome-Based Precision Oncology Platform for Patient–Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies. Cancer Discovery, 13(6), 1386–1407. https://doi.org/10.1158/2159-8290.cd-22-1020

Choe, J. H., Kawase, T., Xu, A., Guzman, A., Obradovic, A. Z., Low-Calle, A. M., Alaghebandan, B., Raghavan, A., Long, K., Hwang, P. M., Schiffman, J. D., Zhu, Y., Zhao, R., Lee, D.-F., Katz, C., & Prives, C. (2023). Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death. Cancer Discovery, 13(5), 1250–1273. https://doi.org/10.1158/2159-8290.cd-22-0882

Ko, A., Hasanain, M., Oh, Y. T., D’Angelo, F., Sommer, D., Frangaj, B., Tran, S., Bielle, F., Pollo, B., Paterra, R., Mokhtari, K., Soni, R. K., Peyre, M., Eoli, M., Papi, L., Kalamarides, M., Sanson, M., Iavarone, A., & Lasorella, A. (2022). LZTR1Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL. Cancer Discovery, 13(3), 702–723. https://doi.org/10.1158/2159-8290.cd-22-0376

Vasciaveo, A., Arriaga, J. M., de Almeida, F. N., Zou, M., Douglass, E. F., Picech, F., Shibata, M., Rodriguez-Calero, A., de Brot, S., Mitrofanova, A., Chua, C. W., Karan, C., Realubit, R., Pampou, S., Kim, J. Y., Afari, S. N., Mukhammadov, T., Zanella, L., Corey, E., … Abate-Shen, C. (2022). OncoLoop: A Network-Based Precision Cancer Medicine Framework. Cancer Discovery, 13(2), 386–409. https://doi.org/10.1158/2159-8290.cd-22-0342

Mo, Y., Duan, S., Zhang, X., Hua, X., Zhou, H., Wei, H.-J., Watanabe, J., McQuillan, N., Su, Z., Gu, W., Wu, C.-C., Vakoc, C. R., Hashizume, R., Chang, K., & Zhang, Z. (2022). Epigenome Programming by H3.3K27M Mutation Creates a Dependence of Pediatric Glioma on SMARCA4. Cancer Discovery, 12(12), 2906–2929. https://doi.org/10.1158/2159-8290.cd-21-1492

Reglero, C., Dieck, C. L., Zask, A., Forouhar, F., Laurent, A. P., Lin, W.-H. W., Albero, R., Miller, H. I., Ma, C., Gastier-Foster, J. M., Loh, M. L., Tong, L., Stockwell, B. R., Palomero, T., & Ferrando, A. A. (2022). Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia. Cancer Discovery, 12(11), 2646–2665. https://doi.org/10.1158/2159-8290.cd-22-0010

Martini, R., Delpe, P., Chu, T. R., Arora, K., Lord, B., Verma, A., Bedi, D., Karanam, B., Elhussin, I., Chen, Y., Gebregzabher, E., Oppong, J. K., Adjei, E. K., Jibril Suleiman, A., Awuah, B., Muleta, M. B., Abebe, E., Kyei, I., Aitpillah, F. S., … Davis, M. B. (2022). African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent. Cancer Discovery, 12(11), 2530–2551. https://doi.org/10.1158/2159-8290.cd-22-0138

Goubet, A.-G., Lordello, L., Alves Costa Silva, C., Peguillet, I., Gazzano, M., Mbogning-Fonkou, M. D., Thelemaque, C., Lebacle, C., Thibault, C., Audenet, F., Pignot, G., Gravis, G., Helissey, C., Campedel, L., Roupret, M., Xylinas, E., Ouzaid, I., Dubuisson, A., Mazzenga, M., … Loriot, Y. (2022). Escherichia coli–Specific CXCL13-Producing TFH Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer. Cancer Discovery, 12(10), 2280–2307. https://doi.org/10.1158/2159-8290.cd-22-0201

Yeaton, A., Cayanan, G., Loghavi, S., Dolgalev, I., Leddin, E. M., Loo, C. E., Torabifard, H., Nicolet, D., Wang, J., Corrigan, K., Paraskevopoulou, V., Starczynowski, D. T., Wang, E., Abdel-Wahab, O., Viny, A. D., Stone, R. M., Byrd, J. C., Guryanova, O. A., Kohli, R. M., … Guillamot, M. (2022). The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation. Cancer Discovery, 12(10), 2392–2413. https://doi.org/10.1158/2159-8290.cd-21-1146

Galán-Díez, M., Borot, F., Ali, A. M., Zhao, J., Gil-Iturbe, E., Shan, X., Luo, N., Liu, Y., Huang, X.-P., Bisikirska, B., Labella, R., Kurland, I., Roth, B. L., Quick, M., Mukherjee, S., Rabadán, R., Carroll, M., Raza, A., & Kousteni, S. (2022). Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia. Cancer Discovery, 12(4), 1106–1127. https://doi.org/10.1158/2159-8290.cd-21-0692

Biswas, A. K., Han, S., Tai, Y., Ma, W., Coker, C., Quinn, S. A., Shakri, A. R., Zhong, T. J., Scholze, H., Lagos, G. G., Mela, A., Manova-Todorova, K., de Stanchina, E., Ferrando, A. A., Mendelsohn, C., Canoll, P., Yu, H. A., Paik, P. K., Saqi, A., … Acharyya, S. (2022). Targeting S100A9–ALDH1A1–Retinoic Acid Signaling to Suppress Brain Relapse inEGFR-Mutant Lung Cancer. Cancer Discovery, 12(4), 1002–1021. https://doi.org/10.1158/2159-8290.cd-21-0910

Rashkovan, M., Albero, R., Gianni, F., Perez-Duran, P., Miller, H. I., Mackey, A. L., Paietta, E. M., Tallman, M. S., Rowe, J. M., Litzow, M. R., Wiernik, P. H., Luger, S., Sulis, M. L., Soni, R. K., & Ferrando, A. A. (2022). Intracellular Cholesterol Pools Regulate Oncogenic Signaling and Epigenetic Circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia. Cancer Discovery, 12(3), 856–871. https://doi.org/10.1158/2159-8290.cd-21-0551