Janus Kinase 3

Subject Vocabulary
MeSH
Unique ID
D053616

Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata

Dai, Z., Sezin, T., Chang, Y., Lee, E. Y., Wang, E. H. C., & Christiano, A. M. (2022). Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.955038
Authors:
Zhenpeng Dai
Tanya Sezin
Yuqian Chang
Eunice Y Lee
Eddy Hsi Chun Wang
Angela M Christiano
Affiliated Authors:
Zhenpeng Dai
Tanya Sezin
Yuqian Chang
Eunice Y Lee
Eddy Hsi Chun Wang
Angela M Christiano
Columbia Affiliation:
Subjects:
Alopecia Areata (MeSH)
Autoimmune Diseases (MeSH)
Janus Kinase 1 (MeSH)
Janus Kinase 3 (MeSH)
Janus Kinase Inhibitors (MeSH)
Author Keywords:
alopecia aerata (aa)
t cell
gamma chain cytokines
jak
stat signaling pathway
t cell exhaustion
jak - stat signaling pathway
Grants:
P30AR069632 (NIH – National Institute of Arthritis and Musculoskeletal and Skin Diseases)
K01AR070291 (NIH – National Institute of Arthritis and Musculoskeletal and Skin Diseases)
P50AR070588 (NIH – National Institute of Arthritis and Musculoskeletal and Skin Diseases)
Publication Type:
Article
Unique ID:
10.3389/fimmu.2022.955038
PMID:
36203601
DOI:
10.3389/fimmu.2022.955038
Journal:
Frontiers in Immunology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created:

Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata

Dai, Z., Chen, J., Chang, Y., & Christiano, A. M. (2021). Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata. JCI Insight, 6(7). https://doi.org/10.1172/jci.insight.142205
Authors:
Zhenpeng Dai
James Chen
Yuqian Chang
Angela M Christiano
Affiliated Authors:
Angela M Christiano
Columbia Affiliation:
Subjects:
Alopecia Areata (MeSH)
Janus Kinase 3 (MeSH)
Protein Kinase Inhibitors (MeSH)
Author Keywords:
autoimmunity
inflammation
skin
t cells
Grants:
S10RR027050 (NIH – National Center for Research Resources)
P30AR069632 (NIH – National Institute of Arthritis and Musculoskeletal and Skin Diseases)
P50AR070588 (NIH – National Institute of Arthritis and Musculoskeletal and Skin Diseases)
K01AR070291 (NIH – National Institute of Arthritis and Musculoskeletal and Skin Diseases)
S10OD020056 (NIH – Office of the Director, National Institutes of Health)
Publication Type:
Article
Unique ID:
10.1172/jci.insight.142205
PMID:
33830087
DOI:
10.1172/jci.insight.142205
Journal:
JCI Insight
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record
View Scopus Record

Record Created:

CSV