Janus Kinase Inhibitors

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Nohria, A., Desai, D., Shapiro, J., Bordone, L., & Lo Sicco, K. (2024). Review of the use of Janus kinase inhibitors in the treatment of scarring alopecia. International Journal of Dermatology, 63(6). Portico. https://doi.org/10.1111/ijd.17153
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Son, A., Meylan, F., Gomez-Rodriguez, J., Kaul, Z., Sylvester, M., Falduto, G. H., Vazquez, E., Haque, T., Kitakule, M. M., Wang, C., Manthiram, K., Qi, C.-F., Cheng, J., Gurram, R. K., Zhu, J., Schwartzberg, P., Milner, J. D., Frischmeyer-Guerrerio, P. A., & Schwartz, D. M. (2023). Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation. Nature Immunology, 24(6), 1036–1048. https://doi.org/10.1038/s41590-023-01501-5
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Dai, Z., Sezin, T., Chang, Y., Lee, E. Y., Wang, E. H. C., & Christiano, A. M. (2022). Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.955038
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Ruperto, N., Brunner, H. I., Synoverska, O., Ting, T. V., Mendoza, C. A., Spindler, A., Vyzhga, Y., Marzan, K., Grebenkina, L., Tirosh, I., Imundo, L., Jerath, R., Kingsbury, D. J., Sozeri, B., Vora, S. S., Prahalad, S., Zholobova, E., Butbul Aviel, Y., Chasnyk, V., … Weiss, J. (2021). Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial. The Lancet, 398(10315), 1984–1996. https://doi.org/10.1016/s0140-6736(21)01255-1
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