Protein Kinase Inhibitors

Displaying 1 - 7 of 7CSV
Brettell, S. B., Janha, O., Begen, A., Cann, G., Sharma, S., Olaniyan, N., Yelland, T., Hole, A. J., Alam, B., Mayville, E., Gillespie, R., Capper, M., Fidock, D. A., Milligan, G., Clarke, D. J., Tobin, A. B., & Jamieson, A. G. (2024). Targeting PfCLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment. Journal of Medicinal Chemistry, 67(21), 18895–18910. https://doi.org/10.1021/acs.jmedchem.4c01300
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Wierda, W. G., Shah, N. N., Cheah, C. Y., Lewis, D., Hoffmann, M. S., Coombs, C. C., Lamanna, N., Ma, S., Jagadeesh, D., Munir, T., Wang, Y., Eyre, T. A., Rhodes, J. M., McKinney, M., Lech-Maranda, E., Tam, C. S., Jurczak, W., Izutsu, K., Alencar, A. J., … Ghia, P. (2024). Pirtobrutinib, a highly selective, non-covalent (reversible) BTK inhibitor in patients with B-cell malignancies: analysis of the Richter transformation subgroup from the multicentre, open-label, phase 1/2 BRUIN study. The Lancet Haematology, 11(9), e682–e692. https://doi.org/10.1016/s2352-3026(24)00172-8
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Mato, A. R., Woyach, J. A., Brown, J. R., Ghia, P., Patel, K., Eyre, T. A., Munir, T., Lech-Maranda, E., Lamanna, N., Tam, C. S., Shah, N. N., Coombs, C. C., Ujjani, C. S., Fakhri, B., Cheah, C. Y., Patel, M. R., Alencar, A. J., Cohen, J. B., Gerson, J. N., … Jurczak, W. (2023). Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia. New England Journal of Medicine, 389(1), 33–44. https://doi.org/10.1056/nejmoa2300696
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Piperno-Neumann, S., Carlino, M. S., Boni, V., Loirat, D., Speetjens, F. M., Park, J. J., Calvo, E., Carvajal, R. D., Nyakas, M., Gonzalez-Maffe, J., Zhu, X., Shirley, M. D., Ramkumar, T., Fessehatsion, A., Burks, H. E., Yerramilli-Rao, P., & Kapiteijn, E. (2023). A phase I trial of LXS196, a protein kinase C (PKC) inhibitor, for metastatic uveal melanoma. British Journal of Cancer, 128(6), 1040–1051. https://doi.org/10.1038/s41416-022-02133-6
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Ford, M., Mauro, M., Aftandilian, C., Sakamoto, K. M., & Hijiya, N. (2022). Management of Chronic Myeloid Leukemia in Children and Young Adults. Current Hematologic Malignancy Reports, 17(5), 121–126. https://doi.org/10.1007/s11899-022-00673-5
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Popmihajlov, Z., Sutherland, D. J., Horan, G. S., Ghosh, A., Lynch, D. A., Noble, P. W., Richeldi, L., Reiss, T. F., & Greenberg, S. (2022). CC-90001, a c-Jun N-terminal kinase (JNK) inhibitor, in patients with pulmonary fibrosis: design of a phase 2, randomised, placebo-controlled trial. BMJ Open Respiratory Research, 9(1), e001060. https://doi.org/10.1136/bmjresp-2021-001060
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