Age-Related Macular Degeneration Research

Displaying 1 - 50 of 52CSV
Jalili, J., Walker, E., Bowd, C., Belghith, A., Goldbaum, M. H., Fazio, M. A., Girkin, C. A., De Moraes, C. G., Liebmann, J. M., Weinreb, R. N., Zangwill, L. M., & Christopher, M. (2025). Deep Learning Approach Predicts Longitudinal Retinal Nerve Fiber Layer Thickness Changes. Bioengineering, 12(2), 139. https://doi.org/10.3390/bioengineering12020139
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Yeager, L. B., Li, C. Y., Bogolmony, D., Debelenko, L., & Marr, B. P. (2025). Vitreous Hemorrhage in Posterior Uveal Melanocytoma: Two Case Reports. Case Reports in Ophthalmological Medicine, 2025(1). Portico. https://doi.org/10.1155/crop/5126550
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Sassone, F., Estay-Ahumada, C., Roux, M. J., Ciocca, D., Rossolillo, P., Birling, M.-C., Sparrow, J. R., Montenegro, D., & Hicks, D. (2024). Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-81869-y
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Hood, D. C., La Bruna, S., Durbin, M., Lee, C., Guzman, A., Gebhardt, T., Wang, Y., Stowman, A. L., De Moraes, C. G., Chaglasian, M., & Tsamis, E. (2024). A Pattern-Based OCT Metric for Glaucoma Detection. Translational Vision Science & Technology, 13(12), 21. https://doi.org/10.1167/tvst.13.12.21
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Holste, G., Lin, M., Zhou, R., Wang, F., Liu, L., Yan, Q., Van Tassel, S. H., Kovacs, K., Chew, E. Y., Lu, Z., Wang, Z., & Peng, Y. (2024). Harnessing the power of longitudinal medical imaging for eye disease prognosis using Transformer-based sequence modeling. Npj Digital Medicine, 7(1). https://doi.org/10.1038/s41746-024-01207-4
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Fu, C., Yang, N., Chuang, J.-Z., Nakajima, N., Iraha, S., Roy, N., Wu, Z., Jiang, Z., Otsu, W., Radu, R. A., Yang, H. H., Lee, M. P., Worgall, T. S., Xiong, W.-C., & Sung, C.-H. (2024). Mutant mice with rod-specific VPS35 deletion exhibit retinal α-synuclein pathology-associated degeneration. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-50189-0
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Lin, T.-Y., Yu-Chuan Kang, E., Wang, N.-K., Kang, J.-H., Chen, K.-J., Wu, W.-C., Lai, C.-C., & Hwang, Y.-S. (2024). Association Between Pentoxifylline Use and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Multi-Institutional Cohort Study. Biomedical Journal, 100771. https://doi.org/10.1016/j.bj.2024.100771
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Kunala, K., Tang, J. A. H., Bowles Johnson, K. E., Huynh, K. T., Parkins, K., Kim, H.-J., Yang, Q., Sparrow, J. R., & Hunter, J. J. (2024). Near Infrared Autofluorescence Lifetime Imaging of Human Retinal Pigment Epithelium Using Adaptive Optics Scanning Light Ophthalmoscopy. Investigative Ophthalmology & Visual Science, 65(5), 27. https://doi.org/10.1167/iovs.65.5.27
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Singh, R. K., Smith, S., Fingert, J., Gordon, M., Kass, M., Scheetz, T., Segrè, A. V., Wiggs, J., Elze, T., & Zebardast, N. (2024). Machine Learning–Derived Baseline Visual Field Patterns Predict Future Glaucoma Onset in the Ocular Hypertension Treatment Study. Investigative Opthalmology & Visual Science, 65(2), 35. https://doi.org/10.1167/iovs.65.2.35
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El Husseini, N., Schaich, C. L., Craft, S., Rapp, S. R., Hayden, K. M., Sharrett, R., Cotch, M. F., Wong, T. Y., Luchsinger, J. A., Espeland, M. A., Baker, L. D., Bertoni, A. G., & Hughes, T. M. (2024). Retinal vessel caliber and cognitive performance: the multi-ethnic study of atherosclerosis (MESA). Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-54412-2
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Feenstra, H. M. A., van Dijk, E. H. C., Cheung, C. M. G., Ohno-Matsui, K., Lai, T. Y. Y., Koizumi, H., Larsen, M., Querques, G., Downes, S. M., Yzer, S., Breazzano, M. P., Subhi, Y., Tadayoni, R., Priglinger, S. G., Pauleikhoff, L. J. B., Lange, C. A. K., Loewenstein, A., Diederen, R. M. H., Schlingemann, R. O., … Boon, C. J. F. (2024). Central serous chorioretinopathy: An evidence-based treatment guideline. Progress in Retinal and Eye Research, 101, 101236. https://doi.org/10.1016/j.preteyeres.2024.101236
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Leshno, A., Tsamis, E., Hirji, S., Gomide, G. A., Harizman, N., De Moraes, C. G., Garg Shukla, A., Cioffi, G. A., Hood, D. C., & Liebmann, J. M. (2024). Detecting Established Glaucoma Using OCT Alone: Utilizing an OCT Reading Center in a Real-World Clinical Setting. Translational Vision Science & Technology, 13(1), 4. https://doi.org/10.1167/tvst.13.1.4
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Verma, S. S., Gudiseva, H. V., Chavali, V. R. M., Salowe, R. J., Bradford, Y., Guare, L., Lucas, A., Collins, D. W., Vrathasha, V., Nair, R. M., Rathi, S., Zhao, B., He, J., Lee, R., Zenebe-Gete, S., Bowman, A. S., McHugh, C. P., Zody, M. C., Pistilli, M., … O’Brien, J. M. (2024). A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma. Cell, 187(2), 464-480.e10. https://doi.org/10.1016/j.cell.2023.12.006
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Leshno, A., Tsamis, E., Harizman, N., De Moraes, C. G., La Bruna, S., Rai, A., Garg-Shukla, A., Cioffi, G. A., Wang, Q., Liebmann, J. M., & Hood, D. C. (2023). Improving glaucoma staging in clinical practice by combining the ICD-10 glaucoma severity classification system and optical coherence tomography. Eye, 38(1), 153–160. https://doi.org/10.1038/s41433-023-02650-5
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Cornelis, S. S., Bauwens, M., Haer-Wigman, L., De Bruyne, M., Pantrangi, M., De Baere, E., Hufnagel, R. B., Dhaenens, C.-M., & Cremers, F. P. M. (2023). Compendium of Clinical Variant Classification for 2,246 Unique ABCA4 Variants to Clarify Variant Pathogenicity in Stargardt Disease Using a Modified ACMG/AMP Framework. Human Mutation, 2023, 1–12. https://doi.org/10.1155/2023/6815504
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Zhao, J., Kim, H. J., Montenegro, D., Dunaief, J. L., & Sparrow, J. R. (2023). Iron overload and chelation modulates bisretinoid levels in the retina. Frontiers in Ophthalmology, 3. https://doi.org/10.3389/fopht.2023.1305864
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Hood, D. C., La Bruna, S., Leshno, A., Gomide, G. A., Kim, M. J., Cioffi, G. A., Liebmann, J. M., De Moraes, C. G., & Tsamis, E. (2023). A Model of Progression to Help Identify Macular Damage Due to Glaucoma. Investigative Opthalmology & Visual Science, 64(15), 8. https://doi.org/10.1167/iovs.64.15.8
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Levine, S. R., Myers, M. G., Barunas, R., Chang, D. S., Dutta, S., Maddess, T., Liebmann, J. M., Sherman, S., Eydelman, M., Sun, J. K., Chambers, W., Wickström, K., Luhmann, U. F. O., Pallinat, M., Glassman, A., Aiello, L. P., Markel, D. S., & Gardner, T. W. (2023). Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop. Translational Vision Science & Technology, 12(11), 33. https://doi.org/10.1167/tvst.12.11.33
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Lin, T.-Y., Wu, P.-L., Kang, E. Y.-C., Chi, Y.-C., Jenny, L. A., Lin, P.-H., Lee, C.-Y., Liu, C.-H., Liu, L., Yeh, L.-K., Chen, K.-J., Hwang, Y.-S., Wu, W.-C., Lai, C.-C., Hsiao, M.-C., Liu, P.-K., & Wang, N.-K. (2023). Clinical Characteristics and Genetic Variants in Taiwanese Patients With PROM1-Related Inherited Retinal Disorders. Investigative Opthalmology & Visual Science, 64(14), 25. https://doi.org/10.1167/iovs.64.14.25
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Rekova, P., Dostalova, G., Rob, D., Vaneckova, M., Pavlicova, M., Linhart, A., & Kemlink, D. (2023). Cerebrovascular Phenotype in Fabry Disease Patients Assessed by Ultrasound. Journal of Ultrasound in Medicine, 42(10), 2315–2330. Portico. https://doi.org/10.1002/jum.16254
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Mahmoudinezhad, G., Nishida, T., Weinreb, R. N., Baxter, S. L., Chang, A. C., Nikkhoy, N., Walker, E., Liebmann, J. M., Girkin, C. A., & Moghimi, S. (2023). Associations of smoking and alcohol consumption with the development of open angle glaucoma: a retrospective cohort study. BMJ Open, 13(10), e072163. https://doi.org/10.1136/bmjopen-2023-072163
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Moster, M. R., Shalaby, W. S., Myers, J. S., Razeghinejad, R., Ramesh, S., Katz, L. J., Kolomeyer, N. N., Lee, D., & Shukla, A. G. (2023). Evaluation of the Hypertensive Phase after Ahmed Glaucoma Valve Implantation in Neovascular Glaucoma. Journal of Current Glaucoma Practice, 17(2), 91–97. https://doi.org/10.5005/jp-journals-10078-1406
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Aiello, J. J., Bogart, M. C., Chan, W.-T., Holoman, N. C., Trobenter, T. D., Relf, C. E., Kleinman, D. M., De Vivo, D. C., & Samuels, I. S. (2023). Systemic Reduction of Glut1 Normalizes Retinal Dysfunction, Inflammation, and Oxidative Stress in the Retina of Spontaneous Type 2 Diabetic Mice. The American Journal of Pathology, 193(7), 927–938. https://doi.org/10.1016/j.ajpath.2023.04.003
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Greenstein, V. C., Castillejos, D. S., Tsang, S. H., Lee, W., Sparrow, J. R., Allikmets, R., Birch, D. G., & Hood, D. C. (2023). Monitoring Lesion Area Progression in Stargardt Disease: A Comparison of En Face Optical Coherence Tomography and Fundus Autofluorescence. Translational Vision Science & Technology, 12(5), 2. https://doi.org/10.1167/tvst.12.5.2
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Paavo, M., Lee, W., Parmann, R., Lima de Carvalho, J. R., Zernant, J., Tsang, S. H., Allikmets, R., & Sparrow, J. R. (2023). Insights Into PROM1-Macular Disease Using Multimodal Imaging. Investigative Opthalmology & Visual Science, 64(4), 27. https://doi.org/10.1167/iovs.64.4.27
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Tsamis, E., La Bruna, S., Rai, A., Leshno, A., Grossman, J., Cioffi, G., Liebmann, J. M., De Moraes, C. G., & Hood, D. C. (2023). Progression of Early Glaucomatous Damage: Performance of Summary Statistics From Optical Coherence Tomography and Perimetry. Translational Vision Science & Technology, 12(3), 19. https://doi.org/10.1167/tvst.12.3.19
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Huang, H.-C., Lai, C.-H., Kang, E. Y.-C., Chen, K.-J., Wang, N.-K., Liu, L., Hwang, Y.-S., Lai, C.-C., & Wu, W.-C. (2023). Retrospective Analysis of Surgical Outcomes on Axial Length Elongation in Eyes with Posterior and Combined Persistent Fetal Vasculature. International Journal of Molecular Sciences, 24(6), 5836. https://doi.org/10.3390/ijms24065836
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Kang, E. Y.-C., Lin, T.-Y., Garg, S. J., Wang, N.-K., Chen, L.-J., Huang, P.-W., Chan, M.-J., Chen, K.-J., Wu, W.-C., Lai, C.-C., & Hwang, Y.-S. (2023). The Association of Intravitreal Injections of Different Anti-Vascular Endothelial Growth Factor with Systemic Outcomes in Diabetic Patients. Journal of Personalized Medicine, 13(3), 544. https://doi.org/10.3390/jpm13030544
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Kolesnikova, M., Lima de Carvalho, J. R., Oh, J. K., Soucy, M., Demirkol, A., Kim, A. H., Tsang, S. H., & Breazzano, M. P. (2023). Phenotypic Variability of Retinal Disease Among a Cohort of Patients With Variants in the CLN Genes. Investigative Opthalmology & Visual Science, 64(3), 23. https://doi.org/10.1167/iovs.64.3.23
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Fan, R., Alipour, K., Bowd, C., Christopher, M., Brye, N., Proudfoot, J. A., Goldbaum, M. H., Belghith, A., Girkin, C. A., Fazio, M. A., Liebmann, J. M., Weinreb, R. N., Pazzani, M., Kriegman, D., & Zangwill, L. M. (2023). Detecting Glaucoma from Fundus Photographs Using Deep Learning without Convolutions. Ophthalmology Science, 3(1), 100233. https://doi.org/10.1016/j.xops.2022.100233
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Montenegro, D., Zhao, J., Kim, H. J., Shmarakov, I. O., Blaner, W. S., & Sparrow, J. R. (2022). Products of the visual cycle are detected in mice lacking retinol binding protein 4, the only known vitamin A carrier in plasma. Journal of Biological Chemistry, 298(12), 102722. https://doi.org/10.1016/j.jbc.2022.102722
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Thakoor, K. A., Yao, J., Bordbar, D., Moussa, O., Lin, W., Sajda, P., & Chen, R. W. S. (2022). A multimodal deep learning system to distinguish late stages of AMD and to compare expert vs. AI ocular biomarkers. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-06273-w
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Kim, A. H., Liu, P.-K., Chang, Y.-H., Kang, E. Y.-C., Wang, H.-H., Chen, N., Tseng, Y.-J., Seo, G. H., Lee, H., Liu, L., Chao, A.-N., Chen, K.-J., Hwang, Y.-S., Wu, W.-C., Lai, C.-C., Tsang, S. H., Hsiao, M.-C., & Wang, N.-K. (2022). Congenital Stationary Night Blindness: Clinical and Genetic Features. International Journal of Molecular Sciences, 23(23), 14965. https://doi.org/10.3390/ijms232314965
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Oh, J. K., Vargas Del Valle, J. G., Lima de Carvalho, J. R., Sun, Y. J., Levi, S. R., Ryu, J., Yang, J., Nagasaki, T., Emanuelli, A., Rasool, N., Allikmets, R., Sparrow, J. R., Izquierdo, N. J., Duncan, J. L., Mahajan, V. B., & Tsang, S. H. (2022). Expanding the phenotype of TTLL5-associated retinal dystrophy: a case series. Orphanet Journal of Rare Diseases, 17(1). https://doi.org/10.1186/s13023-022-02295-9
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Qian, T., Gong, Q., Shen, H., Li, C., Wang, G., Xu, X., Schrauwen, I., & Wang, W. (2022). Novel variants in the RDH5 Gene in a Chinese Han family with fundus albipunctatus. BMC Ophthalmology, 22(1). https://doi.org/10.1186/s12886-022-02301-5
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Kolesnikova, M., Lima de Carvalho, J. R., Parmann, R., Kim, A. H., Mahajan, V. B., Tsang, S. H., & Sparrow, J. R. (2022). Chorioretinal atrophy following voretigene neparvovec despite the presence of fundus autofluorescence. Molecular Genetics & Genomic Medicine, 10(11). Portico. https://doi.org/10.1002/mgg3.2038
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White, N. H., Pan, Q., Knowler, W. C., Schroeder, E. B., Dabelea, D., Chew, E. Y., Blodi, B., Goldberg, R. B., Pi-Sunyer, X., Darwin, C., Schlögl, M., Nathan, D. M., Bray, G. A., Gadde, K. M., Culbert, I. W., Arceneaux, J., Chatellier, A., Dragg, A., … Brown, M. B. (2022). Risk Factors for the Development of Retinopathy in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Experience. Diabetes Care, 45(11), 2653–2661. https://doi.org/10.2337/dc22-0860
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Hood, D. C., La Bruna, S., Tsamis, E., Leshno, A., Melchior, B., Grossman, J., Liebmann, J. M., & De Moraes, C. G. (2022). The 24-2 Visual Field Guided Progression Analysis Can Miss the Progression of Glaucomatous Damage of the Macula Seen Using OCT. Ophthalmology Glaucoma, 5(6), 614–627. https://doi.org/10.1016/j.ogla.2022.03.007
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Shokr, H., Lush, V., Dias, I. H., Ekárt, A., De Moraes, G., & Gherghel, D. (2022). The Use of Retinal Microvascular Function and Telomere Length in Age and Blood Pressure Prediction in Individuals with Low Cardiovascular Risk. Cells, 11(19), 3037. https://doi.org/10.3390/cells11193037
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Jones, A. V., Curtiss, D., Harris, C., Southerington, T., Hautalahti, M., Wihuri, P., Mäkelä, J., Kallionpää, R. E., Makkonen, E., Knopp, T., Mannermaa, A., Mäkinen, E., Moilanen, A.-M., Tezel, T. H., & Waheed, N. K. (2022). An assessment of prevalence of Type 1 CFI rare variants in European AMD, and why lack of broader genetic data hinders development of new treatments and healthcare access. PLOS ONE, 17(9), e0272260. https://doi.org/10.1371/journal.pone.0272260
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Gruslova, A., Vengrenyuk, Y., Buja, L. M., Litovsky, S., Maehara, A., Kini, A., Akasaka, T., Garcia-Garcia, H., Jang, I.-K., Dijkstra, J., Raber, L., & Feldman, M. (2022). TCT-312 International OCT Core Labs Can Identify Stable but Not Unstable Coronary Plaque. Journal of the American College of Cardiology, 80(12), B125. https://doi.org/10.1016/j.jacc.2022.08.365
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Melgarejo, J. D., Eijgen, J. V., Maestre, G. E., Al-Aswad, L. A., Thijs, L., Mena, L. J., Lee, J. H., Terwilliger, J. D., Petitto, M., Chávez, C. A., Brito, M., Calmon, G., Silva, E., Wei, D.-M., Cutsforth, E., Keer, K. V., Gustavo De Moraes, C., Vanassche, T., Janssens, S., … Zhang, Z.-Y. (2022). Open-Angle Glaucomatous Optic Neuropathy Is Related to Dips Rather Than Increases in the Mean Arterial Pressure Over 24-H. American Journal of Hypertension, 35(8), 703–714. https://doi.org/10.1093/ajh/hpac028
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White, N. H., Pan, Q., Knowler, W. C., Schroeder, E. B., Dabelea, D., Chew, E. Y., Blodi, B., Goldberg, R. B., Pi-Sunyer, X., Darwin, C., Schlögl, M., Nathan, D. M., Goldstein, B. J., Furlong, K., Smith, K. A., Mendoza, J., Wildman, W., Simmons, M., … Hivert, M.-F. (2022). The Effect of Interventions to Prevent Type 2 Diabetes on the Development of Diabetic Retinopathy: The DPP/DPPOS Experience. Diabetes Care, 45(7), 1640–1646. https://doi.org/10.2337/dc21-2417
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Villasana, G. A., Bradley, C., Elze, T., Myers, J. S., Pasquale, L., De Moraes, C. G., Wellik, S., Boland, M. V., Ramulu, P., Hager, G., Unberath, M., & Yohannan, J. (2022). Improving Visual Field Forecasting by Correcting for the Effects of Poor Visual Field Reliability. Translational Vision Science & Technology, 11(5), 27. https://doi.org/10.1167/tvst.11.5.27
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Nicolela Susanna, C., Nicolela Susanna, B., Nicolela Susanna, F., & Susanna Jr, R. (2022). Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity. Journal of Ophthalmic and Vision Research, 17(1). https://doi.org/10.18502/jovr.v17i1.10167
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Parmann, R., Tsang, S. H., Zernant, J., Allikmets, R., Greenstein, V. C., & Sparrow, J. R. (2022). Comparisons Among Optical Coherence Tomography and Fundus Autofluorescence Modalities as Measurements of Atrophy in ABCA4-Associated Disease. Translational Vision Science & Technology, 11(1), 36. https://doi.org/10.1167/tvst.11.1.36
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Lee, W., Zernant, J., Su, P.-Y., Nagasaki, T., Tsang, S. H., & Allikmets, R. (2022). A genotype-phenotype correlation matrix for ABCA4 disease based on long-term prognostic outcomes. JCI Insight, 7(2). https://doi.org/10.1172/jci.insight.156154
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Blodi, B. A., Domalpally, A., Tjaden, A. H., Barrett, N., Chew, E. Y., Knowler, W. C., Lee, C. G., Pi-Sunyer, X., Wallia, A., White, N. H., & Temprosa, M. (2022). Comparison of ETDRS 7-Field to 4-Widefield Digital Imaging in the Evaluation of Diabetic Retinopathy Severity. Translational Vision Science & Technology, 11(1), 13. https://doi.org/10.1167/tvst.11.1.13
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